Suwarna Dangore - Academia.edu (original) (raw)

Papers by Suwarna Dangore

Zenodo (CERN European Organization for Nuclear Research), Sep 28, 2023

International Journal of Life Science and Pharma Research

Diabetes mellitus is a chronic metabolic disorder defined as an increase in sugar levels in the b... more Diabetes mellitus is a chronic metabolic disorder defined as an increase in sugar levels in the bloodstream brought onby either insufficient insulin secretion, resistance to insulin's effects, or both. All age groups are affected by the chronic conditionknown as diabetes mellitus. It is among the world's major causes of mortality and morbidity. Xerostomia, dental caries,periodontal disease, gingivitis, candidiasis, other oral infections, burning mouth syndrome, taste dysfunction, oral mucosalalterations, delayed wound healing, and localized osteitis are common oral manifestations of diabetes mellitus. Majorcomplications impacting a patient's quality of life include oral complications in diabetic individuals. Long-term oral problems inthese patients’ harm blood glucose regulation, making oral complications care and prevention important. The dental professionalshould be familiar with DM's oral manifestations to identify this disease complication. This article not only ...

European Journal of General Dentistry, Jan 17, 2024

Journal of pharmaceutical research international, Aug 25, 2021

Aims: The present study was undertaken to assess the knowledge, attitude and practice behaviors o... more Aims: The present study was undertaken to assess the knowledge, attitude and practice behaviors of parents towards care of the primary dentition of children in Wardha city, India.

Journal of Oral and Maxillofacial Pathology, 2022

Liver disease includes many diverse conditions that affect the morphology as well as function of ... more Liver disease includes many diverse conditions that affect the morphology as well as function of the liver and accounts for approximately two million deaths/year worldwide; one million due to complications of liver cirrhosis (LC) and one million due to viral hepatitis and hepatocellular carcinoma (HCC). [1,2] The etiology of liver disease is multi-factorial. However, the growing epidemiological evidence indicates that a number of risk factors like excessive alcohol drinking, hepatitis B and C infection, obesity, family history etc., modulate Background: Areca nut (AN) is one of the addictive substances known to cause deleterious effects on oral cavity as well as on various body organs including liver. But, scanty information is available reporting the adverse effects of AN chewing on the liver. Aim: To study the risk of liver disease in AN habitual based on the relevant published data. Methods: The literature search was performed by an electronic search of the PubMed/Medline, Scopus and Google Scholar databases using proper MESH headings and retrieved the articles published from 1998 to 2021. The eligibility criteria included: Human studies, AN habitual as study participants, use of controls and articles published in English. Data were extracted regarding characteristics of studies, characteristics of AN exposure, effect estimate and outcome of the studies. Results: Total 253 articles were identified from various databases and 15 studies were selected that met the inclusion criteria. Among these, thirteen studies showed an association between AN habit and attenuation of risk of liver disease as determined by relative risk/odds ratio/hazard ratio. Eleven studies described additive effect of AN and HBsAg and/or Anti hepatitis C virus status on development of liver disease. However, two of the studies showed opposite results. The heterogeneity in the study designs, exposure characteristics, outcomes and confounders precluded further meta-analysis. Conclusion: The association between AN chewing and an increased risk of developing liver disease is noted which necessitates the need for AN cessation campaign.

Areca nut (AN) consumption is a practice of great antiquity in India and reported to be consumed ... more Areca nut (AN) consumption is a practice of great antiquity in India and reported to be consumed by 20 to 30% of the Indian population in last 2-3 decades. Various mechanisms have been reported with reference to its adverse effects on the liver, one of which could be ingestion of aflatoxin infected AN, as aflatoxin B1 is a known hepatotoxin. Reports are available stating that the most of the ANs available in the market are substandard and contaminated with cancer- causing fungus and chewing of such poor quality, infested ANs would definitely pose severe health problems on human beings in a long time. But, to our knowledge scanty literature is available reporting the role of aflatoxin infested AN on risk of liver cancer. The evolution of such risk factors provides insight into understanding of the future burden of the disease.

Journal of Critical Reviews, 2020

Journal of Pharmaceutical Research International, 2021

Background: Basics of every aspect must be know thoroughly to JR1 with active participation durin... more Background: Basics of every aspect must be know thoroughly to JR1 with active participation during the discussion to understand any case. Active participation is must irrespective of the syllabus distributed for the PG in the syllabus as per the DCI guidelines. The cognitive knowledge, clinically for any case should not be year specific based on the syllabus, but, a collective and collaborative foundation of understanding. So to reframe the methodology of and to make the case discussion more effective, a study was planned. Study design: Cross- sectional observational Methodology: the following study will be conducted with the JR of dept of orthodontics SPDC, For comparison between the conventional and syndicate case discussion, the conventional case discussion will be entitled as Group I; while syndicate case discussion will be entitles as group II. They will be asked to present the case as per the suggested syllabus recommended by the DCI for each academic year respectively. Pre-t...

Journal of Oral and Maxillofacial Pathology, 2021

Oral submucous fibrosis (OSMF) is the morbid condition of areca nut habitual primarily affecting ... more Oral submucous fibrosis (OSMF) is the morbid condition of areca nut habitual primarily affecting the nonkeratinized oral mucosa form superficial epithelium to the basal layer. It involves any part of the oral cavity from the anterior to posterior oropharyngeal region and sometimes upper aerodigestive tract. Slowly progressive chronic inflammatory change from epithelium to underlying connective tissue causes the deposition of abnormal Introduction: Areca nut is deeply rooted sociocultural habit in India. Areca nut reported to be infested by fungi during the field and storage conditions. Areca nut alkaloids, nitrosamines, tobacco and aflatoxin are cytotoxic, immunotoxic to red blood cell and epithelial cell. Hence, the present study was conducted to assess the serum aflatoxin B 1 (AFB 1) antibody titer, percent hemolysis and transaminases in oral submucous fibrosis (OSMF) patients. Materials and Methods: In this study, 128 participants of which 88 were suffering from OSMF. Twenty participants were areca nut habitual without OSMF (habitual control) and 20 participants without any habit (healthy control). For the detection of AFB 1 antibody titer, AFB 1 antigen (Sigma) A6636 from Aspergillus flavus was used. Percent hemolysis was estimated as per the procedure described by Mathuria and Verma. Serum Glutamic oxalo acetic transaminase (SGOT) and Serum Glutamic pyruvic transaminase (SGPT) were estimated by the optimized ultraviolet method using the enzyme-linked immunosorbent assay kit. Results: Mean SGOT, SGPT, percent hemolysis and AFB 1 antibody titer were significantly higher in participants with OSMF than the habitual and healthy controls. AFB 1 antibody titer and % hemolysis in both OSMF and habitual without OSMF were showed significant correlation, i.e., increased AFB 1 antibody titer with increased % hemolysis. Conclusions: A study result demonstrates that aflatoxin causes increase in serum transaminases which is indicative of liver damage in OSMF. The combined toxic effects of areca nut alkaloids, tobacco and AFB 1 on red blood cell (RBC) cell wall might be responsible for increased percent hemolysis in OSMF and habitual control.

International Journal of Dentistry Research, 2018

Background: It is essential to search for an efficient and reliable remedy for treating oral subm... more Background: It is essential to search for an efficient and reliable remedy for treating oral submucous fibrosis taking into account the shortcomings of present treatment modalities to either provide a complete relief or treating the patients at the cost of adverse effects. Objective: Assessment of utility of Tulsi and Turmeric in treatment of oral submucous fibrosis: a clinical study. Material and methods: The study included 30 individuals. All the clinical parameters including mouth opening and burning sensation were evaluated and recorded in specially designed proforma. The burning sensation and inter-incisal distance were measured on visual analogue scale (VAS) and vernier calibre (in millimetres), respectively. The patients were instructed to apply the gel (combination of tulsi and turmeric) to the affected areas of oral cavity five times in a day. Patients were recalled after every fifteen days for continuous three months (total 6 visits for each patient). On each visit, the mouth opening and burning sensation were recorded. Results: The difference between the mouth opening before and after the treatment was found to be statistically significant. Similar significant findings were observed with reference to the reduction in burning sensation in the present study. The mean of the burning sensation before treatment was 5.43±2.02 and after treatment was 0.20±.76 as assessed by VAS. On correlation of the findings of mouth opening and burning sensation in the subjects of different grades, the results were found to statistically significant. No clinically eminent adverse reactions to the therapy were seen in any patient. Conclusion: The combination of Tulsi and Turmeric can be considered as a better alternative to the modern treatment modality in the management of all grades of OSMF..

Objective: the main objective of this study was to evaluate the prevalence of root angulation in ... more Objective: the main objective of this study was to evaluate the prevalence of root angulation in Vidarbh population using panoramic radiographs. Methods: This prospective study was carried out on Orthopantomograms of 1000 subjects between the age group ranges of 18-70 years to evaluate the prevalence of root dilacerations in Vidarbh region using orthopantomograms. Angulation of each tooth root was measured using annotation software in the CR system. A single examiner analyzed all radiographs root angulations in mesial or distal direction starting from 50° were measured. (fig 1) Results: Teeth with root angulation >50 ̊ were considered as dilacerated. In the present study maxillary and mandibular molars had the maximum number of dilacerations Conclusion:This study shows that this anomaly is distributed maximum in maxillary and mandibular posterior teeth. Additionally, the dilacerations are clearly more common in the posterior teeth which are less related to trauma than the anterio...

Multiple sclerosis (MS) is a chronic, inflammatory, demyelinating disease of the central nervous ... more Multiple sclerosis (MS) is a chronic, inflammatory, demyelinating disease of the central nervous system. The disease mostly affects young adults and is increasing in prevalence and incidence. Multiple sclerosis is characterized by periods of activity and remission which, after numerous relapses, cause permanent neurologic deficits. Diagnosis of MS is based on patient history and clinical examination supplemented by the findings of radiologic and laboratory tests. Numerous motor and sensory disturbances occur in MS and may present in the orofacial region. This medical management update highlights issues that are important to the oral health care provider, including orofacial manifestations of MS and dental considerations for patients with MS. (Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2009;108:318-327)

In dentistry, treatment modalities changed markedly when osseointegration became the basis for a ... more In dentistry, treatment modalities changed markedly when osseointegration became the basis for a predictable outcome of oral implant treatment. DVT (Digital Volume Tomography) is an effective, time saving and indispensable procedure in dental implantology which determines the available bone height at the implant sites accurately along with the osseous morphologic variations like Septae in the maxillary sinus, which cannot be demonstrated on conventional radiography. In this case MPR (multiplanar reformatting) was used for the accuracy and measurements of the ridge for pre and post implant assessment.

International Journal of Dental Clinics, 2014

Benign fibrous histiocytoma (BFH) or Dermatofibroma is a benign soft tissue tumour commonly seen ... more Benign fibrous histiocytoma (BFH) or Dermatofibroma is a benign soft tissue tumour commonly seen on the skin, but rarely occur in deep tissues. It can arise as a soft tissue mass anywhere in the human body. In deep seated lesions the diagnosis of BFH becomes difficult on the basis of clinical examination, and is frequently confirmed after local excision. An 11 year old female presented with a painless swelling on the right pre- auricular region, which was diagnosed as Benign Fibrous Histiocytoma on excisional biopsy and histopathological examination.

Mini-CEX is an assessment approach which focuses on trainees’ encounters with a variety of real p... more Mini-CEX is an assessment approach which focuses on trainees’ encounters with a variety of real patient issues, in there, routine clinical practice. 60 mini-CEX encounters were carried out involving 15 Final BDS students. They took focused history, performed clinical examination of submandibular lymph node on a patient with apical periodontitis with mandibular first molar. This was done during their clinical posting of Oral Medicine. Four assessors observed students, rated the performance, by scoring trainee on a structured form and provided an immediate feedback. Efficacy of mini-CEX method was rated on a 9-point scale. Perception of all participants and assessors regarding mini-CEX method of evaluation was taken. The mean scores of all the 15 students from 1 st to 4 th encounters given by assessors were 4.20 +_0.67, 5.20+_0.56, 7.06+_0.59 and 8.60+_0.50 respectively. The comparison of mean score of all the 15 students between 1st encounter - 2nd encounter, 1st encounter - 3rd enco...