Daniel Medina - Academia.edu (original) (raw)

Papers by Daniel Medina

Four transplantable mammary tumors, three (66, 410, and 168cl) isolated from a spontaneously occu... more Four transplantable mammary tumors, three (66, 410, and 168cl) isolated from a spontaneously occurring strain BALB/ cfCSH mammary tumor and one (D2) arising from a BALB/c hyperplastic alveolar nodule were found to grow better in mammary fatpads than at s.c. sites. Furthermore, tumor growth was better (p < 0.05) in intact mammary glands than in cleared mammary fatpads for the D2, 410, and 66 tumors (168cl was not tested). The role of immunity in these differences was investigated using the highly immunogenic 410 tumor. Tumor 410 induced equally effective immunity to subsequent chal lenge whether it was implanted s.c. or in intact fatpads. Fur thermore, in immunized animals, Tumor 410 was rejected equally well when the challenge site was intact fatpad as when s.c. Similarly, Tumor 410 induced immunity after implantation into cleared fatpads and, in immunized animals, was rejected when the challenge site was the cleared fatpad. We thus found no evidence that the mammary fatpad is immunologically priv ileged, as compared to the s.c. site, with respect to tumor transplantation antigens.

Four transplantable mammary tumors, three (66, 410, and 168cl) isolated from a spontaneously occu... more Four transplantable mammary tumors, three (66, 410, and 168cl) isolated from a spontaneously occurring strain BALB/ cfCSH mammary tumor and one (D2) arising from a BALB/c hyperplastic alveolar nodule were found to grow better in mammary fatpads than at s.c. sites. Furthermore, tumor growth was better (p < 0.05) in intact mammary glands than in cleared mammary fatpads for the D2, 410, and 66 tumors (168cl was not tested). The role of immunity in these differences was investigated using the highly immunogenic 410 tumor. Tumor 410 induced equally effective immunity to subsequent chal lenge whether it was implanted s.c. or in intact fatpads. Fur thermore, in immunized animals, Tumor 410 was rejected equally well when the challenge site was intact fatpad as when s.c. Similarly, Tumor 410 induced immunity after implantation into cleared fatpads and, in immunized animals, was rejected when the challenge site was the cleared fatpad. We thus found no evidence that the mammary fatpad is immunologically priv ileged, as compared to the s.c. site, with respect to tumor transplantation antigens.

Director: Miguel M. Delgado Data: México, 1966 Datos técnicos: Largometraje, comedia drama, 133 m... more Director: Miguel M. Delgado Data: México, 1966 Datos técnicos: Largometraje, comedia drama, 133 minutos, productora Posa Films International. S.A.

Four transplantable mammary tumors, three (66, 410, and 168cl) isolated from a spontaneously occu... more Four transplantable mammary tumors, three (66, 410, and 168cl) isolated from a spontaneously occurring strain BALB/ cfCSH mammary tumor and one (D2) arising from a BALB/c hyperplastic alveolar nodule were found to grow better in mammary fatpads than at s.c. sites. Furthermore, tumor growth was better (p < 0.05) in intact mammary glands than in cleared mammary fatpads for the D2, 410, and 66 tumors (168cl was not tested). The role of immunity in these differences was investigated using the highly immunogenic 410 tumor. Tumor 410 induced equally effective immunity to subsequent chal lenge whether it was implanted s.c. or in intact fatpads. Fur thermore, in immunized animals, Tumor 410 was rejected equally well when the challenge site was intact fatpad as when s.c. Similarly, Tumor 410 induced immunity after implantation into cleared fatpads and, in immunized animals, was rejected when the challenge site was the cleared fatpad. We thus found no evidence that the mammary fatpad is immunologically priv ileged, as compared to the s.c. site, with respect to tumor transplantation antigens.

Four transplantable mammary tumors, three (66, 410, and 168cl) isolated from a spontaneously occu... more Four transplantable mammary tumors, three (66, 410, and 168cl) isolated from a spontaneously occurring strain BALB/ cfCSH mammary tumor and one (D2) arising from a BALB/c hyperplastic alveolar nodule were found to grow better in mammary fatpads than at s.c. sites. Furthermore, tumor growth was better (p < 0.05) in intact mammary glands than in cleared mammary fatpads for the D2, 410, and 66 tumors (168cl was not tested). The role of immunity in these differences was investigated using the highly immunogenic 410 tumor. Tumor 410 induced equally effective immunity to subsequent chal lenge whether it was implanted s.c. or in intact fatpads. Fur thermore, in immunized animals, Tumor 410 was rejected equally well when the challenge site was intact fatpad as when s.c. Similarly, Tumor 410 induced immunity after implantation into cleared fatpads and, in immunized animals, was rejected when the challenge site was the cleared fatpad. We thus found no evidence that the mammary fatpad is immunologically priv ileged, as compared to the s.c. site, with respect to tumor transplantation antigens.

Director: Miguel M. Delgado Data: México, 1966 Datos técnicos: Largometraje, comedia drama, 133 m... more Director: Miguel M. Delgado Data: México, 1966 Datos técnicos: Largometraje, comedia drama, 133 minutos, productora Posa Films International. S.A.