Diana Istrate - Academia.edu (original) (raw)

Papers by Diana Istrate

Research paper thumbnail of Gaps or links between hormonal therapy and schizophrenia? (Review)

Experimental and Therapeutic Medicine, 2020

Schizophrenia is considered the most severe and debilitating psychiatric disorder. During the 80&... more Schizophrenia is considered the most severe and debilitating psychiatric disorder. During the 80's, first reports on abnormalities of the schizophrenic brain which could be objectively observed on MRI, CT scans and other imagistic techniques were published. This showed that schizophrenia is a disorder that goes beyond the functional aspect of the symptomatology. The ties between psychiatry and endocrinology are easily observed, even empirically, by any mental health practitioner, and mirrored by endocrinology specialists. Disorders related to menstruation phase of the menstrual cycle have a code in DSM-V, people expect women ‘to have mental disturbances’ during puberty, pregnancy, menopause and other periods of life known to cause a hormonal storm. Leaving aside those simple and common beliefs, any mental health specialist can observe the differences between men and women when it comes to psychopathology, and the differences between male and female patients when it comes to a se...

Research paper thumbnail of Paranoid Schizophrenia from a Philosophical Perspective

Open Journal of Social Sciences

Motivation: Paranoid schizophrenia, postulated in a macroscopic dimension, is conserved from cons... more Motivation: Paranoid schizophrenia, postulated in a macroscopic dimension, is conserved from consumption of the selves, perception, volition, cognition, affect, thought and behavior. The intense study of this condition, as well as the absence of a theory for the mechanism of occurrence, gives it its own aura that seems to absorb the normality known as a characteristic of the Self and transform it into a progressive disharmony, accentuated by acute psychotic episodes and "selective dehumanization". Objective: Presentation of a patient aged 35, with a psychiatric history and symptomatology started ten years ago. It was pharmacologically approached seven years ago with Escitalopram, Buspirone and Clonazepam, but the paranoid background culminated in his being admitted to a closed psychiatric regime (surveillance, "key room") three weeks after the apparent depressive episode. Material and method: Psychiatric evaluation, treatment initiation, psychological evaluation, excluding brain organics, evaluation of intrapsychic dynamics, observations. Results: The patient functions in the paranoid registry, being dominated by pseudo-hallucinations, ideas from the spectrum of xenopathy and control, joining formal and content disorders (circumstantial discourse, tangentiality). It associates the patina of the speech, illogical constructions, the impossibility of materializing the thoughts, the repeated jump between the abstract and concrete levels. He is so deeply immersed in his own ideas about honor, confabulation and self-control, which we "lose" him in what he claims to be: a "complex in continuous development". Conclusions: He describes himself as a warrior whose vein is supported by a willing Ego at all times to disintegrate. It is not compliant with the drug treatment, arguing that it "disturbs me and gives me changes of concentration", which destabilizes and disorganizes a possible ascent in the process of systematizing and engaging the thinking in a near normality.

Research paper thumbnail of Gaps or links between hormonal therapy and schizophrenia? (Review)

Experimental and Therapeutic Medicine, 2020

Schizophrenia is considered the most severe and debilitating psychiatric disorder. During the 80&... more Schizophrenia is considered the most severe and debilitating psychiatric disorder. During the 80's, first reports on abnormalities of the schizophrenic brain which could be objectively observed on MRI, CT scans and other imagistic techniques were published. This showed that schizophrenia is a disorder that goes beyond the functional aspect of the symptomatology. The ties between psychiatry and endocrinology are easily observed, even empirically, by any mental health practitioner, and mirrored by endocrinology specialists. Disorders related to menstruation phase of the menstrual cycle have a code in DSM-V, people expect women ‘to have mental disturbances’ during puberty, pregnancy, menopause and other periods of life known to cause a hormonal storm. Leaving aside those simple and common beliefs, any mental health specialist can observe the differences between men and women when it comes to psychopathology, and the differences between male and female patients when it comes to a se...

Research paper thumbnail of Paranoid Schizophrenia from a Philosophical Perspective

Open Journal of Social Sciences

Motivation: Paranoid schizophrenia, postulated in a macroscopic dimension, is conserved from cons... more Motivation: Paranoid schizophrenia, postulated in a macroscopic dimension, is conserved from consumption of the selves, perception, volition, cognition, affect, thought and behavior. The intense study of this condition, as well as the absence of a theory for the mechanism of occurrence, gives it its own aura that seems to absorb the normality known as a characteristic of the Self and transform it into a progressive disharmony, accentuated by acute psychotic episodes and "selective dehumanization". Objective: Presentation of a patient aged 35, with a psychiatric history and symptomatology started ten years ago. It was pharmacologically approached seven years ago with Escitalopram, Buspirone and Clonazepam, but the paranoid background culminated in his being admitted to a closed psychiatric regime (surveillance, "key room") three weeks after the apparent depressive episode. Material and method: Psychiatric evaluation, treatment initiation, psychological evaluation, excluding brain organics, evaluation of intrapsychic dynamics, observations. Results: The patient functions in the paranoid registry, being dominated by pseudo-hallucinations, ideas from the spectrum of xenopathy and control, joining formal and content disorders (circumstantial discourse, tangentiality). It associates the patina of the speech, illogical constructions, the impossibility of materializing the thoughts, the repeated jump between the abstract and concrete levels. He is so deeply immersed in his own ideas about honor, confabulation and self-control, which we "lose" him in what he claims to be: a "complex in continuous development". Conclusions: He describes himself as a warrior whose vein is supported by a willing Ego at all times to disintegrate. It is not compliant with the drug treatment, arguing that it "disturbs me and gives me changes of concentration", which destabilizes and disorganizes a possible ascent in the process of systematizing and engaging the thinking in a near normality.