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Clinical Nutrition, 2005
Background and aims: Evaluate the influence of tomato powder in diets differing in energy level o... more Background and aims: Evaluate the influence of tomato powder in diets differing in energy level on antioxidant status in blood and liver of rats. Methods: Twenty-four adult male Wistar rats weighing 150-180 g were placed four groups (n ¼ 6). For 28 days, animals were fed a diet that was either hyper energetic or hypo energetic. Some diets were supplemented with tomato powder. Liver and blood were collected for analysis of antioxidant enzymes, non-enzymatic antioxidants, thiobarbituric acid reactive species, ubiquinol 9, a-tocopherol, lycopene and b-carotene. Data were analysed by two-way ANOVA. Results: Food intake and thiobarbituric acid-reactive substances contents in liver and plasma were significantly decreased by tomato powder at both energy levels. After tomato powder supplementation, the hepatic levels of ubiquinol 9, a-tocopherol, lycopene and b-carotene were significantly enhanced. In plasma, only the contents of lycopene and b-carotene were enhanced. The erythrocytic and hepatic activities of catalase were lower, while those of glutathione peroxidase were higher after the ingestion of tomato powder. Total and reduced glutathione contents in liver showed lower levels in cafeteria-fed rats compared to the hypo energetic diet. (E.A.M. Moreira).
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Clinical Nutrition, 2005
Background and aims: Evaluate the influence of tomato powder in diets differing in energy level o... more Background and aims: Evaluate the influence of tomato powder in diets differing in energy level on antioxidant status in blood and liver of rats. Methods: Twenty-four adult male Wistar rats weighing 150-180 g were placed four groups (n ¼ 6). For 28 days, animals were fed a diet that was either hyper energetic or hypo energetic. Some diets were supplemented with tomato powder. Liver and blood were collected for analysis of antioxidant enzymes, non-enzymatic antioxidants, thiobarbituric acid reactive species, ubiquinol 9, a-tocopherol, lycopene and b-carotene. Data were analysed by two-way ANOVA. Results: Food intake and thiobarbituric acid-reactive substances contents in liver and plasma were significantly decreased by tomato powder at both energy levels. After tomato powder supplementation, the hepatic levels of ubiquinol 9, a-tocopherol, lycopene and b-carotene were significantly enhanced. In plasma, only the contents of lycopene and b-carotene were enhanced. The erythrocytic and hepatic activities of catalase were lower, while those of glutathione peroxidase were higher after the ingestion of tomato powder. Total and reduced glutathione contents in liver showed lower levels in cafeteria-fed rats compared to the hypo energetic diet. (E.A.M. Moreira).
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