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The aim of this study was to measure the body electrolytes (in plasma) such as sodium (Na +) and ... more The aim of this study was to measure the body electrolytes (in plasma) such as sodium (Na +) and potassium (k +) in adult sickle cell patients with genotype (HbSS) genotype and compare with controls normal with (HbAA) genotype. The study involved a total of 38 individuals, both males and females in the age range of 16-40 years. There were 3 study groups; steady state group, crisis state group and control group. Flame photometry was used to analyze sodium and potassium. In the males there was a statistically significant reduction in the concentration of sodium in both the steady state (129.40 ± 1.462) and crisis state (121.60 ± 0.678) when compared with control group (134.40 ± 2.040). Also, there was a statistically significant increase (P < 0.05) in the concentration of potassium in both the steady state (4.58 ± 0.171 mmol/l) and crisis state (4.66 ± 0.154 mmol/l) when compared with normal group (3.50 ± 0.172 mmol/l). The regular measurement of plasma sodium and potassium is, therefore, necessary in the management of the sickle cell disease patients.
The aim of this study was to measure the body electrolytes (in plasma) such as sodium (Na +) and ... more The aim of this study was to measure the body electrolytes (in plasma) such as sodium (Na +) and potassium (k +) in adult sickle cell patients with genotype (HbSS) genotype and compare with controls normal with (HbAA) genotype. The study involved a total of 38 individuals, both males and females in the age range of 16-40 years. There were 3 study groups; steady state group, crisis state group and control group. Flame photometry was used to analyze sodium and potassium. In the males there was a statistically significant reduction in the concentration of sodium in both the steady state (129.40 ± 1.462) and crisis state (121.60 ± 0.678) when compared with control group (134.40 ± 2.040). Also, there was a statistically significant increase (P < 0.05) in the concentration of potassium in both the steady state (4.58 ± 0.171 mmol/l) and crisis state (4.66 ± 0.154 mmol/l) when compared with normal group (3.50 ± 0.172 mmol/l). The regular measurement of plasma sodium and potassium is, therefore, necessary in the management of the sickle cell disease patients.