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Papers by Ibrahima DIALLO

Understanding how external pressures impact ecosystem structure and functioning is essential for ... more Understanding how external pressures impact ecosystem structure and functioning is essential for ecosystem based
approaches to fisheries management. We quantified the relative effects of fisheries exploitation and environmental
conditions on ecological indicators derived from two different data sources, fisheries catch data (catch-based) and fisheries independent survey data (survey-based) for 12 marine ecosystems using a partial least squares path modeling approach (PLS-PM). We linked these ecological indicators to the total biomass of the ecosystem. Although the effects of exploitation and environmental conditions differed across the ecosystems,
some general results can be drawn from the comparative approach. Interestingly, the PLS-PM analyses showed
that survey-based indicators were less tightly associated with each other than the catch-based ones. The analyses
also showed that the effects of environmental conditions on the ecological indicators were predominantly significant,
and tended to be negative, suggesting that in the recent period, indicators accounted for changes in environmental
conditions and the changes were more likely to be adverse. Total biomass was associated with fisheries exploitation and environmental conditions; however its association with the ecological indicators was weak across the ecosystems. Knowledge of the relative influence of exploitation and environmental pressures on the dynamics within exploited ecosystems will help us to move towards ecosystem-based approaches to fisheries management. PLS-PM proved to be a useful approach to quantify the relative effects of fisheries exploitation and environmental conditions and suggest it could be used more widely in fisheries oceanography.

ABSTRACT This paper is an overview of the interface between Islamic and western pedagogies and ep... more ABSTRACT This paper is an overview of the interface between Islamic and western pedagogies and epistemologies in Muslim context. It shows that despite differences in pedagogies and epistemologies, education in both Islamic and western contexts were important domains in religious organisations. However, in Europe, the powerful rise and the strengthening of secular and rationalist philosophies and ideologies shrank significantly the scope and the influences of religious knowledge in public education and knowledge. In contrast, Islamic education and knowledge have remained strongly attached to Qur’anic framework which has impacted on its pedagogies and epistemologies. Evolving on these parallel paths has resulted in noticeable divergences accounted for by differences in tradition and directions.

Bulletin De Liaison Laboratoire D Anthropologie Juridique De Paris, 1999

Journal of Tumor, Jun 1, 2013

JAMA Ophthalmology, 2016

Few studies have been published on the association of the radiation dose received to the eyes dur... more Few studies have been published on the association of the radiation dose received to the eyes during radiotherapy (RT) for childhood cancer and the risk for later cataract. To investigate the risk for cataract after treatment of nonretinoblastoma solid cancer in childhood. The study used data from the Euro2K cohort that includes 4389 5-year survivors of solid tumors treated from January 1, 1945, to December 31, 1985; of these, 3172 patients were treated in France. A self-reported questionnaire was sent to French survivors from September 1, 2005, to December 31, 2012, when follow-up was considered completed for this study. However, 619 patients died before the beginning of the study and 128 patients treated for a retinoblastoma or who underwent enucleation were excluded. Likewise, 429 patients with unknown addresses or who did not return the consent form and 163 nonresponders did not participate. The remaining 1833 patients who completed the questionnaire underwent analysis for this study from June 1, 2014, to December 7, 2015. Radiation doses in both eyes for individuals were estimated for all patients who had received RT. The role of the radiation dose in cataract risk was investigated using the Cox proportional hazard regression model and the excess relative or the absolute risk model. The role of ctytotoxic chemotherapy was also investigated. The 1833 patients (961 men [52.4%]; 872 women [47.6%]; mean [SD] age, 37.0 [8.5]) who returned the questionnaire were included in the analysis. After a mean follow-up of 32 years, 33 patients with unilateral or bilateral cataract were identified, for a total of 47 cataract events. The 47 events were validated by medical record review and by contacting the patients and the corresponding medical physician or ophthalmologist to obtain copies of diagnostic examinations or surgical reports. Overall, in a multivariable Cox proportional hazard regression analysis, patients who received RT had a 4.4-fold (95% CI, 1.5- to 13.0-fold) increased risk for cataract compared with patients who did not receive RT. Exposure to radiation doses of at least 10 Gy to the eyes increased the hazard ratio 39-fold (95% CI, 12.0- to 127.9-fold), relative to no radiation exposure. Although based on few patients, a strong increase in cataract risk (hazard ratio, 26.3; 95% CI, 7.1-96.6) was observed in patients treated with melphalan hydrochloride. This study can inform guideline-based recommendations for long-term follow-up for cataract.

Nordic Journal of African Studies, 2009

Journal of Gastroenterology and Hepatology Research

Pan African Medical Journal

Circulation, Jan 20, 2015

-Cardiac disease (CD) is one of the major side effects of childhood cancer therapy, but until now... more -Cardiac disease (CD) is one of the major side effects of childhood cancer therapy, but until now little has been known about the relationship between heart radiation dose (HRD) received during childhood and risk of CD. -The cohort comprised 3162 five-year survivors of childhood cancer. Chemotherapy information was collected and HRD was estimated. There were 347 CDs in 234 patients, 156 of them rated grade ≥3. Cox's and Poisson regression models were used. The cumulative incidence of any type of CD at 40 years of age was 11•0% (95%CI: 9•5-12•7) and 7•4% (95%CI: 6•2-8•9) when only the CDs of grade 3 or more were considered. Compared to patients who received no anthracycline and either no radiotherapy or an HRD<0•1Gy, the risk was multiplied by 18•4 (95%CI: 7•1-48•0) in patients who had received anthracycline and no radiotherapy or an HRD <0•1Gy, by 60•4 (95%CI: 22•4-163•0) in those who had received no anthracycline and an HRD ≥30Gy, and 61•5 (95%CI: 19•6-192•8) in those who had received both anthracycline and an HRD ≥30Gy. -Survivors of childhood cancers treated with radiotherapy and/or anthracycline run a high dose-dependent risk of developing CD. CDs develop earlier in patients treated with anthracycline than in those treated without it.

The Journal of Clinical Endocrinology & Metabolism, 2015

Context: Thyroid carcinoma is a frequent complication of childhood cancer radiotherapy. The dose-... more Context: Thyroid carcinoma is a frequent complication of childhood cancer radiotherapy. The dose-response to thyroid radiation dose is now well established, but the potential modifier effect of other factors still requires further investigation.

International Journal of Radiation Oncology*Biology*Physics, 2015

To investigate the roles of radiation therapy and chemotherapy in the occurrence of subsequent le... more To investigate the roles of radiation therapy and chemotherapy in the occurrence of subsequent leukemia after childhood cancer. We analyzed data from a case-control study with 35 cases and 140 controls. The active bone marrow (ABM) was segmented into 19 compartments, and the radiation dose was estimated in each. The chemotherapy drug doses were also estimated to enable adjustments. Models capable of accounting for radiation dose heterogeneity were implemented for analysis. Univariate analysis showed a significant trend in the increase of secondary leukemia risk with radiation dose, after accounting for dose heterogeneity (P=.046). This trend became nonsignificant after adjustment for doses of epipodophyllotoxins, alkylating agents, and platinum compounds and the first cancer on multivariate analysis (P=.388). The role of the radiation dose appeared to be dwarfed, mostly by the alkylating agents (odds ratio 6.9, 95% confidence interval 1.9-25.0). Among the patients who have received >16 Gy to the ABM, the radiogenic risk of secondary leukemia was about 4 times greater in the subgroup with no alkylating agents than in the subgroup receiving ≥10 g/m(2). Notwithstanding the limitations resulting from the size of our study population and the quite systematic co-treatment with chemotherapy, the use of detailed information on the radiation dose distribution to ABM enabled consideration of the role of radiation therapy in secondary leukemia induction after childhood cancer.

The Journal of Urology, 2015

Kidney carcinoma (KC) is a rare second malignant carcinoma following childhood cancer. In order t... more Kidney carcinoma (KC) is a rare second malignant carcinoma following childhood cancer. In order to quantify the risk of KC following childhood cancer treatment, and to assess its risk factors, we followed over 27 years on average, a cohort of 4,350 5-year childhood cancer survivors treated between 1943 and 1985, in France and UK. Radiation dose received to the two kidneys during radiotherapy was estimated with dedicated software whatever the site of the childhood cancer. Thirteen patients had developed a KC. The cumulative incidence of KC was 0.62% (95%CI: 0.27% - 1.45%), 40 years after diagnosis, i.e. 13.3-fold higher (95%CI: 7.1-22.3) than that expected in the general population. The absolute excess risk strongly increased (p<0.0001) with longer duration of follow-up. Compared to the general population, the incidence of KC was 5.7-fold higher (95%CI: 1.4-14.7) if no radiation therapy or less than 1 Gy had been absorbed by the kidney, but 66.3-fold higher (95%CI: 23.8-142.5) if the radiation dose to the kidneys was between 10 and 19 Gy, and 14.5-fold greater (95%CI: 0.8-63.9) for higher radiation doses to the kidney. Treatment with chemotherapy increased the risk of KC (RR=5.1, 95%CI: 1.1-22.7), but we were not able to identify a specific drug or drug category responsive for this increase. Moderate radiation dose to the kidneys during childhood cancer treatment increased the risk of a second KC whose incidence will be on the increase when childhood cancer survivors reach old ages.

Revue d'Épidémiologie et de Santé Publique, 2006

Radiation and environmental biophysics, Jan 18, 2015

Analyses of the Life Span Study (LSS) of Japanese atomic bombing survivors have routinely incorpo... more Analyses of the Life Span Study (LSS) of Japanese atomic bombing survivors have routinely incorporated corrections for additive classical measurement errors using regression calibration. Recently, several studies reported that the efficiency of the simulation-extrapolation method (SIMEX) is slightly more accurate than the simple regression calibration method (RCAL). In the present paper, the SIMEX and RCAL methods have been used to address errors in atomic bomb survivor dosimetry on solid cancer and leukaemia mortality risk estimates. For instance, it is shown that using the SIMEX method, the ERR/Gy is increased by an amount of about 29 % for all solid cancer deaths using a linear model compared to the RCAL method, and the corrected EAR 10(-4) person-years at 1 Gy (the linear terms) is decreased by about 8 %, while the corrected quadratic term (EAR 10(-4) person-years/Gy(2)) is increased by about 65 % for leukaemia deaths based on a linear-quadratic model. The results with SIMEX met...

Cancer/Radiothérapie, 2007

Understanding how external pressures impact ecosystem structure and functioning is essential for ... more Understanding how external pressures impact ecosystem structure and functioning is essential for ecosystem based
approaches to fisheries management. We quantified the relative effects of fisheries exploitation and environmental
conditions on ecological indicators derived from two different data sources, fisheries catch data (catch-based) and fisheries independent survey data (survey-based) for 12 marine ecosystems using a partial least squares path modeling approach (PLS-PM). We linked these ecological indicators to the total biomass of the ecosystem. Although the effects of exploitation and environmental conditions differed across the ecosystems,
some general results can be drawn from the comparative approach. Interestingly, the PLS-PM analyses showed
that survey-based indicators were less tightly associated with each other than the catch-based ones. The analyses
also showed that the effects of environmental conditions on the ecological indicators were predominantly significant,
and tended to be negative, suggesting that in the recent period, indicators accounted for changes in environmental
conditions and the changes were more likely to be adverse. Total biomass was associated with fisheries exploitation and environmental conditions; however its association with the ecological indicators was weak across the ecosystems. Knowledge of the relative influence of exploitation and environmental pressures on the dynamics within exploited ecosystems will help us to move towards ecosystem-based approaches to fisheries management. PLS-PM proved to be a useful approach to quantify the relative effects of fisheries exploitation and environmental conditions and suggest it could be used more widely in fisheries oceanography.

ABSTRACT This paper is an overview of the interface between Islamic and western pedagogies and ep... more ABSTRACT This paper is an overview of the interface between Islamic and western pedagogies and epistemologies in Muslim context. It shows that despite differences in pedagogies and epistemologies, education in both Islamic and western contexts were important domains in religious organisations. However, in Europe, the powerful rise and the strengthening of secular and rationalist philosophies and ideologies shrank significantly the scope and the influences of religious knowledge in public education and knowledge. In contrast, Islamic education and knowledge have remained strongly attached to Qur’anic framework which has impacted on its pedagogies and epistemologies. Evolving on these parallel paths has resulted in noticeable divergences accounted for by differences in tradition and directions.

Bulletin De Liaison Laboratoire D Anthropologie Juridique De Paris, 1999

Journal of Tumor, Jun 1, 2013

JAMA Ophthalmology, 2016

Few studies have been published on the association of the radiation dose received to the eyes dur... more Few studies have been published on the association of the radiation dose received to the eyes during radiotherapy (RT) for childhood cancer and the risk for later cataract. To investigate the risk for cataract after treatment of nonretinoblastoma solid cancer in childhood. The study used data from the Euro2K cohort that includes 4389 5-year survivors of solid tumors treated from January 1, 1945, to December 31, 1985; of these, 3172 patients were treated in France. A self-reported questionnaire was sent to French survivors from September 1, 2005, to December 31, 2012, when follow-up was considered completed for this study. However, 619 patients died before the beginning of the study and 128 patients treated for a retinoblastoma or who underwent enucleation were excluded. Likewise, 429 patients with unknown addresses or who did not return the consent form and 163 nonresponders did not participate. The remaining 1833 patients who completed the questionnaire underwent analysis for this study from June 1, 2014, to December 7, 2015. Radiation doses in both eyes for individuals were estimated for all patients who had received RT. The role of the radiation dose in cataract risk was investigated using the Cox proportional hazard regression model and the excess relative or the absolute risk model. The role of ctytotoxic chemotherapy was also investigated. The 1833 patients (961 men [52.4%]; 872 women [47.6%]; mean [SD] age, 37.0 [8.5]) who returned the questionnaire were included in the analysis. After a mean follow-up of 32 years, 33 patients with unilateral or bilateral cataract were identified, for a total of 47 cataract events. The 47 events were validated by medical record review and by contacting the patients and the corresponding medical physician or ophthalmologist to obtain copies of diagnostic examinations or surgical reports. Overall, in a multivariable Cox proportional hazard regression analysis, patients who received RT had a 4.4-fold (95% CI, 1.5- to 13.0-fold) increased risk for cataract compared with patients who did not receive RT. Exposure to radiation doses of at least 10 Gy to the eyes increased the hazard ratio 39-fold (95% CI, 12.0- to 127.9-fold), relative to no radiation exposure. Although based on few patients, a strong increase in cataract risk (hazard ratio, 26.3; 95% CI, 7.1-96.6) was observed in patients treated with melphalan hydrochloride. This study can inform guideline-based recommendations for long-term follow-up for cataract.

Nordic Journal of African Studies, 2009

Journal of Gastroenterology and Hepatology Research

Pan African Medical Journal

Circulation, Jan 20, 2015

-Cardiac disease (CD) is one of the major side effects of childhood cancer therapy, but until now... more -Cardiac disease (CD) is one of the major side effects of childhood cancer therapy, but until now little has been known about the relationship between heart radiation dose (HRD) received during childhood and risk of CD. -The cohort comprised 3162 five-year survivors of childhood cancer. Chemotherapy information was collected and HRD was estimated. There were 347 CDs in 234 patients, 156 of them rated grade ≥3. Cox's and Poisson regression models were used. The cumulative incidence of any type of CD at 40 years of age was 11•0% (95%CI: 9•5-12•7) and 7•4% (95%CI: 6•2-8•9) when only the CDs of grade 3 or more were considered. Compared to patients who received no anthracycline and either no radiotherapy or an HRD<0•1Gy, the risk was multiplied by 18•4 (95%CI: 7•1-48•0) in patients who had received anthracycline and no radiotherapy or an HRD <0•1Gy, by 60•4 (95%CI: 22•4-163•0) in those who had received no anthracycline and an HRD ≥30Gy, and 61•5 (95%CI: 19•6-192•8) in those who had received both anthracycline and an HRD ≥30Gy. -Survivors of childhood cancers treated with radiotherapy and/or anthracycline run a high dose-dependent risk of developing CD. CDs develop earlier in patients treated with anthracycline than in those treated without it.

The Journal of Clinical Endocrinology & Metabolism, 2015

Context: Thyroid carcinoma is a frequent complication of childhood cancer radiotherapy. The dose-... more Context: Thyroid carcinoma is a frequent complication of childhood cancer radiotherapy. The dose-response to thyroid radiation dose is now well established, but the potential modifier effect of other factors still requires further investigation.

International Journal of Radiation Oncology*Biology*Physics, 2015

To investigate the roles of radiation therapy and chemotherapy in the occurrence of subsequent le... more To investigate the roles of radiation therapy and chemotherapy in the occurrence of subsequent leukemia after childhood cancer. We analyzed data from a case-control study with 35 cases and 140 controls. The active bone marrow (ABM) was segmented into 19 compartments, and the radiation dose was estimated in each. The chemotherapy drug doses were also estimated to enable adjustments. Models capable of accounting for radiation dose heterogeneity were implemented for analysis. Univariate analysis showed a significant trend in the increase of secondary leukemia risk with radiation dose, after accounting for dose heterogeneity (P=.046). This trend became nonsignificant after adjustment for doses of epipodophyllotoxins, alkylating agents, and platinum compounds and the first cancer on multivariate analysis (P=.388). The role of the radiation dose appeared to be dwarfed, mostly by the alkylating agents (odds ratio 6.9, 95% confidence interval 1.9-25.0). Among the patients who have received >16 Gy to the ABM, the radiogenic risk of secondary leukemia was about 4 times greater in the subgroup with no alkylating agents than in the subgroup receiving ≥10 g/m(2). Notwithstanding the limitations resulting from the size of our study population and the quite systematic co-treatment with chemotherapy, the use of detailed information on the radiation dose distribution to ABM enabled consideration of the role of radiation therapy in secondary leukemia induction after childhood cancer.

The Journal of Urology, 2015

Kidney carcinoma (KC) is a rare second malignant carcinoma following childhood cancer. In order t... more Kidney carcinoma (KC) is a rare second malignant carcinoma following childhood cancer. In order to quantify the risk of KC following childhood cancer treatment, and to assess its risk factors, we followed over 27 years on average, a cohort of 4,350 5-year childhood cancer survivors treated between 1943 and 1985, in France and UK. Radiation dose received to the two kidneys during radiotherapy was estimated with dedicated software whatever the site of the childhood cancer. Thirteen patients had developed a KC. The cumulative incidence of KC was 0.62% (95%CI: 0.27% - 1.45%), 40 years after diagnosis, i.e. 13.3-fold higher (95%CI: 7.1-22.3) than that expected in the general population. The absolute excess risk strongly increased (p<0.0001) with longer duration of follow-up. Compared to the general population, the incidence of KC was 5.7-fold higher (95%CI: 1.4-14.7) if no radiation therapy or less than 1 Gy had been absorbed by the kidney, but 66.3-fold higher (95%CI: 23.8-142.5) if the radiation dose to the kidneys was between 10 and 19 Gy, and 14.5-fold greater (95%CI: 0.8-63.9) for higher radiation doses to the kidney. Treatment with chemotherapy increased the risk of KC (RR=5.1, 95%CI: 1.1-22.7), but we were not able to identify a specific drug or drug category responsive for this increase. Moderate radiation dose to the kidneys during childhood cancer treatment increased the risk of a second KC whose incidence will be on the increase when childhood cancer survivors reach old ages.

Revue d'Épidémiologie et de Santé Publique, 2006

Radiation and environmental biophysics, Jan 18, 2015

Analyses of the Life Span Study (LSS) of Japanese atomic bombing survivors have routinely incorpo... more Analyses of the Life Span Study (LSS) of Japanese atomic bombing survivors have routinely incorporated corrections for additive classical measurement errors using regression calibration. Recently, several studies reported that the efficiency of the simulation-extrapolation method (SIMEX) is slightly more accurate than the simple regression calibration method (RCAL). In the present paper, the SIMEX and RCAL methods have been used to address errors in atomic bomb survivor dosimetry on solid cancer and leukaemia mortality risk estimates. For instance, it is shown that using the SIMEX method, the ERR/Gy is increased by an amount of about 29 % for all solid cancer deaths using a linear model compared to the RCAL method, and the corrected EAR 10(-4) person-years at 1 Gy (the linear terms) is decreased by about 8 %, while the corrected quadratic term (EAR 10(-4) person-years/Gy(2)) is increased by about 65 % for leukaemia deaths based on a linear-quadratic model. The results with SIMEX met...

Cancer/Radiothérapie, 2007