Daem Roshani - Academia.edu (original) (raw)

Papers by Daem Roshani

Research paper thumbnail of Survival of Patients with Stomach Cancer and its Determinants in Kurdistan

Research paper thumbnail of Prevalence and trend of hepatitis C virus infection among blood donors in Iran: A systematic review and meta-analysis

Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences, 2013

Hepatitis C virus (HCV) is the main causative agent of post-transfusion hepatitis. The virus is d... more Hepatitis C virus (HCV) is the main causative agent of post-transfusion hepatitis. The virus is distributed worldwide with varying prevalence in different countries, which could easily lead to chronic infections, cirrhosis, and even hepatocellular carcinoma. The aim of this study was to investigate prevalence of HCV infection and its trend in Iranian blood donors. Literatures on the HCV prevalence among blood donors in Iran were acquired through searching PubMed, Magiran, IranMedex, Scientific Information Databank, and Google databases. All the potentially relevant papers were reviewed independently by two investigators by assessing the eligibility of each paper and abstracting data. Prevalence was calculated using random effects model for meta-analysis. Forty-eight studies with total samples of 10,739,221 persons from 1996 to 2011 were combined and meta-analyzed, the pooled prevalence of HCV infection among blood donors in Iran provinces and cities was 0.5% (95% CI: 0.4-0.6%). Tren...

Research paper thumbnail of Prevalence and trend of hepatitis C virus infection among blood donors in Iran: A systematic review and meta-analysis

Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences, 2013

Hepatitis C virus (HCV) is the main causative agent of post-transfusion hepatitis. The virus is d... more Hepatitis C virus (HCV) is the main causative agent of post-transfusion hepatitis. The virus is distributed worldwide with varying prevalence in different countries, which could easily lead to chronic infections, cirrhosis, and even hepatocellular carcinoma. The aim of this study was to investigate prevalence of HCV infection and its trend in Iranian blood donors. Literatures on the HCV prevalence among blood donors in Iran were acquired through searching PubMed, Magiran, IranMedex, Scientific Information Databank, and Google databases. All the potentially relevant papers were reviewed independently by two investigators by assessing the eligibility of each paper and abstracting data. Prevalence was calculated using random effects model for meta-analysis. Forty-eight studies with total samples of 10,739,221 persons from 1996 to 2011 were combined and meta-analyzed, the pooled prevalence of HCV infection among blood donors in Iran provinces and cities was 0.5% (95% CI: 0.4-0.6%). Tren...

Research paper thumbnail of The chemokine receptor CXCR4 is associated with the staging of gastric cancer

Advanced Biomedical Research, 2014

Background: CXCR4 is the cognitive receptor for stromal-derived factor-1 (SDF-1) and has been pre... more Background: CXCR4 is the cognitive receptor for stromal-derived factor-1 (SDF-1) and has been previously shown to be associated with tumor growth and invasion of many cancers. However, its expression and function in gastric cancer has not been well clarified. Materials and Methods: Herein, we studied the expression of CXCR4 on gastric samples from patients with gastric adenocarcinoma in comparison with precancerous lesions by employing qRT-PCR. Results: Our qRT-PCR data show that CXCR4 is highly expressed in tissue samples from patients with gastric cancer than precancerous lesions (2.4 times higher, P value < 0.05). When we correlated the level of CXCR4 with clinicopathological findings, we observed that CXCR4 level is associated with staging of the disease and lymphatic invasion. In conclusion: We present evidence that CXCR4 level is significantly elevated in later stages of gastric cancer. Thus, CXCR4 may play a crucial role in gastric cancer progression.

Research paper thumbnail of Prevalence of Hepatitis C Virus Genotypes in Iranian Patients: a Systematic Review and Meta-Analysis

Hepatitis Monthly, 2014

Context : Hepatitis C virus (HCV) is a global public health problem and a major etiology of chron... more Context : Hepatitis C virus (HCV) is a global public health problem and a major etiology of chronic liver disease, which may develop into cirrhosis and hepatocellular carcinoma. Genotypes of HCV indicate the route of acquisition, the clinical outcome, response to treatment, prognosis and control strategies. Objectives: The aim of this study was to estimate the overall prevalence and trend of HCV genotypes or subtypes in Iran Data Sources: A literature review was done for papers reporting HCV genotypes in Iranian patients in PubMed, Magiran, IranMedex, Scientific Information Databank, and Google scholar databases. Study Selection: Data were selected according to inclusion and exclusion criteria. Data Extraction: Data were abstracted by two independent authors. Data were analyzed based on random-effects model using the Meta R. Pooled statistical software. Prevalence of HCV genotypes in cities and provinces of Iran with 95% confidence interval (CI) were calculated. Results: Fifty-three articles published between 1999 and 31 June 2014 including 22952 HCV infected individuals were included in the metaanalysis. Subtype 1a was predominant with a rate of 39% (95% CI: 34-44%); followed by subtype 3a, 32% (95% CI: 26-39%); subtype 1b, 13% (95% CI: 10-15%); genotype 4, 5.18% (95% CI: 3.27-7.5%); and genotype 2, 3.6% (95% CI: 1.6-8.3%). Untypeable HCV had a rate of 0.11% (95% CI: 0.07-0.16%).

Research paper thumbnail of Acute Flaccid Paralysis and Its Differential Diagnosis in in Kurdistan Province, Western Iran; an 11-Year Surveillance

Iranian journal of pediatrics, 2014

The surveillance of acute flaccid paralysis (AFP) is a key strategy for monitoring the progress o... more The surveillance of acute flaccid paralysis (AFP) is a key strategy for monitoring the progress of poliomyelitis eradication and is a sensitive measure for detecting potential cases of poliomyelitis and poliovirus infection. This study was conducted to describe the characteristics of patients reported with AFP, and to evaluate the performance of the surveillance system in Kurdistan province, western Iran, using indicators recommended by the World Health Organization (WHO). This observational study was conducted from January 2000 to December 2010 at the Kurdistan Center for Disease Control and the Department of Pediatrics. All children who fulfilled the WHO definition for AFP were included in our study. The stool samples of all the children were sent for poliovirus isolation. All the patients were evaluated for 60 days after the onset of symptoms to identify the signs of residual weakness. One-hundred thirty nine children aged <15 years were reported to the Center for Diseases Con...

Research paper thumbnail of Survival of Patients with Stomach Cancer and its Determinants in Kurdistan

Research paper thumbnail of Prevalence and trend of hepatitis C virus infection among blood donors in Iran: A systematic review and meta-analysis

Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences, 2013

Hepatitis C virus (HCV) is the main causative agent of post-transfusion hepatitis. The virus is d... more Hepatitis C virus (HCV) is the main causative agent of post-transfusion hepatitis. The virus is distributed worldwide with varying prevalence in different countries, which could easily lead to chronic infections, cirrhosis, and even hepatocellular carcinoma. The aim of this study was to investigate prevalence of HCV infection and its trend in Iranian blood donors. Literatures on the HCV prevalence among blood donors in Iran were acquired through searching PubMed, Magiran, IranMedex, Scientific Information Databank, and Google databases. All the potentially relevant papers were reviewed independently by two investigators by assessing the eligibility of each paper and abstracting data. Prevalence was calculated using random effects model for meta-analysis. Forty-eight studies with total samples of 10,739,221 persons from 1996 to 2011 were combined and meta-analyzed, the pooled prevalence of HCV infection among blood donors in Iran provinces and cities was 0.5% (95% CI: 0.4-0.6%). Tren...

Research paper thumbnail of Prevalence and trend of hepatitis C virus infection among blood donors in Iran: A systematic review and meta-analysis

Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences, 2013

Hepatitis C virus (HCV) is the main causative agent of post-transfusion hepatitis. The virus is d... more Hepatitis C virus (HCV) is the main causative agent of post-transfusion hepatitis. The virus is distributed worldwide with varying prevalence in different countries, which could easily lead to chronic infections, cirrhosis, and even hepatocellular carcinoma. The aim of this study was to investigate prevalence of HCV infection and its trend in Iranian blood donors. Literatures on the HCV prevalence among blood donors in Iran were acquired through searching PubMed, Magiran, IranMedex, Scientific Information Databank, and Google databases. All the potentially relevant papers were reviewed independently by two investigators by assessing the eligibility of each paper and abstracting data. Prevalence was calculated using random effects model for meta-analysis. Forty-eight studies with total samples of 10,739,221 persons from 1996 to 2011 were combined and meta-analyzed, the pooled prevalence of HCV infection among blood donors in Iran provinces and cities was 0.5% (95% CI: 0.4-0.6%). Tren...

Research paper thumbnail of The chemokine receptor CXCR4 is associated with the staging of gastric cancer

Advanced Biomedical Research, 2014

Background: CXCR4 is the cognitive receptor for stromal-derived factor-1 (SDF-1) and has been pre... more Background: CXCR4 is the cognitive receptor for stromal-derived factor-1 (SDF-1) and has been previously shown to be associated with tumor growth and invasion of many cancers. However, its expression and function in gastric cancer has not been well clarified. Materials and Methods: Herein, we studied the expression of CXCR4 on gastric samples from patients with gastric adenocarcinoma in comparison with precancerous lesions by employing qRT-PCR. Results: Our qRT-PCR data show that CXCR4 is highly expressed in tissue samples from patients with gastric cancer than precancerous lesions (2.4 times higher, P value < 0.05). When we correlated the level of CXCR4 with clinicopathological findings, we observed that CXCR4 level is associated with staging of the disease and lymphatic invasion. In conclusion: We present evidence that CXCR4 level is significantly elevated in later stages of gastric cancer. Thus, CXCR4 may play a crucial role in gastric cancer progression.

Research paper thumbnail of Prevalence of Hepatitis C Virus Genotypes in Iranian Patients: a Systematic Review and Meta-Analysis

Hepatitis Monthly, 2014

Context : Hepatitis C virus (HCV) is a global public health problem and a major etiology of chron... more Context : Hepatitis C virus (HCV) is a global public health problem and a major etiology of chronic liver disease, which may develop into cirrhosis and hepatocellular carcinoma. Genotypes of HCV indicate the route of acquisition, the clinical outcome, response to treatment, prognosis and control strategies. Objectives: The aim of this study was to estimate the overall prevalence and trend of HCV genotypes or subtypes in Iran Data Sources: A literature review was done for papers reporting HCV genotypes in Iranian patients in PubMed, Magiran, IranMedex, Scientific Information Databank, and Google scholar databases. Study Selection: Data were selected according to inclusion and exclusion criteria. Data Extraction: Data were abstracted by two independent authors. Data were analyzed based on random-effects model using the Meta R. Pooled statistical software. Prevalence of HCV genotypes in cities and provinces of Iran with 95% confidence interval (CI) were calculated. Results: Fifty-three articles published between 1999 and 31 June 2014 including 22952 HCV infected individuals were included in the metaanalysis. Subtype 1a was predominant with a rate of 39% (95% CI: 34-44%); followed by subtype 3a, 32% (95% CI: 26-39%); subtype 1b, 13% (95% CI: 10-15%); genotype 4, 5.18% (95% CI: 3.27-7.5%); and genotype 2, 3.6% (95% CI: 1.6-8.3%). Untypeable HCV had a rate of 0.11% (95% CI: 0.07-0.16%).

Research paper thumbnail of Acute Flaccid Paralysis and Its Differential Diagnosis in in Kurdistan Province, Western Iran; an 11-Year Surveillance

Iranian journal of pediatrics, 2014

The surveillance of acute flaccid paralysis (AFP) is a key strategy for monitoring the progress o... more The surveillance of acute flaccid paralysis (AFP) is a key strategy for monitoring the progress of poliomyelitis eradication and is a sensitive measure for detecting potential cases of poliomyelitis and poliovirus infection. This study was conducted to describe the characteristics of patients reported with AFP, and to evaluate the performance of the surveillance system in Kurdistan province, western Iran, using indicators recommended by the World Health Organization (WHO). This observational study was conducted from January 2000 to December 2010 at the Kurdistan Center for Disease Control and the Department of Pediatrics. All children who fulfilled the WHO definition for AFP were included in our study. The stool samples of all the children were sent for poliovirus isolation. All the patients were evaluated for 60 days after the onset of symptoms to identify the signs of residual weakness. One-hundred thirty nine children aged <15 years were reported to the Center for Diseases Con...