Carlos Chong - Academia.edu (original) (raw)
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Papers by Carlos Chong
Reunión de educadores en la química, Aug 12, 2015
Molecules, 2018
Amino-bridged gel polymer P1 was discovered to catalyze alkyne halo-functionalization in excellen... more Amino-bridged gel polymer P1 was discovered to catalyze alkyne halo-functionalization in excellent yields, regioselectivity, functional group compatibility, and recyclability. We have observed that both aromatic and aliphatic alkynes can be converted to α,α-dihalogenated ketones in the presence of polymer P1 under metal-free conditions at room temperature within a short reaction time.
Tetrahedron Letters, 2017
An efficient synthesis of functionalized 1,3-dihydro-2H-pyrrol-2-one was developed based on a [3+... more An efficient synthesis of functionalized 1,3-dihydro-2H-pyrrol-2-one was developed based on a [3+2] cycloaddition reaction of aza-oxyallylic cations and alkynes. With this novel method, a variety of substituted alkynes were readily converted into their corresponding pyrrolidinone analogues at room temperature. The protocol features easy operation, ambient temperature, good yields, readily available starting materials, and broad functional group tolerance. Key word: Aza-oxyallylic Cation; Alkynes; Cycloaddition Highlights Efficient synthesis of functionalized 1,3-dihydro-2H-pyrrol-2-one [3+2] Cycloaddition reaction of aza-oxyallylic cations and alkynes Easy operation, ambient temperature, good yields Broad functional group tolerance
Reunión de educadores en la química, Aug 12, 2015
Molecules, 2018
Amino-bridged gel polymer P1 was discovered to catalyze alkyne halo-functionalization in excellen... more Amino-bridged gel polymer P1 was discovered to catalyze alkyne halo-functionalization in excellent yields, regioselectivity, functional group compatibility, and recyclability. We have observed that both aromatic and aliphatic alkynes can be converted to α,α-dihalogenated ketones in the presence of polymer P1 under metal-free conditions at room temperature within a short reaction time.
Tetrahedron Letters, 2017
An efficient synthesis of functionalized 1,3-dihydro-2H-pyrrol-2-one was developed based on a [3+... more An efficient synthesis of functionalized 1,3-dihydro-2H-pyrrol-2-one was developed based on a [3+2] cycloaddition reaction of aza-oxyallylic cations and alkynes. With this novel method, a variety of substituted alkynes were readily converted into their corresponding pyrrolidinone analogues at room temperature. The protocol features easy operation, ambient temperature, good yields, readily available starting materials, and broad functional group tolerance. Key word: Aza-oxyallylic Cation; Alkynes; Cycloaddition Highlights Efficient synthesis of functionalized 1,3-dihydro-2H-pyrrol-2-one [3+2] Cycloaddition reaction of aza-oxyallylic cations and alkynes Easy operation, ambient temperature, good yields Broad functional group tolerance