Davut Baltaci - Academia.edu (original) (raw)

Papers by Davut Baltaci

Nigerian Journal of Clinical Practice, 2017

Objective: Obesity is a major public health problem and great risk for not only cardiovascular di... more Objective: Obesity is a major public health problem and great risk for not only cardiovascular diseases but also cancer, musculoskeletal, and gynecological diseases. This study was aimed to investigate the association between serum Vitamin B12 (vitB12), body mass index (BMI), and nutritional status among obese women. Methods: This cross-sectional study enrolled consecutive female subjects. The consumptions of red meat, fish, bovine liver, egg, and mushroom were recorded. According to the Dietary Reference Intakes, the patients were categorized as insufficiency and sufficiency. Three cutoff points were defined for vitB12 status: (1) Deficiency if vitB12 is <200 pg/mL; (2) insufficiency if vitB12 is 250-350 pg/mL, and (3) sufficient if vitB12 is ≥350 pg/mL. According to BMI, the patients were assigned to nonobese and obese groups. BMI, serum vitB12 level, consumptions of red meat, fish, bovine liver, egg, and mushroom were evaluated and compared between two groups. Results: Mean level of vitB12 was 247.8 ± 10.4 pg/mL and significantly associated with consumption of egg (P = 0.031), bovine liver (P = 0.004), mushroom (P = 0.040), and red meat (P = 0.003). VitB12 was significantly higher in nonobese than obese group (282.5 ± 106.8 vs. 242.5 ± 107.5 pg/mL, P = 0.001). The ratio of vitB12 deficiency was significantly higher in obese than nonobese group (37.6% vs. 24.7%; P = 0.019). VitB12 level was negatively correlated with BMI (r = −0.155; P < 0.001), but not insulin resistance (r = −0.172; P = 0.062). Conclusion: Obesity was associated with low level of vitB12 in obese women, and more likely to be vitB12 deficient. Consumption of certain types of food contributes to increase vitB12 level.

Acta Cardiologica Sinica, 2017

The aim of our study was to evaluate in stable outpatients with systolic heart failure (HF) the 3... more The aim of our study was to evaluate in stable outpatients with systolic heart failure (HF) the 3 months effect of ivabradine on LV synchronization and Tei index in stable outpatients with systolic HF. We evaluated prospectively 40 (30 males, 10 females) patients with HF. All patients were evaluated before and after treatment by transthoracic M mode, two dimensional (2D), pulsed-wave (PW), continuous wave (CW), color flow and tissue Doppler imaging (TDI) and tissue synchronization imaging (TSI). Standard deviation of Ts of the 12 LV segments (Ts-SD-12) is the most widely used parameter of intra-LV asynchrony. Thirty men and 10 women with mean ± SD age of 64.7 ± 9.9 years were included in this study. Most of the patients benefitted from some degree of clinical improvement, 12/16 (75.0%) from NYHA III to II and 18/24 (75.0%) from II to I, respectively. Resting heart rate was significantly reduced after ivabradine treatment (84.3 ± 11.4 vs. 66.5 ± 11.5 bpm, p < 0.001). E/E' and ...

JPMA. The Journal of the Pakistan Medical Association, Dec 1, 2016

To investigate physicians' smoking cessation practice, consultation for smoking intervention ... more To investigate physicians' smoking cessation practice, consultation for smoking intervention for hospitalised patients and its determinants. The cross-sectional study was conducted at Duzce University Hospital, Duzce, Turkey, from January to April 2013, and comprised hospitalised patients. The survey, including smoking habits and 5As (Ask, Advise, Assess, Assist and Arrange) steps of smoking intervention practiced by physicians was applied to those patients discharged from the hospital. SPSS 20 was used for statistical analysis.. Of the 502(31.6%) participants, 264(52.6%) were women and 238(47.4%) were men. The overall mean age was 52.8±18.2 years. Besides, 269(53.6%) respondents were at the level of elementary school education; 289(57.6%) had chronic disease; 119(23.7%) were current and 106(21.1%) were former smokers. The frequency of current smokers among men with chronic disease was significantly lower compared to those who did not have chronic disease (p=0.017). In women, th...

Turkiye Klinikleri Journal of Family Medicine Special Topics, 2012

Journal of the College of Physicians and Surgeons Pakistan Jcpsp, May 1, 2014

A 28-year-old man was admitted to the emergency department with lumbar pain owing to a motorbike ... more A 28-year-old man was admitted to the emergency department with lumbar pain owing to a motorbike accident. On clinical examination, abdominal tenderness, pelvic and left cruris pains were present. Erythrocytes, leucocytes and protein was found to be positive in urine analysis. Abdominal computed tomography with intravenous contrast solution showed contrast enhancement in 80% of right kidney, and 30% of left kidney; some intra-abdominal free fluid was also seen. Conservative management was planned for bilateral renal infarction. Urine output was 1.1 L per day. He was discharged on the seventh day of the hospital stay. The patient had not got any problems on the sixth month follow-up. Urine output is a very important parameter for multiple trauma patients. Any decrease in urine output may not be seen inspite of the presence of bilateral renal damage as in the case of the patient, and this situation does not allow ruling out renal injury completely. Hence, emergency physician should still be careful about the risk of renal injury.

European Respiratory Journal, Sep 1, 2013

Turkish Journal of Medical Sciences, Aug 14, 2012

To investigate the correlation between vitamin B12 and body mass index (BMI) along with insulin r... more To investigate the correlation between vitamin B12 and body mass index (BMI) along with insulin resistance (IR) in middle-aged obese women. Materials and methods: Th e study was designed as a case-control study. Th e study group included middle-aged obese women and the control group included aged-matched lean women. Weight, height, and hip and waist circumferences were measured. Biochemical parameters such as fasting and postprandial glucose, vitamin B12 and folic acid levels, and lipid profi les were assayed. Results: Enrolled in the study were 116 middle-aged obese and 103 aged-matched healthy lean women. Th e vitamin B12 level of the obese women was signifi cantly lower than that of the lean women (244.1 ± 131.5 pg/mL vs. 336.2 ± 163.1 pg/mL, P = 0.002). However, there was no signifi cant diff erence in folic acid levels between the groups (P > 0.05). Th e vitamin B12 level was similar in the obese women with metabolic syndrome and those without (245.1 ± 145.3 pg/mL vs. 241.2 ± 96.5 pg/mL, P > 0.05), but the level in the control group was signifi cantly higher than that of patients with obesity and metabolic syndrome (P = 0.010 and P = 0.020, respectively). Vitamin B12 levels correlated with BMI (r =-0.259, P = 0.003) but not with IR (r =-0.053, P > 0.05). Conclusion: Th e vitamin B12 concentration was low in obese patients and this level negatively correlated with BMI, but not with homeostasis model assessment-estimated IR (HOMA-IR).

Turkiye Klinikleri Journal of Neurology, 2012

Mad honey intoxication is a rare food poisoning which has been known since a long time. Gastroint... more Mad honey intoxication is a rare food poisoning which has been known since a long time. Gastrointestinal, cardiovascular, pulmonary and neurological symptoms are well known symptoms in mad-honey intoxication. Hypnic headache is a rare form of primary headaches. It is usually seen in older people and occurs during night sleeping. Its pathogenesis is not exactly known. Herein, we present a case of mad-honey intoxication mimicking hypnic headache due to ingestion of mad-honey, which has been commonly used for healing among people living Black Sea region. The patient was admitted to our clinic with throbbing headache during night sleeping. It was diagnosed with hypnic headache, based on her anamnesis, neurological examination, and laboratory findings. The patient implied that her headache had occurred whenever she ingested some amount of mad-honey before sleeping, disappeared with its cessation and reoccurred with its ingestion, so we considered that headache was induced by intake of mad-honey. In this report, we aimed to highlight the importance of history taking about traditional foods triggering headache during consultation with patient.

Konuralp Tıp Dergisi, 2015

Bu çalışmada, Düzce Üniversitesi Tıp Fakültesi'ndeki araştırma görevlilerinde, iş doyumu düzeyi i... more Bu çalışmada, Düzce Üniversitesi Tıp Fakültesi'ndeki araştırma görevlilerinde, iş doyumu düzeyi ile depresyon derecesi, kişisel ve çevresel faktörler arasındaki ilişkilerin değerlendirilmesi amaçlanmıştır. Yöntem: Bu tanımlayıcı ve kesitsel çalışmaya, 70'i (%60) erkek, 47'si (%40) kadın 26-34 yaş aralığında 117 araştırma görevlisi katıldı. Yüz yüze görüşme yöntemiyle yapılan yarı yapılandırılmış anket formunda açık uçlu sorular ile iki veya daha fazla seçenekli sorular yer almaktaydı. Anket formu demografik özellikler, antidepresan ilaç kullanımı, kronik hastalık durumu, çalışma koşulları, alışkanlıklar ve boş zaman uğraşısı ile ilgili sorular içermekteydi. Araştırmada yarı yapılandırılmış anket formuna Beck Depresyon Envanteri, Minnesota İş Doyum Ölçeği de eklenmiştir. Bulgular: Çalışmamızda Uzmanlık eğitiminin zorluğu, insan fizyolojisini zorlayan iş yükü, yoğun çalışma temposu, hekim kimliğine saygının önceki dönemlere nazaran azalması ve tabiî ki ücretteki yetersizlik gibi nedenlerle asistan hekimlerin çoğu (n=74 kişi; %63,2) imkânı olduğu takdirde farklı bir fakülte (farklı bir meslek dalı) tercihi yapabileceklerini belirtmiştir. Çalışma ortamındaki fiziki yetersizlikler, yardımcı personel azlığı, nöbet sayılarının fazlalığı, nöbette kalan asistan sayısında yetersizlik ve en önemlisi nöbet sonrası izinden mahrumiyet asistanların genel, iç ve dışsal iş doyumlarında azalmaya neden olmaktadır. Sonuç: Araştırma görevlilerinin imkânı olduğu takdirde mevcut bölümünden daha az iş yükünün ve risk faktörünün olduğu alanları tercih etme düşüncesinde olduğu belirlenmiştir. Farklı uzmanlık dallarındaki hekimlerin içsel, dışsal ve genel iş doyum puan ortalamaları arasında anlamlı bir fark bulunamamıştır.

Clinical and Experimental Hypertension, 2010

The Seventh Report of the Joint National Committee on the Prevention, Detection, Evaluation, and ... more The Seventh Report of the Joint National Committee on the Prevention, Detection, Evaluation, and Treatment of High Blood Pressure classifies blood pressure (BP) as normal, prehypertension, and hypertension. Although it has been shown that there is a relationship between hypertension and arterial stiffness, there is not sufficient data about arterial stiffness in patients with prehypertension. The present study was designed to evaluate arterial stiffness and wave reflections in subjects with prehypertension. We evaluated arterial stiffness and wave reflections of 45 subjects with prehypertension and an age-matched control group of 40 normotensive individuals, using applanation tonometry (Sphygmocor, AtCor Medical, Sydney, Australia). Aortic pulse wave velocity (PWV) was measured as indices of elastic-type aortic stiffness. The heart rate-corrected augmentation index (AIx@75) was estimated as a composite marker of wave reflections and arterial stiffness. Aortic PWV (10 +/- 2.5 vs. 8.6 +/- 1.7, m/s, p = 0.004) and AIx@75 (21 +/- 8.3 vs. 10 +/- 9.1, %, p = 0.0001) were significantly higher in subjects with prehypertension than in the control group. In multiple linear regression analysis, we found that the presence of the prehypertension was a significant predictor of aortic PWV (beta = 0.26, p = 0.009) and AIx@75 (beta = 0.46, p = 0.0001). Our results suggest that arterial functions were impaired even at the prehypertensive stage.

International journal of clinical and experimental medicine, 2015

Metabolic syndrome is a cluster of disorders and great risk for cardiovascular diseases. We aimed... more Metabolic syndrome is a cluster of disorders and great risk for cardiovascular diseases. We aimed to investigate association between severity of metabolic syndrome (MetS) and anthropometric measurements, and to evaluate correlation of MetS and its components with metabolic deterioration and inflammatory indexes. The cross-sectional study enrolled 1474 patients with obesity and overweight. The patients were grouped as MetS and Non-MetS, and were sub-grouped as group 1 (three criteria), 2 (four criteria) and 3 (≥ five criteria) according to NCEP ATP III. Mean age was 38.7 ± 11.9 years and BMI was 35.1 ± 6.3 kg/m(2). Lipid profile, anthropometric and blood pressure measurements, liver function tests, bioelectric impedance body fat compositions, insulin resistance and HbA1c, and spot urinary albumin-creatinine ratio were significantly different between groups of MetS and Non-MetS. Age, lipid profile, bioelectric impedance fat analyses, BMI, blood pressure values, glucose, insulin resist...

Tobacco Induced Diseases, 2015

Background: Primary care providers are uniquely positioned to initiate smoking cessation. We aime... more Background: Primary care providers are uniquely positioned to initiate smoking cessation. We aimed to evaluate knowledge levels about the health effects of smoking and attitudes toward smoking and tobacco control activities among primary care providers. Methods: In the cross-sectional and primary care-based study, self-administered surveys modified from the WHO Global Health Professional Survey 5A steps of smoking cessation practice (Ask, Advise, Assess, Assist and Arrange) were provided to primary care physicians (PCPhs) and nurses (PCNs). Results: Respondents included 1182 PCPhs and 1063 PCNs. The proportions of current and former smokers were significantly higher among PCPhs than among PCNs (34.4 vs. 30.7 % and 14.0 vs. 10.1 %, respectively; both P < 0.001). We observed that 77.2 % of PCPhs and 58.4 % of PCNs always or rarely practiced an "Ask" step about their patients' smoking status (P < 0.001). One-third of PCPhs (33.8 %) stated that they always practiced an "Ask" step, whereas only 27.6 % of PCNs always did so in their practice (P < 0.001). A small minority of primary care providers had advised patients to quit smoking, although there was a significant difference in this between PCNs and PCPhs (8.4 vs. 15.6 %; P < 0.001). Most PCPhs considered themselves competent in advising about smoking interventions, but only a minority of PCNs did so (75.1 vs. 17.3 %; P < 0.001). Among barriers to tobacco intervention measures, lack of time was the item most commonly cited by PCPhs, whereas low patient priority was most commonly cited by PCNs (35.9 and 35.7 %; P < 0.001). Conclusions: Smoking intervention practice by primary care nurses was quite low. Lack of time and low patient priority were identified as barriers by primary care providers. Strategies by which primary care providers could improve tobacco control should be established.

European Respiratory Journal, 2015

Smoking is main problem among family physicians. They are gate keeper and role model for their pa... more Smoking is main problem among family physicians. They are gate keeper and role model for their patients. Aim: To evaluate the prevalence of smoking among Turkish family physicians and smoking cessation training. Methods: The cross-sectional and primary care based study was has been conducted since May 2014 and will be completed in May 2015. The primary care-based survey was applied in face to face interview to family physicians. Results: The study enrolled 261 physicians (mean age of 46 years-old). Male to female ratio was 95/166. The frequency of current smokers was 29.1%. The ratio of current smokers among male to female physicians was significantly high (37.3% versus 14.7%; p Conclusion: The preliminary study revealed that the smoking prevalence was quite high and comparatively higher among male than female. The significant difference was more marked under age of 50. Pre-and post-graduate training on smoking cessation among family physicians seemed to be not satisfactory.

Asian Pacific journal of cancer prevention: APJCP

Background: Colon cancer is one of the most common cancer worldwide. Apoptosis, is a necessary ph... more Background: Colon cancer is one of the most common cancer worldwide. Apoptosis, is a necessary physiological process for cell elimination which is very important both cellular homeostasis and cell proliferation and differantiation. This also leads to uncontrolled cell growth and tumor development. Survivin, a member of the IAP family, plays a key role in promotion of cell proliferation as well as inhibition of apoptosis in cancer cells. The aim of this study was to investigate whether specific genetic polymorphisms of Survivin could be associated with colon cancer development and progression in a Turkish population. Our study is the first to our knowledge to investigate the relationship between colon cancer risk and Survivin gene polymorphisms. Methods: The relation between colon cancer and survivin -31 G/C (rs9904341), -241 C/T (rs17878467) and -625 C/G (rs8073069) polymorphism in promotor site of survivin gene associated with apoptosis was investigated by using polymerase chain re...

International Journal of Statistics in Medical Research, 2013

SVMs were initially developed to perform binary classification. However, in many real-world probl... more SVMs were initially developed to perform binary classification. However, in many real-world problems, particularly pattern recocnation studies, aimed to determine the distinctive features of large number of class or group. For this reason, a number of methods to generate multiclass SVMs from binary SVMs have been proposed by researchers and this is still a continuing research topic. In this study we aimed to compare classification accuracy and computational cost of four multiclass approaches using a original and simulated data sets. Error Corrected Output Coding (ECOC) based multiclass approaches that is used in this study creates many binary classifiers and combines their results to determine the class label of a test pixel. As a result of the comparisons for all conditions examined in this study, it's found that the classification accuracy and computational cost of One vs. One multiclass approach is better than the other multiclass approaches. In classification or pattern recognization problems, some of supervised machine learning methods or algorithms can be easily extended to multiclass problems. However, some other powerful and popular classifiers, such as AdaBoost and Support Vector Machines, do not extend to multiclass easily. In those situations, the usual way to proceed is to reduce the complexity of the multiclass problem into multiple simpler binary classification problems.

PM&R, 2014

Juvenile rheumatoid arthritis (JRA) is the most common rheumatologic disease in children. Moreove... more Juvenile rheumatoid arthritis (JRA) is the most common rheumatologic disease in children. Moreover, multiple sclerosis (MS) is the most frequent demyelinating disease and has been associated with various chronic inflammatory diseases. However, its association with JRA has not been frequently described. Autoimmunity in both JRA and MS has been documented in the scientific literature, although there has been no definitive finding that patients with JRA are prone to the development of MS. An increasing frequency of MS resulting from an increased use of antitumor necrosis factor agents in the treatment of rheumatoid arthritis and other chronic inflammatory diseases has been reported recently. In this study, we report on the development of MS in a patient with JRA who did not have a history of antitumor necrosis factor use.

International Journal of Cardiology, 2012

Background: The aim of this study was to investigate left atrial (LA) mechanical functions, atria... more Background: The aim of this study was to investigate left atrial (LA) mechanical functions, atrial electromechanical delay and P wave dispersion in hypothyroid patients. Methods: Thirty-four patients with overt hypothyroid and thirty controls were included. A diagnosis of overt hypothyroid was reached with increased serum TSH and decreased free T4 (fT4) levels. LA volumes were measured using the biplane area length method and LA active and passive emptying volumes and fraction were calculated. Intra-and interatrial electromechanical delay (EMD) were measured by tissue Doppler imaging (TDI). P wave dispersion was calculated by 12 lead electrocardiograms. Results: LA diameter were significantly higher in patients with overt hypothyroid (p = 0.021). LA passive emptying volume and LA passive emptying fraction were significantly decreased with hypothyroid patients (p = 0.002 and p < 0.001). LA active emptying volume and LA active emptying fraction were significantly increased with hypothyroid patients (p < 0.001 and p < 0.001). Intra-and interatrial EMD, were measured significantly higher in hypothyroid

Journal of Clinical and Experimental …

DOAJ Directory of Open Access Journals, SPARC Europe Award 2009 English. Free, full text, quality... more DOAJ Directory of Open Access Journals, SPARC Europe Award 2009 English. Free, full text, quality controlled scientific and scholarly journals, covering all subjects and many languages. ...