Davor Barić - Academia.edu (original) (raw)
Papers by Davor Barić
Cardiologia Croatica, Apr 1, 2023
Introduction: Rheumatoid arthritis can cause a variety of cardiac manifestations. Pericarditis ca... more Introduction: Rheumatoid arthritis can cause a variety of cardiac manifestations. Pericarditis can be found in about 30% of the patients, however it is usually acute and asymptomatic. 1 Constrictive pericarditis is a rare complication of rheumatoid arthritis with major complications. 2 Case report: We present a case of a 70-year-old woman who presented to the emergency room with signs and symptoms of right ventricular heart failure. The patient has a 30-year-old history of seropositive rheumatoid arthritis and is currently treated with steroids and ebetrexat. Also, cardiac workup was performed a few years prior due to microvoltage in the ECG, however other than lamellar pericardial effusion with no effects on hemodynamics, no pathology was found. Initial workup showed right sided pleural effusion and cranial redistribution on chest X-ray, elevated natriuretic peptide level, as well as slightly elevated bilirubin and liver enzymes. A small amount of ascites was noted on the abdominal ultrasound. A circumferential 8-millimeter pericardial effusion, lower lateral e' wave velocity than septal e' wave velocity and a dilated vena cava were noted on the echocardiogram. Right heart catheterization showed possible signs of constriction. Treatment with non-steroid antirheumatics was initiated and prior corticosteroid therapy was escalated, however the patients' symptoms worsened, and the effusion progressed. Further magnetic resonance imaging revealed a thickened pericardium with post-contrast imbibition and septal bounce in early diastole, findings suggestive of constrictive pericarditis. Patient was referred to cardiac surgeons and radical pericardiectomy was performed with a good outcome. Conclusion: Constrictive pericarditis is a rare and easily overlooked diagnosis that should be kept in mind when assessing rheumatological patients with signs of right-sided heart failure.
Cardiologia Croatica, Apr 1, 2021
PubMed, Dec 1, 2002
Aim: To present our preliminary results with stentless aortic valve bioprostheses. Methods: From ... more Aim: To present our preliminary results with stentless aortic valve bioprostheses. Methods: From November 2001 to February 2002, 15 patients (8 men and 7 women) underwent aortic valve replacement with aortic stentless bioprosthesis. The patients age ranged from 50 to 79 years (mean+/-SD, 63.3+/-5.7 years). Three patients had aortic stenosis, 3 aortic regurgitation, and 9 combined aortic pathology. Mean+/-SD left ventricle ejection fraction was 53.0+/-13.9%. Median EuroSCORE was 4 (range, 3-10). Mean+/-SD sinotubular junction diameter measured by transesophageal echo (TEE) was 22.9+/-1.97 mm preoperatively, and the diameter of implanted prostheses was 25.9+/-2.4 mm. All valves were implanted using subcoronary technique. In 5 patients, concomitant myocardial revascularization was performed. Results: Mean+/-SD total bypass time was 126.7+/-45.9 min (range, 96-180) and cross-clamp time was 88.7+/-15.6 min (range, 69-118). There were no in-hospital deaths or neurological complications. All patients were discharged with only antiagregation agents in therapy. TEE control was performed 1 week after the surgery. The mean systolic gradient across the prosthesis was 25.6+/-5.6 mm Hg and maximum 25.9+/-7.3 mm Hg. No aortic insufficiency was observed in 6 and only minor in 9 patients in postoperative TEE. Conclusion: Although the implantation of aortic stentless bioprosthesis is technically challenging and time-consuming, early postoperative hemodynamic results are satisfactory.
European Journal of Cardio-Thoracic Surgery, Aug 1, 2002
Objective: Acute dissection of the ascending aorta requires immediate surgical intervention. In t... more Objective: Acute dissection of the ascending aorta requires immediate surgical intervention. In this study, we report our first results with valve sparing aortic root reconstruction removing all the diseased tissues. Methods: From August 1995 to December 2000, 22 patients with acute aortic dissection of the ascending aorta (Stanford type A) underwent valve sparing aortic root reconstruction. Their ages ranged from 20 to 76 years (52^15, 68% males). Dissection was found in the ascending aorta (3 patients) or both in the ascending aorta and aortic arch (19 patients; 86%). Course and length of hospitalization, echocardiographic and clinical follow-up, complications and mortality were analysed. Results: Mean cardiopulmonary bypass time was 212^56 min (134-352 min), mean aortic cross clamp time was 157^24 min (114-205 min). In patients undergoing additional arch replacement (n ¼ 19), circulatory arrest was 35^18 min (11-75 min). After reconstruction, intraoperative echocardiography showed aortic insufficiency (AI) grade 0 in 16 patients (84%) and grade 1 in three patients (16%). Stay in intensive care unit was 2.1^0.7 days, and postoperative hospitalization was 21^14.4 days. There were three perioperative deaths (14%). Mean post-operative follow-up was 18.4^18 months (0.4-65.4 month). One patient died 10 months postoperatively. At follow-up, no patient suffered AI grade 2 or higher, and no reoperation for aortic valve failure was necessary. All patients presented with a favorable exercise tolerance being in New York Heart Association functional class I or II. Conclusion: Valve sparing aortic root reconstruction in patients with type A dissection can be performed with acceptable intraoperative mortality and morbidity and excellent results during followup. The complete resection of the diseased aorta is particularly appealing.
Croatian Medical Journal, Dec 1, 2014
Knjiga sažetaka, Nov 14, 2006
Objective: We sought to compare the early clinical outcome of two surgical approaches for off-pum... more Objective: We sought to compare the early clinical outcome of two surgical approaches for off-pump total arterial revascularization. Methods: From 2/1998 to 12/2004, 279 patients underwent off-pump total arterial revascularization utilizing both IMA's and radial arteries. ...
Background: The use of arterial grafts in coronary surgery offers many advantages, but most of th... more Background: The use of arterial grafts in coronary surgery offers many advantages, but most of them are still to be proven in long-term results. We present our 8-year experience of myocardial revascularization with arterial grafts. // Methods: From february 1998 to January 2006 540 patients (511 men and 29 women) underwent coronary revascularization with multiple arterial grafts using internal mammary and radial arteries. Off-pump revascularizytion was performed in 330 patients (61, 1%). The mean age was 58 +/- 7 years, mena LVEF 57% +/- 11% and mean EuroSCORE 2, 2 +/- 1, 9. We reviewed perioperative and postoperative data and in hospital mortality. // Results: The left internal mammary artery was used as a graft in 475 patients (88%), the right internal mammary artery was used in 13 patietns (2, 4%), and the radial artery was used in 519 patients (96, 1%). No venous grafts were used. A total of 1350 distal anastomosis were created, an average of 2, 5 per patient. We performed 131 patient (24, 3%) with no touch technique. There were 12 reoperatings (2, 2%), mjost of them because of mediastinal bleeding. Thirteen patients (2, 4%) experienced perioperative myocardial infarction. Fourteen patients (2, 6%) died in the hospital within 30 days of operation. // Conclusion: Our experience shows that arterial myocardial revascularization can be safely performed for treatment of multiple-vessel coronary disease. The long term benefit for patients is to evaluated in the future.
Cardiologia Croatica, Nov 1, 2022
Cardiologia Croatica, 2021
European Journal of Cardio-Thoracic Surgery, Oct 1, 2007
Cardiologia Croatica, Nov 1, 2016
Therapeutics and Clinical Risk Management, Nov 1, 2017
Texas Heart Institute Journal, Apr 1, 2017
Cardiologia Croatica, Apr 1, 2021
Aim: To report a case of a patient with undiagnosed endocarditis that presented as COVID-19 pneum... more Aim: To report a case of a patient with undiagnosed endocarditis that presented as COVID-19 pneumonia. Case report: 62-year-old woman with a history of arterial hypertension, presented to the Emergency Department of General Hospital Koprivnica with fever and cough lasting for 7 days and general fatigue lasting for 3 weeks. Her vital signs were in physiologic range, while auscultatory she had a systolic murmur over the whole precordium with diffuse pulmonary crackles. Chest radiograph showed bilateral interstitial pneumonia whilst laboratory results displayed elevated inflammatory markers, cardiac troponin and D-dimers combined with mild partial respiratory insufficiency. She was admitted to an isolated COVID-19 ward where empiric antibiotic therapy with ceftriaxone began in parallel with dexamethasone, dalteparin and oxygen therapy via nasal cannula. During the night of admission, she became hemodynamically unstable and fluid resuscitation in conjunction with inotropes was initiated. Emergency pulmonary CT angiography ruled out pulmonary embolism and showed bilateral ground-glass changes with pleural effusion as well as signs of venous congestion. Subsequently, COV-ID-19 was confirmed with the RT-PCR test. After a 10-day isolation period, she was transferred to the Cardiology Department where transthoracic echocardiography was performed. Massive vegetation on the anterior mitral leaflet that caused obstruction of the left ventricular outflow tract and moderate mitral regurgitation with filiform vegetation on the aortic valve were shown. Initial antibiotic therapy was swapped to amikacin and gentamicin. Further hospital stay was complicated with paroxysmal atrial fibrillation, worsening of heart failure and psychological disturbance. Indication for emergency valve replacement and transfer to the University Hospital Dubrava was indicated. Intraoperatively, massive vegetation on A1/A2 section of mitral leaflet and a smaller vegetation on ventricular side of left and noncoronary cusps of the aortic valve were visible. Both valves were replaced with mechanical valves with satisfying results and the patient was returned to the parent hospital. Coagulase-negative S. aureus susceptible to vancomycin was later verified on the mitral leaflet specimen. Conclusion: Despite our focus on SARS-CoV-2 pandemic, it is important not to neglect other diagnosis and usefulness of echocardiography as a powerful diagnostic tool in everyday clinical practice.
5TI 'stInsal l.rot:ejsnus puE s>lsrr 1ecr8-rns alqerdacce qrr-,t,r ,t3o1oq1ed cn-ror ;o sestc xel... more 5TI 'stInsal l.rot:ejsnus puE s>lsrr 1ecr8-rns alqerdacce qrr-,t,r ,t3o1oq1ed cn-ror ;o sestc xelduroJ j:o lueruteeJl JoJ elrleurell€ poo8 r sr ell^-E r{tr-,lr {unrt ruegdala patuets oqJ :uorsnlruoJ '.{\olloJ u.ral Suoi Sur-rnp perp sluetled o-t\t pu€%6 Jo trr]Ier:our a^Beredouad e sluase;d rlrl-,!\ IIOI er{t ur perp tuertsd ouo 'esorll jo o,nl ur pe^losar Pue '(% LZ) stuarted aerqt ur pe^rasqo se,tt alreu luerrnrer arll Jo a8rruup osle 'suoErcriduoc u.rel uorls qlr-{\ ouo pur 'suonecrldruoc u;al Suol qrl-e\ L\l peg ruerred auo 'uonJa3ur puno..\\ IEuJets JoJ poteJodoal sE,tt luer]rd au6; 'tge.r8 ar{t j:o uorsnlrro ot enp ,{.rel.re uBr^EIrqns Ual Jo VEJ ptrl osl" oq.{\ Jo euo '8urpea1q ot enp uorsr^er tue.{\repun (799) sluerred rnog '9t o1 lZ tuo.r3 su.r e8urr eqr q8noqrp ty7 azrs l.+ErB pesn .{psour e1t '(O"gZ-3.gI) Jo-cZ sE-{\ duel Sutloor uErpew 'lserlE ,{;otrlncJrc Jo (SZZ
6II 'uollJury puc uoE€.reue8er :e1nor:1uaa 4a1 aqt Jo tueruoru€que lerrpeu .rog locolo.rd erlt pu... more 6II 'uollJury puc uoE€.reue8er :e1nor:1uaa 4a1 aqt Jo tueruoru€que lerrpeu .rog locolo.rd erlt pue enbruqcel 1uci8:ns 'ssaoo.rd uoBrelas arp luese.rd 11r,tr e,tr t.rodeJ srql uI 'Surpueq .,Lrat:e l-reuoulnd olgls:a,re.r qlr..\r uortetueldsue;r treeq e roJ parro;er uerplrllr Suno,{1o dno.r8 percales i1-redo.rd
Cardiologia Croatica, Apr 1, 2019
Cardiologia Croatica, Apr 1, 2023
Introduction: Rheumatoid arthritis can cause a variety of cardiac manifestations. Pericarditis ca... more Introduction: Rheumatoid arthritis can cause a variety of cardiac manifestations. Pericarditis can be found in about 30% of the patients, however it is usually acute and asymptomatic. 1 Constrictive pericarditis is a rare complication of rheumatoid arthritis with major complications. 2 Case report: We present a case of a 70-year-old woman who presented to the emergency room with signs and symptoms of right ventricular heart failure. The patient has a 30-year-old history of seropositive rheumatoid arthritis and is currently treated with steroids and ebetrexat. Also, cardiac workup was performed a few years prior due to microvoltage in the ECG, however other than lamellar pericardial effusion with no effects on hemodynamics, no pathology was found. Initial workup showed right sided pleural effusion and cranial redistribution on chest X-ray, elevated natriuretic peptide level, as well as slightly elevated bilirubin and liver enzymes. A small amount of ascites was noted on the abdominal ultrasound. A circumferential 8-millimeter pericardial effusion, lower lateral e' wave velocity than septal e' wave velocity and a dilated vena cava were noted on the echocardiogram. Right heart catheterization showed possible signs of constriction. Treatment with non-steroid antirheumatics was initiated and prior corticosteroid therapy was escalated, however the patients' symptoms worsened, and the effusion progressed. Further magnetic resonance imaging revealed a thickened pericardium with post-contrast imbibition and septal bounce in early diastole, findings suggestive of constrictive pericarditis. Patient was referred to cardiac surgeons and radical pericardiectomy was performed with a good outcome. Conclusion: Constrictive pericarditis is a rare and easily overlooked diagnosis that should be kept in mind when assessing rheumatological patients with signs of right-sided heart failure.
Cardiologia Croatica, Apr 1, 2021
PubMed, Dec 1, 2002
Aim: To present our preliminary results with stentless aortic valve bioprostheses. Methods: From ... more Aim: To present our preliminary results with stentless aortic valve bioprostheses. Methods: From November 2001 to February 2002, 15 patients (8 men and 7 women) underwent aortic valve replacement with aortic stentless bioprosthesis. The patients age ranged from 50 to 79 years (mean+/-SD, 63.3+/-5.7 years). Three patients had aortic stenosis, 3 aortic regurgitation, and 9 combined aortic pathology. Mean+/-SD left ventricle ejection fraction was 53.0+/-13.9%. Median EuroSCORE was 4 (range, 3-10). Mean+/-SD sinotubular junction diameter measured by transesophageal echo (TEE) was 22.9+/-1.97 mm preoperatively, and the diameter of implanted prostheses was 25.9+/-2.4 mm. All valves were implanted using subcoronary technique. In 5 patients, concomitant myocardial revascularization was performed. Results: Mean+/-SD total bypass time was 126.7+/-45.9 min (range, 96-180) and cross-clamp time was 88.7+/-15.6 min (range, 69-118). There were no in-hospital deaths or neurological complications. All patients were discharged with only antiagregation agents in therapy. TEE control was performed 1 week after the surgery. The mean systolic gradient across the prosthesis was 25.6+/-5.6 mm Hg and maximum 25.9+/-7.3 mm Hg. No aortic insufficiency was observed in 6 and only minor in 9 patients in postoperative TEE. Conclusion: Although the implantation of aortic stentless bioprosthesis is technically challenging and time-consuming, early postoperative hemodynamic results are satisfactory.
European Journal of Cardio-Thoracic Surgery, Aug 1, 2002
Objective: Acute dissection of the ascending aorta requires immediate surgical intervention. In t... more Objective: Acute dissection of the ascending aorta requires immediate surgical intervention. In this study, we report our first results with valve sparing aortic root reconstruction removing all the diseased tissues. Methods: From August 1995 to December 2000, 22 patients with acute aortic dissection of the ascending aorta (Stanford type A) underwent valve sparing aortic root reconstruction. Their ages ranged from 20 to 76 years (52^15, 68% males). Dissection was found in the ascending aorta (3 patients) or both in the ascending aorta and aortic arch (19 patients; 86%). Course and length of hospitalization, echocardiographic and clinical follow-up, complications and mortality were analysed. Results: Mean cardiopulmonary bypass time was 212^56 min (134-352 min), mean aortic cross clamp time was 157^24 min (114-205 min). In patients undergoing additional arch replacement (n ¼ 19), circulatory arrest was 35^18 min (11-75 min). After reconstruction, intraoperative echocardiography showed aortic insufficiency (AI) grade 0 in 16 patients (84%) and grade 1 in three patients (16%). Stay in intensive care unit was 2.1^0.7 days, and postoperative hospitalization was 21^14.4 days. There were three perioperative deaths (14%). Mean post-operative follow-up was 18.4^18 months (0.4-65.4 month). One patient died 10 months postoperatively. At follow-up, no patient suffered AI grade 2 or higher, and no reoperation for aortic valve failure was necessary. All patients presented with a favorable exercise tolerance being in New York Heart Association functional class I or II. Conclusion: Valve sparing aortic root reconstruction in patients with type A dissection can be performed with acceptable intraoperative mortality and morbidity and excellent results during followup. The complete resection of the diseased aorta is particularly appealing.
Croatian Medical Journal, Dec 1, 2014
Knjiga sažetaka, Nov 14, 2006
Objective: We sought to compare the early clinical outcome of two surgical approaches for off-pum... more Objective: We sought to compare the early clinical outcome of two surgical approaches for off-pump total arterial revascularization. Methods: From 2/1998 to 12/2004, 279 patients underwent off-pump total arterial revascularization utilizing both IMA's and radial arteries. ...
Background: The use of arterial grafts in coronary surgery offers many advantages, but most of th... more Background: The use of arterial grafts in coronary surgery offers many advantages, but most of them are still to be proven in long-term results. We present our 8-year experience of myocardial revascularization with arterial grafts. // Methods: From february 1998 to January 2006 540 patients (511 men and 29 women) underwent coronary revascularization with multiple arterial grafts using internal mammary and radial arteries. Off-pump revascularizytion was performed in 330 patients (61, 1%). The mean age was 58 +/- 7 years, mena LVEF 57% +/- 11% and mean EuroSCORE 2, 2 +/- 1, 9. We reviewed perioperative and postoperative data and in hospital mortality. // Results: The left internal mammary artery was used as a graft in 475 patients (88%), the right internal mammary artery was used in 13 patietns (2, 4%), and the radial artery was used in 519 patients (96, 1%). No venous grafts were used. A total of 1350 distal anastomosis were created, an average of 2, 5 per patient. We performed 131 patient (24, 3%) with no touch technique. There were 12 reoperatings (2, 2%), mjost of them because of mediastinal bleeding. Thirteen patients (2, 4%) experienced perioperative myocardial infarction. Fourteen patients (2, 6%) died in the hospital within 30 days of operation. // Conclusion: Our experience shows that arterial myocardial revascularization can be safely performed for treatment of multiple-vessel coronary disease. The long term benefit for patients is to evaluated in the future.
Cardiologia Croatica, Nov 1, 2022
Cardiologia Croatica, 2021
European Journal of Cardio-Thoracic Surgery, Oct 1, 2007
Cardiologia Croatica, Nov 1, 2016
Therapeutics and Clinical Risk Management, Nov 1, 2017
Texas Heart Institute Journal, Apr 1, 2017
Cardiologia Croatica, Apr 1, 2021
Aim: To report a case of a patient with undiagnosed endocarditis that presented as COVID-19 pneum... more Aim: To report a case of a patient with undiagnosed endocarditis that presented as COVID-19 pneumonia. Case report: 62-year-old woman with a history of arterial hypertension, presented to the Emergency Department of General Hospital Koprivnica with fever and cough lasting for 7 days and general fatigue lasting for 3 weeks. Her vital signs were in physiologic range, while auscultatory she had a systolic murmur over the whole precordium with diffuse pulmonary crackles. Chest radiograph showed bilateral interstitial pneumonia whilst laboratory results displayed elevated inflammatory markers, cardiac troponin and D-dimers combined with mild partial respiratory insufficiency. She was admitted to an isolated COVID-19 ward where empiric antibiotic therapy with ceftriaxone began in parallel with dexamethasone, dalteparin and oxygen therapy via nasal cannula. During the night of admission, she became hemodynamically unstable and fluid resuscitation in conjunction with inotropes was initiated. Emergency pulmonary CT angiography ruled out pulmonary embolism and showed bilateral ground-glass changes with pleural effusion as well as signs of venous congestion. Subsequently, COV-ID-19 was confirmed with the RT-PCR test. After a 10-day isolation period, she was transferred to the Cardiology Department where transthoracic echocardiography was performed. Massive vegetation on the anterior mitral leaflet that caused obstruction of the left ventricular outflow tract and moderate mitral regurgitation with filiform vegetation on the aortic valve were shown. Initial antibiotic therapy was swapped to amikacin and gentamicin. Further hospital stay was complicated with paroxysmal atrial fibrillation, worsening of heart failure and psychological disturbance. Indication for emergency valve replacement and transfer to the University Hospital Dubrava was indicated. Intraoperatively, massive vegetation on A1/A2 section of mitral leaflet and a smaller vegetation on ventricular side of left and noncoronary cusps of the aortic valve were visible. Both valves were replaced with mechanical valves with satisfying results and the patient was returned to the parent hospital. Coagulase-negative S. aureus susceptible to vancomycin was later verified on the mitral leaflet specimen. Conclusion: Despite our focus on SARS-CoV-2 pandemic, it is important not to neglect other diagnosis and usefulness of echocardiography as a powerful diagnostic tool in everyday clinical practice.
5TI 'stInsal l.rot:ejsnus puE s>lsrr 1ecr8-rns alqerdacce qrr-,t,r ,t3o1oq1ed cn-ror ;o sestc xel... more 5TI 'stInsal l.rot:ejsnus puE s>lsrr 1ecr8-rns alqerdacce qrr-,t,r ,t3o1oq1ed cn-ror ;o sestc xelduroJ j:o lueruteeJl JoJ elrleurell€ poo8 r sr ell^-E r{tr-,lr {unrt ruegdala patuets oqJ :uorsnlruoJ '.{\olloJ u.ral Suoi Sur-rnp perp sluetled o-t\t pu€%6 Jo trr]Ier:our a^Beredouad e sluase;d rlrl-,!\ IIOI er{t ur perp tuertsd ouo 'esorll jo o,nl ur pe^losar Pue '(% LZ) stuarted aerqt ur pe^rasqo se,tt alreu luerrnrer arll Jo a8rruup osle 'suoErcriduoc u.rel uorls qlr-{\ ouo pur 'suonecrldruoc u;al Suol qrl-e\ L\l peg ruerred auo 'uonJa3ur puno..\\ IEuJets JoJ poteJodoal sE,tt luer]rd au6; 'tge.r8 ar{t j:o uorsnlrro ot enp ,{.rel.re uBr^EIrqns Ual Jo VEJ ptrl osl" oq.{\ Jo euo '8urpea1q ot enp uorsr^er tue.{\repun (799) sluerred rnog '9t o1 lZ tuo.r3 su.r e8urr eqr q8noqrp ty7 azrs l.+ErB pesn .{psour e1t '(O"gZ-3.gI) Jo-cZ sE-{\ duel Sutloor uErpew 'lserlE ,{;otrlncJrc Jo (SZZ
6II 'uollJury puc uoE€.reue8er :e1nor:1uaa 4a1 aqt Jo tueruoru€que lerrpeu .rog locolo.rd erlt pu... more 6II 'uollJury puc uoE€.reue8er :e1nor:1uaa 4a1 aqt Jo tueruoru€que lerrpeu .rog locolo.rd erlt pue enbruqcel 1uci8:ns 'ssaoo.rd uoBrelas arp luese.rd 11r,tr e,tr t.rodeJ srql uI 'Surpueq .,Lrat:e l-reuoulnd olgls:a,re.r qlr..\r uortetueldsue;r treeq e roJ parro;er uerplrllr Suno,{1o dno.r8 percales i1-redo.rd
Cardiologia Croatica, Apr 1, 2019