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Journal of Human Growth and Development, 2009
Resumo MESQUITA, Maria dos Anjos e SEGRE, Conceição Aparecida de Mattos. Freqüência dos efeitos d... more Resumo MESQUITA, Maria dos Anjos e SEGRE, Conceição Aparecida de Mattos. Freqüência dos efeitos do álcool no feto e padrão de consumo de bebidas alcoólicas pelas gestantes de maternidade pública da cidade de São Paulo. Rev. bras. crescimento ...
Einstein, 2006
Objective: To evaluate auditory brainstem responses in term newborns with hyperbilirubinemia. Met... more Objective: To evaluate auditory brainstem responses in term newborns with hyperbilirubinemia. Methods: Seventy-one newborns, 35 with aggravated physiological neonatal jaundice (group I), 24 with ABO blood incompatibility (group II) and 12 not suffering from jaundice or any other disease were submitted to auditory brainstem responses. Statistical analysis of variance was performed to evaluate waveform reproducibility, absolute and interwave latencies, and Pearson coefficient was used to evaluate the association between the level of serum bilirubin and abnormalities in the auditory brainstem responses. Results: According to the criteria assumed in the present paper waveform alterations were more frequently found in group II than in the control group (p = 0.023). No significant differences were observed between groups I and II (p = 0.083) or between control group and group I (p = 0.166). Wave I latency at 80 dBHL for good reproducibility responses and III-V interwave latency at 40 dBHL for poor reproducibility responses of newborns with hyperbilirubinemia showed significant findings in relation to the control group (0.008 and 0.004 respectively). There was positive, weak (9%) association between serum indirect bilirubin levels and auditory brainstem responses only when the two groups were analyzed together. Conclusions: Neonatal hyperbilirubinemia changed the conduction of auditory stimulus in term newborns with jaundice caused by ABO blood incompatibility. There was poor positive association between plasma levels of bilirubin and abnormalities in auditory brainstem responses.
Psl Quarterly Review, Mar 27, 2014
Rev Paul Pediatr, Mar 1, 1986
The user has requested enhancement of the downloaded file. All in-text references underlined in b... more The user has requested enhancement of the downloaded file. All in-text references underlined in blue are added to the original document and are linked to publications on ResearchGate, letting you access and read them immediately. einstein. 2007; 5(3):231-238 231
J Pediatr, 2001
OBJECTIVE: Growth curves can be used to assess intrauterine growth, to predict diseases in newbor... more OBJECTIVE: Growth curves can be used to assess intrauterine growth, to predict diseases in newborns, and to characterize different populations. The objective of this study was to obtain intrauterine growth curves of newborns from the maternity ward of the Hospital Albert Einstein (MAE) and compare them with intrauterine growth curves of a population from California, USA. METHODS: We plotted the growth curves according to weight at birth and gestational age, which was obtained according to information from the mother, after the 32nd week of gestation, between February 1995 and February 1999. We calculated the birth weights for the 10th, 50th, and 90th percentiles by each gestational age and compared them with those presented by California growth curves. RESULTS: The growth curves for the 10th and the 50th percentiles did not differ from the California growth curves. For the 90th percentile, however, the MAE growth curves were lower than those of California. The MAE population presented fewer small-for-gestational age (SGA) and big-for-gestational age (BGA) newborns when assessed according to the California curves. The categories of SGA, normal, and BGA for both male and female newborns indicated a statistically significant relation with the weight gain of mothers. CONCLUSIONS: The two populations assessed in this study were different according to intrauterine growth curves. Further studies should be carried out in order to identify specific factors that may be acting on the MAE population.
Rev Paul Pediatr, Mar 1, 1986
Revista Brasileira De Crescimento E Desenvolvimento Humano, Aug 1, 2010
Objective: To determine serum levels of insulin-like growth factor-I, free insulin-like growth fa... more Objective: To determine serum levels of insulin-like growth factor-I, free insulin-like growth factor-I and its binding proteins in maternal serum and in cord blood of two groups of newborns with different birth weights. Methods: A group of 60 healthy pregnant women and their respective neonates with birth weight ≥ 2500g (group 1) and another comprising 23 healthy pregnant women and their respective neonates with birth weight ≤ 2500g (group 2) were studied. Maternal and neonatal blood samples were analyzed for levels of insulin-like growth factor-I, free insulin-like growth factor-I, binding protein-1 and binding protein-3 by radioimmunoassay. Statistical analysis: Student's t test and multiple regression analysis. Values of p < 0.05 were considered statistically significant. Results: The t test showed that maternal insulin-like growth factor-I, neonatal insulin-like growth factor-I, and neonatal binding protein-3 values were significantly higher in Group 1 than in Group 2. In both groups maternal values were higher than those of their neonates (p < 0.05). Multiple regression analysis showed a positive correlation between neonatal anthropometric variables and neonatal insulin-like growth factor-I. Maternal binding protein-1 showed a negative correlation with neonatal insulin-like growth factor-I and binding protein-3. There was a positive correlation between maternal insulin-like growth factor-I and neonatal ratio free insulin-like growth factor-I/total insulin-like growth factor-I. Conclusion: The findings of this study suggest that insulin-like growth factor-I and its binding proteins 1 and 3 play a role in the regulation of late fetal growth in normal Brazilian pregnant women.
Rev Paul Pediatr, Jun 1, 1984
Journal of Human Growth and Development, 2010
Rev Paul Pediatr, Mar 1, 2000
Journal of Human Growth and Development, 2009
Resumo MESQUITA, Maria dos Anjos e SEGRE, Conceição Aparecida de Mattos. Freqüência dos efeitos d... more Resumo MESQUITA, Maria dos Anjos e SEGRE, Conceição Aparecida de Mattos. Freqüência dos efeitos do álcool no feto e padrão de consumo de bebidas alcoólicas pelas gestantes de maternidade pública da cidade de São Paulo. Rev. bras. crescimento ...
Einstein, 2006
Objective: To evaluate auditory brainstem responses in term newborns with hyperbilirubinemia. Met... more Objective: To evaluate auditory brainstem responses in term newborns with hyperbilirubinemia. Methods: Seventy-one newborns, 35 with aggravated physiological neonatal jaundice (group I), 24 with ABO blood incompatibility (group II) and 12 not suffering from jaundice or any other disease were submitted to auditory brainstem responses. Statistical analysis of variance was performed to evaluate waveform reproducibility, absolute and interwave latencies, and Pearson coefficient was used to evaluate the association between the level of serum bilirubin and abnormalities in the auditory brainstem responses. Results: According to the criteria assumed in the present paper waveform alterations were more frequently found in group II than in the control group (p = 0.023). No significant differences were observed between groups I and II (p = 0.083) or between control group and group I (p = 0.166). Wave I latency at 80 dBHL for good reproducibility responses and III-V interwave latency at 40 dBHL for poor reproducibility responses of newborns with hyperbilirubinemia showed significant findings in relation to the control group (0.008 and 0.004 respectively). There was positive, weak (9%) association between serum indirect bilirubin levels and auditory brainstem responses only when the two groups were analyzed together. Conclusions: Neonatal hyperbilirubinemia changed the conduction of auditory stimulus in term newborns with jaundice caused by ABO blood incompatibility. There was poor positive association between plasma levels of bilirubin and abnormalities in auditory brainstem responses.
Psl Quarterly Review, Mar 27, 2014
Rev Paul Pediatr, Mar 1, 1986
The user has requested enhancement of the downloaded file. All in-text references underlined in b... more The user has requested enhancement of the downloaded file. All in-text references underlined in blue are added to the original document and are linked to publications on ResearchGate, letting you access and read them immediately. einstein. 2007; 5(3):231-238 231
J Pediatr, 2001
OBJECTIVE: Growth curves can be used to assess intrauterine growth, to predict diseases in newbor... more OBJECTIVE: Growth curves can be used to assess intrauterine growth, to predict diseases in newborns, and to characterize different populations. The objective of this study was to obtain intrauterine growth curves of newborns from the maternity ward of the Hospital Albert Einstein (MAE) and compare them with intrauterine growth curves of a population from California, USA. METHODS: We plotted the growth curves according to weight at birth and gestational age, which was obtained according to information from the mother, after the 32nd week of gestation, between February 1995 and February 1999. We calculated the birth weights for the 10th, 50th, and 90th percentiles by each gestational age and compared them with those presented by California growth curves. RESULTS: The growth curves for the 10th and the 50th percentiles did not differ from the California growth curves. For the 90th percentile, however, the MAE growth curves were lower than those of California. The MAE population presented fewer small-for-gestational age (SGA) and big-for-gestational age (BGA) newborns when assessed according to the California curves. The categories of SGA, normal, and BGA for both male and female newborns indicated a statistically significant relation with the weight gain of mothers. CONCLUSIONS: The two populations assessed in this study were different according to intrauterine growth curves. Further studies should be carried out in order to identify specific factors that may be acting on the MAE population.
Rev Paul Pediatr, Mar 1, 1986
Revista Brasileira De Crescimento E Desenvolvimento Humano, Aug 1, 2010
Objective: To determine serum levels of insulin-like growth factor-I, free insulin-like growth fa... more Objective: To determine serum levels of insulin-like growth factor-I, free insulin-like growth factor-I and its binding proteins in maternal serum and in cord blood of two groups of newborns with different birth weights. Methods: A group of 60 healthy pregnant women and their respective neonates with birth weight ≥ 2500g (group 1) and another comprising 23 healthy pregnant women and their respective neonates with birth weight ≤ 2500g (group 2) were studied. Maternal and neonatal blood samples were analyzed for levels of insulin-like growth factor-I, free insulin-like growth factor-I, binding protein-1 and binding protein-3 by radioimmunoassay. Statistical analysis: Student's t test and multiple regression analysis. Values of p < 0.05 were considered statistically significant. Results: The t test showed that maternal insulin-like growth factor-I, neonatal insulin-like growth factor-I, and neonatal binding protein-3 values were significantly higher in Group 1 than in Group 2. In both groups maternal values were higher than those of their neonates (p < 0.05). Multiple regression analysis showed a positive correlation between neonatal anthropometric variables and neonatal insulin-like growth factor-I. Maternal binding protein-1 showed a negative correlation with neonatal insulin-like growth factor-I and binding protein-3. There was a positive correlation between maternal insulin-like growth factor-I and neonatal ratio free insulin-like growth factor-I/total insulin-like growth factor-I. Conclusion: The findings of this study suggest that insulin-like growth factor-I and its binding proteins 1 and 3 play a role in the regulation of late fetal growth in normal Brazilian pregnant women.
Rev Paul Pediatr, Jun 1, 1984
Journal of Human Growth and Development, 2010
Rev Paul Pediatr, Mar 1, 2000