Chand Ali - Academia.edu (original) (raw)
Papers by Chand Ali
Talanta, 2020
Nitrogendoping to enhance the separation selectivity of glucose-based carbon dots-modified silica... more Nitrogendoping to enhance the separation selectivity of glucose-based carbon dots-modified silica stationary phase for hydrophilic interaction chromatography, Talanta (2020), doi: https://doi.org/10.1016/ j.talanta.2020.121140. This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.
Microchimica Acta, 2020
Cadmium cobaltite (CdCo 2 O 4) nanosheets were ultra-fast synthesized based on a new basic deep e... more Cadmium cobaltite (CdCo 2 O 4) nanosheets were ultra-fast synthesized based on a new basic deep eutectic solvent (DES) which served simultaneously as reactant, solvents, and template. Interestingly, the nanosheets were found to exhibit triple-enzyme mimetic activities including oxidase-like activity, peroxidase-like activity, and catalase-like activity. Their catalytic activity followed the typical Michaelis-Menten kinetics, and high affinity for H 2 O 2 and TMB was observed. Based on the superior peroxidase-like catalytic activity of CdCo 2 O 4 nanosheets, a highly sensitive and selective colorimetric strategy for the determination of glucose was established. Under optimized conditions, the absorbance at 652 nm increases linearly in the 0.5 to 100 μM concentration range, and the limit of detection is 0.13 μM (S/N = 3). Finally, the method was successfully used for determination of glucose in serum samples.
Sensors and Actuators B: Chemical, 2019
This is a PDF file of an article that has undergone enhancements after acceptance, such as the ad... more This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.
Chinese Chemical Letters, 2019
Basic deep eutectic solvents as reactant, template and solvents for ultra-fast preparation of tra... more Basic deep eutectic solvents as reactant, template and solvents for ultra-fast preparation of transition metal oxide nanomaterials,
Talanta, 2019
Effective extraction of flavonoids from Lycium barbarum L. fruits by deep eutectic solvents-based... more Effective extraction of flavonoids from Lycium barbarum L. fruits by deep eutectic solvents-based ultrasound-assisted extraction, Talanta (2019), doi:
Sensors and Actuators B: Chemical, 2019
Highlights NPG/Cu2O nanocomposite was firstly prepared via combustion-reduction method. NPG/C... more Highlights NPG/Cu2O nanocomposite was firstly prepared via combustion-reduction method. NPG/Cu2O nanocomposite exhibited strong catalytic activity. A chemiluminescence sensing platform was firstly constructed for the determination of NADH. The proposed sensor was used to monitor NADH from human serum and lung cancer A549 cell lysates.
Chinese Chemical Letters, 2019
Abstract Here we firstly report a series of new deep eutectic solvents (DESs) induced by small am... more Abstract Here we firstly report a series of new deep eutectic solvents (DESs) induced by small amounts of crown ether complex and mainly formed by polyethylene glycol. These DESs not only presented the ultra-deep extraction of non-basic N-compounds from fuel oils, but also opened up the possibility of other new applications in chemistry and materials science.
Reviews in Chemical Engineering, 2019
In China, the rapid development greatly promotes the national economic power and living standard ... more In China, the rapid development greatly promotes the national economic power and living standard but also inevitably brings a series of environmental problems. In order to resolve these problems fundamentally, Chinese scientists have been undertaking research in the area of green chemical engineering (GCE) for many years and achieved great progresses. In this paper, we reviewed the research progresses related to GCE in China and screened four typical topics related to the Chinese resources characteristics and environmental requirements, i.e. ionic liquids and their applications, biomass utilization and bio-based materials/products, green solvent-mediated extraction technologies, and cold plasmas for coal conversion. Afterwards, the perspectives and development tendencies of GCE were proposed, and the challenges which will be faced while developing available industrial technologies in China were mentioned.
Macromolecules, 2018
In this study, we reported a method to prepare a lignin based cryogel by cross-linking deep eutec... more In this study, we reported a method to prepare a lignin based cryogel by cross-linking deep eutectic solvent (DES) extracted lignin and formaldehyde as an alternative to replace resorcinol-formaldehyde (RF) based aerogel. The resulting lignin-formaldehyde cryogel has a highly porous structure (172.8 m 2 /g surface area) with a high dimension stability. We found that the hydroxyl group and carbonyl group of DES lignin provide reactive sites to cross-link with formaldehyde through electrophilic addition and aldol condensation reaction. We also found that using choline chloridelactic acid (ChCl-Lac) DES as a solvent during the lignin-formaldehyde cryogel formation is critical to prevent the shrinkage of the final cyrogel. The ensuing lignin-formaldehyde cryogel has promising properties such as high thermostability, low thermal conductivity, and good fire retardancy.
Advanced Functional Materials, 2018
Porous graphene membranes hold great promise for high-selectivity separation. Moreover, their pra... more Porous graphene membranes hold great promise for high-selectivity separation. Moreover, their practical application is limited by the lack of a simple and efficient method for the synthesis of porous graphene. Here, a rapid and scalable method is developed for the synthesis of porous graphene via partial combustion of graphene oxide imperfectly covered by hydrotalcite. This method is not only less energy-and time-intensive than existing ones, but also allows precise control of pore size. Remarkably, the resulting membrane of porous graphene exhibits high selectivity for K + and Na + (α = 3.84) separation. Hence, this facile route for preparing membranes of porous graphene oxide might direct application membranes in environmental, energy, desalination, and biomedical fields.
Nanoscale, Jan 6, 2018
As an important biomarker for the early stage of apoptosis, cytochrome c (Cyt c) has been recogni... more As an important biomarker for the early stage of apoptosis, cytochrome c (Cyt c) has been recognized as a key component of the intrinsic apoptotic pathway. Fluorescence imaging tools enabling detection of Cyt c in apoptotic signaling have been rarely explored, though they are critical for cell biology and clinical theranostics. Here, we designed a novel label-free N-doped carbon dot (N-doped CD)-based nanosensor that enables fluorescence activation imaging of Cyt c release in cell apoptosis. The inner filter effect of Cyt c towards N-doped CDs enabled quantitative Cyt c measurement. The nanosensor exhibited high sensitivity and selectivity, rapid response, good cell-membrane permeability and low cytotoxicity. All these features are favorable for in situ visualization of Cyt c for apoptosis research. Notably, the developed nanosensor was successfully applied to monitor intracellular release of Cyt c, and to visualize Cyt c in living zebrafish for the first time. Moreover, it also pro...
ChemSusChem, Sep 13, 2017
The serious environmental problems of modern society creates a great demand for the efficient upt... more The serious environmental problems of modern society creates a great demand for the efficient uptake of NH₃ by solvents. However, many shortcomings exist with the traditional aqueous absorbents, and efforts to use ionic liquids met limited success. In this work, we for the first time report that the design of hybrid deep eutectic solvents (DESs) with flexible hydrogen-bonded supramolecular network enabled both exceptional NH₃ uptake capacity and superior desorption-regeneration performance, along with superb NH₃/CO₂ selectivity and environmental merits. Elucidated by the molecular dynamic simulations and spectrum analysis, the abundant hydrogen-bonding sites in the hybrid DESs grasp the every atom of NH₃ molecule and enable a strong physical reversible solvation, while the multiple interactions among the hybrid components create a flexible hydrogen-bonded supramolecular network and allow for solvent-unbreaking absorption to ensure the full participation of solvent and process stabil...
Advanced healthcare materials, Jan 31, 2017
Graphene oxides (GO) are attracting much attention in the diagnosis and therapy of the subcutaneo... more Graphene oxides (GO) are attracting much attention in the diagnosis and therapy of the subcutaneous tumor as a novel biomaterial, but its diagnosis to tissue dysfunction is yet to be found. Here, a novel application of GO for diagnosis of renal dysfunction via contrast-enhanced computed tomography (CT) is proposed. In order to serve as contrast-enhanced agent, Ag nanoparticles (AgNPs) are composited on the surface of GO to promote its X-ray absorption, and then simvastatin is coinjected for eliminating in vivo toxicity induced by AgNPs. It is found that GO/AgNPs can enhance the imaging of CT into the lung, liver, and kidney of mice for a long circulation time (≈24 h) and a safety profile in vivo in the presence of simvastatin. Interestingly, the lower dose of GO/AgNPs (≈0.5 mg per kg bw) shows an excellent performance for CT imaging of renal perfusion, and visually exhibits the right renal dysfunction in model mice. Hence, this work suggests that graphene nanoparticles will play a v...
Green Chemistry, 2016
Both basic and non-basic nitrogen compounds can be efficiently removed from fuels by deep eutecti... more Both basic and non-basic nitrogen compounds can be efficiently removed from fuels by deep eutectic solvents.
Talanta, 2020
Nitrogendoping to enhance the separation selectivity of glucose-based carbon dots-modified silica... more Nitrogendoping to enhance the separation selectivity of glucose-based carbon dots-modified silica stationary phase for hydrophilic interaction chromatography, Talanta (2020), doi: https://doi.org/10.1016/ j.talanta.2020.121140. This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.
Microchimica Acta, 2020
Cadmium cobaltite (CdCo 2 O 4) nanosheets were ultra-fast synthesized based on a new basic deep e... more Cadmium cobaltite (CdCo 2 O 4) nanosheets were ultra-fast synthesized based on a new basic deep eutectic solvent (DES) which served simultaneously as reactant, solvents, and template. Interestingly, the nanosheets were found to exhibit triple-enzyme mimetic activities including oxidase-like activity, peroxidase-like activity, and catalase-like activity. Their catalytic activity followed the typical Michaelis-Menten kinetics, and high affinity for H 2 O 2 and TMB was observed. Based on the superior peroxidase-like catalytic activity of CdCo 2 O 4 nanosheets, a highly sensitive and selective colorimetric strategy for the determination of glucose was established. Under optimized conditions, the absorbance at 652 nm increases linearly in the 0.5 to 100 μM concentration range, and the limit of detection is 0.13 μM (S/N = 3). Finally, the method was successfully used for determination of glucose in serum samples.
Sensors and Actuators B: Chemical, 2019
This is a PDF file of an article that has undergone enhancements after acceptance, such as the ad... more This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.
Chinese Chemical Letters, 2019
Basic deep eutectic solvents as reactant, template and solvents for ultra-fast preparation of tra... more Basic deep eutectic solvents as reactant, template and solvents for ultra-fast preparation of transition metal oxide nanomaterials,
Talanta, 2019
Effective extraction of flavonoids from Lycium barbarum L. fruits by deep eutectic solvents-based... more Effective extraction of flavonoids from Lycium barbarum L. fruits by deep eutectic solvents-based ultrasound-assisted extraction, Talanta (2019), doi:
Sensors and Actuators B: Chemical, 2019
Highlights NPG/Cu2O nanocomposite was firstly prepared via combustion-reduction method. NPG/C... more Highlights NPG/Cu2O nanocomposite was firstly prepared via combustion-reduction method. NPG/Cu2O nanocomposite exhibited strong catalytic activity. A chemiluminescence sensing platform was firstly constructed for the determination of NADH. The proposed sensor was used to monitor NADH from human serum and lung cancer A549 cell lysates.
Chinese Chemical Letters, 2019
Abstract Here we firstly report a series of new deep eutectic solvents (DESs) induced by small am... more Abstract Here we firstly report a series of new deep eutectic solvents (DESs) induced by small amounts of crown ether complex and mainly formed by polyethylene glycol. These DESs not only presented the ultra-deep extraction of non-basic N-compounds from fuel oils, but also opened up the possibility of other new applications in chemistry and materials science.
Reviews in Chemical Engineering, 2019
In China, the rapid development greatly promotes the national economic power and living standard ... more In China, the rapid development greatly promotes the national economic power and living standard but also inevitably brings a series of environmental problems. In order to resolve these problems fundamentally, Chinese scientists have been undertaking research in the area of green chemical engineering (GCE) for many years and achieved great progresses. In this paper, we reviewed the research progresses related to GCE in China and screened four typical topics related to the Chinese resources characteristics and environmental requirements, i.e. ionic liquids and their applications, biomass utilization and bio-based materials/products, green solvent-mediated extraction technologies, and cold plasmas for coal conversion. Afterwards, the perspectives and development tendencies of GCE were proposed, and the challenges which will be faced while developing available industrial technologies in China were mentioned.
Macromolecules, 2018
In this study, we reported a method to prepare a lignin based cryogel by cross-linking deep eutec... more In this study, we reported a method to prepare a lignin based cryogel by cross-linking deep eutectic solvent (DES) extracted lignin and formaldehyde as an alternative to replace resorcinol-formaldehyde (RF) based aerogel. The resulting lignin-formaldehyde cryogel has a highly porous structure (172.8 m 2 /g surface area) with a high dimension stability. We found that the hydroxyl group and carbonyl group of DES lignin provide reactive sites to cross-link with formaldehyde through electrophilic addition and aldol condensation reaction. We also found that using choline chloridelactic acid (ChCl-Lac) DES as a solvent during the lignin-formaldehyde cryogel formation is critical to prevent the shrinkage of the final cyrogel. The ensuing lignin-formaldehyde cryogel has promising properties such as high thermostability, low thermal conductivity, and good fire retardancy.
Advanced Functional Materials, 2018
Porous graphene membranes hold great promise for high-selectivity separation. Moreover, their pra... more Porous graphene membranes hold great promise for high-selectivity separation. Moreover, their practical application is limited by the lack of a simple and efficient method for the synthesis of porous graphene. Here, a rapid and scalable method is developed for the synthesis of porous graphene via partial combustion of graphene oxide imperfectly covered by hydrotalcite. This method is not only less energy-and time-intensive than existing ones, but also allows precise control of pore size. Remarkably, the resulting membrane of porous graphene exhibits high selectivity for K + and Na + (α = 3.84) separation. Hence, this facile route for preparing membranes of porous graphene oxide might direct application membranes in environmental, energy, desalination, and biomedical fields.
Nanoscale, Jan 6, 2018
As an important biomarker for the early stage of apoptosis, cytochrome c (Cyt c) has been recogni... more As an important biomarker for the early stage of apoptosis, cytochrome c (Cyt c) has been recognized as a key component of the intrinsic apoptotic pathway. Fluorescence imaging tools enabling detection of Cyt c in apoptotic signaling have been rarely explored, though they are critical for cell biology and clinical theranostics. Here, we designed a novel label-free N-doped carbon dot (N-doped CD)-based nanosensor that enables fluorescence activation imaging of Cyt c release in cell apoptosis. The inner filter effect of Cyt c towards N-doped CDs enabled quantitative Cyt c measurement. The nanosensor exhibited high sensitivity and selectivity, rapid response, good cell-membrane permeability and low cytotoxicity. All these features are favorable for in situ visualization of Cyt c for apoptosis research. Notably, the developed nanosensor was successfully applied to monitor intracellular release of Cyt c, and to visualize Cyt c in living zebrafish for the first time. Moreover, it also pro...
ChemSusChem, Sep 13, 2017
The serious environmental problems of modern society creates a great demand for the efficient upt... more The serious environmental problems of modern society creates a great demand for the efficient uptake of NH₃ by solvents. However, many shortcomings exist with the traditional aqueous absorbents, and efforts to use ionic liquids met limited success. In this work, we for the first time report that the design of hybrid deep eutectic solvents (DESs) with flexible hydrogen-bonded supramolecular network enabled both exceptional NH₃ uptake capacity and superior desorption-regeneration performance, along with superb NH₃/CO₂ selectivity and environmental merits. Elucidated by the molecular dynamic simulations and spectrum analysis, the abundant hydrogen-bonding sites in the hybrid DESs grasp the every atom of NH₃ molecule and enable a strong physical reversible solvation, while the multiple interactions among the hybrid components create a flexible hydrogen-bonded supramolecular network and allow for solvent-unbreaking absorption to ensure the full participation of solvent and process stabil...
Advanced healthcare materials, Jan 31, 2017
Graphene oxides (GO) are attracting much attention in the diagnosis and therapy of the subcutaneo... more Graphene oxides (GO) are attracting much attention in the diagnosis and therapy of the subcutaneous tumor as a novel biomaterial, but its diagnosis to tissue dysfunction is yet to be found. Here, a novel application of GO for diagnosis of renal dysfunction via contrast-enhanced computed tomography (CT) is proposed. In order to serve as contrast-enhanced agent, Ag nanoparticles (AgNPs) are composited on the surface of GO to promote its X-ray absorption, and then simvastatin is coinjected for eliminating in vivo toxicity induced by AgNPs. It is found that GO/AgNPs can enhance the imaging of CT into the lung, liver, and kidney of mice for a long circulation time (≈24 h) and a safety profile in vivo in the presence of simvastatin. Interestingly, the lower dose of GO/AgNPs (≈0.5 mg per kg bw) shows an excellent performance for CT imaging of renal perfusion, and visually exhibits the right renal dysfunction in model mice. Hence, this work suggests that graphene nanoparticles will play a v...
Green Chemistry, 2016
Both basic and non-basic nitrogen compounds can be efficiently removed from fuels by deep eutecti... more Both basic and non-basic nitrogen compounds can be efficiently removed from fuels by deep eutectic solvents.