Conrad Timon - Academia.edu (original) (raw)

Papers by Conrad Timon

Research paper thumbnail of Randomized Trial Tissue Adhesive/Staples in Thyroidectomy

Otolaryngology-Head and Neck Surgery, Aug 1, 2008

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Research paper thumbnail of Cervical meningocoele presenting as a neck mass in a patient with neurofibromatosis 1

Journal of Laryngology and Otology, May 1, 1992

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Research paper thumbnail of EP-1088: Defining radiation induced malignancies in the HPV era

Radiotherapy and Oncology, 2014

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Research paper thumbnail of Hypopharyngeal involvement by thyroid cancer

The Journal of Laryngology & Otology, 1989

Direct upper airway infiltration by thyroid neoplasia is a rare occurrence, a unique case of papi... more Direct upper airway infiltration by thyroid neoplasia is a rare occurrence, a unique case of papillary thyroid neoplasia presenting as a pyriform fossa mass is described and the management of these problem patients is discussed, emphasising the controversy between radical and conservative surgery.The possibility that the thyroid tumour resulted from previous radioactive iodine prescribed for thyrotoxicosis is also considered.

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Research paper thumbnail of Endoscopic sinus surgery outcome in patients with symptomatic chronic rhinosinusitis and minimal changes on computerised tomography

Irish Medical Journal, 2006

This study evaluated the benefit of Functional Endoscopic Sinus Surgery (FESS) in relieving sympt... more This study evaluated the benefit of Functional Endoscopic Sinus Surgery (FESS) in relieving symptoms of chronic rhinosinusitis in patients with minimal preoperative disease involvement as evident on C.T scan and assesses the accuracy of C.T in predicting the outcome of FESS using the Lund-Mackay staging system. 78 patients were stratified according to the extent of their pre-operative C.T disease involvement. Pre and Post operative symptom status were evaluated using Visual Analogue Score (V.A.S) Questionnaire. Using a chi-square test, no statistically significant difference in outcome following FESS was found between those with minimal changes and those patients with more extensive involvement on C.T. Patients benefited from surgery irrespective of pre-operative C.T score. We conclude from this study that FESS appears to have a beneficial role in relieving symptoms of chronic rhinosinusitis in patients with minimal as well as more extensive preoperative C.T disease involvement.

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Research paper thumbnail of Pre‐operative testing for <scp>SARS‐CoV</scp> ‐2 and outcomes in otolaryngology surgery during the pandemic: A <scp>multi‐center</scp> experience

Laryngoscope investigative otolaryngology, Jul 5, 2021

IntroductionPreoperative testing for COVID‐19 has become widely established to avoid inadvertent ... more IntroductionPreoperative testing for COVID‐19 has become widely established to avoid inadvertent surgery on patients with COVID‐19 and prevent hospital outbreaks.MethodsA prospective cross sectional study was carried out in two university hospitals examining the pre‐operative protocols for patients undergoing otolaryngology surgery and the incidence of COVID‐19 within 30 days of surgery in patients and the otolaryngologists performing surgery.ResultsOne hundred and seventy‐three patients were recruited. One hundred and twenty‐three (71%) patients “cocooned” for 14 days prior to surgery. All completed a questionnaire prior to admission. One hundred and fifty‐six patients (90%) had reverse transcriptase‐polymerase chain reaction (RT‐PCR) nasopharyngeal swabs, 14 patients (8%) had CT thorax. No cases of COVID‐19 were detected among patients followed up at 30 days. Two surgeons developed COVID‐19 early during the study period.ConclusionCurrent pre‐operative testing protocols consisting primarily of questionnaires and RT‐PCR resulted in zero cases of COVID in this cohort. It is possible that COVID‐19 restrictions and high proportion of patients cocooning preoperatively were factors in ensuring a low rate of COVID‐19 post‐operatively.

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Research paper thumbnail of Occult pharyngeal perforation secondary to ‘pencil injury’

Journal of Laryngology and Otology, Sep 1, 1996

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Research paper thumbnail of A histological comparison of deep and superficial lobe pleomorphic adenomas of the parotid gland

Head & neck, Jul 21, 2003

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Research paper thumbnail of The Node-Negative Neck: Accuracy of Clinical Intraoperative Lymph Node Assessment for Metastatic Disease in Head and Neck Cancer

Laryngoscope, Apr 1, 2002

Objectives/Hypothesis Often, the type of neck dissection performed in patients with head and neck... more Objectives/Hypothesis Often, the type of neck dissection performed in patients with head and neck malignancy is finally determined by intraoperative assessment of clinically suspect lymph nodes by frozen section. This prospective study aimed to assess the accuracy of clinical intraoperative lymph node assessment and therefore to examine validity of the underlying assumption that the surgeon can consistently identify nodes that contain metastatic tumor. We also aimed to assess whether gross morphological characteristics of the lymph nodes examined could be correlated with nodal status and therefore used to predict those nodes containing metastatic disease.Study Design A prospective study assessing the accuracy of clinical intraoperative lymph node assessment in the node‐negative neck.Methods Forty‐six neck dissections from 34 patients with head and neck cancer were prospectively examined intraoperatively by a single surgeon. All obvious nodes were clinically assessed, morphologically described, and subsequently correlated with pathological findings.Results Sixty palpable nodes were identified in 32 neck dissections. They were clinically categorized as malignant or suspect (22) or benign (38). Pathological examination revealed a false‐positive rate of 30% and a false‐negative rate of 44%. The sensitivity of intraoperative lymph node assessment was 56%, and the specificity was 70%. Apart from “infiltration,” morphological characteristics could not be correlated with nodal status. In the 14 neck dissections with no obviously palpable lymph nodes, 4 (29%) were positive for metastatic disease.Conclusions In the node‐negative neck, intraoperative assessment does not seem to improve the accuracy of staging. The only parameter of benefit and correlating with metastatic disease is clinical evidence of infiltration. The assumption that frozen section is a good determinate for selection of type of neck dissection is questionable. If selective neck dissection is not found to be therapeutic, its use leads to over‐reliance on other therapeutic treatment such as postoperative radiotherapy, depriving the patient of a potential useful treatment modality in cases of locoregional recurrence.

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Research paper thumbnail of Laryngeal tuberculosis: an important diagnosis

Journal of Laryngology and Otology, Nov 1, 2000

The incidence of laryngeal tuberculosis is increasing worldwide. To ensure early diagnosis it is ... more The incidence of laryngeal tuberculosis is increasing worldwide. To ensure early diagnosis it is important for physicians and otolaryngologists to recognize its cardinal signs and symptoms. We present two recent cases of laryngeal tuberculosis that presented to our department. We outline potential pitfalls in diagnosis, and highlight the importance of obtaining a tissue diagnosis. The literature is reviewed, and the treatment options outlined.

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Research paper thumbnail of Incidence of sinusitis after orbital decompression

Otolaryngology-Head and Neck Surgery, Aug 1, 1997

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Research paper thumbnail of Endolaryngeal cysts presenting with acute respiratory distress*

Clinical otolaryngology and allied sciences, Oct 1, 2004

This is a retrospective review of benign cysts of the adult endolarynx that presented as airway e... more This is a retrospective review of benign cysts of the adult endolarynx that presented as airway emergencies in four teaching hospitals of Dublin, Ireland, over 2 years. During that period nine patients with endolaryngeal cysts necessitating emergency airway intervention were managed. All cases were treated by endoscopic microlaryngeal marsupialization after securing the airway either at the same time or as a staged procedure. Four of these patients required tracheostomies, one performed under local anaesthesia and the others after initial endotracheal intubation. Definitive treatment was carried out in six cases at initial endoscopic diagnosis. Three of the tracheostomized patients had a staged management, two because of their medical status and one for further investigations. On the basis of our findings we suggest that all benign cysts around the endolarynx should simply be called &#39;endolaryngeal cysts&#39; instead of the current practice of trying to classify them into various histological and morphological types with no prognostic or management differences. Benign cysts of the endolarynx presenting with airway obstruction would appear to be more frequent than is generally maintained in the literature.

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Research paper thumbnail of An unusual Case of External Ear Inflammation Caused by Sarcoidosis

Ear, nose, & throat journal, Dec 1, 2003

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Research paper thumbnail of Surgical management of lymphangiomas in adults

Journal of Laryngology and Otology, Jun 1, 1996

Lymphangiomas are uncommon benign congenital tumours. Most occur in the head and neck region and ... more Lymphangiomas are uncommon benign congenital tumours. Most occur in the head and neck region and the vast majority present before the age of two. This paper describes the presentation and management of four cases presenting after puberty and involving the parotid gland. The cases are unusual in that all were intimately associated with the facial nerve and in an older population. The value of selective neck dissection and facial nerve exposure as an approach to these lesions is discussed.

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Research paper thumbnail of Role of human papillomavirus in oropharyngeal squamous cell carcinoma: A review

World Journal of Clinical Cases, 2014

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Research paper thumbnail of The Westaby T-Y tracheobronchial stent in otolaryngology

Journal of Laryngology and Otology, Jul 1, 1999

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Research paper thumbnail of Facial node involvement in head and neck cancer

Head & neck, 2004

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Research paper thumbnail of Head and neck schwannomas – a 10 year review

Journal of Laryngology and Otology, Feb 1, 2000

Schwannomas of the head and neck are uncommon tumours that arise from any peripheral, cranial or ... more Schwannomas of the head and neck are uncommon tumours that arise from any peripheral, cranial or autonomic nerve. Twenty-five to 45 per cent of extracranial schwannomas occur in the head and neck region and thus are usually in the domain of the otolaryngologist. They usually present insidiously and thus are often diagnosed incorrectly or after lengthy delays, however, better imaging and cytological techniques have lessened this to some degree more recently. For benign lesions conservative surgical excision is the treatment of choice bearing in mind possible vagal or sympathetic chain injury. Malignant schwannomas are best treated with wide excision where possible. The role of adjuvant therapy remains uncertain and irrespective of treatment modality prognosis is poor with an overall survival of 15 per cent. However, recent advances in ras oncogene inhibitors may hold hope for the future.

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Research paper thumbnail of AB0642 Otolaryngeal Manifestations of Behçet's Disease in a Northern European Population

Annals of the Rheumatic Diseases, Jun 1, 2015

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Research paper thumbnail of Lingual granuloma of pregnancy

Revue de laryngologie - otologie - rhinologie, 2008

Pyogenic granuloma gravidarum is a rare condition. There have been very few reports in the litera... more Pyogenic granuloma gravidarum is a rare condition. There have been very few reports in the literature of these tumours affecting the tongue. We describe a case of pyogenic granuloma occurring on the tongue of a female who was 32 weeks pregnant. We present the clinical and histopathological features of this rare condition, discuss treatment options and review current literature.

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Research paper thumbnail of Randomized Trial Tissue Adhesive/Staples in Thyroidectomy

Otolaryngology-Head and Neck Surgery, Aug 1, 2008

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Research paper thumbnail of Cervical meningocoele presenting as a neck mass in a patient with neurofibromatosis 1

Journal of Laryngology and Otology, May 1, 1992

Bookmarks Related papers MentionsView impact

Research paper thumbnail of EP-1088: Defining radiation induced malignancies in the HPV era

Radiotherapy and Oncology, 2014

Bookmarks Related papers MentionsView impact

Research paper thumbnail of Hypopharyngeal involvement by thyroid cancer

The Journal of Laryngology & Otology, 1989

Direct upper airway infiltration by thyroid neoplasia is a rare occurrence, a unique case of papi... more Direct upper airway infiltration by thyroid neoplasia is a rare occurrence, a unique case of papillary thyroid neoplasia presenting as a pyriform fossa mass is described and the management of these problem patients is discussed, emphasising the controversy between radical and conservative surgery.The possibility that the thyroid tumour resulted from previous radioactive iodine prescribed for thyrotoxicosis is also considered.

Bookmarks Related papers MentionsView impact

Research paper thumbnail of Endoscopic sinus surgery outcome in patients with symptomatic chronic rhinosinusitis and minimal changes on computerised tomography

Irish Medical Journal, 2006

This study evaluated the benefit of Functional Endoscopic Sinus Surgery (FESS) in relieving sympt... more This study evaluated the benefit of Functional Endoscopic Sinus Surgery (FESS) in relieving symptoms of chronic rhinosinusitis in patients with minimal preoperative disease involvement as evident on C.T scan and assesses the accuracy of C.T in predicting the outcome of FESS using the Lund-Mackay staging system. 78 patients were stratified according to the extent of their pre-operative C.T disease involvement. Pre and Post operative symptom status were evaluated using Visual Analogue Score (V.A.S) Questionnaire. Using a chi-square test, no statistically significant difference in outcome following FESS was found between those with minimal changes and those patients with more extensive involvement on C.T. Patients benefited from surgery irrespective of pre-operative C.T score. We conclude from this study that FESS appears to have a beneficial role in relieving symptoms of chronic rhinosinusitis in patients with minimal as well as more extensive preoperative C.T disease involvement.

Bookmarks Related papers MentionsView impact

Research paper thumbnail of Pre‐operative testing for <scp>SARS‐CoV</scp> ‐2 and outcomes in otolaryngology surgery during the pandemic: A <scp>multi‐center</scp> experience

Laryngoscope investigative otolaryngology, Jul 5, 2021

IntroductionPreoperative testing for COVID‐19 has become widely established to avoid inadvertent ... more IntroductionPreoperative testing for COVID‐19 has become widely established to avoid inadvertent surgery on patients with COVID‐19 and prevent hospital outbreaks.MethodsA prospective cross sectional study was carried out in two university hospitals examining the pre‐operative protocols for patients undergoing otolaryngology surgery and the incidence of COVID‐19 within 30 days of surgery in patients and the otolaryngologists performing surgery.ResultsOne hundred and seventy‐three patients were recruited. One hundred and twenty‐three (71%) patients “cocooned” for 14 days prior to surgery. All completed a questionnaire prior to admission. One hundred and fifty‐six patients (90%) had reverse transcriptase‐polymerase chain reaction (RT‐PCR) nasopharyngeal swabs, 14 patients (8%) had CT thorax. No cases of COVID‐19 were detected among patients followed up at 30 days. Two surgeons developed COVID‐19 early during the study period.ConclusionCurrent pre‐operative testing protocols consisting primarily of questionnaires and RT‐PCR resulted in zero cases of COVID in this cohort. It is possible that COVID‐19 restrictions and high proportion of patients cocooning preoperatively were factors in ensuring a low rate of COVID‐19 post‐operatively.

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Research paper thumbnail of Occult pharyngeal perforation secondary to ‘pencil injury’

Journal of Laryngology and Otology, Sep 1, 1996

Bookmarks Related papers MentionsView impact

Research paper thumbnail of A histological comparison of deep and superficial lobe pleomorphic adenomas of the parotid gland

Head & neck, Jul 21, 2003

Bookmarks Related papers MentionsView impact

Research paper thumbnail of The Node-Negative Neck: Accuracy of Clinical Intraoperative Lymph Node Assessment for Metastatic Disease in Head and Neck Cancer

Laryngoscope, Apr 1, 2002

Objectives/Hypothesis Often, the type of neck dissection performed in patients with head and neck... more Objectives/Hypothesis Often, the type of neck dissection performed in patients with head and neck malignancy is finally determined by intraoperative assessment of clinically suspect lymph nodes by frozen section. This prospective study aimed to assess the accuracy of clinical intraoperative lymph node assessment and therefore to examine validity of the underlying assumption that the surgeon can consistently identify nodes that contain metastatic tumor. We also aimed to assess whether gross morphological characteristics of the lymph nodes examined could be correlated with nodal status and therefore used to predict those nodes containing metastatic disease.Study Design A prospective study assessing the accuracy of clinical intraoperative lymph node assessment in the node‐negative neck.Methods Forty‐six neck dissections from 34 patients with head and neck cancer were prospectively examined intraoperatively by a single surgeon. All obvious nodes were clinically assessed, morphologically described, and subsequently correlated with pathological findings.Results Sixty palpable nodes were identified in 32 neck dissections. They were clinically categorized as malignant or suspect (22) or benign (38). Pathological examination revealed a false‐positive rate of 30% and a false‐negative rate of 44%. The sensitivity of intraoperative lymph node assessment was 56%, and the specificity was 70%. Apart from “infiltration,” morphological characteristics could not be correlated with nodal status. In the 14 neck dissections with no obviously palpable lymph nodes, 4 (29%) were positive for metastatic disease.Conclusions In the node‐negative neck, intraoperative assessment does not seem to improve the accuracy of staging. The only parameter of benefit and correlating with metastatic disease is clinical evidence of infiltration. The assumption that frozen section is a good determinate for selection of type of neck dissection is questionable. If selective neck dissection is not found to be therapeutic, its use leads to over‐reliance on other therapeutic treatment such as postoperative radiotherapy, depriving the patient of a potential useful treatment modality in cases of locoregional recurrence.

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Research paper thumbnail of Laryngeal tuberculosis: an important diagnosis

Journal of Laryngology and Otology, Nov 1, 2000

The incidence of laryngeal tuberculosis is increasing worldwide. To ensure early diagnosis it is ... more The incidence of laryngeal tuberculosis is increasing worldwide. To ensure early diagnosis it is important for physicians and otolaryngologists to recognize its cardinal signs and symptoms. We present two recent cases of laryngeal tuberculosis that presented to our department. We outline potential pitfalls in diagnosis, and highlight the importance of obtaining a tissue diagnosis. The literature is reviewed, and the treatment options outlined.

Bookmarks Related papers MentionsView impact

Research paper thumbnail of Incidence of sinusitis after orbital decompression

Otolaryngology-Head and Neck Surgery, Aug 1, 1997

Bookmarks Related papers MentionsView impact

Research paper thumbnail of Endolaryngeal cysts presenting with acute respiratory distress*

Clinical otolaryngology and allied sciences, Oct 1, 2004

This is a retrospective review of benign cysts of the adult endolarynx that presented as airway e... more This is a retrospective review of benign cysts of the adult endolarynx that presented as airway emergencies in four teaching hospitals of Dublin, Ireland, over 2 years. During that period nine patients with endolaryngeal cysts necessitating emergency airway intervention were managed. All cases were treated by endoscopic microlaryngeal marsupialization after securing the airway either at the same time or as a staged procedure. Four of these patients required tracheostomies, one performed under local anaesthesia and the others after initial endotracheal intubation. Definitive treatment was carried out in six cases at initial endoscopic diagnosis. Three of the tracheostomized patients had a staged management, two because of their medical status and one for further investigations. On the basis of our findings we suggest that all benign cysts around the endolarynx should simply be called &#39;endolaryngeal cysts&#39; instead of the current practice of trying to classify them into various histological and morphological types with no prognostic or management differences. Benign cysts of the endolarynx presenting with airway obstruction would appear to be more frequent than is generally maintained in the literature.

Bookmarks Related papers MentionsView impact

Research paper thumbnail of An unusual Case of External Ear Inflammation Caused by Sarcoidosis

Ear, nose, & throat journal, Dec 1, 2003

Bookmarks Related papers MentionsView impact

Research paper thumbnail of Surgical management of lymphangiomas in adults

Journal of Laryngology and Otology, Jun 1, 1996

Lymphangiomas are uncommon benign congenital tumours. Most occur in the head and neck region and ... more Lymphangiomas are uncommon benign congenital tumours. Most occur in the head and neck region and the vast majority present before the age of two. This paper describes the presentation and management of four cases presenting after puberty and involving the parotid gland. The cases are unusual in that all were intimately associated with the facial nerve and in an older population. The value of selective neck dissection and facial nerve exposure as an approach to these lesions is discussed.

Bookmarks Related papers MentionsView impact

Research paper thumbnail of Role of human papillomavirus in oropharyngeal squamous cell carcinoma: A review

World Journal of Clinical Cases, 2014

Bookmarks Related papers MentionsView impact

Research paper thumbnail of The Westaby T-Y tracheobronchial stent in otolaryngology

Journal of Laryngology and Otology, Jul 1, 1999

Bookmarks Related papers MentionsView impact

Research paper thumbnail of Facial node involvement in head and neck cancer

Head & neck, 2004

Bookmarks Related papers MentionsView impact

Research paper thumbnail of Head and neck schwannomas – a 10 year review

Journal of Laryngology and Otology, Feb 1, 2000

Schwannomas of the head and neck are uncommon tumours that arise from any peripheral, cranial or ... more Schwannomas of the head and neck are uncommon tumours that arise from any peripheral, cranial or autonomic nerve. Twenty-five to 45 per cent of extracranial schwannomas occur in the head and neck region and thus are usually in the domain of the otolaryngologist. They usually present insidiously and thus are often diagnosed incorrectly or after lengthy delays, however, better imaging and cytological techniques have lessened this to some degree more recently. For benign lesions conservative surgical excision is the treatment of choice bearing in mind possible vagal or sympathetic chain injury. Malignant schwannomas are best treated with wide excision where possible. The role of adjuvant therapy remains uncertain and irrespective of treatment modality prognosis is poor with an overall survival of 15 per cent. However, recent advances in ras oncogene inhibitors may hold hope for the future.

Bookmarks Related papers MentionsView impact

Research paper thumbnail of AB0642 Otolaryngeal Manifestations of Behçet's Disease in a Northern European Population

Annals of the Rheumatic Diseases, Jun 1, 2015

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Research paper thumbnail of Lingual granuloma of pregnancy

Revue de laryngologie - otologie - rhinologie, 2008

Pyogenic granuloma gravidarum is a rare condition. There have been very few reports in the litera... more Pyogenic granuloma gravidarum is a rare condition. There have been very few reports in the literature of these tumours affecting the tongue. We describe a case of pyogenic granuloma occurring on the tongue of a female who was 32 weeks pregnant. We present the clinical and histopathological features of this rare condition, discuss treatment options and review current literature.

Bookmarks Related papers MentionsView impact