Debbie Quain - Academia.edu (original) (raw)

Papers by Debbie Quain

Wiley-Blackwell Publishing Asia, 2010

Supplemental Material for Contemporary prognosis of transient ischemic attack patients: A systema... more Supplemental Material for Contemporary prognosis of transient ischemic attack patients: A systematic review and meta-analysis by Nashwa Najib Parker Magin, Daniel Lasserson, Debbie Quain, John Attia, Christopher Oldmeadow, Carlos Garcia-Esperon and Christopher Levi in International Journal of Stroke

Supplemental Material for The International comparison of Systems of care and patient outcomes In... more Supplemental Material for The International comparison of Systems of care and patient outcomes In minor Stroke and Tia (InSIST) study: A community-based cohort study by Christopher R Levi, Daniel Lasserson, Debbie Quain, Jose Valderas, Helen M Dewey, P Alan Barber, Neil Spratt, Dominique A Cadilhac, Valery Feigin, Hossein Zareie, Carlos Garcia Esperon, Andrew Davey, Nashwa Najib and Parker Magin in International Journal of Stroke

International Journal of Stroke, 2019

Rationale Rapid response by health-care systems for transient ischemic attack and minor stroke (T... more Rationale Rapid response by health-care systems for transient ischemic attack and minor stroke (TIA/mS) is recommended to maximize the impact of secondary prevention strategies. The applicability of this evidence to Australian non-hospital-based TIA/mS management is uncertain. Aims Within an Australian community setting we seek to document processes of care, establish determinants of access to care, establish attack rates and determinants of recurrent vascular events and other clinical outcomes, establish the performance of ABC2-risk stratification, and compare the processes of care and outcomes to those in the UK and New Zealand for TIA/mS. Sample size estimates Recruiting practices containing approximately 51 full-time-equivalent general practitioners to recruit 100 TIA/mS per year over a four-year study period will provide sufficient power for each of our outcomes. Methods and design An inception cohort study of patients with possible TIA/mS recruited from 16 general practices in...

International Journal of Stroke, 2012

Introduction Anterior cerebral artery flow diversion, measured by transcranial Doppler ultrasound... more Introduction Anterior cerebral artery flow diversion, measured by transcranial Doppler ultrasound, is correlated with leptomeningeal collateral flow on digital subtraction angiography in the setting of middle cerebral artery occlusion. We aimed to assess the influence of flow diversion as a marker of leptomeningeal collateralization on infarct size and penumbral volume. Methods We assessed consecutive patients presenting within six-hours of ischaemic stroke. Anterior cerebral artery flow diversion, defined as ipsilateral mean velocity of at least 30% greater than the contralateral artery, was used as the Doppler index of leptomeningeal collateralization. Multivariable regression analysis was performed to assess the impact of anterior cerebral artery flow diversion, controlling for other important clinical variables. Leptomeningeal collateralization was also graded on computed tomography angiography. Infarct core and penumbral volumes were defined using computed tomography perfusion ...

HNE, 2011

... Louise-Anne Jordan, Debbie Quain, Di Marsden, Jenni White, Kathy Bullen, Sally Wright, Renae ... more ... Louise-Anne Jordan, Debbie Quain, Di Marsden, Jenni White, Kathy Bullen, Sally Wright, Renae Galvin, Judith Dunne, Helen Baines Hunter New England Health Page 7. ... British Medical Journal, 331, 1226. Meng, N., Lo, S., Chou, L., Yang, P., Chang, C. & Chou, E.(2010). ...

HNE, 2009

INTRODUCTION Stroke is Australia's most common cause of adult disability and one of the lead... more INTRODUCTION Stroke is Australia's most common cause of adult disability and one of the leading causes of death. Annually 53,000 Aus-tralians suffer a stroke. Of these, two people in three will die or be left with permanent disability, resulting in a huge soci-etal burden (Hankey, ...

are in a stroke unit improves longterm outcomes for stroke patients, underpinning the enhanced or... more are in a stroke unit improves longterm outcomes for stroke patients, underpinning the enhanced organisation of stroke services now underway across Australia.

International Journal of Stroke

Medical Journal of Australia, Oct 20, 2008

To assess the effectiveness of the PAST (Pre-hospital Acute Stroke Triage) protocol in reducing p... more To assess the effectiveness of the PAST (Pre-hospital Acute Stroke Triage) protocol in reducing pre-hospital and emergency department (ED) delays to patients receiving organised acute stroke care, thereby increasing access to thrombolytic therapy. Prospective cohort study using historical controls. Hunter Region of New South Wales, September 2005 to March 2006 (pre-intervention) and September 2006 to March 2007 (post-intervention). Consecutive patients presenting with acute stroke to a regional, tertiary referral hospital. PAST protocol, comprising a pre-hospital stroke assessment tool for ambulance officers, an ambulance protocol for hospital bypass for potentially thrombolysis-eligible patients, and pre-hospital notification of the acute stroke team. Proportion of patients who received intravenous tissue plasminogen activator (tPA), process of care time points (symptom onset to ED arrival, ED arrival to tPA treatment, and ED transit time), and clinical outcomes of patients treated...

Australian Journal of Primary Health, 2019

Journal of primary health care, 2021

INTRODUCTION Over-prescription of antibiotics for common infective conditions is an important hea... more INTRODUCTION Over-prescription of antibiotics for common infective conditions is an important health issue. Infective conjunctivitis represents one of the most common eye-related complaints in general practice. Despite its self-limiting nature, there is evidence of frequent general practitioner (GP) antibiotic prescribing for this condition, which is inconsistent with evidence-based guidelines. AIM To investigate the prevalence and associations of GP registrars' (trainees') prescription of antibiotics for infective conjunctivitis. METHODS We performed a cross-sectional analysis of the Registrar Encounters in Clinical Training (ReCEnT) ongoing prospective cohort study, which documents GP registrars' clinical consultations (involving collection of information from 60 consecutive consultations, at three points during registrar training). The outcome of the analyses was antibiotic prescription for a new diagnosis of conjunctivitis. Patient, registrar, practice and consultati...

International Journal of Stroke, 2015

Introduction: It is crucial to enhance timely treatment and secondary prevention following a tran... more Introduction: It is crucial to enhance timely treatment and secondary prevention following a transient ischaemic attack (TIA) and one way to ensure this is to improve the accuracy and promptness of diagnosis. Unfortunately, initiating timely treatment can be difficult due to patients’ lack of knowledge of symptoms and their need for urgency, and difficulties in obtaining this diagnosis. Understanding the TIA event from the patient’s perceptive may open the door to a better understanding of TIA symptomology and improve current difficulties with diagnosis. Method: Narratives of 123 participants, adjudicated to have experienced a TIA, were selected from a TIA/minor stroke cohort assembled by the International Study of Systems of Care in Minor Stroke and TIA [InSiST] study. This National Health and Medical Research Council (NHMRC) funded study is currently underway in NSW, Australia. The participants’ TIA experiences were transcribed into narratives, and using constructivist thematic an...

Deprescribing is the health‐professional‐supervised process of withdrawal of an inappropriate med... more Deprescribing is the health‐professional‐supervised process of withdrawal of an inappropriate medication to manage polypharmacy and improve patient outcomes. Given the harms of polypharmacy and associated inappropriate medicines, practitioners, especially general practitioners (GPs), are encouraged to take a proactive role in deprescribing in older patients. While trial evidence for benefits of deprescribing is accumulating, there is currently little epidemiologic evidence of clinicians’ (including GPs’) deprescribing behaviours. We aimed to establish the prevalence and explore associations of deprescribing of inappropriate medicines by early‐career GPs.