Christelle Durance - Academia.edu (original) (raw)

Uploads

Papers by Christelle Durance

Research paper thumbnail of Socioeconomic and psychological factors associated with nonadherence to treatment in inflammatory bowel disease patients

Inflammatory Bowel Diseases, 2011

Adherence to treatment is a key condition in preventing relapses in inflammatory bowel disease (I... more Adherence to treatment is a key condition in preventing relapses in inflammatory bowel disease (IBD). The aims of this study were specifically to study socioeconomic and psychological factors and adherence to treatment in a large cohort of patients. A questionnaire concerning demographic, clinical, and psychosocial characteristics was mailed to 6000 IBD patients belonging to the French association of IBD patients (AFA). The questionnaire was also available on the Website of the AFA for nonmember patients to answer. Good adherence to treatment was defined as taking ≥ 80% of prescribed medication. Socioeconomic deprivation was assessed using the specific EPICES score (http://www.cetaf.asso.fr) developed in France. Anxiety and depression were assessed using the Hospital Anxiety and Depression scale. A total of 1069 women and 594 men (43.6 ± 15.4 years) completed the questionnaire; 1450 (87.2%) of them belonged to the AFA. In all, 1044 had Crohn's disease, 36 indeterminate colitis, and 583 ulcerative colitis. Adherence ≥ 80% was reported by 89.6% of patients. Factors associated with good adherence were: older age (P < 0.01), treatment with anti-tumor necrosis factor (TNF) (P < 0.0001), membership in the AFA (P = 0.006). Nonadherence increases with smoking (P = 0.02), constraints related to treatment (P < 10(-9) ), anxiety (P < 10(-6) ), and moodiness (P < 10(-5) ). There were no differences in adherence for the following: gender, type of IBD, activity and severity of the disease, socioeconomic deprivation, marital status, education level, and depression. In this large cohort of IBD patients, psychological distress and constraints related to treatment decrease adherence to treatment, while membership in a patients' association improves it.

Research paper thumbnail of S1215 Socio-Economic and Psychological Factors Associated With Adherence to Treatment in IBD Patients: Results of the Isseo Survey

Gastroenterology, 2010

« PreviousNext »Gastroenterology Volume 138, Issue 5, Supplement 1 , Pages S-206, May 2010. S1215... more « PreviousNext »Gastroenterology Volume 138, Issue 5, Supplement 1 , Pages S-206, May 2010. S1215 Socio-Economic and Psychological Factors Associated With Adherence to Treatment in IBD Patients: Results of the Isseo Survey. ...

Research paper thumbnail of Risk factors of anxiety and depression in inflammatory bowel disease

Inflammatory Bowel Diseases, 2012

Background: Little is known in inflammatory bowel disease (IBD) regarding risk factors for psycho... more Background: Little is known in inflammatory bowel disease (IBD) regarding risk factors for psychological distress. The aim of this work was to study the disease characteristics and socioeconomic factors associated with anxiety and depression in IBD. patients with IBD (1450 were members of the Association Francois Aupetit, French association of IBD patients) answered a questionnaire about psychological and socioeconomic factors and adherence to treatment. In this study we focused the analysis on the characteristics of IBD (type, location, severity, treatment) and socioeconomic factors (professional, educational, and marital status and Evaluation of Precarity and Inequalities in Health Examination Centers [EPICES] score of socioeconomic deprivation; score established in medical centers in France; http://www.cetaf.asso.fr) associated with depression and anxiety. Anxiety and depression were assessed by the Hospital Anxiety and Depression Scale. Comparison between groups according to the existence of depression or anxiety was carried out using univariate and multivariate analysis.

Research paper thumbnail of Socioeconomic and psychological factors associated with nonadherence to treatment in inflammatory bowel disease patients

Inflammatory Bowel Diseases, 2011

Adherence to treatment is a key condition in preventing relapses in inflammatory bowel disease (I... more Adherence to treatment is a key condition in preventing relapses in inflammatory bowel disease (IBD). The aims of this study were specifically to study socioeconomic and psychological factors and adherence to treatment in a large cohort of patients. A questionnaire concerning demographic, clinical, and psychosocial characteristics was mailed to 6000 IBD patients belonging to the French association of IBD patients (AFA). The questionnaire was also available on the Website of the AFA for nonmember patients to answer. Good adherence to treatment was defined as taking ≥ 80% of prescribed medication. Socioeconomic deprivation was assessed using the specific EPICES score (http://www.cetaf.asso.fr) developed in France. Anxiety and depression were assessed using the Hospital Anxiety and Depression scale. A total of 1069 women and 594 men (43.6 ± 15.4 years) completed the questionnaire; 1450 (87.2%) of them belonged to the AFA. In all, 1044 had Crohn's disease, 36 indeterminate colitis, and 583 ulcerative colitis. Adherence ≥ 80% was reported by 89.6% of patients. Factors associated with good adherence were: older age (P < 0.01), treatment with anti-tumor necrosis factor (TNF) (P < 0.0001), membership in the AFA (P = 0.006). Nonadherence increases with smoking (P = 0.02), constraints related to treatment (P < 10(-9) ), anxiety (P < 10(-6) ), and moodiness (P < 10(-5) ). There were no differences in adherence for the following: gender, type of IBD, activity and severity of the disease, socioeconomic deprivation, marital status, education level, and depression. In this large cohort of IBD patients, psychological distress and constraints related to treatment decrease adherence to treatment, while membership in a patients' association improves it.

Research paper thumbnail of S1215 Socio-Economic and Psychological Factors Associated With Adherence to Treatment in IBD Patients: Results of the Isseo Survey

Gastroenterology, 2010

« PreviousNext »Gastroenterology Volume 138, Issue 5, Supplement 1 , Pages S-206, May 2010. S1215... more « PreviousNext »Gastroenterology Volume 138, Issue 5, Supplement 1 , Pages S-206, May 2010. S1215 Socio-Economic and Psychological Factors Associated With Adherence to Treatment in IBD Patients: Results of the Isseo Survey. ...

Research paper thumbnail of Risk factors of anxiety and depression in inflammatory bowel disease

Inflammatory Bowel Diseases, 2012

Background: Little is known in inflammatory bowel disease (IBD) regarding risk factors for psycho... more Background: Little is known in inflammatory bowel disease (IBD) regarding risk factors for psychological distress. The aim of this work was to study the disease characteristics and socioeconomic factors associated with anxiety and depression in IBD. patients with IBD (1450 were members of the Association Francois Aupetit, French association of IBD patients) answered a questionnaire about psychological and socioeconomic factors and adherence to treatment. In this study we focused the analysis on the characteristics of IBD (type, location, severity, treatment) and socioeconomic factors (professional, educational, and marital status and Evaluation of Precarity and Inequalities in Health Examination Centers [EPICES] score of socioeconomic deprivation; score established in medical centers in France; http://www.cetaf.asso.fr) associated with depression and anxiety. Anxiety and depression were assessed by the Hospital Anxiety and Depression Scale. Comparison between groups according to the existence of depression or anxiety was carried out using univariate and multivariate analysis.