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Conference Presentations by C. N. Chineme

Research paper thumbnail of Pre-treatment with high dose vitamin A palmitate significantly enhances antibody response, reduces parasitaemia and improves survivability in experimental Trypanosoma brucei infection.

Papers by C. N. Chineme

Research paper thumbnail of Effect of varied fermentation periods on the diabetogenic potential of toasted cassava granules

Plant foods for human nutrition (Dordrecht, Netherlands), 1999

The effects of exclusive gari diets prepared using varied fermentation periods on the fasting blo... more The effects of exclusive gari diets prepared using varied fermentation periods on the fasting blood glucose levels (FBGL) and glucose tolerance (GT) of rats were studied. Thirty growing male albino rats divided randomly into 5 groups of 6 rats each were used. The 5 groups were each fed gari diets fermented for 0, 24, 48, 72 hours; and a standard rat diet, respectively, for 8 weeks. Data on the total cyanogen content and % crude protein of the diets; FBGL, GT, body weight, water:feed consumption ratio and clinical observations of the rats were collected. Results showed that the total cyanogen content and % crude protein of the diets were depleted as fermentation periods increased. The FBGL of all the gari-fed rats were significantly elevated and their GT significantly impaired with a significant variation between the groups. The elevated FBGL and impaired GT which were found to increase with increase in fermentation period were strongly inversely correlated to the % crude protein con...

Research paper thumbnail of Investigations into the toxicity of the leaves of Erythrophleum guineense Don. in sheep

Research in veterinary science, 1980

An investigation was carried out on the toxicity of the leaves of Erythrophleum guineense Don. in... more An investigation was carried out on the toxicity of the leaves of Erythrophleum guineense Don. in sheep. Four groups of two animals each were fed 8, 2, 0.5 and 0.25 g/kg/day, respectively, of dried ground leaves of E guineense through a stomach tube. Two animals served as controls and received 8 g/kg/day of ground grass hay through a stomach tube. Animals which received 8 g/kg of E guineense died within 3 h; those which received 2 g/kg died within 18 h, while those which received 0.5 and 0.25 g/kg developed clinical signs after being fed for two to four days and died between two and 14 days. Clinical signs observed were coma and convulsions in animals which died within 18 h. Animals which died after several days of sickness had signs of depression, dyspnoea, groaning, trembling of hind limbs, strong heart beat and severe dysentery. Pathological changes observed post mortem were varied and occurred in a number of organs.

Research paper thumbnail of Toxic effects of the leaves of Erythrophleum africanum Harms in sheep

Bulletin of animal health and production in Africa. Bulletin des santé et production animales en Afrique, 1981

Research paper thumbnail of Ringworm caused by Trichophyton verrucosum in young goats: a case report

Bulletin of animal health and production in Africa. Bulletin des santé et production animales en Afrique, 1981

Research paper thumbnail of A survey of causes of organ condemnation in slaughtered cattle at Zaria, Nigeria

Bulletin of animal health and production in Africa. Bulletin des santé et production animales en Afrique, 1980

Research paper thumbnail of Incidence and importance of chronic mastitis in Nigeria goats

Bulletin of animal health and production in Africa. Bulletin des santé et production animales en Afrique, 1980

Research paper thumbnail of Clinical and epidemiological features of peste des petits ruminants in Sokoto Red goats

Revue d'élevage et de médecine vétérinaire des pays tropicaux, 1986

Research paper thumbnail of Ovine nasal adenopapilloma: incidence and clinicopathologic studies

American journal of veterinary research, 1978

Nasal adenopapillomas were observed in 9 Y'anKasa and 1 Y'anKasa-Suffolk crossbred sheep ... more Nasal adenopapillomas were observed in 9 Y'anKasa and 1 Y'anKasa-Suffolk crossbred sheep (8 females and 2 males) over a 20-month period. The neoplasms originated from the epithelium of the lateral mass of the ethmoid bone. Gross and histologic features and clinical signs were similar in all cases. Influence of sex, age, or genetics was not established.

Research paper thumbnail of Pathology of acute intestinal coccidiosis in young goats

Bulletin of animal health and production in Africa. Bulletin des santé et production animales en Afrique, 1979

Research paper thumbnail of Clinicopathologic implications of shortened fermentation periods in the production of toasted cassava granules (gari)

Plant Foods for Human Nutrition, 2003

Research paper thumbnail of Gastrointestinal globidiosis of Yankasa sheep in Nigeria

Veterinary Record, 1978

The first report of globidial gastroenteritis of sheep in Nigeria is presented. Clinical symptoms... more The first report of globidial gastroenteritis of sheep in Nigeria is presented. Clinical symptoms, gross and histopathological lesions associated with the disease in nine adult rams are described. The importance of differentiating the disease from intestinal coccidiosis in Yankasa sheep is stressed.

Research paper thumbnail of Intestinal leiomyoma in a cow

Veterinary Record, 1979

A 10-year-old white Fulani Bunaji cow with clinical signs of ruminal stasis and melaena, was euth... more A 10-year-old white Fulani Bunaji cow with clinical signs of ruminal stasis and melaena, was euthanised following discovery of a neoplasm in the spiral colon. Histopathological examination revealed a leiomyoma.

Research paper thumbnail of Microcephaly associated with kyphoscoliosis and cleft palate in a Yankassa lamb

Research paper thumbnail of Canine cyclopia

Research paper thumbnail of Enteritis associated with Eimeria leuckarti infection in donkeys

Research paper thumbnail of Acute toxicity and gastrointestinal irritant effect ofCroton penduliflorus seed oil in mice

Phytotherapy Research, 1988

... Acknowledgements This work was supported by the University of Nigeria Senate Research Grant N... more ... Acknowledgements This work was supported by the University of Nigeria Senate Research Grant No. 00422/81. The authors are grateful to Mr Udenyi of the Veterinary Anatomy department of this University. 0 Heyden & Son Limited, 1988 PHYTOTHERAPY RESEARCH, VOL. ...

Research paper thumbnail of DEGENERATIVE CARDIOMYOPATHY IN A CAPTIVE KANGAROO (Macropus giganteus)

Journal of Wildlife Diseases, 1978

Myocardial degeneration and necrosis in an adult female Australian kangaroo (Macropus giganteus) ... more Myocardial degeneration and necrosis in an adult female Australian kangaroo (Macropus giganteus) are described. The animal was housed in a zoo at Kano, Nigeria for approximately five years before death. This is believed to be the first reported case of degenerative cardiomyopathy in a captive marsupial in Nigeria.

Research paper thumbnail of PATHOLOGIC CHANGES IN LIZARDS (Agama agama) EXPERIMENTALLY INFECTED WITH Dermatophilus congolensis

Journal of Wildlife Diseases, 1980

Captive laboratory-held lizards (Agama agama) experimentally inoculated with Dermatophilus congol... more Captive laboratory-held lizards (Agama agama) experimentally inoculated with Dermatophilus congolensis by subcutaneous, intramuscular and intraperitoneal routes developed pyogranulomatous and necrotic lesions at and around the sites of inoculation. D. congolensis was consistently cultured from the lesions even at 75 days post inoculation. Histopathologic examination of selected organs and tissues showed granulomatous caseous abscesses in the dermis, subcutaneous tissue and liver, edema of the dermis and widespread muscular degeneration and necrosis. D. congolensis organisms were associated with these lesions. No lesions or organisms were seen in the epidermis of the skin.

Research paper thumbnail of Hepatic Capillariasis in African Giant Rats (Cricetomys gambianus Waterhouse)

Journal of Wildlife Diseases, 1984

Research paper thumbnail of Pre-treatment with high dose vitamin A palmitate significantly enhances antibody response, reduces parasitaemia and improves survivability in experimental Trypanosoma brucei infection.

Research paper thumbnail of Effect of varied fermentation periods on the diabetogenic potential of toasted cassava granules

Plant foods for human nutrition (Dordrecht, Netherlands), 1999

The effects of exclusive gari diets prepared using varied fermentation periods on the fasting blo... more The effects of exclusive gari diets prepared using varied fermentation periods on the fasting blood glucose levels (FBGL) and glucose tolerance (GT) of rats were studied. Thirty growing male albino rats divided randomly into 5 groups of 6 rats each were used. The 5 groups were each fed gari diets fermented for 0, 24, 48, 72 hours; and a standard rat diet, respectively, for 8 weeks. Data on the total cyanogen content and % crude protein of the diets; FBGL, GT, body weight, water:feed consumption ratio and clinical observations of the rats were collected. Results showed that the total cyanogen content and % crude protein of the diets were depleted as fermentation periods increased. The FBGL of all the gari-fed rats were significantly elevated and their GT significantly impaired with a significant variation between the groups. The elevated FBGL and impaired GT which were found to increase with increase in fermentation period were strongly inversely correlated to the % crude protein con...

Research paper thumbnail of Investigations into the toxicity of the leaves of Erythrophleum guineense Don. in sheep

Research in veterinary science, 1980

An investigation was carried out on the toxicity of the leaves of Erythrophleum guineense Don. in... more An investigation was carried out on the toxicity of the leaves of Erythrophleum guineense Don. in sheep. Four groups of two animals each were fed 8, 2, 0.5 and 0.25 g/kg/day, respectively, of dried ground leaves of E guineense through a stomach tube. Two animals served as controls and received 8 g/kg/day of ground grass hay through a stomach tube. Animals which received 8 g/kg of E guineense died within 3 h; those which received 2 g/kg died within 18 h, while those which received 0.5 and 0.25 g/kg developed clinical signs after being fed for two to four days and died between two and 14 days. Clinical signs observed were coma and convulsions in animals which died within 18 h. Animals which died after several days of sickness had signs of depression, dyspnoea, groaning, trembling of hind limbs, strong heart beat and severe dysentery. Pathological changes observed post mortem were varied and occurred in a number of organs.

Research paper thumbnail of Toxic effects of the leaves of Erythrophleum africanum Harms in sheep

Bulletin of animal health and production in Africa. Bulletin des santé et production animales en Afrique, 1981

Research paper thumbnail of Ringworm caused by Trichophyton verrucosum in young goats: a case report

Bulletin of animal health and production in Africa. Bulletin des santé et production animales en Afrique, 1981

Research paper thumbnail of A survey of causes of organ condemnation in slaughtered cattle at Zaria, Nigeria

Bulletin of animal health and production in Africa. Bulletin des santé et production animales en Afrique, 1980

Research paper thumbnail of Incidence and importance of chronic mastitis in Nigeria goats

Bulletin of animal health and production in Africa. Bulletin des santé et production animales en Afrique, 1980

Research paper thumbnail of Clinical and epidemiological features of peste des petits ruminants in Sokoto Red goats

Revue d'élevage et de médecine vétérinaire des pays tropicaux, 1986

Research paper thumbnail of Ovine nasal adenopapilloma: incidence and clinicopathologic studies

American journal of veterinary research, 1978

Nasal adenopapillomas were observed in 9 Y'anKasa and 1 Y'anKasa-Suffolk crossbred sheep ... more Nasal adenopapillomas were observed in 9 Y'anKasa and 1 Y'anKasa-Suffolk crossbred sheep (8 females and 2 males) over a 20-month period. The neoplasms originated from the epithelium of the lateral mass of the ethmoid bone. Gross and histologic features and clinical signs were similar in all cases. Influence of sex, age, or genetics was not established.

Research paper thumbnail of Pathology of acute intestinal coccidiosis in young goats

Bulletin of animal health and production in Africa. Bulletin des santé et production animales en Afrique, 1979

Research paper thumbnail of Clinicopathologic implications of shortened fermentation periods in the production of toasted cassava granules (gari)

Plant Foods for Human Nutrition, 2003

Research paper thumbnail of Gastrointestinal globidiosis of Yankasa sheep in Nigeria

Veterinary Record, 1978

The first report of globidial gastroenteritis of sheep in Nigeria is presented. Clinical symptoms... more The first report of globidial gastroenteritis of sheep in Nigeria is presented. Clinical symptoms, gross and histopathological lesions associated with the disease in nine adult rams are described. The importance of differentiating the disease from intestinal coccidiosis in Yankasa sheep is stressed.

Research paper thumbnail of Intestinal leiomyoma in a cow

Veterinary Record, 1979

A 10-year-old white Fulani Bunaji cow with clinical signs of ruminal stasis and melaena, was euth... more A 10-year-old white Fulani Bunaji cow with clinical signs of ruminal stasis and melaena, was euthanised following discovery of a neoplasm in the spiral colon. Histopathological examination revealed a leiomyoma.

Research paper thumbnail of Microcephaly associated with kyphoscoliosis and cleft palate in a Yankassa lamb

Research paper thumbnail of Canine cyclopia

Research paper thumbnail of Enteritis associated with Eimeria leuckarti infection in donkeys

Research paper thumbnail of Acute toxicity and gastrointestinal irritant effect ofCroton penduliflorus seed oil in mice

Phytotherapy Research, 1988

... Acknowledgements This work was supported by the University of Nigeria Senate Research Grant N... more ... Acknowledgements This work was supported by the University of Nigeria Senate Research Grant No. 00422/81. The authors are grateful to Mr Udenyi of the Veterinary Anatomy department of this University. 0 Heyden & Son Limited, 1988 PHYTOTHERAPY RESEARCH, VOL. ...

Research paper thumbnail of DEGENERATIVE CARDIOMYOPATHY IN A CAPTIVE KANGAROO (Macropus giganteus)

Journal of Wildlife Diseases, 1978

Myocardial degeneration and necrosis in an adult female Australian kangaroo (Macropus giganteus) ... more Myocardial degeneration and necrosis in an adult female Australian kangaroo (Macropus giganteus) are described. The animal was housed in a zoo at Kano, Nigeria for approximately five years before death. This is believed to be the first reported case of degenerative cardiomyopathy in a captive marsupial in Nigeria.

Research paper thumbnail of PATHOLOGIC CHANGES IN LIZARDS (Agama agama) EXPERIMENTALLY INFECTED WITH Dermatophilus congolensis

Journal of Wildlife Diseases, 1980

Captive laboratory-held lizards (Agama agama) experimentally inoculated with Dermatophilus congol... more Captive laboratory-held lizards (Agama agama) experimentally inoculated with Dermatophilus congolensis by subcutaneous, intramuscular and intraperitoneal routes developed pyogranulomatous and necrotic lesions at and around the sites of inoculation. D. congolensis was consistently cultured from the lesions even at 75 days post inoculation. Histopathologic examination of selected organs and tissues showed granulomatous caseous abscesses in the dermis, subcutaneous tissue and liver, edema of the dermis and widespread muscular degeneration and necrosis. D. congolensis organisms were associated with these lesions. No lesions or organisms were seen in the epidermis of the skin.

Research paper thumbnail of Hepatic Capillariasis in African Giant Rats (Cricetomys gambianus Waterhouse)

Journal of Wildlife Diseases, 1984

Research paper thumbnail of The Leucocytic and Parasitaemic Profiles and Immune Response of Rats Treated with Retinyl Palmitate before Infection with Trypanosoma brucei

Journal of Comparative Pathology, 2003

Research paper thumbnail of Fundamentals of Systemic Veterinary Pathology Volume 2

Fundamentals of Systemic Veterinary Pathology is an undergraduate course book on the pathology of... more Fundamentals of Systemic Veterinary Pathology is an undergraduate course book on the pathology of the body systems of animals, which was developed in response to the need and yearnings for readily available books and study materials for undergraduate veterinary students. The contents of “Fundamentals of Systemic Veterinary Pathology” extensively cover the systemic veterinary pathology syllabus of standard paraclinical veterinary curriculum/programme and even more. The widely pedagogically recommended integrated format for content selection was followed, such that the already acquired basic knowledge of veterinary anatomy, physiology and biochemistry of each body system was briefly reviewed in the “Introduction” to each system and carefully integrated into the discussion of lesions in order to establish a link and lay a solid foundation for the acquisition of the new knowledge of the pathology of the body systems that was presented. The diseases associated with the lesions discussed in each of the body systems and the possible clinical implications of the lesions were also briefly reviewed in order to further integrate the study of the pathology of the body systems with that of specific diseases (special pathology) and clinical medicine. Volume 1 of Fundamentals of Systemic Veterinary Pathology covers the pathology of the integument, muscle, haematopoietic system, nervous system and organs of special sense (eye and ear), while Volume 2 contains presentations on the pathology of the circulatory, respiratory, digestive, urinary and reproductive systems. In both volumes, pathologic changes were described in simple language that demystified the wrong belief among students that pathology is difficult to study. Numerous photographs and illustrations were inserted where appropriate in order to bring to life the gross and microscopic appearance of the lesions discussed in the body systems. Beyond describing lesions, the pathogenesis and pathologic basis for the lesions were clearly presented in order to enhance in-depth understanding of the disease process; this was considered important because knowledge of pathology is needed beyond the veterinary school, in fact, it is much more important in field veterinary practice after graduation.