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Papers by Carine Munaut

Research paper thumbnail of Effect of anti-apoptotic drugs to prevent follicles loss during ovarian cortex transport and cryopreservation

Research paper thumbnail of G-CSF as a non-invasive predictive marker for embryo implantation

Research paper thumbnail of Ovarian tissue recovery in SCID and NOD-SCID mice after VEGF111 or VEGF165 graft treatment

Research paper thumbnail of Do anti-apoptotic drugs prevent follicles loss during ovarian cortex transport and cryopreservation?

Research paper thumbnail of Impact of mice strains in ovarian tissue recovery after VEGF111 or VEGF165 graft treatment

Research paper thumbnail of Influence of VEGF111 treatment on ovarian tissue xenografts in different mice strains

Research paper thumbnail of Impact of mice strains in ovarian tissue recovery after VEGF111 graft treatment

Research paper thumbnail of Limitation of damage to ovarian cortex during cryopreservation by addition of anti-apoptotic drugs in transport and freezing media

Research paper thumbnail of Comparison of different mice strains to test ovarian VEGF111 treated graft recovery

Research paper thumbnail of Assessment of follicular density in sheep ovarian tissue and impact on experimental results

Research paper thumbnail of ADAMTS-1 Metalloproteinase Promotes Tumor Development through the Induction of a Stromal Reaction <i>In vivo</i>

Cancer Research, Nov 14, 2008

Research paper thumbnail of Neonatal Hypoxic-Ischemic Encephalopathy: a new view of an old problem

Neonatal hypoxic-ischemic encephalopathy (HIE) remains a challenge of perinatal medicine. It is a... more Neonatal hypoxic-ischemic encephalopathy (HIE) remains a challenge of perinatal medicine. It is an important cause of long term morbidity, including motor and behavioral deficits, mental retardation, seizures and cerebral palsy, and mortality in newborns. This paper reviews the pathophysiology and current concepts of the management of neonatal HIE as well as the future potential neuroprotective strategies for attenuation of this disease.Peer reviewe

Research paper thumbnail of L’expérimentation animale reste indispensable (OPINION)

audience: researcher, professional, student, popularizationTrop fréquemment, l’expérimentation an... more audience: researcher, professional, student, popularizationTrop fréquemment, l’expérimentation animale est présentée comme une pratique archaïque. Elle a bien changé. Et 100 % des patients traités le sont grâce aux concepts et techniques développés grâce à elle

Research paper thumbnail of Absence of correlation between follicular fluid volume and follicular granulocyte colony-stimulating factor, a predictor of embryo implantation and successful delivery

Gynecological Endocrinology, 2019

Research paper thumbnail of Emerging roles for proteinases in cancer

Invasion & metastasis, 1997

Metalloproteinases and serine proteinases have been associated with tumor invasion and formation ... more Metalloproteinases and serine proteinases have been associated with tumor invasion and formation of metastasis which represent the major obstacles to cancer cure. The contribution of proteinases in these processes was initially thought to be the destruction of extracellular matrices. However, recent evidence suggests that they mainly affect tumor growth rather than invasion. Proteinases can indeed generate active matrix protein fragments, influence the release, the activation and the bioavailability of growth factors, and consequently modulate tumor cell growth, apoptosis and angiogenesis. Additionally, proteinases, their receptors and/or inhibitors can be directly involved in cell migration and in the processing or shedding of cell surface proteins. Further elucidation of the functions of proteinases is essential for the development of novel anticancer strategies.

Research paper thumbnail of Soluble forms of VEGF receptor‐1 and ‐2 promote vascular maturationviamural cell recruitment

Research paper thumbnail of Angiogenic activity of human chorionic gonadotropin through LH receptor activation on endothelial and epithelial cells of the endometrium

Research paper thumbnail of Evidence for cross-talk between the LH receptor and LH during implantation in mice

Reproduction, Fertility and Development, 2013

The present study investigated the first interaction that occurs between the blastocyst and endom... more The present study investigated the first interaction that occurs between the blastocyst and endometrium during implantation. Given the ethical objections to studying implantation in humans, a mouse model was used to study the dialogue between luteinising hormone (LH) and luteinising hormone receptor (LHCGR). Several studies performed on LHCGR-knockout mice have generated controversy regarding the importance of the dialogue between LH and LHCGR during implantation. There has been no demonstration of a bioactive LH-like signal produced by the murine blastocyst. The first aim of the present study was to examine and quantify, using radioimmunoassay, the generation of a bioactive LH signal by the murine blastocyst. We went on to examine and quantify endometrial Lhcgr expression to validate the mouse model. Expression of LHCGR in mouse uteri was demonstrated using immunohistochemistry and western blot analysis. To quantify the expression of Lh in the mouse blastocyst and Lhcgr in the endo...

Research paper thumbnail of Strategies for Using the Sheep Ovarian Cortex as a Model in Reproductive Medicine

Research paper thumbnail of Peri-conceptual cytokine environment and consequences for human pregnancy

Journal of Reproductive Immunology, 2010

Research paper thumbnail of Effect of anti-apoptotic drugs to prevent follicles loss during ovarian cortex transport and cryopreservation

Research paper thumbnail of G-CSF as a non-invasive predictive marker for embryo implantation

Research paper thumbnail of Ovarian tissue recovery in SCID and NOD-SCID mice after VEGF111 or VEGF165 graft treatment

Research paper thumbnail of Do anti-apoptotic drugs prevent follicles loss during ovarian cortex transport and cryopreservation?

Research paper thumbnail of Impact of mice strains in ovarian tissue recovery after VEGF111 or VEGF165 graft treatment

Research paper thumbnail of Influence of VEGF111 treatment on ovarian tissue xenografts in different mice strains

Research paper thumbnail of Impact of mice strains in ovarian tissue recovery after VEGF111 graft treatment

Research paper thumbnail of Limitation of damage to ovarian cortex during cryopreservation by addition of anti-apoptotic drugs in transport and freezing media

Research paper thumbnail of Comparison of different mice strains to test ovarian VEGF111 treated graft recovery

Research paper thumbnail of Assessment of follicular density in sheep ovarian tissue and impact on experimental results

Research paper thumbnail of ADAMTS-1 Metalloproteinase Promotes Tumor Development through the Induction of a Stromal Reaction <i>In vivo</i>

Cancer Research, Nov 14, 2008

Research paper thumbnail of Neonatal Hypoxic-Ischemic Encephalopathy: a new view of an old problem

Neonatal hypoxic-ischemic encephalopathy (HIE) remains a challenge of perinatal medicine. It is a... more Neonatal hypoxic-ischemic encephalopathy (HIE) remains a challenge of perinatal medicine. It is an important cause of long term morbidity, including motor and behavioral deficits, mental retardation, seizures and cerebral palsy, and mortality in newborns. This paper reviews the pathophysiology and current concepts of the management of neonatal HIE as well as the future potential neuroprotective strategies for attenuation of this disease.Peer reviewe

Research paper thumbnail of L’expérimentation animale reste indispensable (OPINION)

audience: researcher, professional, student, popularizationTrop fréquemment, l’expérimentation an... more audience: researcher, professional, student, popularizationTrop fréquemment, l’expérimentation animale est présentée comme une pratique archaïque. Elle a bien changé. Et 100 % des patients traités le sont grâce aux concepts et techniques développés grâce à elle

Research paper thumbnail of Absence of correlation between follicular fluid volume and follicular granulocyte colony-stimulating factor, a predictor of embryo implantation and successful delivery

Gynecological Endocrinology, 2019

Research paper thumbnail of Emerging roles for proteinases in cancer

Invasion & metastasis, 1997

Metalloproteinases and serine proteinases have been associated with tumor invasion and formation ... more Metalloproteinases and serine proteinases have been associated with tumor invasion and formation of metastasis which represent the major obstacles to cancer cure. The contribution of proteinases in these processes was initially thought to be the destruction of extracellular matrices. However, recent evidence suggests that they mainly affect tumor growth rather than invasion. Proteinases can indeed generate active matrix protein fragments, influence the release, the activation and the bioavailability of growth factors, and consequently modulate tumor cell growth, apoptosis and angiogenesis. Additionally, proteinases, their receptors and/or inhibitors can be directly involved in cell migration and in the processing or shedding of cell surface proteins. Further elucidation of the functions of proteinases is essential for the development of novel anticancer strategies.

Research paper thumbnail of Soluble forms of VEGF receptor‐1 and ‐2 promote vascular maturationviamural cell recruitment

Research paper thumbnail of Angiogenic activity of human chorionic gonadotropin through LH receptor activation on endothelial and epithelial cells of the endometrium

Research paper thumbnail of Evidence for cross-talk between the LH receptor and LH during implantation in mice

Reproduction, Fertility and Development, 2013

The present study investigated the first interaction that occurs between the blastocyst and endom... more The present study investigated the first interaction that occurs between the blastocyst and endometrium during implantation. Given the ethical objections to studying implantation in humans, a mouse model was used to study the dialogue between luteinising hormone (LH) and luteinising hormone receptor (LHCGR). Several studies performed on LHCGR-knockout mice have generated controversy regarding the importance of the dialogue between LH and LHCGR during implantation. There has been no demonstration of a bioactive LH-like signal produced by the murine blastocyst. The first aim of the present study was to examine and quantify, using radioimmunoassay, the generation of a bioactive LH signal by the murine blastocyst. We went on to examine and quantify endometrial Lhcgr expression to validate the mouse model. Expression of LHCGR in mouse uteri was demonstrated using immunohistochemistry and western blot analysis. To quantify the expression of Lh in the mouse blastocyst and Lhcgr in the endo...

Research paper thumbnail of Strategies for Using the Sheep Ovarian Cortex as a Model in Reproductive Medicine

Research paper thumbnail of Peri-conceptual cytokine environment and consequences for human pregnancy

Journal of Reproductive Immunology, 2010

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