Todd Canada - Academia.edu (original) (raw)

Papers by Todd Canada

BackgroundSerum prealbumin has long been used as a marker of nutritional status. However, prealbu... more BackgroundSerum prealbumin has long been used as a marker of nutritional status. However, prealbumin is a negative acute phase reactant influenced by several non-nutritional-related factors including surgery, infection, and cancer. An increasing prealbumin has been correlated with a positive nitrogen balance in general surgery patients receiving parenteral nutrition (PN) with 88% specificity and 70% sensitivity. To date, no trial has evaluated the effect of concurrent cancer and surgery on the value of prealbumin in predicting nitrogen balance.MethodsThis study is a concurrent retrospective design of post-operative patients (≥ 19 years of age) identified by the nutrition support service who received PN for ≥ 5 days, had a baseline and follow-up serum prealbumin and C-reactive Protein (CRP) measured, as well as a 24-hour urinary urea nitrogen (UUN) performed between days 5-10 of PN. Exclusion criteria include anuric renal failure, Child-Pugh Class C liver failure, pregnancy, and cort...

Hospital Pharmacy, Mar 16, 2023

Staying current with the literature is an essential requirement for the informed pharmacist who m... more Staying current with the literature is an essential requirement for the informed pharmacist who maintains an evidence-based clinical practice. This requirement has become more challenging to fulfill as the practice model of the traditional full-time pharmacy nutrition support specialist has changed at many institutions. Many former specialists now practice within an integrated model whereby the clinical pharmacist provides pharmacotherapy services along with nutrition support responsibilities. As a result of this change, clinicians are responsible for staying current within numerous therapeutic areas that interface with clinical practice including nutrition support. Because nutrition support therapy is integrated with many divergent specialized fields, it is an extremely daunting task for one individual to screen the abundant amount of available journals each month to seek out those clinical studies, position papers, or clinical guidelines that may enhance or change clinical practice. The intent of this article is to provide an updated source of new pertinent literature published in 2016. Methods To assist pharmacy clinicians engaged in nutrition support in staying current with the most pertinent literature, the principal author participant of this article (R.N.D.) invited 7 additional clinical pharmacists to participate in this project. The potential author participants were invited based on the principal author's perception of their active involvement in the field as supported by their educational, research, or professional committee involvement in pharmacy nutrition support, particularly in the American Society for Parenteral and Enteral Nutrition (ASPEN). All authors are board certified. Four author participants are board certified solely in pharmacy nutrition support, whereas others are certified in areas whereby nutrition support is part of their practice or have 720313H PXXXX10.

Hospital Pharmacy, Jun 17, 2020

Staying current with the literature is an essential requirement for the informed pharmacist who m... more Staying current with the literature is an essential requirement for the informed pharmacist who maintains an evidence-based clinical practice. This requirement has become more challenging to fulfill as the practice model of the traditional full-time pharmacy nutrition support specialist has changed at many institutions. Many former specialists now practice within an integrated model whereby the clinical pharmacist provides pharmacotherapy services along with nutrition support responsibilities. As a result of this change, clinicians are responsible for staying current within numerous therapeutic areas that interface with clinical practice including nutrition support. Because nutrition support therapy is integrated with many divergent specialized fields, it is an extremely daunting task for one individual to screen the abundant amount of available journals each month to seek out those clinical studies, position papers, or clinical guidelines that may enhance or change clinical practice. The intent of this article is to provide an updated source of new pertinent literature published in 2016. Methods To assist pharmacy clinicians engaged in nutrition support in staying current with the most pertinent literature, the principal author participant of this article (R.N.D.) invited 7 additional clinical pharmacists to participate in this project. The potential author participants were invited based on the principal author's perception of their active involvement in the field as supported by their educational, research, or professional committee involvement in pharmacy nutrition support, particularly in the American Society for Parenteral and Enteral Nutrition (ASPEN). All authors are board certified. Four author participants are board certified solely in pharmacy nutrition support, whereas others are certified in areas whereby nutrition support is part of their practice or have 720313H PXXXX10.

Hospital Pharmacy, Jun 4, 2022

Staying current with the literature is an essential requirement for the informed pharmacist who m... more Staying current with the literature is an essential requirement for the informed pharmacist who maintains an evidence-based clinical practice. This requirement has become more challenging to fulfill as the practice model of the traditional full-time pharmacy nutrition support specialist has changed at many institutions. Many former specialists now practice within an integrated model whereby the clinical pharmacist provides pharmacotherapy services along with nutrition support responsibilities. As a result of this change, clinicians are responsible for staying current within numerous therapeutic areas that interface with clinical practice including nutrition support. Because nutrition support therapy is integrated with many divergent specialized fields, it is an extremely daunting task for one individual to screen the abundant amount of available journals each month to seek out those clinical studies, position papers, or clinical guidelines that may enhance or change clinical practice. The intent of this article is to provide an updated source of new pertinent literature published in 2016. Methods To assist pharmacy clinicians engaged in nutrition support in staying current with the most pertinent literature, the principal author participant of this article (R.N.D.) invited 7 additional clinical pharmacists to participate in this project. The potential author participants were invited based on the principal author's perception of their active involvement in the field as supported by their educational, research, or professional committee involvement in pharmacy nutrition support, particularly in the American Society for Parenteral and Enteral Nutrition (ASPEN). All authors are board certified. Four author participants are board certified solely in pharmacy nutrition support, whereas others are certified in areas whereby nutrition support is part of their practice or have 720313H PXXXX10.

Hospital Pharmacy, May 30, 2018

Staying current with the literature is an essential requirement for maintaining an evidence-based... more Staying current with the literature is an essential requirement for maintaining an evidence-based clinical practice. 1 Staying current, within a specialized field such as nutrition support, has become even more challenging as many institutions have adopted an integrated practice model whereby the clinical pharmacist provides pharmacotherapy services in addition to specialized services. Clinicians are held accountable for staying current within numerous therapeutic areas that interface with their clinical practice. Because nutrition support therapy is integrated within differing clinical practices, it is a daunting task for one individual to screen the abundance of information from numerous journals each month to seek out those clinical studies, position papers, or clinical guidelines that may enhance or change current clinical practice in pharmacy nutrition support. Over the past few years, 2-4 as clinicians who practice fulltime or part-time in pharmacy nutrition support, it has been our intent to provide a yearly source of new literature important to pharmacy nutrition support practice. This article identifies and discusses significant articles that were published in 2017. Methods To assist pharmacy clinicians engaged in nutrition support in staying current with the most pertinent literature, the principal author participant of this articles (R.N.D.) invited 7 clinical pharmacists to participate in this project. The potential author participants were invited based on the principal author's perception of their active involvement in the field as supported by their educational, research, or professional committee involvement in pharmacy nutrition support, particularly in the American Society for Parenteral and Enteral Nutrition (ASPEN). All authors are board certified. Four author participants are board certified solely in pharmacy nutrition support, whereas others are certified in areas whereby nutrition support is part of their practice or 779006H PXXXX10.

Hospital Pharmacy, Jun 1, 2017

Staying current with the literature is an essential requirement for the informed pharmacist who m... more Staying current with the literature is an essential requirement for the informed pharmacist who maintains an evidence-based clinical practice. This requirement has become more challenging to fulfill as the practice model of the traditional full-time pharmacy nutrition support specialist has changed at many institutions. Many former specialists now practice within an integrated model whereby the clinical pharmacist provides pharmacotherapy services along with nutrition support responsibilities. As a result of this change, clinicians are responsible for staying current within numerous therapeutic areas that interface with clinical practice including nutrition support. Because nutrition support therapy is integrated with many divergent specialized fields, it is an extremely daunting task for one individual to screen the abundant amount of available journals each month to seek out those clinical studies, position papers, or clinical guidelines that may enhance or change clinical practice. The intent of this article is to provide an updated source of new pertinent literature published in 2016. Methods To assist pharmacy clinicians engaged in nutrition support in staying current with the most pertinent literature, the principal author participant of this article (R.N.D.) invited 7 additional clinical pharmacists to participate in this project. The potential author participants were invited based on the principal author's perception of their active involvement in the field as supported by their educational, research, or professional committee involvement in pharmacy nutrition support, particularly in the American Society for Parenteral and Enteral Nutrition (ASPEN). All authors are board certified. Four author participants are board certified solely in pharmacy nutrition support, whereas others are certified in areas whereby nutrition support is part of their practice or have 720313H PXXXX10.

Hospital Pharmacy, May 25, 2019

Staying current with the literature is an essential requirement for the informed pharmacist who m... more Staying current with the literature is an essential requirement for the informed pharmacist who maintains an evidence-based clinical practice. This requirement has become more challenging to fulfill as the practice model of the traditional full-time pharmacy nutrition support specialist has changed at many institutions. Many former specialists now practice within an integrated model whereby the clinical pharmacist provides pharmacotherapy services along with nutrition support responsibilities. As a result of this change, clinicians are responsible for staying current within numerous therapeutic areas that interface with clinical practice including nutrition support. Because nutrition support therapy is integrated with many divergent specialized fields, it is an extremely daunting task for one individual to screen the abundant amount of available journals each month to seek out those clinical studies, position papers, or clinical guidelines that may enhance or change clinical practice. The intent of this article is to provide an updated source of new pertinent literature published in 2016. Methods To assist pharmacy clinicians engaged in nutrition support in staying current with the most pertinent literature, the principal author participant of this article (R.N.D.) invited 7 additional clinical pharmacists to participate in this project. The potential author participants were invited based on the principal author's perception of their active involvement in the field as supported by their educational, research, or professional committee involvement in pharmacy nutrition support, particularly in the American Society for Parenteral and Enteral Nutrition (ASPEN). All authors are board certified. Four author participants are board certified solely in pharmacy nutrition support, whereas others are certified in areas whereby nutrition support is part of their practice or have 720313H PXXXX10.

Hospital Pharmacy, 2021

Purpose: The purpose of this article is to assist the pharmacist engaged in nutrition support the... more Purpose: The purpose of this article is to assist the pharmacist engaged in nutrition support therapy in staying current with pertinent literature. Methods: Several clinical pharmacists engaged in nutrition support therapy compiled a list of articles published in 2020 considered important to their clinical practice. The citation list was compiled into a single spreadsheet where the author participants were asked to assess whether the article was considered important to nutrition support pharmacy practice. A culled list of publications was then identified whereby at least 5 out of the 8 author participants considered the paper to be important. Guideline and consensus papers from professional organizations, important to practice but not ranked, were also included. Results: A total of 169 articles were identified; 5 from the primary literature were voted by the group to be of high importance. An additional 17 guidelines, position, recommendation, or consensus papers were also identifie...

The American Journal of Clinical Nutrition, 2017

Nutrition in Clinical Practice, 2006

Background: Chronic obstructive pulmonary disease (COPD), the fifth‐leading cause of death worldw... more Background: Chronic obstructive pulmonary disease (COPD), the fifth‐leading cause of death worldwide, is characterized by chronic inflammation. However, no available agent can effectively cure this inflammation. A dietary supplement containing ω‐3 polyunsaturated fatty acids (PUFAs) has anti‐inflammatory effects. In this study, we hypothesized that nutrition support with ω‐3 PUFA‐rich diets may be useful for treating COPD, and we compared the clinical features and inflammatory mediator levels between the COPD patients who received an ω‐3 PUFA‐rich supplement and those who received a nonrich supplement. Methods: Sixty‐four COPD patients received 400 kcal per day of an ω‐3 PUFA‐rich supplement (ω‐3 group) or an ω‐3 PUFA‐nonrich supplement (ω‐6 group) for 2 years. We prospectively investigated the clinical features of these patients and measured the levels of inflammatory mediators. Results: In 6‐minute walk testing, the dyspnea Borg scale and decrease of arterial oxygen saturation mea...

American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2017

The American Journal of Medicine, 2017

We read with interest the findings of Tsapepas et al 1 associating hyponatremia with high-dose tr... more We read with interest the findings of Tsapepas et al 1 associating hyponatremia with high-dose trimethoprim (TMP) exposure. Tsapepas et al 1 assert that high doses of trimethoprim-sulfamethoxazole (TMP-SMX) have a higher incidence of hyponatremia in patients with pneumonia. However, there is a confounder regarding the dosage form, particularly the intravenous (IV) formulation, affecting the incidence of hyponatremia. Trimethoprim is least likely to precipitate in the acidic environment of diluents containing dextrose, in which 5% dextrose is the preferred diluent. 2,3 Given the mean dose of TMP and weight of patients from the article and a 5% dextrose diluent, each patient would have received a TMP-SMX dose with approximately 1 L of 5% dextrose daily. 1,3 The accumulation of excess free water from the 5% dextrose may have contributed to the higher incidence of hyponatremia with respect to total treatment dose and duration. It should be noted that TMP-SMX does have variable compatibility with 0.9% sodium chloride, along with other sodium-containing combinations of diluents that can be used as part of the IV formulation. 2 A characterization of the IV TMP-SMX formulations used in this study could result in the development of hyponatremia, and using 0.9% sodium chloride as the diluent would further strengthen the higher incidence of hyponatremia in patients given high doses of TMP-SMX.

Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition, 2006

To compare the effects of a low-carbohydrate diet and a conventional (fat- and calorie-restricted... more To compare the effects of a low-carbohydrate diet and a conventional (fat- and calorie-restricted) diet on lipoprotein subfractions and inflammation in severely obese subjects. We compared changes in lipoprotein subfractions and C-reactive protein levels in 78 severely obese subjects, including 86% with either diabetes or metabolic syndrome, who were randomly assigned to either a low-carbohydrate or conventional diet for 6 months. Subjects on a low-carbohydrate diet experienced a greater decrease in large very low-density lipoprotein (VLDL) levels (difference =-0.26 mg/dL, p = .03) but more frequently developed detectable chylomicrons (44% vs 22%, p = .04). Both diet groups experienced similar decreases in the number of low-density lipoprotein (LDL) particles (difference = -30 nmol/L, p = .74) and increases in large high-density lipoprotein (HDL) concentrations (difference = 0.70 mg/dL, p = .63). Overall, C-reactive protein levels decreased modestly in both diet groups. However, pat...

Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition, 2006

The aim of this study was to assess the efficacy of preoperative and postoperative treatment with... more The aim of this study was to assess the efficacy of preoperative and postoperative treatment with ω-3 polyunsaturated fatty acids (PUFAs) in preventing the occurrence of atrial fibrillation (AF) after coronary artery bypass graft surgery (CABG). Postoperative AF is a common complication of CABG. There is growing clinical evidence that PUFAs have cardiac antiarrhythmic effects. A total of 160 patients were prospectively randomized to a control group (81 patients, 13 female, 64.9 ± 9.1 years) or PUFAs 2 g/day (79 patients, 11 female, 66.2 ± 8.0 years) for at least 5 days before elective CABG and until the day of discharge from the hospital. The primary end point was the development of AF in the postoperative period. The secondary end point was the hospital length of stay after surgery. All end points were independently adjudicated by 2 cardiologists blinded to treatment assignment. The clinical and surgical characteristics of the patients in the 2 groups were similar. Postoperative AF...

Hospital Pharmacy, 2016

Purpose To assist the pharmacy clinician engaged in nutrition support in staying current with the... more Purpose To assist the pharmacy clinician engaged in nutrition support in staying current with the most pertinent literature. Methods Several experienced board-certified clinical pharmacists engaged in nutrition support therapy compiled a list of articles published in 2014 and 2015 that they considered to be important to their practice. Only those articles available in print format were considered for potential inclusion. Articles available only in preprint electronic format were not evaluated. The citation list was compiled into a single spreadsheet where the author participants were asked to ascertain whether they considered the paper important to nutrition support pharmacy practice. A culled list of publications was then identified whereby the majority of author participants (at least 5 out of 8) considered the paper to be important. Results A total of 108 articles were identified; 36 of which were considered to be of high importance. An important guideline article published in ea...

Acute Care of the Cancer Patient, 2005

Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition, 2003

... Ginger Langley, PharmD; Todd Canada, PharmD, BCNSP; and Lora Day, MS, RD, CNSD The University... more ... Ginger Langley, PharmD; Todd Canada, PharmD, BCNSP; and Lora Day, MS, RD, CNSD The University of Texas MD Anderson Cancer Center, Division of Pharmacy, Houston; and Department of Dietetics, Parkland Health & Hospital System, Dallas, Texas Metabolic Acidosis ...

Journal of the American Dietetic Association, 1998

Malnutrition is a common problem in cancer patients and, if untreated, can lead to cancer cachexi... more Malnutrition is a common problem in cancer patients and, if untreated, can lead to cancer cachexia and poor response to therapies. Subjective Global Assessment (SGA) has been shown to be valid and comparable with objective measures such as the Prognostic Nutritional Index (PNI) in general surgery patients. The purpose of this study was to determine the reproducibility of SGA ratings

BackgroundSerum prealbumin has long been used as a marker of nutritional status. However, prealbu... more BackgroundSerum prealbumin has long been used as a marker of nutritional status. However, prealbumin is a negative acute phase reactant influenced by several non-nutritional-related factors including surgery, infection, and cancer. An increasing prealbumin has been correlated with a positive nitrogen balance in general surgery patients receiving parenteral nutrition (PN) with 88% specificity and 70% sensitivity. To date, no trial has evaluated the effect of concurrent cancer and surgery on the value of prealbumin in predicting nitrogen balance.MethodsThis study is a concurrent retrospective design of post-operative patients (≥ 19 years of age) identified by the nutrition support service who received PN for ≥ 5 days, had a baseline and follow-up serum prealbumin and C-reactive Protein (CRP) measured, as well as a 24-hour urinary urea nitrogen (UUN) performed between days 5-10 of PN. Exclusion criteria include anuric renal failure, Child-Pugh Class C liver failure, pregnancy, and cort...

Hospital Pharmacy, Mar 16, 2023

Staying current with the literature is an essential requirement for the informed pharmacist who m... more Staying current with the literature is an essential requirement for the informed pharmacist who maintains an evidence-based clinical practice. This requirement has become more challenging to fulfill as the practice model of the traditional full-time pharmacy nutrition support specialist has changed at many institutions. Many former specialists now practice within an integrated model whereby the clinical pharmacist provides pharmacotherapy services along with nutrition support responsibilities. As a result of this change, clinicians are responsible for staying current within numerous therapeutic areas that interface with clinical practice including nutrition support. Because nutrition support therapy is integrated with many divergent specialized fields, it is an extremely daunting task for one individual to screen the abundant amount of available journals each month to seek out those clinical studies, position papers, or clinical guidelines that may enhance or change clinical practice. The intent of this article is to provide an updated source of new pertinent literature published in 2016. Methods To assist pharmacy clinicians engaged in nutrition support in staying current with the most pertinent literature, the principal author participant of this article (R.N.D.) invited 7 additional clinical pharmacists to participate in this project. The potential author participants were invited based on the principal author's perception of their active involvement in the field as supported by their educational, research, or professional committee involvement in pharmacy nutrition support, particularly in the American Society for Parenteral and Enteral Nutrition (ASPEN). All authors are board certified. Four author participants are board certified solely in pharmacy nutrition support, whereas others are certified in areas whereby nutrition support is part of their practice or have 720313H PXXXX10.

Hospital Pharmacy, Jun 17, 2020

Staying current with the literature is an essential requirement for the informed pharmacist who m... more Staying current with the literature is an essential requirement for the informed pharmacist who maintains an evidence-based clinical practice. This requirement has become more challenging to fulfill as the practice model of the traditional full-time pharmacy nutrition support specialist has changed at many institutions. Many former specialists now practice within an integrated model whereby the clinical pharmacist provides pharmacotherapy services along with nutrition support responsibilities. As a result of this change, clinicians are responsible for staying current within numerous therapeutic areas that interface with clinical practice including nutrition support. Because nutrition support therapy is integrated with many divergent specialized fields, it is an extremely daunting task for one individual to screen the abundant amount of available journals each month to seek out those clinical studies, position papers, or clinical guidelines that may enhance or change clinical practice. The intent of this article is to provide an updated source of new pertinent literature published in 2016. Methods To assist pharmacy clinicians engaged in nutrition support in staying current with the most pertinent literature, the principal author participant of this article (R.N.D.) invited 7 additional clinical pharmacists to participate in this project. The potential author participants were invited based on the principal author's perception of their active involvement in the field as supported by their educational, research, or professional committee involvement in pharmacy nutrition support, particularly in the American Society for Parenteral and Enteral Nutrition (ASPEN). All authors are board certified. Four author participants are board certified solely in pharmacy nutrition support, whereas others are certified in areas whereby nutrition support is part of their practice or have 720313H PXXXX10.

Hospital Pharmacy, Jun 4, 2022

Staying current with the literature is an essential requirement for the informed pharmacist who m... more Staying current with the literature is an essential requirement for the informed pharmacist who maintains an evidence-based clinical practice. This requirement has become more challenging to fulfill as the practice model of the traditional full-time pharmacy nutrition support specialist has changed at many institutions. Many former specialists now practice within an integrated model whereby the clinical pharmacist provides pharmacotherapy services along with nutrition support responsibilities. As a result of this change, clinicians are responsible for staying current within numerous therapeutic areas that interface with clinical practice including nutrition support. Because nutrition support therapy is integrated with many divergent specialized fields, it is an extremely daunting task for one individual to screen the abundant amount of available journals each month to seek out those clinical studies, position papers, or clinical guidelines that may enhance or change clinical practice. The intent of this article is to provide an updated source of new pertinent literature published in 2016. Methods To assist pharmacy clinicians engaged in nutrition support in staying current with the most pertinent literature, the principal author participant of this article (R.N.D.) invited 7 additional clinical pharmacists to participate in this project. The potential author participants were invited based on the principal author's perception of their active involvement in the field as supported by their educational, research, or professional committee involvement in pharmacy nutrition support, particularly in the American Society for Parenteral and Enteral Nutrition (ASPEN). All authors are board certified. Four author participants are board certified solely in pharmacy nutrition support, whereas others are certified in areas whereby nutrition support is part of their practice or have 720313H PXXXX10.

Hospital Pharmacy, May 30, 2018

Staying current with the literature is an essential requirement for maintaining an evidence-based... more Staying current with the literature is an essential requirement for maintaining an evidence-based clinical practice. 1 Staying current, within a specialized field such as nutrition support, has become even more challenging as many institutions have adopted an integrated practice model whereby the clinical pharmacist provides pharmacotherapy services in addition to specialized services. Clinicians are held accountable for staying current within numerous therapeutic areas that interface with their clinical practice. Because nutrition support therapy is integrated within differing clinical practices, it is a daunting task for one individual to screen the abundance of information from numerous journals each month to seek out those clinical studies, position papers, or clinical guidelines that may enhance or change current clinical practice in pharmacy nutrition support. Over the past few years, 2-4 as clinicians who practice fulltime or part-time in pharmacy nutrition support, it has been our intent to provide a yearly source of new literature important to pharmacy nutrition support practice. This article identifies and discusses significant articles that were published in 2017. Methods To assist pharmacy clinicians engaged in nutrition support in staying current with the most pertinent literature, the principal author participant of this articles (R.N.D.) invited 7 clinical pharmacists to participate in this project. The potential author participants were invited based on the principal author's perception of their active involvement in the field as supported by their educational, research, or professional committee involvement in pharmacy nutrition support, particularly in the American Society for Parenteral and Enteral Nutrition (ASPEN). All authors are board certified. Four author participants are board certified solely in pharmacy nutrition support, whereas others are certified in areas whereby nutrition support is part of their practice or 779006H PXXXX10.

Hospital Pharmacy, Jun 1, 2017

Staying current with the literature is an essential requirement for the informed pharmacist who m... more Staying current with the literature is an essential requirement for the informed pharmacist who maintains an evidence-based clinical practice. This requirement has become more challenging to fulfill as the practice model of the traditional full-time pharmacy nutrition support specialist has changed at many institutions. Many former specialists now practice within an integrated model whereby the clinical pharmacist provides pharmacotherapy services along with nutrition support responsibilities. As a result of this change, clinicians are responsible for staying current within numerous therapeutic areas that interface with clinical practice including nutrition support. Because nutrition support therapy is integrated with many divergent specialized fields, it is an extremely daunting task for one individual to screen the abundant amount of available journals each month to seek out those clinical studies, position papers, or clinical guidelines that may enhance or change clinical practice. The intent of this article is to provide an updated source of new pertinent literature published in 2016. Methods To assist pharmacy clinicians engaged in nutrition support in staying current with the most pertinent literature, the principal author participant of this article (R.N.D.) invited 7 additional clinical pharmacists to participate in this project. The potential author participants were invited based on the principal author's perception of their active involvement in the field as supported by their educational, research, or professional committee involvement in pharmacy nutrition support, particularly in the American Society for Parenteral and Enteral Nutrition (ASPEN). All authors are board certified. Four author participants are board certified solely in pharmacy nutrition support, whereas others are certified in areas whereby nutrition support is part of their practice or have 720313H PXXXX10.

Hospital Pharmacy, May 25, 2019

Staying current with the literature is an essential requirement for the informed pharmacist who m... more Staying current with the literature is an essential requirement for the informed pharmacist who maintains an evidence-based clinical practice. This requirement has become more challenging to fulfill as the practice model of the traditional full-time pharmacy nutrition support specialist has changed at many institutions. Many former specialists now practice within an integrated model whereby the clinical pharmacist provides pharmacotherapy services along with nutrition support responsibilities. As a result of this change, clinicians are responsible for staying current within numerous therapeutic areas that interface with clinical practice including nutrition support. Because nutrition support therapy is integrated with many divergent specialized fields, it is an extremely daunting task for one individual to screen the abundant amount of available journals each month to seek out those clinical studies, position papers, or clinical guidelines that may enhance or change clinical practice. The intent of this article is to provide an updated source of new pertinent literature published in 2016. Methods To assist pharmacy clinicians engaged in nutrition support in staying current with the most pertinent literature, the principal author participant of this article (R.N.D.) invited 7 additional clinical pharmacists to participate in this project. The potential author participants were invited based on the principal author's perception of their active involvement in the field as supported by their educational, research, or professional committee involvement in pharmacy nutrition support, particularly in the American Society for Parenteral and Enteral Nutrition (ASPEN). All authors are board certified. Four author participants are board certified solely in pharmacy nutrition support, whereas others are certified in areas whereby nutrition support is part of their practice or have 720313H PXXXX10.

Hospital Pharmacy, 2021

Purpose: The purpose of this article is to assist the pharmacist engaged in nutrition support the... more Purpose: The purpose of this article is to assist the pharmacist engaged in nutrition support therapy in staying current with pertinent literature. Methods: Several clinical pharmacists engaged in nutrition support therapy compiled a list of articles published in 2020 considered important to their clinical practice. The citation list was compiled into a single spreadsheet where the author participants were asked to assess whether the article was considered important to nutrition support pharmacy practice. A culled list of publications was then identified whereby at least 5 out of the 8 author participants considered the paper to be important. Guideline and consensus papers from professional organizations, important to practice but not ranked, were also included. Results: A total of 169 articles were identified; 5 from the primary literature were voted by the group to be of high importance. An additional 17 guidelines, position, recommendation, or consensus papers were also identifie...

The American Journal of Clinical Nutrition, 2017

Nutrition in Clinical Practice, 2006

Background: Chronic obstructive pulmonary disease (COPD), the fifth‐leading cause of death worldw... more Background: Chronic obstructive pulmonary disease (COPD), the fifth‐leading cause of death worldwide, is characterized by chronic inflammation. However, no available agent can effectively cure this inflammation. A dietary supplement containing ω‐3 polyunsaturated fatty acids (PUFAs) has anti‐inflammatory effects. In this study, we hypothesized that nutrition support with ω‐3 PUFA‐rich diets may be useful for treating COPD, and we compared the clinical features and inflammatory mediator levels between the COPD patients who received an ω‐3 PUFA‐rich supplement and those who received a nonrich supplement. Methods: Sixty‐four COPD patients received 400 kcal per day of an ω‐3 PUFA‐rich supplement (ω‐3 group) or an ω‐3 PUFA‐nonrich supplement (ω‐6 group) for 2 years. We prospectively investigated the clinical features of these patients and measured the levels of inflammatory mediators. Results: In 6‐minute walk testing, the dyspnea Borg scale and decrease of arterial oxygen saturation mea...

American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2017

The American Journal of Medicine, 2017

We read with interest the findings of Tsapepas et al 1 associating hyponatremia with high-dose tr... more We read with interest the findings of Tsapepas et al 1 associating hyponatremia with high-dose trimethoprim (TMP) exposure. Tsapepas et al 1 assert that high doses of trimethoprim-sulfamethoxazole (TMP-SMX) have a higher incidence of hyponatremia in patients with pneumonia. However, there is a confounder regarding the dosage form, particularly the intravenous (IV) formulation, affecting the incidence of hyponatremia. Trimethoprim is least likely to precipitate in the acidic environment of diluents containing dextrose, in which 5% dextrose is the preferred diluent. 2,3 Given the mean dose of TMP and weight of patients from the article and a 5% dextrose diluent, each patient would have received a TMP-SMX dose with approximately 1 L of 5% dextrose daily. 1,3 The accumulation of excess free water from the 5% dextrose may have contributed to the higher incidence of hyponatremia with respect to total treatment dose and duration. It should be noted that TMP-SMX does have variable compatibility with 0.9% sodium chloride, along with other sodium-containing combinations of diluents that can be used as part of the IV formulation. 2 A characterization of the IV TMP-SMX formulations used in this study could result in the development of hyponatremia, and using 0.9% sodium chloride as the diluent would further strengthen the higher incidence of hyponatremia in patients given high doses of TMP-SMX.

Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition, 2006

To compare the effects of a low-carbohydrate diet and a conventional (fat- and calorie-restricted... more To compare the effects of a low-carbohydrate diet and a conventional (fat- and calorie-restricted) diet on lipoprotein subfractions and inflammation in severely obese subjects. We compared changes in lipoprotein subfractions and C-reactive protein levels in 78 severely obese subjects, including 86% with either diabetes or metabolic syndrome, who were randomly assigned to either a low-carbohydrate or conventional diet for 6 months. Subjects on a low-carbohydrate diet experienced a greater decrease in large very low-density lipoprotein (VLDL) levels (difference =-0.26 mg/dL, p = .03) but more frequently developed detectable chylomicrons (44% vs 22%, p = .04). Both diet groups experienced similar decreases in the number of low-density lipoprotein (LDL) particles (difference = -30 nmol/L, p = .74) and increases in large high-density lipoprotein (HDL) concentrations (difference = 0.70 mg/dL, p = .63). Overall, C-reactive protein levels decreased modestly in both diet groups. However, pat...

Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition, 2006

The aim of this study was to assess the efficacy of preoperative and postoperative treatment with... more The aim of this study was to assess the efficacy of preoperative and postoperative treatment with ω-3 polyunsaturated fatty acids (PUFAs) in preventing the occurrence of atrial fibrillation (AF) after coronary artery bypass graft surgery (CABG). Postoperative AF is a common complication of CABG. There is growing clinical evidence that PUFAs have cardiac antiarrhythmic effects. A total of 160 patients were prospectively randomized to a control group (81 patients, 13 female, 64.9 ± 9.1 years) or PUFAs 2 g/day (79 patients, 11 female, 66.2 ± 8.0 years) for at least 5 days before elective CABG and until the day of discharge from the hospital. The primary end point was the development of AF in the postoperative period. The secondary end point was the hospital length of stay after surgery. All end points were independently adjudicated by 2 cardiologists blinded to treatment assignment. The clinical and surgical characteristics of the patients in the 2 groups were similar. Postoperative AF...

Hospital Pharmacy, 2016

Purpose To assist the pharmacy clinician engaged in nutrition support in staying current with the... more Purpose To assist the pharmacy clinician engaged in nutrition support in staying current with the most pertinent literature. Methods Several experienced board-certified clinical pharmacists engaged in nutrition support therapy compiled a list of articles published in 2014 and 2015 that they considered to be important to their practice. Only those articles available in print format were considered for potential inclusion. Articles available only in preprint electronic format were not evaluated. The citation list was compiled into a single spreadsheet where the author participants were asked to ascertain whether they considered the paper important to nutrition support pharmacy practice. A culled list of publications was then identified whereby the majority of author participants (at least 5 out of 8) considered the paper to be important. Results A total of 108 articles were identified; 36 of which were considered to be of high importance. An important guideline article published in ea...

Acute Care of the Cancer Patient, 2005

Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition, 2003

... Ginger Langley, PharmD; Todd Canada, PharmD, BCNSP; and Lora Day, MS, RD, CNSD The University... more ... Ginger Langley, PharmD; Todd Canada, PharmD, BCNSP; and Lora Day, MS, RD, CNSD The University of Texas MD Anderson Cancer Center, Division of Pharmacy, Houston; and Department of Dietetics, Parkland Health & Hospital System, Dallas, Texas Metabolic Acidosis ...

Journal of the American Dietetic Association, 1998

Malnutrition is a common problem in cancer patients and, if untreated, can lead to cancer cachexi... more Malnutrition is a common problem in cancer patients and, if untreated, can lead to cancer cachexia and poor response to therapies. Subjective Global Assessment (SGA) has been shown to be valid and comparable with objective measures such as the Prognostic Nutritional Index (PNI) in general surgery patients. The purpose of this study was to determine the reproducibility of SGA ratings