Carlos Eduardo Jucá - Academia.edu (original) (raw)
Papers by Carlos Eduardo Jucá
Nucleic Acids Research, 2008
Revista Brasileira De Cirurgia Cardiovascular, 1998
... Josué V. CASTRO NETO*, Rubens J. CARVALHO**, Francisco Carlos C. SOUSA**, Marco Aurélio B. AG... more ... Josué V. CASTRO NETO*, Rubens J. CARVALHO**, Francisco Carlos C. SOUSA**, Marco Aurélio B. AGUIAR**, E. Régis ... 2) , ZUBIATE & KAY (9) , TORRES & DIETL ... Castro Neto JV, Carvalho RJ,Sousa FCC, Aguiar MAB, Jucá ER - Surgical technique decision for the treatment ...
Childs Nervous System, 2006
Background Aplasia cutis congenita (ACC) is a rare disease of unknown etiology, involving any sit... more Background Aplasia cutis congenita (ACC) is a rare disease of unknown etiology, involving any site of the body. The scalp is the most frequent location, followed by the forearms, knees, both sides of the trunk, and neck, in decreasing order of frequency. Superficial lesions may heal spontaneously and seldom result in morbidity or mortality. However, in patients with large scalp and skull defects, there are risks of infection and bleeding. Conservative treatment has been described and advocated, but some authors have highlighted the disadvantages of this treatment modality. On the other hand, several authors claim that aggressive surgical treatment has an important role for large defects. Materials and methods In this paper, we report three newborns with ACC of the scalp, two large defects and a medium one, respectively, treated conservatively and surgically. Conclusion The management of ACC of the scalp is still controversial. Our series suggests that conservative treatment should be performed for initial management in newborns.
Childs Nervous System, 2008
Objective We searched for factors that could predispose towards persistent hydrocephalus in child... more Objective We searched for factors that could predispose towards persistent hydrocephalus in children with posterior fossa (PF) tumors in order to determine the need for permanent cerebrospinal fluid (CSF) diversion. Methods The clinical records of 64 children who underwent surgery for PF tumors in the Pediatric Neurosurgery division of the Hospital of Clinics, Ribeirao Preto, Brazil, from 1990 to 2006, were retrospectively reviewed. The patients’ ages ranged from 3 months to 18 years. The factors evaluated included age at surgery, severity of hydrocephalus (ventricular index), tumor location, size of the tumor, extent of tumor resection, and histology. Results Ventricular index, measured from the initial neuroradiological image, age at surgery, and location of the tumor were significantly associated with definitive postoperative CSF diversion (shunt or endoscopic third ventriculostomy), which was necessary for 34% of the patients. Conclusions Young children with severe preoperative hydrocephalus and a midline tumor should be considered at risk when preoperative treatment decisions are made.
Revista Brasileira De Cirurgia Cardiovascular, 2003
OBJECTIVE: The purpose of our paper was clinical and echocardiographic characterisation of patien... more OBJECTIVE: The purpose of our paper was clinical and echocardiographic characterisation of patients with cardiac tumours and the evaluation of the surgery and tumour recurrence. METHOD: The first part of research was a retrospective investigation to identify cardiac tumours identification and to collect data from patients' records of the Messejana Hospital and Walter Cantídio University Hospital, from 1981 to 2001. In this period, 19 cases of cardiac tumours were discovered. The patients were submitted to clinical, electrocardiographic and echocardiographic re-evaluation from March to July 2002. RESULTS: Congestive symptoms and thoracic pain were the most frequent symptoms. The location in which most of the tumours were identified was left atrium. Among patients submitted to surgery, all of them had the tumour extracted from atrium. The most common histopathologic type was myxoma (78%). Surgical mortality was 14%. Tumour recurrence occurred in one patient. CONCLUSION: Cardiac tumours were more frequent in left atrium, benign tumours were more frequent than malignant tumours, and the most frequent histopathologic type was myxoma.
Psychopharmacology, 2000
Rationale: Electrical or chemical stimulation of some structures of the midbrain tectum, such as ... more Rationale: Electrical or chemical stimulation of some structures of the midbrain tectum, such as the dorsal periaqueductal gray matter, deep layers of the superior colliculus and inferior colliculus induce fear and flight behavior. These structures constitute the main neural substrates commanding defensive behavior in brainstem. Many neurotransmitters are implicated in the modulation of aversion at the mesencephalic level. Objective: The aim of this work is to investigate the involvement of opioid mechanisms in modulation of defensive behavior in dorsal mesencephalon. Methods: Male Wistar rats were fixed in a stereotaxic frame and a chemitrode was implanted into the midbrain, targeted to the central nucleus of the inferior colliculus. In the present study, the effects of peripheral and central administration of naloxone, naltrexone or naloxonazine on aversive thresholds (freezing and escape reactions) elicited by electrical stimulation of the midbrain tectum were determined. Results: Peripherally and centrally administered naloxone caused a significant increase in the freezing and flight thresholds elicited by electrical stimulation of the aversive substrates of the inferior colliculus. These effects were confirmed by peripheral and central administration of naltrexone and by microinjections of naloxonazine in inferior colliculus. Conclusions: These findings suggest that endogenous opioids are involved in the modulation of the aversive behavior elicited by midbrain tectum stimulation. Since microinjections of naloxonazine in the central nucleus of the inferior colliculus caused a significant increase in the aversive thresholds elicited by electrical stimulation of this structure, it is possible that µ1-opioid receptor located in this nucleus may be critically implicated in this neural circuitry.
Journal of Neurosurgery-pediatrics, 2010
tive epilepsy surgery: the multicenter study. Neurology 65:912-918, 2005. 31. Tigaran S, Cascino ... more tive epilepsy surgery: the multicenter study. Neurology 65:912-918, 2005. 31. Tigaran S, Cascino GD, McClelland RL, So EL, Marsh WR: Acute postoperative seizures after frontal lobe cortical resection for intractable partial epilepsy. Ⅲ
Acta Cirurgica Brasileira, 2002
... 1 / 1, LILACS, seleciona. para imprimir. Fotocópia. Texto completo SciELO Brasil. Machado, Hé... more ... 1 / 1, LILACS, seleciona. para imprimir. Fotocópia. Texto completo SciELO Brasil. Machado, Hélio Rubens. experimental, Documentos relacionados. Id: 335020. Autor: Jucá, Carlos Eduardo Barros; Lins Neto, Antônio; Oliveira, Ricardo Santos de; Machado, Hélio Rubens. ...
Introdução -O presente trabalho analisou 150 casos consecutivos de tratamento da hidrocefalia com... more Introdução -O presente trabalho analisou 150 casos consecutivos de tratamento da hidrocefalia com DVP no Hospital das Clínicas de Ribeirão Preto entre março de 1997 e julho de 2000. Objetivo -Traçar as principais características dos pacientes e dos procedimentos, com ênfase nas etiologias, diagnóstico, complicações, seqüelas e fatores associados. Métodos -Prontuários médicos como fonte para quantificar as variáveis selecionadas. Resultados -As etiologias congênitas e adquiridas tiveram a mesma incidência, destacando-se a mielomeningocele no primeiro grupo e a prematuridade e a meningite no segundo. As principais complicações foram o mal funcionamento da válvula (33%) e a infecção (15%). Incluídas as cirurgias devido às complicações, houve 2,5 procedimentos por paciente em média. No último retorno, 40% dos pacientes apresentavam algum grau de retardo do desenvolvimento neuro-psico-motor (RDNPM). As principais etiologias relacionadas a RDNPM foram prematuridade, meningite e malformações complexas. Discussão: O trabalho serviu como ferramenta para ajudar a caracterizar a história natural da hidrocefalia e de seu tratamento em nosso meio, fornecendo base para uma melhor compreensão da mesma e para comparação com a literatura e com outros serviços. A taxa de RDNPM está condizente com a literatura. A taxa de infecção está mais elevada, podendo haver relação com o fato de ser este um hospital-escola. Maior tempo de seguimento seria necessário para comparação da incidência de complicações mecânicas. Disponível em URL: http://www.scielo.br/acb Descritores -Hidrocefalia, Derivação Ventrículo-Peritoneal.
Psychopharmacology, 2000
Rationale: Electrical or chemical stimulation of some structures of the midbrain tectum, such as ... more Rationale: Electrical or chemical stimulation of some structures of the midbrain tectum, such as the dorsal periaqueductal gray matter, deep layers of the superior colliculus and inferior colliculus induce fear and flight behavior. These structures constitute the main neural substrates commanding defensive behavior in brainstem. Many neurotransmitters are implicated in the modulation of aversion at the mesencephalic level. Objective: The aim of this work is to investigate the involvement of opioid mechanisms in modulation of defensive behavior in dorsal mesencephalon. Methods: Male Wistar rats were fixed in a stereotaxic frame and a chemitrode was implanted into the midbrain, targeted to the central nucleus of the inferior colliculus. In the present study, the effects of peripheral and central administration of naloxone, naltrexone or naloxonazine on aversive thresholds (freezing and escape reactions) elicited by electrical stimulation of the midbrain tectum were determined. Results: Peripherally and centrally administered naloxone caused a significant increase in the freezing and flight thresholds elicited by electrical stimulation of the aversive substrates of the inferior colliculus. These effects were confirmed by peripheral and central administration of naltrexone and by microinjections of naloxonazine in inferior colliculus. Conclusions: These findings suggest that endogenous opioids are involved in the modulation of the aversive behavior elicited by midbrain tectum stimulation. Since microinjections of naloxonazine in the central nucleus of the inferior colliculus caused a significant increase in the aversive thresholds elicited by electrical stimulation of this structure, it is possible that µ1-opioid receptor located in this nucleus may be critically implicated in this neural circuitry.
Nucleic Acids Research, 2008
Revista Brasileira De Cirurgia Cardiovascular, 1998
... Josué V. CASTRO NETO*, Rubens J. CARVALHO**, Francisco Carlos C. SOUSA**, Marco Aurélio B. AG... more ... Josué V. CASTRO NETO*, Rubens J. CARVALHO**, Francisco Carlos C. SOUSA**, Marco Aurélio B. AGUIAR**, E. Régis ... 2) , ZUBIATE & KAY (9) , TORRES & DIETL ... Castro Neto JV, Carvalho RJ,Sousa FCC, Aguiar MAB, Jucá ER - Surgical technique decision for the treatment ...
Childs Nervous System, 2006
Background Aplasia cutis congenita (ACC) is a rare disease of unknown etiology, involving any sit... more Background Aplasia cutis congenita (ACC) is a rare disease of unknown etiology, involving any site of the body. The scalp is the most frequent location, followed by the forearms, knees, both sides of the trunk, and neck, in decreasing order of frequency. Superficial lesions may heal spontaneously and seldom result in morbidity or mortality. However, in patients with large scalp and skull defects, there are risks of infection and bleeding. Conservative treatment has been described and advocated, but some authors have highlighted the disadvantages of this treatment modality. On the other hand, several authors claim that aggressive surgical treatment has an important role for large defects. Materials and methods In this paper, we report three newborns with ACC of the scalp, two large defects and a medium one, respectively, treated conservatively and surgically. Conclusion The management of ACC of the scalp is still controversial. Our series suggests that conservative treatment should be performed for initial management in newborns.
Childs Nervous System, 2008
Objective We searched for factors that could predispose towards persistent hydrocephalus in child... more Objective We searched for factors that could predispose towards persistent hydrocephalus in children with posterior fossa (PF) tumors in order to determine the need for permanent cerebrospinal fluid (CSF) diversion. Methods The clinical records of 64 children who underwent surgery for PF tumors in the Pediatric Neurosurgery division of the Hospital of Clinics, Ribeirao Preto, Brazil, from 1990 to 2006, were retrospectively reviewed. The patients’ ages ranged from 3 months to 18 years. The factors evaluated included age at surgery, severity of hydrocephalus (ventricular index), tumor location, size of the tumor, extent of tumor resection, and histology. Results Ventricular index, measured from the initial neuroradiological image, age at surgery, and location of the tumor were significantly associated with definitive postoperative CSF diversion (shunt or endoscopic third ventriculostomy), which was necessary for 34% of the patients. Conclusions Young children with severe preoperative hydrocephalus and a midline tumor should be considered at risk when preoperative treatment decisions are made.
Revista Brasileira De Cirurgia Cardiovascular, 2003
OBJECTIVE: The purpose of our paper was clinical and echocardiographic characterisation of patien... more OBJECTIVE: The purpose of our paper was clinical and echocardiographic characterisation of patients with cardiac tumours and the evaluation of the surgery and tumour recurrence. METHOD: The first part of research was a retrospective investigation to identify cardiac tumours identification and to collect data from patients' records of the Messejana Hospital and Walter Cantídio University Hospital, from 1981 to 2001. In this period, 19 cases of cardiac tumours were discovered. The patients were submitted to clinical, electrocardiographic and echocardiographic re-evaluation from March to July 2002. RESULTS: Congestive symptoms and thoracic pain were the most frequent symptoms. The location in which most of the tumours were identified was left atrium. Among patients submitted to surgery, all of them had the tumour extracted from atrium. The most common histopathologic type was myxoma (78%). Surgical mortality was 14%. Tumour recurrence occurred in one patient. CONCLUSION: Cardiac tumours were more frequent in left atrium, benign tumours were more frequent than malignant tumours, and the most frequent histopathologic type was myxoma.
Psychopharmacology, 2000
Rationale: Electrical or chemical stimulation of some structures of the midbrain tectum, such as ... more Rationale: Electrical or chemical stimulation of some structures of the midbrain tectum, such as the dorsal periaqueductal gray matter, deep layers of the superior colliculus and inferior colliculus induce fear and flight behavior. These structures constitute the main neural substrates commanding defensive behavior in brainstem. Many neurotransmitters are implicated in the modulation of aversion at the mesencephalic level. Objective: The aim of this work is to investigate the involvement of opioid mechanisms in modulation of defensive behavior in dorsal mesencephalon. Methods: Male Wistar rats were fixed in a stereotaxic frame and a chemitrode was implanted into the midbrain, targeted to the central nucleus of the inferior colliculus. In the present study, the effects of peripheral and central administration of naloxone, naltrexone or naloxonazine on aversive thresholds (freezing and escape reactions) elicited by electrical stimulation of the midbrain tectum were determined. Results: Peripherally and centrally administered naloxone caused a significant increase in the freezing and flight thresholds elicited by electrical stimulation of the aversive substrates of the inferior colliculus. These effects were confirmed by peripheral and central administration of naltrexone and by microinjections of naloxonazine in inferior colliculus. Conclusions: These findings suggest that endogenous opioids are involved in the modulation of the aversive behavior elicited by midbrain tectum stimulation. Since microinjections of naloxonazine in the central nucleus of the inferior colliculus caused a significant increase in the aversive thresholds elicited by electrical stimulation of this structure, it is possible that µ1-opioid receptor located in this nucleus may be critically implicated in this neural circuitry.
Journal of Neurosurgery-pediatrics, 2010
tive epilepsy surgery: the multicenter study. Neurology 65:912-918, 2005. 31. Tigaran S, Cascino ... more tive epilepsy surgery: the multicenter study. Neurology 65:912-918, 2005. 31. Tigaran S, Cascino GD, McClelland RL, So EL, Marsh WR: Acute postoperative seizures after frontal lobe cortical resection for intractable partial epilepsy. Ⅲ
Acta Cirurgica Brasileira, 2002
... 1 / 1, LILACS, seleciona. para imprimir. Fotocópia. Texto completo SciELO Brasil. Machado, Hé... more ... 1 / 1, LILACS, seleciona. para imprimir. Fotocópia. Texto completo SciELO Brasil. Machado, Hélio Rubens. experimental, Documentos relacionados. Id: 335020. Autor: Jucá, Carlos Eduardo Barros; Lins Neto, Antônio; Oliveira, Ricardo Santos de; Machado, Hélio Rubens. ...
Introdução -O presente trabalho analisou 150 casos consecutivos de tratamento da hidrocefalia com... more Introdução -O presente trabalho analisou 150 casos consecutivos de tratamento da hidrocefalia com DVP no Hospital das Clínicas de Ribeirão Preto entre março de 1997 e julho de 2000. Objetivo -Traçar as principais características dos pacientes e dos procedimentos, com ênfase nas etiologias, diagnóstico, complicações, seqüelas e fatores associados. Métodos -Prontuários médicos como fonte para quantificar as variáveis selecionadas. Resultados -As etiologias congênitas e adquiridas tiveram a mesma incidência, destacando-se a mielomeningocele no primeiro grupo e a prematuridade e a meningite no segundo. As principais complicações foram o mal funcionamento da válvula (33%) e a infecção (15%). Incluídas as cirurgias devido às complicações, houve 2,5 procedimentos por paciente em média. No último retorno, 40% dos pacientes apresentavam algum grau de retardo do desenvolvimento neuro-psico-motor (RDNPM). As principais etiologias relacionadas a RDNPM foram prematuridade, meningite e malformações complexas. Discussão: O trabalho serviu como ferramenta para ajudar a caracterizar a história natural da hidrocefalia e de seu tratamento em nosso meio, fornecendo base para uma melhor compreensão da mesma e para comparação com a literatura e com outros serviços. A taxa de RDNPM está condizente com a literatura. A taxa de infecção está mais elevada, podendo haver relação com o fato de ser este um hospital-escola. Maior tempo de seguimento seria necessário para comparação da incidência de complicações mecânicas. Disponível em URL: http://www.scielo.br/acb Descritores -Hidrocefalia, Derivação Ventrículo-Peritoneal.
Psychopharmacology, 2000
Rationale: Electrical or chemical stimulation of some structures of the midbrain tectum, such as ... more Rationale: Electrical or chemical stimulation of some structures of the midbrain tectum, such as the dorsal periaqueductal gray matter, deep layers of the superior colliculus and inferior colliculus induce fear and flight behavior. These structures constitute the main neural substrates commanding defensive behavior in brainstem. Many neurotransmitters are implicated in the modulation of aversion at the mesencephalic level. Objective: The aim of this work is to investigate the involvement of opioid mechanisms in modulation of defensive behavior in dorsal mesencephalon. Methods: Male Wistar rats were fixed in a stereotaxic frame and a chemitrode was implanted into the midbrain, targeted to the central nucleus of the inferior colliculus. In the present study, the effects of peripheral and central administration of naloxone, naltrexone or naloxonazine on aversive thresholds (freezing and escape reactions) elicited by electrical stimulation of the midbrain tectum were determined. Results: Peripherally and centrally administered naloxone caused a significant increase in the freezing and flight thresholds elicited by electrical stimulation of the aversive substrates of the inferior colliculus. These effects were confirmed by peripheral and central administration of naltrexone and by microinjections of naloxonazine in inferior colliculus. Conclusions: These findings suggest that endogenous opioids are involved in the modulation of the aversive behavior elicited by midbrain tectum stimulation. Since microinjections of naloxonazine in the central nucleus of the inferior colliculus caused a significant increase in the aversive thresholds elicited by electrical stimulation of this structure, it is possible that µ1-opioid receptor located in this nucleus may be critically implicated in this neural circuitry.