Bryan Pfister - Academia.edu (original) (raw)

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Research paper thumbnail of Harvested human neurons engineered as live nervous tissue constructs: implications for transplantation

Journal of Neurosurgery, 2008

Object-Although neuron transplantation to repair the nervous system has shown promise in animal m... more Object-Although neuron transplantation to repair the nervous system has shown promise in animal models, there are few practical sources of viable neurons for clinical application and insufficient approaches to bridge extensive nerve damage in patients. Therefore, the authors sought a clinically relevant source of neurons that could be engineered into transplantable nervous tissue constructs. The authors chose to evaluate human dorsal root ganglion (DRG) neurons due to their robustness in culture.

Research paper thumbnail of Harvested human neurons engineered as live nervous tissue constructs: implications for transplantation

Journal of Neurosurgery, 2008

Object-Although neuron transplantation to repair the nervous system has shown promise in animal m... more Object-Although neuron transplantation to repair the nervous system has shown promise in animal models, there are few practical sources of viable neurons for clinical application and insufficient approaches to bridge extensive nerve damage in patients. Therefore, the authors sought a clinically relevant source of neurons that could be engineered into transplantable nervous tissue constructs. The authors chose to evaluate human dorsal root ganglion (DRG) neurons due to their robustness in culture.

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