Canan Tikiz - Academia.edu (original) (raw)

Papers by Canan Tikiz

Archives of Rheumatology

Objectives: The purpose of the study was to contribute further to this debated topic by investiga... more Objectives: The purpose of the study was to contribute further to this debated topic by investigating the correlation of magnetic resonance imaging (MRI) findings with the clinical picture in lumbar spondylosis patients. Patients and methods: This multicenter retrospective study (as part of the epidemiological project of the TLAR-OASG [Turkish League Against Rheumatism-Osteoarthritis Study Group]) included 514 patients (101 males, 413 females; mean age: 63.6±10.8 years; range, 40 to 85 years) who were diagnosed as lumbar spondylosis by clinical examination and direct X-ray between December 2016 and June 2018. Demographic characteristics of patients, Visual Analog Scale for pain, presence of radiating pain, Roland-Morris disability questionnaire, straight leg raise test, deep tendon reflexes, neurogenic intermittent claudication symptoms, any decrease of muscle strength, and abnormality of sensation were recorded. Lumbar MRI findings of the patients were recorded as positive or negat...

Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir, 2019

OBJECTIVE Peripheral neuropathy is an important potential side effect of statin use. This study w... more OBJECTIVE Peripheral neuropathy is an important potential side effect of statin use. This study was an investigation of the incidence of peripheral neuropathy in patients taking atorvastatin or rosuvastatin for hypercholesterolemia and the relationship to the dose and duration of the treatment. METHODS In all, 50 patients using a statin treatment and 50 healthy controls matched for age and gender who had never taken a statin were included in the study. Polyneuropathy was assessed with a neurological examination and electroneuromyography (ENMG). RESULTS While no polyneuropathy was detected in the control group, polyneuropathy was seen in 33 (66%) of the patients in the statin group (p<0.01). There was no significant difference between the 2 statin groups in the results of the neurological examination or the ENMG findings regarding the incidence of polyneuropathy (p=0.288 and p=0.720, respectively). Neuropathy was observed in a neurological examination performed within the first ye...

Turkish Journal of …, 1999

Geriatri (Turkısh Journal Of Gerıatrıcs).

Journal of Rehabilitation Medicine, 2006

Objective: To investigate the effects of regular submaximal exercise on quality of life, exercise... more Objective: To investigate the effects of regular submaximal exercise on quality of life, exercise capacity and pulmonary function in asthmatic children. Patients and methods: Sixty-two children with mild Á /moderate asthma (mean age 10.4 (SD 2.1) years) were randomly allocated into exercise and control groups. The exercise group underwent a moderately intensive basketball training program for 8 weeks. A home respiratory exercise program was advised to both groups. Pediatric Asthma Quality of Life Questionnaire (PAQLQ) was used for the evaluation of activity limitation, symptoms and emotional functions. Exercise capacity was evaluated through the physical work capacity (PWC 170 test) on a cycle ergometer and 6-minute walk test. Spirometric tests were also performed and medication and symptom scores were recorded. Results: Although PAQLQ scores improved in both groups, the improvement in the exercise group was significantly higher. The exercise group performed better in the PWC 170 and 6-minute walk tests, whereas no improvement was detected in the control group at the end of the trial. Medication scores improved in both groups, but symptom scores improved only in the exercise group. No significant changes were detected in pulmonary function in either group, except for peak expiratory flow values in the exercise group. Conclusion: Eight weeks of regular submaximal exercise has beneficial effects on quality of life and exercise capacity in children with asthma. Submaximal basketball training is an effective alternative exercise program for asthmatic children.

World Journal of Pediatrics

Türkiye Fiziksel Tıp ve Rehabilitasyon Dergisi, 2005

Romatoloji ve Tıbbi Rehabilitasyon Dergisi, 2001

Objectives: To evaluate whether g-glutamyl transferase can be used as a new novel bone resorption... more Objectives: To evaluate whether g-glutamyl transferase can be used as a new novel bone resorption marker in postmenopusal osteoporotic subjects. Design and methods: 156 postmenopausal subjects were divided into three groups according to their lumbar spine T-score measured by dual-energy X-ray absorptiometry as normal, (control group, n=56), osteopenic (n=50) and osteoporotic (n=50). Deoxypyridinoline and g-glutamyl transferase from urine samples and osteocalcin and bone specific alkaline phosphates from blood samples were assessed. Results: Osteocalcin and bone specific alkaline phosphates levels were increased in osteoporotic group (p 0.05). No significant correlation was found between urinary g-glutamyl transferase and deoxypyridinoline, bone specific alkaline phosphates and osteocalcin (p>0.05). Urinary g-glutamyl transferase levels showed no significant correlation with neither bone mineral density nor T scores in all subjects (r= 0.058 p= 0.625, r=-0.074 p=0.533 respectively...

1Gürbüz BÜYÜKYAZI 2Canan TIKIZ 3Cevval ULMAN 4Hakan TIKIZ 3Bekir Sami UYANIK 1Celal Bayar Ünivers... more 1Gürbüz BÜYÜKYAZI 2Canan TIKIZ 3Cevval ULMAN 4Hakan TIKIZ 3Bekir Sami UYANIK 1Celal Bayar Üniversitesi Beden Eğitimi ve Spor Yüksekokulu , Manisa 2Celal Bayar Üniversitesi Tıp Fakültesi, Fizik Tedavi Rehabilitasyon2, Biyokimya3, Kardiyoloji4 Anabilim Dalları, Manisa Anahtar Kelimeler: kan lipidleri, homosistein, Vitamin B12, folik asit, yürüyüş

Turkish Journal of Physical Medicine and Rehabilitation, 2020

Coronavirus disease 2019 (COVID-19) is a contagious infection disease, which may cause respirator... more Coronavirus disease 2019 (COVID-19) is a contagious infection disease, which may cause respiratory, physical, psychological, and generalized systemic dysfunction. The severity of disease ranges from an asymptomatic infection or mild illness to mild or severe pneumonia with respiratory failure and/or death. COVID-19 dramatically affects the pulmonary system. There is a lack of knowledge about the long-term outcomes of the disease and the possible sequelae and rehabilitation. This clinical practice guideline includes pulmonary rehabilitation (PR) recommendations for adult COVID-19 patients and has been developed in the light of the guidelines on the diagnosis and treatment of COVID-19 provided by the World Health Organization and Republic of Turkey, Ministry of Health, recently published scientific literature, and PR recommendations for COVID-19 regarding basic principles of PR. In this guideline, the contagiousness of COVID-19, recommendations on limited contact of patient with healthcare providers, and the evidence about possible benefits of PR were taken into consideration.

Turkiye Klinikleri Journal of Internal Medical Sciences, 2006

Turkiye Klinikleri Journal of Physical Medicine Rehabilitation Special Topics, 2012

Turkiye Klinikleri Fiziksel Tıp Ve Rehabilitasyon Ozel Dergisi, 2013

Journal of Urology, 2005

Purpose: We explored the effects of early and late application of botulinum-A toxin (BTX-A) on re... more Purpose: We explored the effects of early and late application of botulinum-A toxin (BTX-A) on reservoir function and histological bladder changes in spinal cord injured rats. Materials and Methods: The study was done in 30 Sprague-Dawley rats randomly allocated into 5 groups. Group 1 of 6 rats underwent sham operation only. Group 2 of 6 rats underwent spinal cord transection. Group 3 of 6 rats underwent spinal cord transection followed by BTX-A application into the detrusor muscle 7 days later. Group 4 of 6 rats underwent spinal cord transection, followed by BTX-A application into the detrusor muscle 28 days later. Group 5 of 6 rats underwent spinal cord transection followed by saline injection into the detrusor muscle after 28 days. Spinal cord injury was created by transecting the cord at the T9 to T10 level. All rats underwent cystometric examination initially and on day 42 before sacrifice. The bladders were removed and examined histologically for fibrosis and hyperplasia. Results: On cystometric examination BTX-A caused an improvement in baseline pressure, and the frequency and amplitude of uninhibited detrusor contractions (p Ͻ0.001). No significant differences were observed in maximal bladder capacity or urethral opening pressure (p Ͼ0.05). Histologically BTX-A led to decreased fibrosis and hyperplasia (p Ͻ0.001). No significant differences were found between histological or cystometric among the groups with respect to receiving BTX-A in the early and late periods (p Ͼ0.05). Conclusions: BTX-A has a functional and histological healing effect on detrusor hyperreflexia subsequent to spinal cord injury in rats. Although administering BTX-A in the early period had better quantifiable functional and histological outcomes compared to the late period, the difference was not statistically significant.

Allergologia et Immunopathologia, 2011

Background: The pathogenesis of asthma involves both airway inflammation and an oxidant/antioxida... more Background: The pathogenesis of asthma involves both airway inflammation and an oxidant/antioxidant imbalance. It is demonstrated in asthmatic adults that exercise programmes improve lung function, a mechanism yet to be elucidated. The purpose of this study was to investigate the possible beneficial effects of physical exercise on antioxidant status in asthmatic children which may lead to ameliorated lung function. Methods: The study enrolled thirteen control and thirty asthmatic children. The asthmatic group was subdivided into two: the first group receiving only pharmacological treatment (n = 15) and the second receiving pharmacological treatment with exercise programme (n = 15) for 8 weeks. Blood samples were drawn from the subjects before and after treatment periods. As oxidant stress markers blood levels of malondialdehyde (MDA) and total nitric oxide (NO), and as antioxidant status, glutathione peroxidase (GSH-Px) and superoxide dismutase (SOD) enzyme activities were assessed. Results: Before any treatment was initiated, MDA and NO levels in the asthmatic group were significantly higher than the controls (3.40 ± 0.96 nmol/ml vs 2.46 ± 0.58 nmol/ml, and 12.53 ± 2.10 vs 9.40 ± 1.39 micromol/L, respectively). Both SOD (p = 0.0001) and GSH-Px (p = 0.023) activities were significantly lower in the asthmatic group. Pharmacological treatment and exercise programme together significantly improved lung performance and decreased the levels of oxidant stress markers, in concordance with a significantly increase in antioxidant enzyme activity measures when compared to the pharmacological treatment. Conclusion: Structured exercise programme in asthmatic children resulted in better lung function, which may be attributed to its effect on antioxidant status.

Archives of Rheumatology, 2016

Annals of Geriatric Medicine and Research

Background: Dysphagia is a geriatric syndrome. Changes in the whole body that occur with aging al... more Background: Dysphagia is a geriatric syndrome. Changes in the whole body that occur with aging also affect swallowing functions and cause presbyphagia. This condition may progress to oropharyngeal and/or esophageal dysphagia in the presence of secondary causes that increase in incidence with aging. However, no study has been published that provides recommendations for use in clinical practice that addresses in detail all aspects of the management of dysphagia in geriatric individuals. This study aimed to answer almost all potential questions and problems in the management of geriatric dysphagia in clinical practice. Methods: A multidisciplinary team created this recommendation guide using the seven-step and three-round modified Delphi method via e-mail. The study included 39 experts from 29 centers in 14 cities.Results: Based on the 5W and 1H method, we developed 216 detailed recommendations for older adults from the perspective of different disciplines dealing with older people. Co...

Objective: To evaluate the effects of regular exer-cise on asthma symptom score, quality of life ... more Objective: To evaluate the effects of regular exer-cise on asthma symptom score, quality of life and pulmonary function in asthmatic children. Materials and Methods: Thirty children with newly diagnosed mild-moderate asthma (mean age 9.8 ± 1.78 years) were randomly allocated into exer-cise group (group 1) and control group (group 2). Both groups received inhaled fluticasone and mon-telukast treatment. Children in the exercise group were also included in an exercise training program. The program consisted of condition bicycle for one hour two times a week for 8 weeks. Pediatric Asth-ma Quality of Life Questionnaire (PAQLQ), a dise-ase spesific quality of life questionnaire, and