Cedric Delhaye - Academia.edu (original) (raw)
Papers by Cedric Delhaye
Archives of cardiovascular diseases
Hybrid revascularization, comprising coronary artery bypass graft with exclusive arterial conduit... more Hybrid revascularization, comprising coronary artery bypass graft with exclusive arterial conduits followed by early drug-eluting stent implantation, in multivessel coronary artery disease Revascularisation coronaire hybride combinant pontage « exclusivement artériel » et implantation précoce de stent actif chez les patients multi-tronculaires Summary Aim. -To assess the feasibility and safety of a hybrid myocardial revascularization strategy combining ''exclusive arterial'' conventional coronary artery bypass grafting (CABG) followed by early drug-eluting stent (DES) implantation in multivessel coronary artery disease (CAD). Methods. -Eighteen consecutive patients with multivessel CAD were enrolled prospectively. Within 48 hours of CABG using left internal mammary artery (IMA) to left anterior descending (LAD) coronary artery with or without right IMA to non-LAD vessel in an open chest approach, DESs were implanted systematically in an additional vessel after a clopidogrel 300-mg preloading Abbreviations: CABG, coronary artery bypass graft; CAD, coronary artery disease; DES, drug-eluting stent; IMA, internal mammary artery; LAD, left anterior descending; MIDCAB, minimally invasive direct coronary artery bypass; PCI, percutaneous coronary intervention; RE-MIDCAB, robotically enhanced minimally invasive direct coronary artery bypass; VG, vein graft; RCA, right coronary artery; CPB, cardiopulmonary bypass; MACE, major adverse cardiac events; MI, myocardial infarction; TVR, target vessel revascularization; CK, creatinine kinase; ULN, upper limit of normal; TIMI, thrombolysis in myocardial infarction.
International journal of cardiology, Jan 30, 2014
The Annals of thoracic surgery, 2012
Background. In some patients, transfemoral, transaxillary, or transapical aortic valve implantati... more Background. In some patients, transfemoral, transaxillary, or transapical aortic valve implantation is not possible. Thus, carotid artery access may represent a safe alternative to those accesses, and even offers certain advantages. In this article, we describe aortic valve implantation using the left carotid arterial approach and report our initial experience.
Journal of cardiac surgery, 2014
Transcatheter aortic valve implantation (TAVI) is still under active investigation. When the femo... more Transcatheter aortic valve implantation (TAVI) is still under active investigation. When the femoral route is impossible for anatomic reasons, the transapical, transaxillary and direct aortic approaches have demonstrated their effectiveness. We report the successful implantation of a Sapien XT bioprosthesis with the NovaFlex catheter through a left carotid approach.
Catheterization and Cardiovascular Interventions
Objectives: We attempted to investigate incidence and predictors of recurrent in stent thrombosis... more Objectives: We attempted to investigate incidence and predictors of recurrent in stent thrombosis (IST) after successful treatment of a first IST. Background: The occurrence of recurrent IST after successful treatment of a first IST may be a decisive factor for patient clinical outcome. However, incidence and predictors of recurrent IST are currently poorly described in the literature. Methods: Between 2003 and 2005, 2,190 patients underwent a percutaneous coronary intervention in our center. During a median follow-up of 19.4 months, 49 patients (2.24%) presented a first definite IST. Patients presenting with a first IST were followed during an additional median period of 40 months. Their baseline characteristics were listed and cardiovascular events especially recurrent IST as defined by the Academic Research Consortium definition were systematically indexed. Results: Altogether 39 (80%) patients were successfully treated with an effective reperfusion after percutaneous coronary intervention. Fourteen (36%) patients presented a recurrent IST and three presented multiple recurrent IST. The median occurrence time of recurrent IST was 5 days, range between 1 and 11 days. Multivariate analysis identified history of neoplasia (HR 5 11.53, 95% CI 2.32-57.37, P 5 0.003), residual diameter stenosis (HR 5 1.15, 95% CI 1.02-1.29, P 5 0.02), and residual dissection after treatment (HR 5 8.78, 95% CI 1.85-41.62, P 5 0.006), as independent predictors of recurrent IST. Conclusion: Recurrent IST is a frequent and early event after successful treatment of a first IST. Our results suggest that mechanical factors like residual dissection and residual diameter stenosis should be carefully tracked down. In addition, patients with multiple recurrent IST and the early time course of recurrent IST also suggest a potential role of inadequate antiplatelet therapy. '
Cardiovascular revascularization medicine: including molecular interventions
Corevalve dislocation has been reported to significantly increase the perioperative risk for seve... more Corevalve dislocation has been reported to significantly increase the perioperative risk for severe complications and poor outcomes. We describe the case of an 87-year-old man who was referred to our center for transcatheter aortic valve implantation and who experienced an original complication after Corevalve dislocation by subclavian approach. Indeed, during the attempt to retrieve the partially expanded and dislocated valve through the subclavian introducer sheath, we experienced a dislodgment of the valve from the housing sheath that led to a delivery catheter cone separation and systemic embolization.
Archives of Cardiovascular Diseases Supplements
International journal of cardiology
The Annals of Thoracic Surgery, 2012
Background. In some patients, transfemoral, transaxillary, or transapical aortic valve implantati... more Background. In some patients, transfemoral, transaxillary, or transapical aortic valve implantation is not possible. Thus, carotid artery access may represent a safe alternative to those accesses, and even offers certain advantages. In this article, we describe aortic valve implantation using the left carotid arterial approach and report our initial experience.
Archives of cardiovascular diseases
Hybrid revascularization, comprising coronary artery bypass graft with exclusive arterial conduit... more Hybrid revascularization, comprising coronary artery bypass graft with exclusive arterial conduits followed by early drug-eluting stent implantation, in multivessel coronary artery disease Revascularisation coronaire hybride combinant pontage « exclusivement artériel » et implantation précoce de stent actif chez les patients multi-tronculaires Summary Aim. -To assess the feasibility and safety of a hybrid myocardial revascularization strategy combining ''exclusive arterial'' conventional coronary artery bypass grafting (CABG) followed by early drug-eluting stent (DES) implantation in multivessel coronary artery disease (CAD). Methods. -Eighteen consecutive patients with multivessel CAD were enrolled prospectively. Within 48 hours of CABG using left internal mammary artery (IMA) to left anterior descending (LAD) coronary artery with or without right IMA to non-LAD vessel in an open chest approach, DESs were implanted systematically in an additional vessel after a clopidogrel 300-mg preloading Abbreviations: CABG, coronary artery bypass graft; CAD, coronary artery disease; DES, drug-eluting stent; IMA, internal mammary artery; LAD, left anterior descending; MIDCAB, minimally invasive direct coronary artery bypass; PCI, percutaneous coronary intervention; RE-MIDCAB, robotically enhanced minimally invasive direct coronary artery bypass; VG, vein graft; RCA, right coronary artery; CPB, cardiopulmonary bypass; MACE, major adverse cardiac events; MI, myocardial infarction; TVR, target vessel revascularization; CK, creatinine kinase; ULN, upper limit of normal; TIMI, thrombolysis in myocardial infarction.
International journal of cardiology, Jan 30, 2014
The Annals of thoracic surgery, 2012
Background. In some patients, transfemoral, transaxillary, or transapical aortic valve implantati... more Background. In some patients, transfemoral, transaxillary, or transapical aortic valve implantation is not possible. Thus, carotid artery access may represent a safe alternative to those accesses, and even offers certain advantages. In this article, we describe aortic valve implantation using the left carotid arterial approach and report our initial experience.
Journal of cardiac surgery, 2014
Transcatheter aortic valve implantation (TAVI) is still under active investigation. When the femo... more Transcatheter aortic valve implantation (TAVI) is still under active investigation. When the femoral route is impossible for anatomic reasons, the transapical, transaxillary and direct aortic approaches have demonstrated their effectiveness. We report the successful implantation of a Sapien XT bioprosthesis with the NovaFlex catheter through a left carotid approach.
Catheterization and Cardiovascular Interventions
Objectives: We attempted to investigate incidence and predictors of recurrent in stent thrombosis... more Objectives: We attempted to investigate incidence and predictors of recurrent in stent thrombosis (IST) after successful treatment of a first IST. Background: The occurrence of recurrent IST after successful treatment of a first IST may be a decisive factor for patient clinical outcome. However, incidence and predictors of recurrent IST are currently poorly described in the literature. Methods: Between 2003 and 2005, 2,190 patients underwent a percutaneous coronary intervention in our center. During a median follow-up of 19.4 months, 49 patients (2.24%) presented a first definite IST. Patients presenting with a first IST were followed during an additional median period of 40 months. Their baseline characteristics were listed and cardiovascular events especially recurrent IST as defined by the Academic Research Consortium definition were systematically indexed. Results: Altogether 39 (80%) patients were successfully treated with an effective reperfusion after percutaneous coronary intervention. Fourteen (36%) patients presented a recurrent IST and three presented multiple recurrent IST. The median occurrence time of recurrent IST was 5 days, range between 1 and 11 days. Multivariate analysis identified history of neoplasia (HR 5 11.53, 95% CI 2.32-57.37, P 5 0.003), residual diameter stenosis (HR 5 1.15, 95% CI 1.02-1.29, P 5 0.02), and residual dissection after treatment (HR 5 8.78, 95% CI 1.85-41.62, P 5 0.006), as independent predictors of recurrent IST. Conclusion: Recurrent IST is a frequent and early event after successful treatment of a first IST. Our results suggest that mechanical factors like residual dissection and residual diameter stenosis should be carefully tracked down. In addition, patients with multiple recurrent IST and the early time course of recurrent IST also suggest a potential role of inadequate antiplatelet therapy. '
Cardiovascular revascularization medicine: including molecular interventions
Corevalve dislocation has been reported to significantly increase the perioperative risk for seve... more Corevalve dislocation has been reported to significantly increase the perioperative risk for severe complications and poor outcomes. We describe the case of an 87-year-old man who was referred to our center for transcatheter aortic valve implantation and who experienced an original complication after Corevalve dislocation by subclavian approach. Indeed, during the attempt to retrieve the partially expanded and dislocated valve through the subclavian introducer sheath, we experienced a dislodgment of the valve from the housing sheath that led to a delivery catheter cone separation and systemic embolization.
Archives of Cardiovascular Diseases Supplements
International journal of cardiology
The Annals of Thoracic Surgery, 2012
Background. In some patients, transfemoral, transaxillary, or transapical aortic valve implantati... more Background. In some patients, transfemoral, transaxillary, or transapical aortic valve implantation is not possible. Thus, carotid artery access may represent a safe alternative to those accesses, and even offers certain advantages. In this article, we describe aortic valve implantation using the left carotid arterial approach and report our initial experience.