Carlos Daniel Soto Teran - Academia.edu (original) (raw)

Papers by Carlos Daniel Soto Teran

Gaceta Médica Boliviana

El síndrome de Cook fue descrito por primera vez por Cook y colaboradores en 1985. Este se caract... more El síndrome de Cook fue descrito por primera vez por Cook y colaboradores en 1985. Este se caracteriza por una historia familiar de hipoplasia congénita de las uñas de las manos en los dígitos 1,2 y 3, ausencia de las uñas en los dígitos 4 y 5, braquidactilia del digito 5 de las manos y ausencia complete de las uñas de los pies. Además, puede existir una hipoplasia o ausencia de las falanges distales en los pies y las manos. La oficina de enfermedades raras del Instituto Nacional de Salud, considera este síndrome como una “enfermedad rara”. Presentamos el caso de un recién nacido con anoniquia congénita en ambas manos y pies en el digito 2 asociado a hipoplasia ungueal en dígitos 1 y 3 respetando dígitos 4 y 5. La radiografía de los dedos no muestra anormalidades en las falanges. Este caso podría representar una variante del síndrome de Cook o una nueva enfermedad aun no descrita debido a la existencia de una historia familiar importante con similares deformidades en la madre, la ab...

Pediatrics International, 2020

Revista Peruana De Quimica E Ingenieria Quimica, 2007

El objetivo del trabajo es mostrar el uso del sulfaio de cobre para obtener alcohol deshidratado ... more El objetivo del trabajo es mostrar el uso del sulfaio de cobre para obtener alcohol deshidratado a partir de alcohol rectificado industrial de 96º G. L. El tiempo requerido para la deshidratación total del alcohol fue de 60 minutos. La pureza del alcohol deshidratado se comprobó por la medición de su indice de refracción y por comparación con un patrón MERCK y 100 G.L. a 24ºC.

Quiero agradecer a Dios por brindarme la oportunidad de asumir un nuevo reto en mi vida y cumplir... more Quiero agradecer a Dios por brindarme la oportunidad de asumir un nuevo reto en mi vida y cumplirlo. A Xavier Castellanos porque sin su ayuda y apoyo este trabajo no hubiera sido posible, a Adriana por su amor y apoyo incondicional en todo momento y finalmente a mis compañeros, Melissa, Diego, Johann y Edison quienes también fueron pilar fundamental para la obtención de esta meta. iv DEDICATORIA Quiero dedicar este trabajo a mi familia, padres y hermanos que siempre me han brindado su apoyo incondicional en todo momento, ayudándome a ser la persona que soy. v RESUMEN Este documento tiene por objetivo presentar el desarrollo de un plan de negocios de acuerdo a un análisis de viabilidad financiera para el "Edificio Urbano 4" que es un proyecto inmobiliario ubicado en la zona norte de la ciudad de Quito en el sector de San Isidro del Inca, cuyos promotores y constructores son Flores-Gordillo Arquitectos, profesionales independientes con experiencia en el sector de la construcción y planificación de obra, en especial de proyectos habitacionales. El proyecto se desarrolla en un área de terreno de 787,50 m², con un total de 18 departamentos de 2 y 3 dormitorios desde 59 m² hasta 119 m² clasificados en 10 departamentos de 2 dormitorios y 8 departamentos de 3 dormitorios, 18 parqueaderos en subsuelo y 2 exteriores, área comunal abierta y cerrada en planta baja y áreas exclusivas y comunales abiertas en terraza, con un total de 2.600 m² en áreas construidas y 770 m² en áreas abiertas. El perfil del cliente está conformado por personas y familias de un Nivel Socio Económico (NSE) medio y medio alto con un ingreso promedio familiar entre $ 2000 USD a $ 2500 USD. El análisis financiero del proyecto da como resultado que el mismo es viable y rentable para los promotores, considerando una tasa de descuento del 20%, el margen de utilidad es del 21% con un VAN positivo de $141.643 USD, en un ciclo de vida del proyecto de 18 meses. El proyecto presenta un bajo riesgo en cuanto a factores externos, debido a la alta flexibilidad que presenta al aumento de los costos de construcción a la baja de los precios de venta y a la disminución de la velocidad de ventas vi ABSTRACT This document has as an objective to present the development of a business plan according to a financial viability analysis for the "Edificio Urbano 4" Project. This is a real estate project located in the North side of the city of Quito in the San Isidro del Inca sector, which is promoted and constructed by Flores-Gordillo Arquitectos, independent professionals with experience in building planning and

BMJ case reports, Jan 3, 2014

American Journal of Gastroenterology, 2000

Thrombocytopenia or leukopenia in patients with chronic liver disease is often attributed to func... more Thrombocytopenia or leukopenia in patients with chronic liver disease is often attributed to functional overactivity of the spleen (hypersplenism). Despite being a fairly common phenomenon, there is a paucity of reports on the prevalence of this syndrome in stable chronic liver disease patients with or without severe fibrosis/cirrhosis. The aim of this study was to establish the prevalence of peripheral blood cytopenia in patients with nonalcoholic cirrhosis/severe fibrosis versus patients with mild or no fibrosis on liver biopsy. This is a retrospective chart review of 235 patients who underwent a liver biopsy. One hundred ninety-one patients met strict criteria for study entry; 28 different clinical and laboratory variables were collected from their charts review, and data were then analyzed using the SPSS statistical package. Of the cirrhotic patients, 64% were noted to have platelet counts consistently below 150,000 (lower limit of normal in our laboratory; mean, 144.6 +/- 89.4; median, 114), whereas only 5.5% of noncirrhotic patients had thrombocytopenia (mean, 252.2 +/- 103.4; median, 238). Leukopenia (WBC, <3,500) was relatively rare in the cirrhotic/fibrotic group, having a prevalence of 5% (7.59 +/- 4.3) versus 3.3% (10.62 +/- 14.2) of noncirrhotic patients. Of the patients with cirrhosis, 64% had thrombocytopenia (platelet count, <150,000). The likelihood ratio of finding a platelet count of <100,000 in patients with cirrhosis, as opposed to patients without cirrhosis, is almost 12.

Community-acquired methicillin-resistant Staphylococcus aureus has become a wellestablished patho... more Community-acquired methicillin-resistant Staphylococcus aureus has become a wellestablished pathogen with alarming rates during the last decade. The current situation of this bacteria in pediatric infections is very limited and motivated us to conduct this study. This is a retrospective and analytical study including patients less than 18 years of age with the diagnosis of skin or soft tissue infections in 2008 and 2009 meeting the criteria of Community-acquired infection. A prevalence of 41.9% among skin and soft tissue infections was found. Inducible resistance to clindamycin was detected in 1.3% of the strains and the infection shows a seasonal predilection for summer (P=0.003); 57.8% of the cases required hospitalization with a mean stay of 3.3±2.5 days. The susceptibility to clindamycin and co-trimoxazole is 88 and 97% respectively. The resistance to erythromycin has reached 92%. The main diagnoses at presentation was gluteal abscess plus cellulitis (34.2%). The prevalence of CA-MRSA is trending up and seems to become a large burden for the health system in our community. Clindamycin is still an excellent option in the community setting since inducible clindamycin resistance is extremely low in this community. Co-trimoxazole should be kept as a reserved drug to avoid the rapid resurgence resistance in the community.

Clinics and Practice, 2011

Silver nitrate is commonly recognized for the toxic effects followed by the direct contact with t... more Silver nitrate is commonly recognized for the toxic effects followed by the direct contact with the skin and mucosa known as argyria, but there is surprisingly little information about the adverse effects of silver nitrate after ingestion. Since only a few cases were reported in the literature, the aim of this case is to enrich the little experience existent about the possible effects of silver nitrate ingestion. We describe the case of a 15-year-old female who intentionally ingested 15cc of silver nitrate solution in a suicidal attempt. The clinical picture included an excruciating burning sensation in her throat and nostrils followed by vomiting and poor oral intake. The presence of a whitish membrane on the oral and buccal mucosa without bleeding or erosions was the only remarkable finding at physical examination. Unlike the rest of the cases described in the literature the clinical and endoscopic follow up of the patient was benign and without sequela or signs of oesophageal dam...

Pediatrics International, 2012

Pediatric emergency care, 2012

The aim of this study was to analyze the value of performing laboratory tests, taking cultures, a... more The aim of this study was to analyze the value of performing laboratory tests, taking cultures, and imaging, a diagnostic approach for febrile seizures (FSs) still routinely performed despite the American Academy of Pediatrics recommendations not to. Another aim of this study was to identify the most common sources of fever in patients with FSs and to determine whether the occurrence of FSs correlates with the seasons of the year. This is a retrospective study that included all patients diagnosed with simple or complex FSs who were seen in the emergency room or inpatient unit from January 2004 to December 2009. Of the 219 patients included in the study, 135 (61.4%) cases had the etiology of the FS diagnosed. Upper respiratory tract infection, otitis media, urinary infection, and pneumonia were the most common diagnoses attributed to the fever. Leukocytosis was present in 48 (24%) of 219, and neutrophilia in 199 (91%) of 219 cases. Low bicarbonate levels were common among every age g...

Current Gastroenterology Reports, 1999

Case Reports, 2009

A 15-month-old monozygotic twin infant girl with a history of intrauterine growth retardation was... more A 15-month-old monozygotic twin infant girl with a history of intrauterine growth retardation was admitted to hospital for an acute diarrhoea syndrome. Physical examination revealed asymmetry of the lower and upper limbs for length and width (fig 1A). Other findings included a small triangular face with frontal bossing, lips with downturned corners, micrognathia, and clinodactyly of the fifth finger on both hands (fig …

Clinics and Practice, 2011

Endocarditis is a rare presentation of group B streptococcal infection. Its association with pulm... more Endocarditis is a rare presentation of group B streptococcal infection. Its association with pulmonary septic embolism was only barely studied and limited data is available up to date. Multiple septic emboli is a common complication of bacterial endocarditis, but only a few cases have been documented in relation to group B streptococcus. We present the case of an 87 year old female patient with multiple underlying conditions that predisposed the development of bacterial endocarditis secondary to group B streptococcus and subsequently multiple pulmonary septic emboli. The patient was treated with ceftriaxone and azythromycin with good response and complete recovery without any further complications. In the event of a diagnosed case of group B streptococcus endocarditis, there should be a low threshold for the suspicion of septic pulmonary emboli especially in cases with right valves involvement.

The Modern Language Journal, 1961

Page 1. El Concepto del Espacio en la Literatura NO SE desarrollan las ciencias, las artes, la li... more Page 1. El Concepto del Espacio en la Literatura NO SE desarrollan las ciencias, las artes, la literatura solas, en este andar conjunto de la labor creadora. Unas y otras se acompanian, influencian y determinan, como las corrientes de un mismo y prolongado mar. ...

Journal of the American Dietetic Association, 1997

Journal of Medical Case Reports, 2010

Introduction: Erythrodermic psoriasis is a rare generalized clinical presentation of psoriasis in... more Introduction: Erythrodermic psoriasis is a rare generalized clinical presentation of psoriasis in children and adults. Its systemic involvement and a diverse range of clinical findings in the joint and nails are commonly described. A high index of suspicion and an exhaustive differential diagnosis involving other causes of erythroderma should be initially considered. Case presentation: We present the case of a 9-year-old native Hispanic girl with severe erythrodermic psoriasis associated with uncommon advanced nail and joint manifestations. Our patient showed an excellent response to methotrexate medication. Conclusion: This case shows clinical features not commonly described or reported in severe cases of erythrodermic psoriasis, including severe and rare nail and arthritic findings in a pediatric scenario.

International Journal of Infectious Diseases, 2009

International Journal of Infectious Diseases, 2008

A previously healthy, immunocompetent 24-month-old girl was admitted to the Department of Infecto... more A previously healthy, immunocompetent 24-month-old girl was admitted to the Department of Infectology with a 4-day history of painful pruritic blisters that had begun on her right hand. The lesion had spread rapidly to the right forearm, arm, and upper right region of her back. The mother had varicella infection during her third trimester of pregnancy without apparent sequelae in the newborn. The patient was afebrile and had a vesicular rash involving the C7 to D1 dermatomes, with confluent, plaque-like lesions in the upper right zone of the back. The base of a vesicle was scraped and was positive for multinucleated Tzanck cells on microscopic examination (Figure 1). Oral acyclovir was given for 15 days without any complication. The pain, pruritus, and rash were completely resolved within two weeks after treatment without complications. Herpes zoster is uncommon in childhood. Of all patients with zoster, fewer than 10% are younger than 20 years, and 5% are younger than 15 years. 1 Although zoster is primarily a

Gaceta Médica Boliviana

El síndrome de Cook fue descrito por primera vez por Cook y colaboradores en 1985. Este se caract... more El síndrome de Cook fue descrito por primera vez por Cook y colaboradores en 1985. Este se caracteriza por una historia familiar de hipoplasia congénita de las uñas de las manos en los dígitos 1,2 y 3, ausencia de las uñas en los dígitos 4 y 5, braquidactilia del digito 5 de las manos y ausencia complete de las uñas de los pies. Además, puede existir una hipoplasia o ausencia de las falanges distales en los pies y las manos. La oficina de enfermedades raras del Instituto Nacional de Salud, considera este síndrome como una “enfermedad rara”. Presentamos el caso de un recién nacido con anoniquia congénita en ambas manos y pies en el digito 2 asociado a hipoplasia ungueal en dígitos 1 y 3 respetando dígitos 4 y 5. La radiografía de los dedos no muestra anormalidades en las falanges. Este caso podría representar una variante del síndrome de Cook o una nueva enfermedad aun no descrita debido a la existencia de una historia familiar importante con similares deformidades en la madre, la ab...

Pediatrics International, 2020

Revista Peruana De Quimica E Ingenieria Quimica, 2007

El objetivo del trabajo es mostrar el uso del sulfaio de cobre para obtener alcohol deshidratado ... more El objetivo del trabajo es mostrar el uso del sulfaio de cobre para obtener alcohol deshidratado a partir de alcohol rectificado industrial de 96º G. L. El tiempo requerido para la deshidratación total del alcohol fue de 60 minutos. La pureza del alcohol deshidratado se comprobó por la medición de su indice de refracción y por comparación con un patrón MERCK y 100 G.L. a 24ºC.

Quiero agradecer a Dios por brindarme la oportunidad de asumir un nuevo reto en mi vida y cumplir... more Quiero agradecer a Dios por brindarme la oportunidad de asumir un nuevo reto en mi vida y cumplirlo. A Xavier Castellanos porque sin su ayuda y apoyo este trabajo no hubiera sido posible, a Adriana por su amor y apoyo incondicional en todo momento y finalmente a mis compañeros, Melissa, Diego, Johann y Edison quienes también fueron pilar fundamental para la obtención de esta meta. iv DEDICATORIA Quiero dedicar este trabajo a mi familia, padres y hermanos que siempre me han brindado su apoyo incondicional en todo momento, ayudándome a ser la persona que soy. v RESUMEN Este documento tiene por objetivo presentar el desarrollo de un plan de negocios de acuerdo a un análisis de viabilidad financiera para el "Edificio Urbano 4" que es un proyecto inmobiliario ubicado en la zona norte de la ciudad de Quito en el sector de San Isidro del Inca, cuyos promotores y constructores son Flores-Gordillo Arquitectos, profesionales independientes con experiencia en el sector de la construcción y planificación de obra, en especial de proyectos habitacionales. El proyecto se desarrolla en un área de terreno de 787,50 m², con un total de 18 departamentos de 2 y 3 dormitorios desde 59 m² hasta 119 m² clasificados en 10 departamentos de 2 dormitorios y 8 departamentos de 3 dormitorios, 18 parqueaderos en subsuelo y 2 exteriores, área comunal abierta y cerrada en planta baja y áreas exclusivas y comunales abiertas en terraza, con un total de 2.600 m² en áreas construidas y 770 m² en áreas abiertas. El perfil del cliente está conformado por personas y familias de un Nivel Socio Económico (NSE) medio y medio alto con un ingreso promedio familiar entre $ 2000 USD a $ 2500 USD. El análisis financiero del proyecto da como resultado que el mismo es viable y rentable para los promotores, considerando una tasa de descuento del 20%, el margen de utilidad es del 21% con un VAN positivo de $141.643 USD, en un ciclo de vida del proyecto de 18 meses. El proyecto presenta un bajo riesgo en cuanto a factores externos, debido a la alta flexibilidad que presenta al aumento de los costos de construcción a la baja de los precios de venta y a la disminución de la velocidad de ventas vi ABSTRACT This document has as an objective to present the development of a business plan according to a financial viability analysis for the "Edificio Urbano 4" Project. This is a real estate project located in the North side of the city of Quito in the San Isidro del Inca sector, which is promoted and constructed by Flores-Gordillo Arquitectos, independent professionals with experience in building planning and

BMJ case reports, Jan 3, 2014

American Journal of Gastroenterology, 2000

Thrombocytopenia or leukopenia in patients with chronic liver disease is often attributed to func... more Thrombocytopenia or leukopenia in patients with chronic liver disease is often attributed to functional overactivity of the spleen (hypersplenism). Despite being a fairly common phenomenon, there is a paucity of reports on the prevalence of this syndrome in stable chronic liver disease patients with or without severe fibrosis/cirrhosis. The aim of this study was to establish the prevalence of peripheral blood cytopenia in patients with nonalcoholic cirrhosis/severe fibrosis versus patients with mild or no fibrosis on liver biopsy. This is a retrospective chart review of 235 patients who underwent a liver biopsy. One hundred ninety-one patients met strict criteria for study entry; 28 different clinical and laboratory variables were collected from their charts review, and data were then analyzed using the SPSS statistical package. Of the cirrhotic patients, 64% were noted to have platelet counts consistently below 150,000 (lower limit of normal in our laboratory; mean, 144.6 +/- 89.4; median, 114), whereas only 5.5% of noncirrhotic patients had thrombocytopenia (mean, 252.2 +/- 103.4; median, 238). Leukopenia (WBC, <3,500) was relatively rare in the cirrhotic/fibrotic group, having a prevalence of 5% (7.59 +/- 4.3) versus 3.3% (10.62 +/- 14.2) of noncirrhotic patients. Of the patients with cirrhosis, 64% had thrombocytopenia (platelet count, <150,000). The likelihood ratio of finding a platelet count of <100,000 in patients with cirrhosis, as opposed to patients without cirrhosis, is almost 12.

Community-acquired methicillin-resistant Staphylococcus aureus has become a wellestablished patho... more Community-acquired methicillin-resistant Staphylococcus aureus has become a wellestablished pathogen with alarming rates during the last decade. The current situation of this bacteria in pediatric infections is very limited and motivated us to conduct this study. This is a retrospective and analytical study including patients less than 18 years of age with the diagnosis of skin or soft tissue infections in 2008 and 2009 meeting the criteria of Community-acquired infection. A prevalence of 41.9% among skin and soft tissue infections was found. Inducible resistance to clindamycin was detected in 1.3% of the strains and the infection shows a seasonal predilection for summer (P=0.003); 57.8% of the cases required hospitalization with a mean stay of 3.3±2.5 days. The susceptibility to clindamycin and co-trimoxazole is 88 and 97% respectively. The resistance to erythromycin has reached 92%. The main diagnoses at presentation was gluteal abscess plus cellulitis (34.2%). The prevalence of CA-MRSA is trending up and seems to become a large burden for the health system in our community. Clindamycin is still an excellent option in the community setting since inducible clindamycin resistance is extremely low in this community. Co-trimoxazole should be kept as a reserved drug to avoid the rapid resurgence resistance in the community.

Clinics and Practice, 2011

Silver nitrate is commonly recognized for the toxic effects followed by the direct contact with t... more Silver nitrate is commonly recognized for the toxic effects followed by the direct contact with the skin and mucosa known as argyria, but there is surprisingly little information about the adverse effects of silver nitrate after ingestion. Since only a few cases were reported in the literature, the aim of this case is to enrich the little experience existent about the possible effects of silver nitrate ingestion. We describe the case of a 15-year-old female who intentionally ingested 15cc of silver nitrate solution in a suicidal attempt. The clinical picture included an excruciating burning sensation in her throat and nostrils followed by vomiting and poor oral intake. The presence of a whitish membrane on the oral and buccal mucosa without bleeding or erosions was the only remarkable finding at physical examination. Unlike the rest of the cases described in the literature the clinical and endoscopic follow up of the patient was benign and without sequela or signs of oesophageal dam...

Pediatrics International, 2012

Pediatric emergency care, 2012

The aim of this study was to analyze the value of performing laboratory tests, taking cultures, a... more The aim of this study was to analyze the value of performing laboratory tests, taking cultures, and imaging, a diagnostic approach for febrile seizures (FSs) still routinely performed despite the American Academy of Pediatrics recommendations not to. Another aim of this study was to identify the most common sources of fever in patients with FSs and to determine whether the occurrence of FSs correlates with the seasons of the year. This is a retrospective study that included all patients diagnosed with simple or complex FSs who were seen in the emergency room or inpatient unit from January 2004 to December 2009. Of the 219 patients included in the study, 135 (61.4%) cases had the etiology of the FS diagnosed. Upper respiratory tract infection, otitis media, urinary infection, and pneumonia were the most common diagnoses attributed to the fever. Leukocytosis was present in 48 (24%) of 219, and neutrophilia in 199 (91%) of 219 cases. Low bicarbonate levels were common among every age g...

Current Gastroenterology Reports, 1999

Case Reports, 2009

A 15-month-old monozygotic twin infant girl with a history of intrauterine growth retardation was... more A 15-month-old monozygotic twin infant girl with a history of intrauterine growth retardation was admitted to hospital for an acute diarrhoea syndrome. Physical examination revealed asymmetry of the lower and upper limbs for length and width (fig 1A). Other findings included a small triangular face with frontal bossing, lips with downturned corners, micrognathia, and clinodactyly of the fifth finger on both hands (fig …

Clinics and Practice, 2011

Endocarditis is a rare presentation of group B streptococcal infection. Its association with pulm... more Endocarditis is a rare presentation of group B streptococcal infection. Its association with pulmonary septic embolism was only barely studied and limited data is available up to date. Multiple septic emboli is a common complication of bacterial endocarditis, but only a few cases have been documented in relation to group B streptococcus. We present the case of an 87 year old female patient with multiple underlying conditions that predisposed the development of bacterial endocarditis secondary to group B streptococcus and subsequently multiple pulmonary septic emboli. The patient was treated with ceftriaxone and azythromycin with good response and complete recovery without any further complications. In the event of a diagnosed case of group B streptococcus endocarditis, there should be a low threshold for the suspicion of septic pulmonary emboli especially in cases with right valves involvement.

The Modern Language Journal, 1961

Page 1. El Concepto del Espacio en la Literatura NO SE desarrollan las ciencias, las artes, la li... more Page 1. El Concepto del Espacio en la Literatura NO SE desarrollan las ciencias, las artes, la literatura solas, en este andar conjunto de la labor creadora. Unas y otras se acompanian, influencian y determinan, como las corrientes de un mismo y prolongado mar. ...

Journal of the American Dietetic Association, 1997

Journal of Medical Case Reports, 2010

Introduction: Erythrodermic psoriasis is a rare generalized clinical presentation of psoriasis in... more Introduction: Erythrodermic psoriasis is a rare generalized clinical presentation of psoriasis in children and adults. Its systemic involvement and a diverse range of clinical findings in the joint and nails are commonly described. A high index of suspicion and an exhaustive differential diagnosis involving other causes of erythroderma should be initially considered. Case presentation: We present the case of a 9-year-old native Hispanic girl with severe erythrodermic psoriasis associated with uncommon advanced nail and joint manifestations. Our patient showed an excellent response to methotrexate medication. Conclusion: This case shows clinical features not commonly described or reported in severe cases of erythrodermic psoriasis, including severe and rare nail and arthritic findings in a pediatric scenario.

International Journal of Infectious Diseases, 2009

International Journal of Infectious Diseases, 2008

A previously healthy, immunocompetent 24-month-old girl was admitted to the Department of Infecto... more A previously healthy, immunocompetent 24-month-old girl was admitted to the Department of Infectology with a 4-day history of painful pruritic blisters that had begun on her right hand. The lesion had spread rapidly to the right forearm, arm, and upper right region of her back. The mother had varicella infection during her third trimester of pregnancy without apparent sequelae in the newborn. The patient was afebrile and had a vesicular rash involving the C7 to D1 dermatomes, with confluent, plaque-like lesions in the upper right zone of the back. The base of a vesicle was scraped and was positive for multinucleated Tzanck cells on microscopic examination (Figure 1). Oral acyclovir was given for 15 days without any complication. The pain, pruritus, and rash were completely resolved within two weeks after treatment without complications. Herpes zoster is uncommon in childhood. Of all patients with zoster, fewer than 10% are younger than 20 years, and 5% are younger than 15 years. 1 Although zoster is primarily a