Dina Shehab - Academia.edu (original) (raw)

Papers by Dina Shehab

Research paper thumbnail of Impact of Obesity and Physical Inactivity among Children

International journal of food, nutrition and public health, Jun 13, 2019

Research paper thumbnail of Prevalence of metabolic syndrome and insulin resistance among Egyptian adolescents 10 to 18 years of age

Journal of Clinical Lipidology, May 1, 2010

The prevalence and magnitude of childhood obesity are increasing dramatically. To examine the eff... more The prevalence and magnitude of childhood obesity are increasing dramatically. To examine the effect of varying social, demographic, dietary, and activity factors on the prevalence of metabolic syndrome and its relation to insulin resistance, C-reactive protein, and homocysteine levels in a large, representative sample of Egyptian adolescents. Our survey included 4250 adolescents (from 10 to 18 years of age; male subjects comprised 42.5% of participants) from 7 governorates representing Egypt. Baseline measurements included blood pressure, fasting blood glucose, plasma lipids, C-reactive protein, and homocysteine levels. Because the body mass index varies according to age, we standardized the value for age and sex with the use of conversion to percentiles. The overall prevalence of the metabolic syndrome was 7.4% with no sex or area of residence predilection. Results showed that adolescents with the full criteria of metabolic syndrome (ie, three criterion or more) constituted nearly one fourth of those exhibiting high values of different components, except for systolic blood pressure, where they were 42%, and TG, where they were 31%. Family history of obesity and diabetes mellitus increase the odds for metabolic syndrome significantly (1.68 and 1.3, respectively) as well as inactivity. A high level of C-reactive protein was reported among affected adolescents. Homocysteine level did not have an influence. The prevalence of the metabolic syndrome is considerable among obese adolescents. Proinflammatory markers associated with an increased risk of adverse cardiovascular outcomes are already present in these youth.

Research paper thumbnail of Prevalence of overweight and obesity, and status of chronic non- communicable diseases and some related risk factors among Egyptian adolescents

Journal of Diabetes and Endocrinology, Dec 15, 2011

Obesity is a major threat to children's health today. The prevalence of obesity has been steadily... more Obesity is a major threat to children's health today. The prevalence of obesity has been steadily increasing; over the past 25 years, the number of obese children has nearly tripled and is more likely to have risk factors for cardiovascular disease, such as type 2 diabetes high cholesterol or high blood pressure. Research objectives were to study the current prevalence of overweight and obesity among adolescents in Egypt from 2000 to 2008, to estimate the prevalence of glucose disorders, hypertension, lipid profile, and metabolic syndrome, and to investigate some related risk factors among 10 to 18 years old school adolescents. For assessing prevalence rates of overweight and obesity among adolescents, data from reports of other cross-sectional studies carried out by National Nutrition Institute (NNI) (2000 to 2005) and Egypt Demographic and Health Survey (2008) were compared. To estimate the prevalence of glucose disorders, hypertension, lipid profile, and metabolic syndrome, a randomized stratified cluster-sample of preparatory and secondary school students was used. Body mass index (BMI) was calculated and referred to corresponding international reference values for age and sex. A fasting blood sample was drawn to assess lipid profile and fasting plasma insulin. Overweight and obesity are prevalent among Egyptian adolescents of both sexes, and at least, for girls, the prevalence has increased in the last few years. Pre-diabetic state was present among 16.4% of adolescents. The crude prevalence of hypertension is 1.4%. The overall proportion of adolescents with high total cholesterol is 6.0%; the proportion with high lower density lipoprotein (LDL)-cholesterol is 7.5%, with high triglycerides of 8.2%, and low higher density lipoprotein (HDL) cholesterol of 9.4%. We conclude that overweight and obesity, type 2 diabetes mellitus (T2DM), hypertension and cardiovascular risk factors in young are serious in terms of morbidity and mortality, suggesting that they are an appropriate target for screening.

Research paper thumbnail of Celiac disease

The Egyptian Journal of Internal Medicine

Purpose of review The aim of this review was to summarize recent advances in celiac disease (CD) ... more Purpose of review The aim of this review was to summarize recent advances in celiac disease (CD) published between 2006 and 2012. Recent findings CD affects ~ 1% of most populations but remains largely unrecognized. During the past year, research has shown that the prevalence of CD has increased dramatically and not merely because of increased detection. Moreover, undiagnosed CD may be associated with increased mortality. Significant progress has been made in understanding how gliadin peptides can cross the intestinal border and access the immune system. New deamidated gliadin peptide antibodies have better diagnostic accuracy over other tests. The inclusion of duodenal bulb biopsy specimens may increase the rate of CD detection. Finally, refractory CD, although rare, is associated with a poor prognosis. The use of novel highly efficient exogenous prolyl endoproteases enzymes may help patients deal with occasional lapses in their diet or may protect highly sensitive individuals from...

Research paper thumbnail of ISSN 2141-2685 ©2010 Academic Journals

Prevalence of overweight and obesity, and status of chronic non- communicable diseases and some r... more Prevalence of overweight and obesity, and status of chronic non- communicable diseases and some related risk factors among Egyptian adolescents

Research paper thumbnail of Impact of Obesity and Physical Inactivity among Children

International Journal of Food, Nutrition and Public Health, 2019

Research paper thumbnail of Metabolic Response to Dietary Restriction in Some Inborn Errors of Amino Acids

Background: Genetic diseases, though individually rare, are cumulatively frequent enough to be re... more Background: Genetic diseases, though individually rare, are cumulatively frequent enough to be responsible for up to 42% of deaths within the first year of life and to make a significant contribution to the 1% of children of school age with physical handicap and the 0.3% with severe learning difficulties. Study Aim: Assessment of metabolic and nutritional status before and after nutrition education program (NEP). Subjects and Methods: A total number of 30 child (17 girls and 13 boys), of those attending the outpatient clinic of "Dietary Intervention of Inborn errors of Metabolism" at the National Nutrition Institute, Cairo, were selected. They were mainly referred from Children Hospital, Kasr El-Ainy and they were suffering from one of the three amino acid disorders; hyperammonia, aminoacidopathy, and organic acidurias. Sociodemographic data, food frequency pattern, 24-hour recall, morbidity recall, medical history and examination and anthropometric measurements were taken...

Research paper thumbnail of Prevalence of overweight and obesity, and status of chronic non- communicable diseases and some related risk factors among Egyptian adolescents

Obesity is a major threat to children's health today. The prevalence of obesity has been stea... more Obesity is a major threat to children's health today. The prevalence of obesity has been steadily increasing; over the past 25 years, the number of obese children has nearly tripled and is more likely to have risk factors for cardiovascular disease, such as type 2 diabetes high cholesterol or high blood pressure. Research objectives were to study the current prevalence of overweight and obesity among adolescents in Egypt from 2000 to 2008, to estimate the prevalence of glucose disorders, hypertension, lipid profile, and metabolic syndrome, and to investigate some related risk factors among 10 to 18 years old school adolescents. For assessing prevalence rates of overweight and obesity among adolescents, data from reports of other cross-sectional studies carried out by National Nutrition Institute (NNI) (2000 to 2005) and Egypt Demographic and Health Survey (2008) were compared. To estimate the prevalence of glucose disorders, hypertension, lipid profile, and metabolic syndrome, a...

Research paper thumbnail of Diet, Nutrition and Prevention of Type Two Diabetes Among Egyptian Adolescents

Journal of Nutrition Education and Behavior, 2009

Outcome, Measures and Analysis: Content analysis was used to determine recurring trends and theme... more Outcome, Measures and Analysis: Content analysis was used to determine recurring trends and themes from the focus groups and food photographs. Results: Most of the teens' stories revealed heavy reliance on and satisfaction with convenience foods because of their taste, cost, and availability. This was particularly true when eating with friends. Few participants assumed responsibility for making food choices that involved others in the family (e.g. grocery shopping or cooking). They expressed a reasonable understanding of healthy eating and its importance, yet lacked a sense of urgency in prioritizing healthy food choices, perceiving change towards a healthier diet undesirable or difficult. However, two girls in the group ate healthfully and were quite proud to share their value for health with the group. Conclusions and Implications: These results suggest that adolescent-targeted nutrition education alone will not succeed for most youth without also having environmental supports such as accessibility to fresh, healthy, affordable foods, family values around meals, positive school-based food experiences, and less media and marketing on unhealthful food and more on healthful foods. This project was supported by Teachers College and Liberty Program.

Research paper thumbnail of Prevalence of metabolic syndrome and insulin resistance among Egyptian adolescents 10 to 18 years of age

Journal of Clinical Lipidology, 2010

The prevalence and magnitude of childhood obesity are increasing dramatically. To examine the eff... more The prevalence and magnitude of childhood obesity are increasing dramatically. To examine the effect of varying social, demographic, dietary, and activity factors on the prevalence of metabolic syndrome and its relation to insulin resistance, C-reactive protein, and homocysteine levels in a large, representative sample of Egyptian adolescents. Our survey included 4250 adolescents (from 10 to 18 years of age; male subjects comprised 42.5% of participants) from 7 governorates representing Egypt. Baseline measurements included blood pressure, fasting blood glucose, plasma lipids, C-reactive protein, and homocysteine levels. Because the body mass index varies according to age, we standardized the value for age and sex with the use of conversion to percentiles. The overall prevalence of the metabolic syndrome was 7.4% with no sex or area of residence predilection. Results showed that adolescents with the full criteria of metabolic syndrome (ie, three criterion or more) constituted nearly one fourth of those exhibiting high values of different components, except for systolic blood pressure, where they were 42%, and TG, where they were 31%. Family history of obesity and diabetes mellitus increase the odds for metabolic syndrome significantly (1.68 and 1.3, respectively) as well as inactivity. A high level of C-reactive protein was reported among affected adolescents. Homocysteine level did not have an influence. The prevalence of the metabolic syndrome is considerable among obese adolescents. Proinflammatory markers associated with an increased risk of adverse cardiovascular outcomes are already present in these youth.

Research paper thumbnail of Impact of Obesity and Physical Inactivity among Children

International journal of food, nutrition and public health, Jun 13, 2019

Research paper thumbnail of Prevalence of metabolic syndrome and insulin resistance among Egyptian adolescents 10 to 18 years of age

Journal of Clinical Lipidology, May 1, 2010

The prevalence and magnitude of childhood obesity are increasing dramatically. To examine the eff... more The prevalence and magnitude of childhood obesity are increasing dramatically. To examine the effect of varying social, demographic, dietary, and activity factors on the prevalence of metabolic syndrome and its relation to insulin resistance, C-reactive protein, and homocysteine levels in a large, representative sample of Egyptian adolescents. Our survey included 4250 adolescents (from 10 to 18 years of age; male subjects comprised 42.5% of participants) from 7 governorates representing Egypt. Baseline measurements included blood pressure, fasting blood glucose, plasma lipids, C-reactive protein, and homocysteine levels. Because the body mass index varies according to age, we standardized the value for age and sex with the use of conversion to percentiles. The overall prevalence of the metabolic syndrome was 7.4% with no sex or area of residence predilection. Results showed that adolescents with the full criteria of metabolic syndrome (ie, three criterion or more) constituted nearly one fourth of those exhibiting high values of different components, except for systolic blood pressure, where they were 42%, and TG, where they were 31%. Family history of obesity and diabetes mellitus increase the odds for metabolic syndrome significantly (1.68 and 1.3, respectively) as well as inactivity. A high level of C-reactive protein was reported among affected adolescents. Homocysteine level did not have an influence. The prevalence of the metabolic syndrome is considerable among obese adolescents. Proinflammatory markers associated with an increased risk of adverse cardiovascular outcomes are already present in these youth.

Research paper thumbnail of Prevalence of overweight and obesity, and status of chronic non- communicable diseases and some related risk factors among Egyptian adolescents

Journal of Diabetes and Endocrinology, Dec 15, 2011

Obesity is a major threat to children's health today. The prevalence of obesity has been steadily... more Obesity is a major threat to children's health today. The prevalence of obesity has been steadily increasing; over the past 25 years, the number of obese children has nearly tripled and is more likely to have risk factors for cardiovascular disease, such as type 2 diabetes high cholesterol or high blood pressure. Research objectives were to study the current prevalence of overweight and obesity among adolescents in Egypt from 2000 to 2008, to estimate the prevalence of glucose disorders, hypertension, lipid profile, and metabolic syndrome, and to investigate some related risk factors among 10 to 18 years old school adolescents. For assessing prevalence rates of overweight and obesity among adolescents, data from reports of other cross-sectional studies carried out by National Nutrition Institute (NNI) (2000 to 2005) and Egypt Demographic and Health Survey (2008) were compared. To estimate the prevalence of glucose disorders, hypertension, lipid profile, and metabolic syndrome, a randomized stratified cluster-sample of preparatory and secondary school students was used. Body mass index (BMI) was calculated and referred to corresponding international reference values for age and sex. A fasting blood sample was drawn to assess lipid profile and fasting plasma insulin. Overweight and obesity are prevalent among Egyptian adolescents of both sexes, and at least, for girls, the prevalence has increased in the last few years. Pre-diabetic state was present among 16.4% of adolescents. The crude prevalence of hypertension is 1.4%. The overall proportion of adolescents with high total cholesterol is 6.0%; the proportion with high lower density lipoprotein (LDL)-cholesterol is 7.5%, with high triglycerides of 8.2%, and low higher density lipoprotein (HDL) cholesterol of 9.4%. We conclude that overweight and obesity, type 2 diabetes mellitus (T2DM), hypertension and cardiovascular risk factors in young are serious in terms of morbidity and mortality, suggesting that they are an appropriate target for screening.

Research paper thumbnail of Celiac disease

The Egyptian Journal of Internal Medicine

Purpose of review The aim of this review was to summarize recent advances in celiac disease (CD) ... more Purpose of review The aim of this review was to summarize recent advances in celiac disease (CD) published between 2006 and 2012. Recent findings CD affects ~ 1% of most populations but remains largely unrecognized. During the past year, research has shown that the prevalence of CD has increased dramatically and not merely because of increased detection. Moreover, undiagnosed CD may be associated with increased mortality. Significant progress has been made in understanding how gliadin peptides can cross the intestinal border and access the immune system. New deamidated gliadin peptide antibodies have better diagnostic accuracy over other tests. The inclusion of duodenal bulb biopsy specimens may increase the rate of CD detection. Finally, refractory CD, although rare, is associated with a poor prognosis. The use of novel highly efficient exogenous prolyl endoproteases enzymes may help patients deal with occasional lapses in their diet or may protect highly sensitive individuals from...

Research paper thumbnail of ISSN 2141-2685 ©2010 Academic Journals

Prevalence of overweight and obesity, and status of chronic non- communicable diseases and some r... more Prevalence of overweight and obesity, and status of chronic non- communicable diseases and some related risk factors among Egyptian adolescents

Research paper thumbnail of Impact of Obesity and Physical Inactivity among Children

International Journal of Food, Nutrition and Public Health, 2019

Research paper thumbnail of Metabolic Response to Dietary Restriction in Some Inborn Errors of Amino Acids

Background: Genetic diseases, though individually rare, are cumulatively frequent enough to be re... more Background: Genetic diseases, though individually rare, are cumulatively frequent enough to be responsible for up to 42% of deaths within the first year of life and to make a significant contribution to the 1% of children of school age with physical handicap and the 0.3% with severe learning difficulties. Study Aim: Assessment of metabolic and nutritional status before and after nutrition education program (NEP). Subjects and Methods: A total number of 30 child (17 girls and 13 boys), of those attending the outpatient clinic of "Dietary Intervention of Inborn errors of Metabolism" at the National Nutrition Institute, Cairo, were selected. They were mainly referred from Children Hospital, Kasr El-Ainy and they were suffering from one of the three amino acid disorders; hyperammonia, aminoacidopathy, and organic acidurias. Sociodemographic data, food frequency pattern, 24-hour recall, morbidity recall, medical history and examination and anthropometric measurements were taken...

Research paper thumbnail of Prevalence of overweight and obesity, and status of chronic non- communicable diseases and some related risk factors among Egyptian adolescents

Obesity is a major threat to children's health today. The prevalence of obesity has been stea... more Obesity is a major threat to children's health today. The prevalence of obesity has been steadily increasing; over the past 25 years, the number of obese children has nearly tripled and is more likely to have risk factors for cardiovascular disease, such as type 2 diabetes high cholesterol or high blood pressure. Research objectives were to study the current prevalence of overweight and obesity among adolescents in Egypt from 2000 to 2008, to estimate the prevalence of glucose disorders, hypertension, lipid profile, and metabolic syndrome, and to investigate some related risk factors among 10 to 18 years old school adolescents. For assessing prevalence rates of overweight and obesity among adolescents, data from reports of other cross-sectional studies carried out by National Nutrition Institute (NNI) (2000 to 2005) and Egypt Demographic and Health Survey (2008) were compared. To estimate the prevalence of glucose disorders, hypertension, lipid profile, and metabolic syndrome, a...

Research paper thumbnail of Diet, Nutrition and Prevention of Type Two Diabetes Among Egyptian Adolescents

Journal of Nutrition Education and Behavior, 2009

Outcome, Measures and Analysis: Content analysis was used to determine recurring trends and theme... more Outcome, Measures and Analysis: Content analysis was used to determine recurring trends and themes from the focus groups and food photographs. Results: Most of the teens' stories revealed heavy reliance on and satisfaction with convenience foods because of their taste, cost, and availability. This was particularly true when eating with friends. Few participants assumed responsibility for making food choices that involved others in the family (e.g. grocery shopping or cooking). They expressed a reasonable understanding of healthy eating and its importance, yet lacked a sense of urgency in prioritizing healthy food choices, perceiving change towards a healthier diet undesirable or difficult. However, two girls in the group ate healthfully and were quite proud to share their value for health with the group. Conclusions and Implications: These results suggest that adolescent-targeted nutrition education alone will not succeed for most youth without also having environmental supports such as accessibility to fresh, healthy, affordable foods, family values around meals, positive school-based food experiences, and less media and marketing on unhealthful food and more on healthful foods. This project was supported by Teachers College and Liberty Program.

Research paper thumbnail of Prevalence of metabolic syndrome and insulin resistance among Egyptian adolescents 10 to 18 years of age

Journal of Clinical Lipidology, 2010

The prevalence and magnitude of childhood obesity are increasing dramatically. To examine the eff... more The prevalence and magnitude of childhood obesity are increasing dramatically. To examine the effect of varying social, demographic, dietary, and activity factors on the prevalence of metabolic syndrome and its relation to insulin resistance, C-reactive protein, and homocysteine levels in a large, representative sample of Egyptian adolescents. Our survey included 4250 adolescents (from 10 to 18 years of age; male subjects comprised 42.5% of participants) from 7 governorates representing Egypt. Baseline measurements included blood pressure, fasting blood glucose, plasma lipids, C-reactive protein, and homocysteine levels. Because the body mass index varies according to age, we standardized the value for age and sex with the use of conversion to percentiles. The overall prevalence of the metabolic syndrome was 7.4% with no sex or area of residence predilection. Results showed that adolescents with the full criteria of metabolic syndrome (ie, three criterion or more) constituted nearly one fourth of those exhibiting high values of different components, except for systolic blood pressure, where they were 42%, and TG, where they were 31%. Family history of obesity and diabetes mellitus increase the odds for metabolic syndrome significantly (1.68 and 1.3, respectively) as well as inactivity. A high level of C-reactive protein was reported among affected adolescents. Homocysteine level did not have an influence. The prevalence of the metabolic syndrome is considerable among obese adolescents. Proinflammatory markers associated with an increased risk of adverse cardiovascular outcomes are already present in these youth.