Burak SEZENÖZ - Academia.edu (original) (raw)
Papers by Burak SEZENÖZ
Nephrology, dialysis, transplantation/Nephrology dialysis transplantation, May 1, 2024
Annals of Indian Academy of Neurology, Dec 31, 2022
The International Journal of Cardiovascular Imaging
Kafkas Journal of Medical Sciences, 2022
Aim: Autonomic dysfunction is one of the major contributors to atrial fibrillation (AF) developme... more Aim: Autonomic dysfunction is one of the major contributors to atrial fibrillation (AF) development and recurrence. Predicting AF using autonomic dysfunction parameters such as heart rate variability (HRV) and heart rate turbulence (HRT) in patients with risk factors may influence our daily practice. Thus we compare HRV and HRT measurements derived from 24 hours Holter ECG between paroxysmal AF (PAF) patients and healthy subjects.
The anatolian journal of cardiology, 2023
The Anatolian Journal of Cardiology is an international monthly periodical on cardiology publishe... more The Anatolian Journal of Cardiology is an international monthly periodical on cardiology published on independent, unbiased, double-blinded and peerreview principles. The journal's publication language is English however titles of articles, abstracts and Keywords are also published in Turkish on the journal's web site. The Anatolian Journal of Cardiology aims to publish qualified and original clinical, experimental and basic research on cardiology at the international level. The journal's scope also covers editorial comments, reviews of innovations in medical education and practice, case reports, original images, scientific letters, educational articles, letters to the editor, articles on publication ethics, diagnostic puzzles, and issues in social cardiology. The target readership includes academic members, specialists, residents, and general practitioners working in the fields of adult cardiology, pediatric cardiology, cardiovascular surgery and internal medicine.
The Anatolian Journal of Cardiology
The Anatolian Journal of Cardiology is an international monthly periodical on cardiology publishe... more The Anatolian Journal of Cardiology is an international monthly periodical on cardiology published on independent, unbiased, double-blinded and peerreview principles. The journal's publication language is English however titles of articles, abstracts and Keywords are also published in Turkish on the journal's web site. The Anatolian Journal of Cardiology aims to publish qualified and original clinical, experimental and basic research on cardiology at the international level. The journal's scope also covers editorial comments, reviews of innovations in medical education and practice, case reports, original images, scientific letters, educational articles, letters to the editor, articles on publication ethics, diagnostic puzzles, and issues in social cardiology. The target readership includes academic members, specialists, residents, and general practitioners working in the fields of adult cardiology, pediatric cardiology, cardiovascular surgery and internal medicine.
Europace, May 24, 2023
Funding Acknowledgements: Type of funding sources: None. Background: Atrial tachycardia (AT) is a... more Funding Acknowledgements: Type of funding sources: None. Background: Atrial tachycardia (AT) is a commonly encountered rhythm disorder in patients with underlying atrial scar. The role of late potential (LP) based mapping in the detection of AT critical isthmus has yet to be systematically evaluated. Purpose: We aimed to investigate the relationship between the atrial LPs (ALP) localization in sinus rhythm and the critical isthmus of re-entrant ATs in patients with underlying atrial low-voltage areas. Methods: Thirty-five symptomatic patients [mean age: 62 ±9, gender: 25 (71.4%) female] with left AT, who had undergone catheter ablation, were enrolled. Voltage and LP mapping were performed in sinus rhythm in both atriums. Low voltage areas and signals with continuous-fragmented morphology were tagged. Isochronal late activation mapping (ILAM) was also performed in all procedures. After induction of AT, activation mapping was performed during tachycardia in all patients to detect critical sites of the tachycardia. Results: Activation mapping indicated single re-entry in 30 patients and ≥1 re-entry in 5 patients. Localized re-entry was observed in 20 (51.2%) patients, macro re-entry in 18 (46.1%), and biatrial re-entry in 1(2.5%). The mean fractionated electrogram duration in the AT termination site was calculated at 134.3±46.7 ms and the mean bipolar voltage at 0.17±0.12 mV. The ALPs were tagged in 25 (64.1%) patients on the anterior wall, 12 (34.3%) on the roof, 5 (12.8%) on the septal wall and 2 (5.7%) in the Bachmann's Bundle region. All ALPs were in the latest activated zones of ILAM in patients with localized re-entry and predicted successful ablation sites to terminate the AT. Freedom from atrial tachyarrhythmias (ATAs) was 78.7% at six months during a mean follow-up duration of 338 ±226 days. Conclusion: Our findings demonstrated the utility of ALPs during sinus rhythm to predict the successful termination sites for left ATs. These areas displayed continuous-fragmented signal morphology during sinus/paced rhythm in correlation with the critical isthmus of AT detected during activation mapping.
The anatolian journal of cardiology, 2016
The anatolian journal of cardiology, Mar 1, 2019
Europace, May 24, 2023
Funding Acknowledgements: Type of funding sources: None. Background: Presence of left atrial low ... more Funding Acknowledgements: Type of funding sources: None. Background: Presence of left atrial low voltage area (LVA) is an independent predictor of atrial tachyarhythmia (ATa) recurrences after atrial fibrillation (AF) ablation. Thus identifying patients with LVA by using non-invasive methods is an important endeavour. Purpose: In this study; we investigated the predictors of LVA and postablation recurrences especially focusing on clinical risk scores. Methods: We enrolled 328 consecutive patients who underwent initial AF ablation procedure using high density mapping. LVAs were assessed and segmental distribution was noted in each patient. CHA2DS2-VASc, HATCH, APPLE and SPEED scores were calculated. Predictive value and arrhythmia recurrences were evaluated. Results: Two hundred and twenty one patients (67.37%) were paroxysmal AF and 107 (32.62%) patients were non-paroxysmal AF at the time of ablation. Mean CHA2DS2-VASc score was 1.88±1.66, mean APPLE score was 1.20±1.20, HATCH score was 0.93±1.00 and SPEED score was 1.54±1.27 in the whole study group. LVA was detected in 131 patients (39.93%). Female gender [
Journal of Cardiovascular Electrophysiology
BackgroundAtrial tachycardia (AT) is a commonly encountered rhythm disorder in patients with unde... more BackgroundAtrial tachycardia (AT) is a commonly encountered rhythm disorder in patients with underlying atrial scar. The role of atrial late activation mapping during sinus rhythm to predict the critical isthmus (CI) of AT has yet to be systematically evaluated. We aimed to investigate the relationship between the functional substrate mapping (FSM) characteristics and the CI of reentrant ATs in patients with underlying atrial low‐voltage areas.MethodsPatients with history of left AT who underwent catheter ablation with 3D mapping using high‐density mapping were enrolled. Voltage map and isochronal late activation mapping were created during sinus/paced rhythm to detect deceleration zones (DZ). Electrograms with continuous‐fragmented morphology were also tagged. After induction of AT, activation mapping was performed to detect CI of the tachycardia. Atrial tachyarrhythmia (ATa) recurrence was defined as detection of atrial fibrillation or AT (≥30 s) during the follow‐up.ResultsAmong ...
The Journal of Thoracic and Cardiovascular Surgery, 2007
Objective: Atrial fibrillation is one of the most common complications after cardiac surgery. Thi... more Objective: Atrial fibrillation is one of the most common complications after cardiac surgery. This study evaluates the risk factors of paroxysmal atrial fibrillation in patients who underwent aortic valve replacement. Methods: The study comprised 300 patients with aortic valve defects of either aortic stenosis (n ϭ 150) or regurgitation (n ϭ 150) who underwent aortic valve replacement. For each patient, 2-mode and Doppler echocardiographic examinations were performed in the preoperative period, early postoperative period, and long-term observation, and selected hemodynamic parameters were analyzed. Results: Factors significantly associated with atrial fibrillation in patients with aortic stenosis were heart failure (odds ratio ϭ 5.5), age 70 years or more (4.5), low (3.9) and high body mass index (1.7), maximal transvalvular gradient (3.7), low left ventricular ejection fraction (5.1), end-systolic (2.9) and end-diastolic intraventricular septum thickness (1.5), and insignificant mitral regurgitation (1.9) in the preoperative period; and left ventricular ejection fraction (4.4) and end-systolic intraventricular septum thickness (1.8) in the early postoperative period. In the aortic regurgitation group, factors significantly associated with atrial fibrillation were age (1.8), left ventricular ejection fraction (3.7), left ventricular end-systolic diameter (1.7), end-diastolic intraventricular septum thickness (1.7), left atrium dimension (4.1) and insignificant mitral regurgitation (2.5) in the postoperative period; essential arterial hypertension (3.3), diabetes mellitus (2.6), and heart failure in the history (4.5) in the preoperative period; and left ventricular ejection fraction (1.9) and left atrium dimension (2.9) in the early postoperative period. Conclusion: On the basis of the separated risk factors, all patients should be preoperatively classified to applicable groups of risk of postoperative atrial fibrillation appearance, and the prophylactic treatment should be administered in the group of patients with the highest risk. It may essentially decrease the rate of complications and deaths, and, consequently, the costs of postoperative medical care. A trial fibrillation (AF), especially paroxysmal AF, is one of the most common complications after cardiac surgery. According to various authors, it occurs with a frequency of 10% to 50%, depending on the definition and diagnostic method. 1 AF usually occurs 2 to 4 days after surgery and often returns during the first 30 days of the postoperative period. 2,3 Recently, AF has been noted more often, probably because more patients undergo surgery in worse conditions, often associated with essential organic changes of heart. More postoperative arrhythmias are also connected with the broadening group of patients undergoing open procedures and thereby are the result of a reduction in contraindications. Suitable treatment and prevention of postoperative AF are important for patients' improved health and faster rehabilitation, and for reduced hospitalization costs resulting from shorter lengths of stay in the hospital. 4,5 Despite the existence of unique guidelines
American Journal of Nephrology, 2017
Background: Increased mortality and morbidity are reported in association with high ultrafiltrati... more Background: Increased mortality and morbidity are reported in association with high ultrafiltration rate (UFR) and with long dialysis recovery time (DRT). We studied the association between UFR and DRT. Methods: This is a cross-sectional, observational study was conducted. Patients on thrice-weekly hemodialysis (HD) with self-reported DRT between August and December 2014 were included. We examined the association of 30-day average UFR with recovery time. Results: The total number of patients included in this study was 2,689. DRT in categories of immediate recovery, >0-≤2, >2-≤6, >6-≤12, and >12 h, were reported in 27, 28, 17, 9, and 20% of the patients respectively. In multivariable analysis, longer DRT was associated with female gender, non-black race, higher body weight, lower serum albumin, chronic heart failure, cerebrovascular disease, missed dialysis sessions, higher pre-dialysis systolic blood pressure, and larger UF volume. Compared to UFR of <10, UFR ≥13 mL/k...
European Journal of Therapeutics
Gulhane Medical Journal, 2022
Aims: Cardiac dysautonomia and arrhythmias can occur in chronic inflammatory conditions such as f... more Aims: Cardiac dysautonomia and arrhythmias can occur in chronic inflammatory conditions such as familial Mediterranean fever (FMF). The aim of this study was to evaluate the cardiac autonomic functions in patients with FMF. Methods: This was a retrospective case-control study. Electrocardiography (ECG) and 24-hour Holter ECG recordings were obtained from the medical records. T-peak to Tend intervals (Tp-e) and Tp-e/corrected QT (QTc) ratio were calculated on ECG. Heart rate variability (HRV) parameters and heart rate turbulence (HRT) parameters including turbulence onset (TO) and turbulence slope (TS) were evaluated using the 24-hour Holter ECG. All subjects were divided into three groups according to HRT parameters
Cardiovascular Drugs and Therapy, 2020
Cryoballoon technology is a well-established method to provide pulmonary vein isolation in the tr... more Cryoballoon technology is a well-established method to provide pulmonary vein isolation in the treatment of atrial fibrillation. Additional lesions such as roof line, posterior wall isolation or left atrial appendage isolation also possible with the same technique. We report a case with roof dependent atrial tachycardia successully terminated by using cryoballoon following pulmonary vein isolation.
Nephrology, dialysis, transplantation/Nephrology dialysis transplantation, May 1, 2024
Annals of Indian Academy of Neurology, Dec 31, 2022
The International Journal of Cardiovascular Imaging
Kafkas Journal of Medical Sciences, 2022
Aim: Autonomic dysfunction is one of the major contributors to atrial fibrillation (AF) developme... more Aim: Autonomic dysfunction is one of the major contributors to atrial fibrillation (AF) development and recurrence. Predicting AF using autonomic dysfunction parameters such as heart rate variability (HRV) and heart rate turbulence (HRT) in patients with risk factors may influence our daily practice. Thus we compare HRV and HRT measurements derived from 24 hours Holter ECG between paroxysmal AF (PAF) patients and healthy subjects.
The anatolian journal of cardiology, 2023
The Anatolian Journal of Cardiology is an international monthly periodical on cardiology publishe... more The Anatolian Journal of Cardiology is an international monthly periodical on cardiology published on independent, unbiased, double-blinded and peerreview principles. The journal's publication language is English however titles of articles, abstracts and Keywords are also published in Turkish on the journal's web site. The Anatolian Journal of Cardiology aims to publish qualified and original clinical, experimental and basic research on cardiology at the international level. The journal's scope also covers editorial comments, reviews of innovations in medical education and practice, case reports, original images, scientific letters, educational articles, letters to the editor, articles on publication ethics, diagnostic puzzles, and issues in social cardiology. The target readership includes academic members, specialists, residents, and general practitioners working in the fields of adult cardiology, pediatric cardiology, cardiovascular surgery and internal medicine.
The Anatolian Journal of Cardiology
The Anatolian Journal of Cardiology is an international monthly periodical on cardiology publishe... more The Anatolian Journal of Cardiology is an international monthly periodical on cardiology published on independent, unbiased, double-blinded and peerreview principles. The journal's publication language is English however titles of articles, abstracts and Keywords are also published in Turkish on the journal's web site. The Anatolian Journal of Cardiology aims to publish qualified and original clinical, experimental and basic research on cardiology at the international level. The journal's scope also covers editorial comments, reviews of innovations in medical education and practice, case reports, original images, scientific letters, educational articles, letters to the editor, articles on publication ethics, diagnostic puzzles, and issues in social cardiology. The target readership includes academic members, specialists, residents, and general practitioners working in the fields of adult cardiology, pediatric cardiology, cardiovascular surgery and internal medicine.
Europace, May 24, 2023
Funding Acknowledgements: Type of funding sources: None. Background: Atrial tachycardia (AT) is a... more Funding Acknowledgements: Type of funding sources: None. Background: Atrial tachycardia (AT) is a commonly encountered rhythm disorder in patients with underlying atrial scar. The role of late potential (LP) based mapping in the detection of AT critical isthmus has yet to be systematically evaluated. Purpose: We aimed to investigate the relationship between the atrial LPs (ALP) localization in sinus rhythm and the critical isthmus of re-entrant ATs in patients with underlying atrial low-voltage areas. Methods: Thirty-five symptomatic patients [mean age: 62 ±9, gender: 25 (71.4%) female] with left AT, who had undergone catheter ablation, were enrolled. Voltage and LP mapping were performed in sinus rhythm in both atriums. Low voltage areas and signals with continuous-fragmented morphology were tagged. Isochronal late activation mapping (ILAM) was also performed in all procedures. After induction of AT, activation mapping was performed during tachycardia in all patients to detect critical sites of the tachycardia. Results: Activation mapping indicated single re-entry in 30 patients and ≥1 re-entry in 5 patients. Localized re-entry was observed in 20 (51.2%) patients, macro re-entry in 18 (46.1%), and biatrial re-entry in 1(2.5%). The mean fractionated electrogram duration in the AT termination site was calculated at 134.3±46.7 ms and the mean bipolar voltage at 0.17±0.12 mV. The ALPs were tagged in 25 (64.1%) patients on the anterior wall, 12 (34.3%) on the roof, 5 (12.8%) on the septal wall and 2 (5.7%) in the Bachmann's Bundle region. All ALPs were in the latest activated zones of ILAM in patients with localized re-entry and predicted successful ablation sites to terminate the AT. Freedom from atrial tachyarrhythmias (ATAs) was 78.7% at six months during a mean follow-up duration of 338 ±226 days. Conclusion: Our findings demonstrated the utility of ALPs during sinus rhythm to predict the successful termination sites for left ATs. These areas displayed continuous-fragmented signal morphology during sinus/paced rhythm in correlation with the critical isthmus of AT detected during activation mapping.
The anatolian journal of cardiology, 2016
The anatolian journal of cardiology, Mar 1, 2019
Europace, May 24, 2023
Funding Acknowledgements: Type of funding sources: None. Background: Presence of left atrial low ... more Funding Acknowledgements: Type of funding sources: None. Background: Presence of left atrial low voltage area (LVA) is an independent predictor of atrial tachyarhythmia (ATa) recurrences after atrial fibrillation (AF) ablation. Thus identifying patients with LVA by using non-invasive methods is an important endeavour. Purpose: In this study; we investigated the predictors of LVA and postablation recurrences especially focusing on clinical risk scores. Methods: We enrolled 328 consecutive patients who underwent initial AF ablation procedure using high density mapping. LVAs were assessed and segmental distribution was noted in each patient. CHA2DS2-VASc, HATCH, APPLE and SPEED scores were calculated. Predictive value and arrhythmia recurrences were evaluated. Results: Two hundred and twenty one patients (67.37%) were paroxysmal AF and 107 (32.62%) patients were non-paroxysmal AF at the time of ablation. Mean CHA2DS2-VASc score was 1.88±1.66, mean APPLE score was 1.20±1.20, HATCH score was 0.93±1.00 and SPEED score was 1.54±1.27 in the whole study group. LVA was detected in 131 patients (39.93%). Female gender [
Journal of Cardiovascular Electrophysiology
BackgroundAtrial tachycardia (AT) is a commonly encountered rhythm disorder in patients with unde... more BackgroundAtrial tachycardia (AT) is a commonly encountered rhythm disorder in patients with underlying atrial scar. The role of atrial late activation mapping during sinus rhythm to predict the critical isthmus (CI) of AT has yet to be systematically evaluated. We aimed to investigate the relationship between the functional substrate mapping (FSM) characteristics and the CI of reentrant ATs in patients with underlying atrial low‐voltage areas.MethodsPatients with history of left AT who underwent catheter ablation with 3D mapping using high‐density mapping were enrolled. Voltage map and isochronal late activation mapping were created during sinus/paced rhythm to detect deceleration zones (DZ). Electrograms with continuous‐fragmented morphology were also tagged. After induction of AT, activation mapping was performed to detect CI of the tachycardia. Atrial tachyarrhythmia (ATa) recurrence was defined as detection of atrial fibrillation or AT (≥30 s) during the follow‐up.ResultsAmong ...
The Journal of Thoracic and Cardiovascular Surgery, 2007
Objective: Atrial fibrillation is one of the most common complications after cardiac surgery. Thi... more Objective: Atrial fibrillation is one of the most common complications after cardiac surgery. This study evaluates the risk factors of paroxysmal atrial fibrillation in patients who underwent aortic valve replacement. Methods: The study comprised 300 patients with aortic valve defects of either aortic stenosis (n ϭ 150) or regurgitation (n ϭ 150) who underwent aortic valve replacement. For each patient, 2-mode and Doppler echocardiographic examinations were performed in the preoperative period, early postoperative period, and long-term observation, and selected hemodynamic parameters were analyzed. Results: Factors significantly associated with atrial fibrillation in patients with aortic stenosis were heart failure (odds ratio ϭ 5.5), age 70 years or more (4.5), low (3.9) and high body mass index (1.7), maximal transvalvular gradient (3.7), low left ventricular ejection fraction (5.1), end-systolic (2.9) and end-diastolic intraventricular septum thickness (1.5), and insignificant mitral regurgitation (1.9) in the preoperative period; and left ventricular ejection fraction (4.4) and end-systolic intraventricular septum thickness (1.8) in the early postoperative period. In the aortic regurgitation group, factors significantly associated with atrial fibrillation were age (1.8), left ventricular ejection fraction (3.7), left ventricular end-systolic diameter (1.7), end-diastolic intraventricular septum thickness (1.7), left atrium dimension (4.1) and insignificant mitral regurgitation (2.5) in the postoperative period; essential arterial hypertension (3.3), diabetes mellitus (2.6), and heart failure in the history (4.5) in the preoperative period; and left ventricular ejection fraction (1.9) and left atrium dimension (2.9) in the early postoperative period. Conclusion: On the basis of the separated risk factors, all patients should be preoperatively classified to applicable groups of risk of postoperative atrial fibrillation appearance, and the prophylactic treatment should be administered in the group of patients with the highest risk. It may essentially decrease the rate of complications and deaths, and, consequently, the costs of postoperative medical care. A trial fibrillation (AF), especially paroxysmal AF, is one of the most common complications after cardiac surgery. According to various authors, it occurs with a frequency of 10% to 50%, depending on the definition and diagnostic method. 1 AF usually occurs 2 to 4 days after surgery and often returns during the first 30 days of the postoperative period. 2,3 Recently, AF has been noted more often, probably because more patients undergo surgery in worse conditions, often associated with essential organic changes of heart. More postoperative arrhythmias are also connected with the broadening group of patients undergoing open procedures and thereby are the result of a reduction in contraindications. Suitable treatment and prevention of postoperative AF are important for patients' improved health and faster rehabilitation, and for reduced hospitalization costs resulting from shorter lengths of stay in the hospital. 4,5 Despite the existence of unique guidelines
American Journal of Nephrology, 2017
Background: Increased mortality and morbidity are reported in association with high ultrafiltrati... more Background: Increased mortality and morbidity are reported in association with high ultrafiltration rate (UFR) and with long dialysis recovery time (DRT). We studied the association between UFR and DRT. Methods: This is a cross-sectional, observational study was conducted. Patients on thrice-weekly hemodialysis (HD) with self-reported DRT between August and December 2014 were included. We examined the association of 30-day average UFR with recovery time. Results: The total number of patients included in this study was 2,689. DRT in categories of immediate recovery, >0-≤2, >2-≤6, >6-≤12, and >12 h, were reported in 27, 28, 17, 9, and 20% of the patients respectively. In multivariable analysis, longer DRT was associated with female gender, non-black race, higher body weight, lower serum albumin, chronic heart failure, cerebrovascular disease, missed dialysis sessions, higher pre-dialysis systolic blood pressure, and larger UF volume. Compared to UFR of <10, UFR ≥13 mL/k...
European Journal of Therapeutics
Gulhane Medical Journal, 2022
Aims: Cardiac dysautonomia and arrhythmias can occur in chronic inflammatory conditions such as f... more Aims: Cardiac dysautonomia and arrhythmias can occur in chronic inflammatory conditions such as familial Mediterranean fever (FMF). The aim of this study was to evaluate the cardiac autonomic functions in patients with FMF. Methods: This was a retrospective case-control study. Electrocardiography (ECG) and 24-hour Holter ECG recordings were obtained from the medical records. T-peak to Tend intervals (Tp-e) and Tp-e/corrected QT (QTc) ratio were calculated on ECG. Heart rate variability (HRV) parameters and heart rate turbulence (HRT) parameters including turbulence onset (TO) and turbulence slope (TS) were evaluated using the 24-hour Holter ECG. All subjects were divided into three groups according to HRT parameters
Cardiovascular Drugs and Therapy, 2020
Cryoballoon technology is a well-established method to provide pulmonary vein isolation in the tr... more Cryoballoon technology is a well-established method to provide pulmonary vein isolation in the treatment of atrial fibrillation. Additional lesions such as roof line, posterior wall isolation or left atrial appendage isolation also possible with the same technique. We report a case with roof dependent atrial tachycardia successully terminated by using cryoballoon following pulmonary vein isolation.