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Papers by Christiano Caldeira

Research paper thumbnail of Internal Mammary Hypoperfusion Syndrome

Japanese Circulation Journal-english Edition, 1997

Research paper thumbnail of Ablation of Left Ventricular Tachycardia via Transeptal Approach and Crossing of a Mechanical Mitral Valve Prosthesis: CROSSING A MECHANICAL MITRAL VALVE

Pace-pacing and Clinical Electrophysiology, 2010

This report describes the clinical course of a patient with left ventricular assist device (LVAD)... more This report describes the clinical course of a patient with left ventricular assist device (LVAD) and refractory ventricular tachycardia (VT) who underwent successful left ventricular (LV) mapping and ablation complicated by the presence of a bioprosthetic aortic and a mechanical mitral valve. LV catheterization was achieved by crossing the mechanical valve. The patient remained hemodynamically stable during the procedure most likely as a result of LVAD support. There were no complications. A recurrence of monomorphic VT 2 months later required a second VT ablation procedure using the same transseptal-transmitral approach. The patient has since been free of implantable cardioverter defibrillator shocks for 2 months since the second procedure. (PACE 2010; 900–903)

Research paper thumbnail of The Double Jeopardy of Blunt Chest Trauma: A Case Report and Review

Echocardiography-a Journal of Cardiovascular Ultrasound and Allied Techniques, 2006

Cardiac injury, specifically valvular rupture, must be considered after blunt chest trauma even i... more Cardiac injury, specifically valvular rupture, must be considered after blunt chest trauma even in previously healthy patients. Isolated mitral regurgitation (MR) and tricuspid regurgitation (TR) due to blunt chest trauma are rare phenomena. More unique is simultaneous complete papillary muscle rupture of the mitral valve (MV) and tricuspid valve (TV) with only four patients being previously reported in the literature. This case describes a patient with complete transection of the posteromedial papillary muscle of the MV with severe MR and a concomitant flail TV with severe TR following a motor vehicular accident. The importance of transthoracic and transesophageal echocardiography in the early evaluation of patients following blunt chest trauma is also highlighted by this case.

Research paper thumbnail of Acute Suprarenal Aortogastric Fistulae Caused by Gunshot Wounds

The Journal of Trauma: Injury, Infection, and Critical Care, 1996

Penetrating suprarenal aortic injuries carry high mortality rates. Difficulties in surgical expos... more Penetrating suprarenal aortic injuries carry high mortality rates. Difficulties in surgical exposure and bleeding control in this area add to the ominous prognosis. In rare occasions, synchronous injury to the adjacent upper part of stomach may lead to an acute aortogastric fistula, resulting in aortic bleeding into the stomach instead of the peritoneal cavity. Filling of the stomach with blood may temporarily tamponade the aortic perforation. Distortion of this delicate communication during dissection before proximal and distal vascular control is achieved could result in catastrophic hemorrhage. Therefore, recognition of the importance of a fully distended stomach at the suspicion of aortic injury is essential in directing a particular surgical strategy that aims to achieve an unrestricted operative exposure and successful bleeding control.

Research paper thumbnail of Experimental murine paracoccidioidomycosis: relationship among the dissemination of the infection, humoral and cellular immune responses

Clinical and Experimental Immunology, 2008

The dissemination of Paracoccidioides brasiliensis cells to the heart, omentum/pancreas, spleen, ... more The dissemination of Paracoccidioides brasiliensis cells to the heart, omentum/pancreas, spleen, liver and lungs, assessed by colony forming unit (CFU) counts, the levels of specific antibodies to this fungal agent (by ELISA), and the specific DTH reaction were studied in susceptible (B10.A) and resistant (A/Sn) mice. The animals were infected intraperitoneally with P. brasiliensis yeast cells and were evaluated 2, 4, 12 and 16 weeks later. The mosl remarkable differences between the two mouse strains were observed 16 weeks after infection, when B10.A mice displayed high numbers ofCFU in all examined organs, except the heart, high antibody titres, and depressed DTH response. At this point. A/Sn mice presented low or absent CFU in all organs, low antibody litres and expressive DTH response. The CFU counts were shown to be a reliable parameter to discriminate susceptible from resistant animals. The fungal load in the most affected organs correlated wilh the antibody litres and was inversely correlated with the intensity of the DTH reaction. The patterns of immune response in this model mimic human paracoccidioidomycosis, in which high specific antibody levels and depressed DTH reactions are found in multifocal and severe forms of the disease.

Research paper thumbnail of A simple method of left ventricular reconstruction without patch for ischemic cardiomyopathy

Annals of Thoracic Surgery, 2001

Interest in reconstructive surgery for ischemic cardiomyopathy has increased. We prospectively st... more Interest in reconstructive surgery for ischemic cardiomyopathy has increased. We prospectively studied patients undergoing left ventricular reconstruction for ischemic cardiomyopathy. This report describes our technique for no-patch repair of left anterior descending aneurysms or akinetic areas. Patients are selected for surgery with discreet left anterior descending scar, usually detected by preoperative magnetic resonance imaging scan and three-dimensional echocardiography, with compensated heart failure or other indications for surgery such as severe coronary artery disease or mitral regurgitation.

Research paper thumbnail of Elevated B-Type Natriuretic Peptide Without Volume Overload in a Left Ventricular Assist Device Patient With a Subdural Hematoma

Asaio Journal, 2010

We report a case of elevated B-type natriuretic peptide (BNP) without volume overload in a left v... more We report a case of elevated B-type natriuretic peptide (BNP) without volume overload in a left ventricular assist device patient with a subdural hematoma and cerebral salt wasting syndrome suggesting a noncardiac etiology for BNP elevation.

Research paper thumbnail of Internal Mammary Hypoperfusion Syndrome

Japanese Circulation Journal-english Edition, 1997

Research paper thumbnail of Ablation of Left Ventricular Tachycardia via Transeptal Approach and Crossing of a Mechanical Mitral Valve Prosthesis: CROSSING A MECHANICAL MITRAL VALVE

Pace-pacing and Clinical Electrophysiology, 2010

This report describes the clinical course of a patient with left ventricular assist device (LVAD)... more This report describes the clinical course of a patient with left ventricular assist device (LVAD) and refractory ventricular tachycardia (VT) who underwent successful left ventricular (LV) mapping and ablation complicated by the presence of a bioprosthetic aortic and a mechanical mitral valve. LV catheterization was achieved by crossing the mechanical valve. The patient remained hemodynamically stable during the procedure most likely as a result of LVAD support. There were no complications. A recurrence of monomorphic VT 2 months later required a second VT ablation procedure using the same transseptal-transmitral approach. The patient has since been free of implantable cardioverter defibrillator shocks for 2 months since the second procedure. (PACE 2010; 900–903)

Research paper thumbnail of The Double Jeopardy of Blunt Chest Trauma: A Case Report and Review

Echocardiography-a Journal of Cardiovascular Ultrasound and Allied Techniques, 2006

Cardiac injury, specifically valvular rupture, must be considered after blunt chest trauma even i... more Cardiac injury, specifically valvular rupture, must be considered after blunt chest trauma even in previously healthy patients. Isolated mitral regurgitation (MR) and tricuspid regurgitation (TR) due to blunt chest trauma are rare phenomena. More unique is simultaneous complete papillary muscle rupture of the mitral valve (MV) and tricuspid valve (TV) with only four patients being previously reported in the literature. This case describes a patient with complete transection of the posteromedial papillary muscle of the MV with severe MR and a concomitant flail TV with severe TR following a motor vehicular accident. The importance of transthoracic and transesophageal echocardiography in the early evaluation of patients following blunt chest trauma is also highlighted by this case.

Research paper thumbnail of Acute Suprarenal Aortogastric Fistulae Caused by Gunshot Wounds

The Journal of Trauma: Injury, Infection, and Critical Care, 1996

Penetrating suprarenal aortic injuries carry high mortality rates. Difficulties in surgical expos... more Penetrating suprarenal aortic injuries carry high mortality rates. Difficulties in surgical exposure and bleeding control in this area add to the ominous prognosis. In rare occasions, synchronous injury to the adjacent upper part of stomach may lead to an acute aortogastric fistula, resulting in aortic bleeding into the stomach instead of the peritoneal cavity. Filling of the stomach with blood may temporarily tamponade the aortic perforation. Distortion of this delicate communication during dissection before proximal and distal vascular control is achieved could result in catastrophic hemorrhage. Therefore, recognition of the importance of a fully distended stomach at the suspicion of aortic injury is essential in directing a particular surgical strategy that aims to achieve an unrestricted operative exposure and successful bleeding control.

Research paper thumbnail of Experimental murine paracoccidioidomycosis: relationship among the dissemination of the infection, humoral and cellular immune responses

Clinical and Experimental Immunology, 2008

The dissemination of Paracoccidioides brasiliensis cells to the heart, omentum/pancreas, spleen, ... more The dissemination of Paracoccidioides brasiliensis cells to the heart, omentum/pancreas, spleen, liver and lungs, assessed by colony forming unit (CFU) counts, the levels of specific antibodies to this fungal agent (by ELISA), and the specific DTH reaction were studied in susceptible (B10.A) and resistant (A/Sn) mice. The animals were infected intraperitoneally with P. brasiliensis yeast cells and were evaluated 2, 4, 12 and 16 weeks later. The mosl remarkable differences between the two mouse strains were observed 16 weeks after infection, when B10.A mice displayed high numbers ofCFU in all examined organs, except the heart, high antibody titres, and depressed DTH response. At this point. A/Sn mice presented low or absent CFU in all organs, low antibody litres and expressive DTH response. The CFU counts were shown to be a reliable parameter to discriminate susceptible from resistant animals. The fungal load in the most affected organs correlated wilh the antibody litres and was inversely correlated with the intensity of the DTH reaction. The patterns of immune response in this model mimic human paracoccidioidomycosis, in which high specific antibody levels and depressed DTH reactions are found in multifocal and severe forms of the disease.

Research paper thumbnail of A simple method of left ventricular reconstruction without patch for ischemic cardiomyopathy

Annals of Thoracic Surgery, 2001

Interest in reconstructive surgery for ischemic cardiomyopathy has increased. We prospectively st... more Interest in reconstructive surgery for ischemic cardiomyopathy has increased. We prospectively studied patients undergoing left ventricular reconstruction for ischemic cardiomyopathy. This report describes our technique for no-patch repair of left anterior descending aneurysms or akinetic areas. Patients are selected for surgery with discreet left anterior descending scar, usually detected by preoperative magnetic resonance imaging scan and three-dimensional echocardiography, with compensated heart failure or other indications for surgery such as severe coronary artery disease or mitral regurgitation.

Research paper thumbnail of Elevated B-Type Natriuretic Peptide Without Volume Overload in a Left Ventricular Assist Device Patient With a Subdural Hematoma

Asaio Journal, 2010

We report a case of elevated B-type natriuretic peptide (BNP) without volume overload in a left v... more We report a case of elevated B-type natriuretic peptide (BNP) without volume overload in a left ventricular assist device patient with a subdural hematoma and cerebral salt wasting syndrome suggesting a noncardiac etiology for BNP elevation.