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Research paper thumbnail of Tolerance, pharmacokinetics and efficacy of once daily amikacin for treatment of Pseudomonas aeruginosa pulmonary exacerbations in cystic fibrosis patients

European Journal of Pediatrics, 1996

Twenty cystic fibrosis patients aged 1.8-22 years (mean + SD: 9.6 + 4.8 years) with Pseudomonas a... more Twenty cystic fibrosis patients aged 1.8-22 years (mean + SD: 9.6 + 4.8 years) with Pseudomonas aeruginosa pulmonary exacerbations were treated with amikacin (AM) (35 mg/kg/day in one daily 30 min infusion) associated with either ceftazidime (200 mg/kg/day in 3 i.v. injections) (n = 19) or imipenem (n = 1) at the same dose. Glomerular and tubular functions (creatinine

Research paper thumbnail of Tolerance, pharmacokinetics and efficacy of once daily amikacin for treatment of Pseudomonas aeruginosa pulmonary exacerbations in cystic fibrosis patients

European Journal of Pediatrics, 1996

Twenty cystic fibrosis patients aged 1.8-22 years (mean + SD: 9.6 + 4.8 years) with Pseudomonas a... more Twenty cystic fibrosis patients aged 1.8-22 years (mean + SD: 9.6 + 4.8 years) with Pseudomonas aeruginosa pulmonary exacerbations were treated with amikacin (AM) (35 mg/kg/day in one daily 30 min infusion) associated with either ceftazidime (200 mg/kg/day in 3 i.v. injections) (n = 19) or imipenem (n = 1) at the same dose. Glomerular and tubular functions (creatinine

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