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Papers by Canan Bor

The journal of pediatric research :/The journal of pediatric research, Mar 22, 2024

PubMed, May 1, 2009

Objective: To compare the postoperative analgesic effects of intra-articular levobupivacaine with... more Objective: To compare the postoperative analgesic effects of intra-articular levobupivacaine with bupivacaine following knee arthroscopy. Methods: Forty patients, aged between 20-60 years and undergoing elective knee arthroscopy were enrolled into the study protocol that was carried out in Tepecik Education and Research Hospital, Izmir, Turkey between January and June 2007. General anesthesia protocol was the same in all patients. At the end of surgery, the patients were randomly assigned into 2 groups (n=20 in each group). Group L received 20 ml 0.5% levobupivacaine and Group B received 20 ml 0.5% bupivacaine intra-articularly. We evaluated the level of postoperative pain (by visual analogue scale at 1, 2, 4, 6, 12, and 24 hours after surgery), first analgesic requirement time (period measured from the end of the surgery until further analgesia was demanded), and total analgesic consumption during 24 hours. Results: There were no significant difference in the postoperative pain scores of the patients between groups. The first analgesic requirement times were not statistically different. Twelve patients in Group L (60%) and 9 patients in Group B (45%) needed no additional analgesic during the 24 hours (p>0.05). No complications and side effects were found related to the intra-articular treatment. Conclusion: The results of the study show that intra-articular 20 ml 0.5% levobupivacaine provides effective analgesia comparable to that provided by 20 ml 0.5% bupivacaine.

Beyoğlu eye journal, 2022

Keratoconus is a common disorder characterized by progressive corneal steepening with eventual co... more Keratoconus is a common disorder characterized by progressive corneal steepening with eventual corneal thinning. Its prevalence is 50-230 cases/100,000 (1). It has been associated with many systemic disorders such as atopic disease, Down syndrome, osteogenesis imperfecta, joint hypermobility, and mitral valve prolapse (2). Although it is known that these patients have hyperelastic joints, temporomandibular joint (TMJ) dislocation is not a common finding. Predisposing factors for TMJ dislocation include congenital joint weakness, extreme mouth opening during yawning, dental and otorhinolaryngological treatment, trauma, and drugs, especially the anti-emetics (metoclopramide) and phenothiazines (Compazine), which produce extrapyramidal effects, hypermobility, associated with systemic diseases, and psychogenic and neurological disorders (3). Herein, bilateral TMJ dislocation in a keratoconus patient under general anesthesia during supraglottic airway device placement before deep anterior lamellar keratoplasty (DALK) is reported.

Ain-Shams Journal of Anesthesiology

Background Central venous catheterization (CVC) is a commonly used procedure in pediatric surgery... more Background Central venous catheterization (CVC) is a commonly used procedure in pediatric surgery and intensive care units. For some reasons, catheterizations in children are technically more difficult in comparison to adult patients. The purpose of this study is to evaluate the CVC procedures performed with the aid of anatomic landmarks by experienced (35, 14, 4 years of experience) anesthesiologists and the associated complications. A total of 498 cases under the age of 18 who underwent CVC (temporary, port, or Hickman) between the years 2014 and 2017 were included in this retrospective study. All catheters were inserted with the aid of anatomic landmarks. Results The mean age of the patients was 47.1 ± 59.2 months and 54.8% were male. By using anatomical landmarks, the average success rate in central venous catheterizations was calculated as 98.6%. Complications developed included arterial puncture in 8% (n 40), temporary arrhythmia in 6.2% (n 31) and pneumothorax in 1.4% (n 7) o...

Calismaya 18-65 yas arasi, maske anestezisi altinda uterus kuretaji uygulanacak, ASA I-II, 105 ha... more Calismaya 18-65 yas arasi, maske anestezisi altinda uterus kuretaji uygulanacak, ASA I-II, 105 hasta dahil edildi. Hastalar randomize 3 gruba ayrildi. Grup R (n=35) remifentanil 1 μg/kg, Grup A (n=35) alfentanil 10 μg/kg ve Grup F (n=35) fentanil 1 μg/kg uygulanmasini takiben bolus 2 mg/kg propofol IV verildi. Hemodinamik parametreler, spontan solunumun baslamasi, girisimin bitiminden sonra sozlu uyariya verbal cevap zamani, postoperatif uniteye cikarilma zamani, yan etkiler ve girisim sonunda kullanilan toplam propofol miktari, postoperatif derlenme skoru (Aldrete) ve anestezi sonrasi taburcu etme skorlama sistemi (PADSS) skorlari uc grup arasinda karsilastirildi. Hemodinamik veriler karsilastirildiginda bazal degerler arasinda fark yok iken induksiyon sonrasi 1, 3 ve 5.dk.’larda grup remifentanil’de sistolik ve diastolik arter basinclari (SAB, DAB), kalp atim hizi (KAH), SpO2 degerlerinde dusme saptandi ve fark istatistiksel olarak anlamli bulundu (p

Turkish Journal of Psychiatry, 2021

Covid-19 pandemisinde sağlık çalışanlarında anksiyete, stres, tükenmişliğin gözlendiği bildirilme... more Covid-19 pandemisinde sağlık çalışanlarında anksiyete, stres, tükenmişliğin gözlendiği bildirilmektedir. Bu çalışmada pandemi hastanesi ilan edilen üçüncü basamak bir üniversite hastanesinde sağlık çalışanlarıyla birlikte yardımcı personelde anksiyete, tükenmişlik düzeyleri ve tükenmişlikle ilişkili risk faktörlerinin belirlenmesi amaçlanmıştır. Yöntem: Hastanemizdeki çalışanlara ulaştırılmış olan anket formunu, Hastane Anksiyete Depresyon (HAD) Ölçeği ve Maslach Tükenmişlik Ölçeğini 15-30 Nisan 2020 tarihleri arasında doldurmuş olan 683 kişi çalışmaya alınmıştır. Bulgular: Çalışmamızda stres, depresyon ve anksiyete düzeyleri hemşirelerde diğer gruplara göre istatistiksel açıdan anlamlı düzeyde yüksek bulunmuştur. Tükenmişlik açısından bakıldığında, asistanlarda ve hemşirelerde duygusal tükenme, duyarsızlaşma puanları diğer gruplara göre daha yüksek, kişisel başarı puanları daha düşük bulunmuştur. Ön saflarda (Covid-19 birimleri) çalışıyor olmak tükenmişlik, anksiyete, stres, depresyon düzeylerini etkilemezken, bekar olmak, çocuk sahibi olmak, evinden ayrı yaşamak tükenmişlik düzeylerini etkilemiştir. Tüm örneklemde duygusal tükenmişliği en fazla arttıran risk etmenleri HAD Ölçeği anksiyete ve depresyon için belirlenmiş kesme puanına göre anksiyete bozukluğu (OR:7,19) ve depresyon (OR: 3,43); duyarsızlaşma riskini en fazla arttıran risk etmeni ise anksiyete bozukluğu olmuştur. Hemşirelerde yoğun çalışma saatlerinden şikayet edenlerde etmeyenlere göre duyarsızlaşma riski 2,7 kat daha fazladır. Tüm grupta iş ve aileden alınan sosyal desteğin duyarsızlaşma açısından koruyucu olduğu bulunmuştur. Sonuç: Covid-19 pandemisinde sağlık çalışanlarının iyilik hali olumsuz etkilenmiştir. Depresyon ve anksiyete varlığı tükenmişlik gelişimi riskini arttırmıştır. Sosyal desteğin tükenme açısından koruyucu olduğu söylenebilir. Bu nedenle sağlık çalışanlarının ruh sağlığının korunması ve tükenmemeleri için etkin psikososyal, örgütsel müdahalelerin acilen hayata geçirilmesi büyük önem taşımaktadır.

American Journal of Physiology-Gastrointestinal and Liver Physiology, 1998

Epidemiological studies indicate a relationship between alcohol consumption and esophageal epithe... more Epidemiological studies indicate a relationship between alcohol consumption and esophageal epithelial disease. We therefore sought the contribution of the direct effects of ethanol on esophageal epithelial structure and (transport and barrier) function. Epithelium from the rabbit was mounted in Ussing chambers and exposed luminally for 1 h to 1–40% ethanol. At concentrations of 1–5% potential difference (PD) increased, and at 10–40% PD decreased. The increase in PD with 1–5% ethanol was accompanied by an increase in short-circuit current ( Isc), and this increase in Isccould be blocked by ouabain pretreatment. The decrease in PD with 10–40% ethanol was associated with a decrease in electrical resistance ( R), and this decrease in R was paralleled by an increase in transepithelial [14C]mannitol flux. Reversibility of these changes was limited at ethanol concentrations ≥10%, and these were associated morphologically by patchy or diffuse tissue edema. Moreover, as with ethanol exposure...

Digestive Diseases and Sciences - DIGEST DIS SCI, 1999

Heavy alcohol consumption is associated with thedevelopment of reflux esophagitis. Among the reas... more Heavy alcohol consumption is associated with thedevelopment of reflux esophagitis. Among the reasons forthis are impairment of the antireflux barrier,stimulation of acid secretion, and altered tissue resistance. To explore the contribution ofaltered tissue resistance to the development ofesophagitis, sections of rabbit esophageal epitheliumwere mounted in Ussing chambers and exposed luminally to 10% ethanol, acid (HCl, pH 2), or combinationsof both. Tissue injury was assessed by measurements ofpotential difference (PD), short circuit current(Isc) and electrical resistance (R) and byhistology. Tissues exposed luminally to HCl for 1 hrexhibited little or no change electrically ormorphologically compared to Ringer controls, whileluminal exposure to 10% ethanol for 1 hr lowered PD (53± 4%), Isc (30 ± 1%), and R (31± 5%) and produced cellular edema in the upperlayers. Simultaneous exposure to ethanol and acidresulted in significantly greater declines in PD (81± 1%) and Isc (70 ± 2%), but...

Regional Anesthesia and Pain Medicine, 2007

Conclusion: The results of the study show that intraarticular 20 ml 0.5% levobupivacaine provides... more Conclusion: The results of the study show that intraarticular 20 ml 0.5% levobupivacaine provides effective analgesia comparable to that provided by 20 ml 0.5% bupivacaine.

Annals of Internal Medicine, 1999

TO THE EDITOR: Dr. Davidoff&amp;amp;#39;s provocative editorial on the paradoxes of alter... more TO THE EDITOR: Dr. Davidoff&amp;amp;#39;s provocative editorial on the paradoxes of alternative care (1) poses the question, What can be learned ? An answer relevant to this query emerged from a 1980 point-counterpoint debate on the merits of holistic medicine. The event was sponsored by the American Association for the Advancement of Science as part of its Congressional Science Fellowship program. It featured the contrasting views of a practitioner of orthodox medicine, recruited from the upper echelons of the American Medical Association, and those of a former homemaker who had opened a clinic for holistic medicine after receiving a vision during a dream to do so. In due course, the participants were asked how one might identify good practitioners of conventional medicine on the one hand versus holistic medicine on the other. The physician took minutes to describe the scientific method and the manner in which good physicians applied it at bedside and bench. The advocate for holistic medicine answered with a response distinguished by its clarity and brevity: They make me feel better. Making the patient feel better is not a goal that traditional medicine can always achieve, but it is a goal to which every orthodox physician can aspire.

Amaç: komplikasyonlar sıklıkla görülmektedir. Bu çalışmada, akut pankreatite bağlı gelişen pulmon... more Amaç: komplikasyonlar sıklıkla görülmektedir. Bu çalışmada, akut pankreatite bağlı gelişen pulmoner komplikasyonlar nedeniyle mekanik ventilasyon uygulanan hastalarda bilgisayarlı tomografi şiddet indeksi (CTSI) ve geleneksel iki farklı skorlama sistemi olan APACHE II ve Ranson skorlama sistemlerinin uygulanabilirliği ve güvenilirliğinin karşılaştırılması amaçlandı. Gereç ve Yöntem: Çalışmaya, akut pankreatit tanısı ile mekanik ventilasyon uygulanan toplam 36 hasta dahil edildi. Mortalite oranlarının öngörülmesi için CTSI, APACHE II ve Ranson skorlama sistemleri kullanıldı. Bulgular: Toplam 36 hasta içinden sağ kalan hasta sayısı dokuz (%25) idi. Mortalite oranları yoğun bakımda %66.6 (n=24), hastanede ise %75 (n=27) olarak bulundu. Mortaliteyi öngörme konusunda 17'nin üzerinde APACHE II skoru en yüksek sensitivite (%64) ve spesifiteye (%66) sahipti. Bu oranları sırasıyla 4'ün üzerinde CTSI skoru (sensitivite %60, spesifite %40) ve 6 'nın üzerinde Ranson skoru (sensitivi...

Amac: Karaciger transplant hastalarinda dusuk serum albumin duzeylerinin kotu prognoz belirtisi o... more Amac: Karaciger transplant hastalarinda dusuk serum albumin duzeylerinin kotu prognoz belirtisi oldugu ve bu hastalarda erken postoperatif donemde ciddi hipoalbuminemi gelisebilecegi bildirilmistir. Yogun bakimimizda serum albumin duzeyi 3.0 g.dL-1 altinda belirlenen karaciger alicilarina rutin olarak human albumin replasmani uygulamaktadir. Calismamizin amaci karaciger transplantasyonu uygulanan hastalarda postoperatif devrede uygulanan albumin replasmani stratejisinin retrospektif olarak degerlendirilmesidir. Gerec ve Yontem: 81 karaciger alicisi 2 gruba ayrildi. Albumin grubunu [Alb(+) grubu, n=57] serum albumin duzeyi 3.0 g dL-1 uzerine yukselene kadar % 20 human albumin replasmani uygulanan hastalar olusturdu. Diger grubu [Alb(–) grubu, n=24] ise yatis suresince albumin replasmani uygulanmayan hastalar yer aldi. Bulgular: Alb(+) grubunda yatistaki ortalama albumin duzeyi 2.5±0.4 g.dL-1, taburcu olurken ortalama albumin duzeyi 2.7±0.6 g.dL-1 olarak belirlendi (p= 0.075). Elli ye...

Ege Tıp Dergisi, 2022

Mulvihill-Smith sendromu, sistem ve organ tutulumu olan nadir görülen genetik bir bozukluktur. Ak... more Mulvihill-Smith sendromu, sistem ve organ tutulumu olan nadir görülen genetik bir bozukluktur. Akraba evliliğinden doğan çocuklarda ve hem kadın hem de erkek cinsiyette görülmesi otozomal resesif kalıtımı düşündürür. Bu sendromda yaşlı yüz görünümü tipik olması yanında kısa boy, mikrosefali, yüz ve gövdede multipl nevuslar, yüksek-tiz ses, hipertelorizm, genital anomaliler, görme kusuru, diyabet, tekrarlayan enfeksiyonlar, immun yetmezlik, işitme azlığı, tümör gelişimi (mide, dil, pankreas ve melanom), hipodonti, orofasiyal-dental anormallikler ve mental retardasyon görülen bulgulardandır. Anestezi yönetimi; zor havayolu, glisemik instabilite ve hastaların geriyatrik hasta grubunda kabul edilmeleri açısından önemlidir. Literatürde oldukça az sayıda anestezi deneyimi sunulmuş olgu sunumları mevcuttur. Bu nedenle; Mulvihill-Smith sendromu tanılı 17 yaş kadın hastamızda uyguladığımız anestezi yönetimini sunmayı amaçladık.

The Eurasian Journal of Medicine, 2022

OBJECTIVE Perioperative hypothermia occurs in the pediatric age group in the perioperative period... more OBJECTIVE Perioperative hypothermia occurs in the pediatric age group in the perioperative period at a high rate. In this study, it is aimed to reveal the incidence of perioperative hypothermia and the risk factors that play a role in its development in pediatric circumcision cases that have a brief operation duration. MATERIALS AND METHODS This prospective observational cohort study included 100 children who underwent circumcision under general anesthesia. All patients were heated with a passive heater and hypothermia was interpreted as a drop in body temperature below <36˚C. The patients were divided into 2 groups: group 1 (patients with body temperature <36˚C) and group 2 (≥36˚C). Demographic data, the American Society of Anesthesiologists' Classification of Physical Health Score, premedication method, operation time, fluid amount, preoperative and postoperative temperature of patients as tympanic were recorded. RESULTS The average age of the patients was 70 ± 40 months (median: 84) and 93% were ASA I. In 71% of patients, a decrease in body temperature and hypothermia developed in 39% compared to baseline. The duration of operation was longer in the group with hypothermia (30 min [15-70] vs. 25 min [15-60], P < .001). Only the duration of operation was determined as the independent risk factor associated with hypothermia (odds ratio: 1.103 [1.017-1.197], P=.018). CONCLUSION In this study, it was found that high rates of hypothermia developed even in minor operations such as pediatric circumcision. The risk of hypothermia increases with the prolongation of surgery.

Transuretral cerrahi yuzeyel mesane tumorlerinin ilk basamak tedavisinde altin standart yontemdir... more Transuretral cerrahi yuzeyel mesane tumorlerinin ilk basamak tedavisinde altin standart yontemdir. Mesane boynu, trigon ve lateral duvar yerlesimli tumorlerin rezeksiyonu sirasinda obturator sinir stimulasyonuna bagli uyluk adduktor kaslarinda istenmeyen kasilmalar olusabilir. Mesane duvarinin rezeksiyon loopuna dogru ani hareketlenmesi mesane perforasyonuna neden olabilir. Adduktor kaslarda olusan bu ani spazmi onlemek amaciyla cesitli yontemler kullanilmistir. Bu yazimizda adduktor kas spazmini engellemede etkili bir yontem olan obturator sinir blogunun anatomisi, teknik ve sonuclarini tartistik.