Dina Baga - Academia.edu (original) (raw)

Papers by Dina Baga

Research paper thumbnail of PERFORM: A system for the continuous remote monitoring of patients with neurodegenerative diseases and the objective evaluation of patient status

Research paper thumbnail of A Wearable Ultrasound Device for the Monitoring and Acceleration of Bone Fracture Healing

Introduction Several methods for the acceleration of the healing process have been used, includin... more Introduction Several methods for the acceleration of the healing process have been used, including electrical stimulation. Electromagnetic fields (EMFs) have direct biological effects on endochondrial cells and enhance the formation of callus (Gupta et al., 1991). Ultrasound is currently used for the diagnosis of osteoporosis (R. Strelitzki et. al., 1996). In this case, two ultrasound transducers are placed on the skin, on opposite sites of the bone sample and the transition time of ultrasound waves is measured. In a recent study (C. Malizos et. Al., 1999) the use of ultrasound waves was proposed to enhance callus formation. In this work, the architectural design of a personalized wearable device for the monitoring and acceleration of bone fracture healing using ultrasound signals is presented. The proposed wearable device is plugged onto an external fixator and the traducers are placed directly on the surface of the bone. The proposed system can be used for the acceleration, as wel...

Research paper thumbnail of PERFORM: A platform for monitoring and management of chronic neurodegenerative diseases: The Parkinson and Amyotrophic Lateral Sclerosis case

2009 4th International IEEE/EMBS Conference on Neural Engineering, 2009

... Maria Teresa Arrendondo, Juan Jacobo Estrada, Mario Pansera Polytechnic University of Madrid ... more ... Maria Teresa Arrendondo, Juan Jacobo Estrada, Mario Pansera Polytechnic University of Madrid Madrid, Spain mta@lst.tfo.upm.es, jjestrada@lst.tfo ... Sensors on the arms and legs are attached on specially designed elastic bands with Velcro, which allow fixation to any wrist or ...

Research paper thumbnail of Assessment of Tremor Activity in the Parkinson’s Disease Using a Set of Wearable Sensors

IEEE Transactions on Information Technology in Biomedicine, 2012

Tremor is the most common motor disorder of Parkinson&amp... more Tremor is the most common motor disorder of Parkinson's disease (PD) and consequently its detection plays a crucial role in the management and treatment of PD patients. The current diagnosis procedure is based on subject-dependent clinical assessment, which has a difficulty in capturing subtle tremor features. In this paper, an automated method for both resting and action/postural tremor assessment is proposed using a set of accelerometers mounted on different patient's body segments. The estimation of tremor type (resting/action postural) and severity is based on features extracted from the acquired signals and hidden Markov models. The method is evaluated using data collected from 23 subjects (18 PD patients and 5 control subjects). The obtained results verified that the proposed method successfully: 1) quantifies tremor severity with 87 % accuracy, 2) discriminates resting from postural tremor, and 3) discriminates tremor from other Parkinsonian motor symptoms during daily activities.

Research paper thumbnail of Using partial decision trees to predict Parkinson’s symptoms: A new approach for diagnosis and therapy in patients suffering from Parkinson’s disease

Computers in Biology and Medicine, 2012

Research paper thumbnail of PERFORM: First steps in the assessment of patient motion status and support to treatment changes

In the current work, a system for the monitoring, assessment and management of patients with chro... more In the current work, a system for the monitoring, assessment and management of patients with chronic movement disorders such as Parkinson's disease (PD) is presented. The so called PERFORM system consists of the patient and the healthcare center subsystem. PERFORM monitors patient's motion status in daily activities, using a set of light wearable sensors. Based on the analysis of the

Research paper thumbnail of A decision support tool for optimal Levodopa administration in Parkinson's Disease

In this work a decision support tool for optimal administration of Levodopa (L-Dopa) in patients ... more In this work a decision support tool for optimal administration of Levodopa (L-Dopa) in patients with Parkinson's Disease (PD) is presented. The so called Medication Change Proposer (MCP) is part of the PERFORM system, which monitors patient's motion status using a set of wearable sensors, assesses PD symptoms and their severity through dedicated symptoms detection modules (On-Off detection and Levodopa-Induced

Research paper thumbnail of An Ultrasound Wearable System for the Monitoring and Acceleration of Fracture Healing in Long Bones

Abstract—An ultrasound wearable system for remote moni-toring and acceleration of the healing pro... more Abstract—An ultrasound wearable system for remote moni-toring and acceleration of the healing process in fractured long bones is presented. The so-called USBone system consists of a pair of ultrasound transducers, implanted into the fracture region, a wearable device and a centralized unit. The wearable device is responsible to carry out ultrasound measurements using the axial-transmission technique and initiate therapy sessions of low-intensity pulsed ultrasound. The acquired measurements and other data are wirelessly transferred from the patient-site to the centralized unit, which is located in a clinical setting. The evaluation of the system on an animal tibial osteotomy model is also presented. A dataset was constructed for monitoring pur-poses consisting of serial ultrasound measurements, follow-up radiographs, quantitative computed tomography-based densito-metry and biomechanical data. The animal study demonstrated the ability of the system to collect ultrasound measurements i...

Research paper thumbnail of PERFORM: Building and Mining Electronic Records of Neurological Patients Being Monitored in the Home

The PERFORM project is building a novel application for the home-based monitoring and assessment ... more The PERFORM project is building a novel application for the home-based monitoring and assessment of people with neurologically based movement disorders such as Parkinson’s disease (PD) and Amyotrophic Lateral Sclerosis (ALS). PERFORM includes a hospital-based EHR data-analysis and mining system compatible with HL7. For EHR to include monitoring data an alert-based system of data reduction is used which supports both patient management and modelling. Pilots will be started in Spain, Greece and Italy in 2009. PERFORM is in the early stages of development and is an FP7 integrated project.

Research paper thumbnail of PERFORM: A system for the monitoring and management of persons with chronic motor neurodegenerative disorders: A study on Parkinson's Disease and Amyotrophic Lateral Sclerosis

Proceedings of the 3d International ICST Conference on Pervasive Computing Technologies for Healthcare, 2009

ABSTRACT In this work we describe a system for the monitoring and management of patients with neu... more ABSTRACT In this work we describe a system for the monitoring and management of patients with neurodegenerative diseases, focusing on Parkinson's Disease and Amyotrophic Lateral Sclerosis. The system exploits a single wearable sensors' setting to detect and quantify all patient symptoms. An easy to use touchscreen interface allows patients and caregivers to provide additional useful information and assist patients to perform standard predefined tests which otherwise are performed in the clinician's office. The system exploits patient information to suggest appropriate treatment changes based on accumulated medical knowledge. In this paper the architecture of the system, as well as, its innovative features are presented.

Research paper thumbnail of An Automated Method for the Monitoring and Evaluation of Long Bones Fracture Healing

ABSTRACT An automated diagnosis method is proposed for the monitoring of the fracture healing of ... more ABSTRACT An automated diagnosis method is proposed for the monitoring of the fracture healing of long bones. The method consists of an ultrasound sensing module and an intelligent module. The sensing system is based on a semi-invasive application of ultrasound. Two ultrasound transducers are mounted onto the bone surface, on opposite sides of the fracture site, one acting as transmitter and the other as receiver (through-transmission mode). The transmitter sends out a short pulse (of 500KHz central frequency), which propagates along the long axis of the bone, crosses the fracture site and is then captured by the receiver. In this paper, in vitro fracture models have been studied, using dead lamb tibiae. Osteotomy is carried out to the tibiae and the bony fragments are then held together by an external fixator. The healing process has been simulated by various biological materials, which fill the fracture gap and mimic callus maturation. A large and systematic dataset of ultrasound measurements (containing the signal waveform and the propagation velocity of each bone) has been constructed. The intelligent system takes as input ultrasound measurements from a fractured bone and its role is to provide an estimation of the healing progress. For the construction of the intelligent system, various data-driven classifiers have been studied.

Research paper thumbnail of PERFORM: A system for the continuous remote monitoring of patients with neurodegenerative diseases and the objective evaluation of patient status

Research paper thumbnail of A Wearable Ultrasound Device for the Monitoring and Acceleration of Bone Fracture Healing

Introduction Several methods for the acceleration of the healing process have been used, includin... more Introduction Several methods for the acceleration of the healing process have been used, including electrical stimulation. Electromagnetic fields (EMFs) have direct biological effects on endochondrial cells and enhance the formation of callus (Gupta et al., 1991). Ultrasound is currently used for the diagnosis of osteoporosis (R. Strelitzki et. al., 1996). In this case, two ultrasound transducers are placed on the skin, on opposite sites of the bone sample and the transition time of ultrasound waves is measured. In a recent study (C. Malizos et. Al., 1999) the use of ultrasound waves was proposed to enhance callus formation. In this work, the architectural design of a personalized wearable device for the monitoring and acceleration of bone fracture healing using ultrasound signals is presented. The proposed wearable device is plugged onto an external fixator and the traducers are placed directly on the surface of the bone. The proposed system can be used for the acceleration, as wel...

Research paper thumbnail of PERFORM: A platform for monitoring and management of chronic neurodegenerative diseases: The Parkinson and Amyotrophic Lateral Sclerosis case

2009 4th International IEEE/EMBS Conference on Neural Engineering, 2009

... Maria Teresa Arrendondo, Juan Jacobo Estrada, Mario Pansera Polytechnic University of Madrid ... more ... Maria Teresa Arrendondo, Juan Jacobo Estrada, Mario Pansera Polytechnic University of Madrid Madrid, Spain mta@lst.tfo.upm.es, jjestrada@lst.tfo ... Sensors on the arms and legs are attached on specially designed elastic bands with Velcro, which allow fixation to any wrist or ...

Research paper thumbnail of Assessment of Tremor Activity in the Parkinson’s Disease Using a Set of Wearable Sensors

IEEE Transactions on Information Technology in Biomedicine, 2012

Tremor is the most common motor disorder of Parkinson&amp... more Tremor is the most common motor disorder of Parkinson's disease (PD) and consequently its detection plays a crucial role in the management and treatment of PD patients. The current diagnosis procedure is based on subject-dependent clinical assessment, which has a difficulty in capturing subtle tremor features. In this paper, an automated method for both resting and action/postural tremor assessment is proposed using a set of accelerometers mounted on different patient's body segments. The estimation of tremor type (resting/action postural) and severity is based on features extracted from the acquired signals and hidden Markov models. The method is evaluated using data collected from 23 subjects (18 PD patients and 5 control subjects). The obtained results verified that the proposed method successfully: 1) quantifies tremor severity with 87 % accuracy, 2) discriminates resting from postural tremor, and 3) discriminates tremor from other Parkinsonian motor symptoms during daily activities.

Research paper thumbnail of Using partial decision trees to predict Parkinson’s symptoms: A new approach for diagnosis and therapy in patients suffering from Parkinson’s disease

Computers in Biology and Medicine, 2012

Research paper thumbnail of PERFORM: First steps in the assessment of patient motion status and support to treatment changes

In the current work, a system for the monitoring, assessment and management of patients with chro... more In the current work, a system for the monitoring, assessment and management of patients with chronic movement disorders such as Parkinson's disease (PD) is presented. The so called PERFORM system consists of the patient and the healthcare center subsystem. PERFORM monitors patient's motion status in daily activities, using a set of light wearable sensors. Based on the analysis of the

Research paper thumbnail of A decision support tool for optimal Levodopa administration in Parkinson's Disease

In this work a decision support tool for optimal administration of Levodopa (L-Dopa) in patients ... more In this work a decision support tool for optimal administration of Levodopa (L-Dopa) in patients with Parkinson's Disease (PD) is presented. The so called Medication Change Proposer (MCP) is part of the PERFORM system, which monitors patient's motion status using a set of wearable sensors, assesses PD symptoms and their severity through dedicated symptoms detection modules (On-Off detection and Levodopa-Induced

Research paper thumbnail of An Ultrasound Wearable System for the Monitoring and Acceleration of Fracture Healing in Long Bones

Abstract—An ultrasound wearable system for remote moni-toring and acceleration of the healing pro... more Abstract—An ultrasound wearable system for remote moni-toring and acceleration of the healing process in fractured long bones is presented. The so-called USBone system consists of a pair of ultrasound transducers, implanted into the fracture region, a wearable device and a centralized unit. The wearable device is responsible to carry out ultrasound measurements using the axial-transmission technique and initiate therapy sessions of low-intensity pulsed ultrasound. The acquired measurements and other data are wirelessly transferred from the patient-site to the centralized unit, which is located in a clinical setting. The evaluation of the system on an animal tibial osteotomy model is also presented. A dataset was constructed for monitoring pur-poses consisting of serial ultrasound measurements, follow-up radiographs, quantitative computed tomography-based densito-metry and biomechanical data. The animal study demonstrated the ability of the system to collect ultrasound measurements i...

Research paper thumbnail of PERFORM: Building and Mining Electronic Records of Neurological Patients Being Monitored in the Home

The PERFORM project is building a novel application for the home-based monitoring and assessment ... more The PERFORM project is building a novel application for the home-based monitoring and assessment of people with neurologically based movement disorders such as Parkinson’s disease (PD) and Amyotrophic Lateral Sclerosis (ALS). PERFORM includes a hospital-based EHR data-analysis and mining system compatible with HL7. For EHR to include monitoring data an alert-based system of data reduction is used which supports both patient management and modelling. Pilots will be started in Spain, Greece and Italy in 2009. PERFORM is in the early stages of development and is an FP7 integrated project.

Research paper thumbnail of PERFORM: A system for the monitoring and management of persons with chronic motor neurodegenerative disorders: A study on Parkinson's Disease and Amyotrophic Lateral Sclerosis

Proceedings of the 3d International ICST Conference on Pervasive Computing Technologies for Healthcare, 2009

ABSTRACT In this work we describe a system for the monitoring and management of patients with neu... more ABSTRACT In this work we describe a system for the monitoring and management of patients with neurodegenerative diseases, focusing on Parkinson's Disease and Amyotrophic Lateral Sclerosis. The system exploits a single wearable sensors' setting to detect and quantify all patient symptoms. An easy to use touchscreen interface allows patients and caregivers to provide additional useful information and assist patients to perform standard predefined tests which otherwise are performed in the clinician's office. The system exploits patient information to suggest appropriate treatment changes based on accumulated medical knowledge. In this paper the architecture of the system, as well as, its innovative features are presented.

Research paper thumbnail of An Automated Method for the Monitoring and Evaluation of Long Bones Fracture Healing

ABSTRACT An automated diagnosis method is proposed for the monitoring of the fracture healing of ... more ABSTRACT An automated diagnosis method is proposed for the monitoring of the fracture healing of long bones. The method consists of an ultrasound sensing module and an intelligent module. The sensing system is based on a semi-invasive application of ultrasound. Two ultrasound transducers are mounted onto the bone surface, on opposite sides of the fracture site, one acting as transmitter and the other as receiver (through-transmission mode). The transmitter sends out a short pulse (of 500KHz central frequency), which propagates along the long axis of the bone, crosses the fracture site and is then captured by the receiver. In this paper, in vitro fracture models have been studied, using dead lamb tibiae. Osteotomy is carried out to the tibiae and the bony fragments are then held together by an external fixator. The healing process has been simulated by various biological materials, which fill the fracture gap and mimic callus maturation. A large and systematic dataset of ultrasound measurements (containing the signal waveform and the propagation velocity of each bone) has been constructed. The intelligent system takes as input ultrasound measurements from a fractured bone and its role is to provide an estimation of the healing progress. For the construction of the intelligent system, various data-driven classifiers have been studied.