Dr. Mukta JAIN - Academia.edu (original) (raw)

Papers by Dr. Mukta JAIN

Inroads an International Journal of Jaipur National University, 2012

Green chemistry involves the development of chemical products and synthetic procedures, which are... more Green chemistry involves the development of chemical products and synthetic procedures, which are environment friendly and have reduced health risks with the search for more efficient methods to do chemistry. Its roots stem back ten years from a simple idea to a prominent concept which permeates all areas of modern chemistry. Chemistry is undeniably a very prominent part of our daily lives. Food and drink has been made safe to consume, the development of cosmetics has enabled us to beautify and admire our appearances and the whole area of pharmaceuticals has allowed the development and synthesis of new cures for illnesses and diseases, all as a result of chemistry. However, additional chemical developments also bring new environmental problems and harmful unexpected side effects, which result in the need for ‘greener’ chemical products. Green chemistry looks at pollution prevention on the molecular scale and is an extremely important area of Chemistry due to the importance of Chemistry in our world today and the implications it can how on our environment. The Green Chemistry program supports the invention of more environment friendly chemical processes which reduce or even eliminate the generation of hazardous substances. This program works very closely with the twelve principles of Green Chemistry as shown below:Safer Solvents and AuxiliariesDesign for Energy EfficiencyUse of Renewable FeedstocksReduce DerivativesCatalysisDesign for DegradationReal-time analysis for Pollution PreventionInherently Safer Chemistry for Accident PreventionPreventionAtom EconomyLess HazardousDesigning Safer Chemicals

INROADS- An International Journal of Jaipur National University, 2013

Ten brands of ready-to-drink beverages “soft-drinks” were analysed for pH, sucrose, phosphate, gl... more Ten brands of ready-to-drink beverages “soft-drinks” were analysed for pH, sucrose, phosphate, glucose, fructose, and caffeine contents in soft drinks by using standard biochemical procedures. The soft drinks included ‘coca-cola’ popularly referred to as “coke”, “pepsi”, “mirinda”, “fanta”, “sprite”, “mountain dew”, “7up”, “limca”, “maaza”. The result shows that the pH of the soft drinks ranged from 2.46 in pepsi to 3.72 in maaza. Most of the soft drinks have alcohol and aldehyde as the flavouring agents. The concentration of sugar was tested in different cold drinks by comparing the density of different sugar solutions, which are used as sweetener agents in soft drinks. Test of corrosiveness in soft drinks explain the effect of soft drinks on the tooth enamel by studying the effect of cold drinks on a tarnished penny or coin, soft drinks remove the tarnish from the penny; and the darker sodas tarnish off the penny faster than the lighter sodas. The amount of ascorbic acid and benzoic acid is determined by using the titrimetric method and when these acids are used they inhibit the growth of yeast in soft drinks. In the process, it was discerned that the amount of Benzoic acid was generally low in fanta (29.75 mg/ounce) and highest in mountain dew (55.65 mg/ounce). Soft drinks also contain vitamin ‘C’; a low amount of vitamin ‘C’ is present in limca and the soft drinks having the highest content of vitamin C are coca cola and pepsi. The caffeine content in soft drinks was also analysed by UV spectroscopy. Only pepsi, cola, mountain dew and thums up contain caffeine. In other samples, the presence of caffeine or absorbance under the UV spectrometer was not detected.

Phosphorus, Sulfur, and Silicon and the Related Elements, 2004

A facile synthesis and studies on the stereochemistry and biochemical aspects of some organosilic... more A facile synthesis and studies on the stereochemistry and biochemical aspects of some organosilicon(IV), organotin(IV), and manganese(II) complexes derived from imine having N∩N∩O donor system is re-ported. The imine was prepared by the condensation of ...

Metal-Based Drugs, 2002

Some manganese(II) complexes derived from different sulphadrugs and heterocyclic ketones have bee... more Some manganese(II) complexes derived from different sulphadrugs and heterocyclic ketones have been prepared. These complexes have been characterized on the basis of elemental analyses, molecular weight determinations, conductivity measurements, infrared, ESR and magnetic measurements. The spectral data suggest that the ligands act in a monobasic, bidentate manner coordinating through nitrogen atom. A high spin tetrahedral geometry around this metal has been proposed on the basis of magnetic and spectral studies. The isolated products are coloured solids, soluble in DMSO, DMF and MeOH. All the complexes are monomeric in nature as indicated by their molecular weight determinations and conductivity measurements in dry DMF show them to be non-electrolytes. All the ligands and their corresponding complexes have been screened for their fungicidal, bactericidal and nematicidal activities.

Main Group Metal Chemistry, 2003

Organosilicon(IV) derivatives of the types R 2 SiCI(L), R 2 Si(L) 2 and R 3 Si(L) (where, R=pheny... more Organosilicon(IV) derivatives of the types R 2 SiCI(L), R 2 Si(L) 2 and R 3 Si(L) (where, R=phenyl or methyl, L=sulphonamide-imine ligand) have been synthesized and characterized by elemental analyses, IR, 1 H, and 29 Si NMR spectroscopy. These data support the binding of nitrogen to silicon(IV) in R 2 SiCI(L) and R 3 Si(L) complexes with a trigonal bipyramidal geometry. However, R 2 Si(L) 2 type of complexes possess an octahedral geometry. The results of antimicrobial effects of some representative complexes on different species of pathogenic fungi and bacteria have also been recorded and discussed. All the complexes are monomeric in nature as indicated by their molecular weight determinations and conductivity measurements in dry DMF show them to be non-electrolytes. The ligand and its corresponding complexes have also been tested for their nematicidal activity and the findings have been discussed in the present paper.

Main Group Metal Chemistry, 2001

Several new penta-coordinated triorganosilicon(IV) complexes derived from biologically active ben... more Several new penta-coordinated triorganosilicon(IV) complexes derived from biologically active benzothiazolines, 2-(2-furyl)benzothiazoline, 2-(2-pyridyl)benzothiazoline and 2-(2-thienyl)benzothiazoline have been prepared. The newly synthesized complexes of the type, R 3 Si(Bzt) (where R=Me or Ph and where Bzt represents the benzothiazolmate moiety) have been characterized by elemental analyses, molecular weight determinations and conductivity measurements. A probable trigonal bipyramidal structure for the resulting derivatives has been proposed on the basis of electronic, IR, Ή, 13 C NMR and 29 Si NMR spectral studies. Some selected benzothiazolines and their corresponding triorganosilicon(IV) complexes have also been screened against a number of microbes and their sterilizing power in male mice has been tested. An attempt has been made to correlate the structural aspects of the molecules with their biological activity.

Main Group Metal Chemistry, 2006

The penta-and hexa-coordinated, tirgonal bipyramidal and octahedral complexes of organotin(IV) ha... more The penta-and hexa-coordinated, tirgonal bipyramidal and octahedral complexes of organotin(IV) have been synthesized. The imine and its tin complexes were also tested in vitro against fungi: Aspergillus niger, Macrophomina phaseolina, Fusarium oxysporum and Alternaria alternata; bacteria: Escherichia coli(-), Klebsiella aerogenous(-), Pseudomonas cepacicola(-) and Staphylococcus aureus(+)•, nematode: Meloidogyne incognita; and insect: Trogoderma granarium to assess their antimicrobial properties. All the complexes have been shown to have high toxicity at very low concentrations, against a number of microorganisms. The complexes were synthesized by the reactions of a bidentate imine, 4-(2'-furyl ethanimino)-N-(2'-pyridyl)benzene sulphonamide, with Ph 3 SnCl, Ph 2 SnCl 2 and Me 2 SnCl 2. The resulting new complexes have been characterized by elemental analyses, molecular weight determinations, conductivity measurements and infrared, U.V., 'H NMR, ,3 C NMR and U9 Sn NMR spectral data. The IR and 'H NMR spectral data suggest that the imine acts in a monofunctional bidentate manner coordinating through the nitrogen atom. The results in detail are presented in this paper.

Heterocyclic Communications, 2004

The synthetic, spectroscopic and biological studies of some heterocyclic complexes derived from 3... more The synthetic, spectroscopic and biological studies of some heterocyclic complexes derived from 3,8-dimethyl-4,6-diazadecane-3,7-diene-2,9-dione and 3,9-dimethyl-4,8-diazaundecane-3,8-diene-2,10dione and platinum(II) chloride with various type of diamines (1,2-phenylenediamine, naphthalene-1,8diamine,2,6-diaminopyridine or 2,2'-diaminodiethyl amine) have been carried out. These complexes have been characterized on the basis of elemental analysis, molecular weight determinations and spectral studies including IR, 'H NMR, mass and electronic spectra. The resulting coloured products are electrolytic in nature. On the basis of above studies and X-n:y diffraction studies square planar geometry has been proposed for the resulting complexes. The possibility of potential uses of these complexes as fungicides and bactericides have also been explored.

Heterocyclic Communications, 2003

... 126-128°C (11.63) (8.89) (6.79) (472.39) [Mn(2-Ac-F-Sp)2] Light yellow 86 7.41 11.39 8.61 698... more ... 126-128°C (11.63) (8.89) (6.79) (472.39) [Mn(2-Ac-F-Sp)2] Light yellow 86 7.41 11.39 8.61 698.43 136-138°C (7.47) (11.42) (8.72) (735.71) ... 105 (1979). 2. Nighat Fahmi, SCS JadonandR.V. Singh, Phosphorus, Sulfur and Silicon, 81, 133 (1993). ...

Applied Organometallic Chemistry, 2004

ABSTRACT

Applied Organometallic Chemistry, 2005

ABSTRACT Microwave-assisted synthesis and spectroscopic studies of dimethyl-, diphenyl- and triph... more ABSTRACT Microwave-assisted synthesis and spectroscopic studies of dimethyl-, diphenyl- and triphenyl-silicon(IV) chelates derived from the reactions of organochlorosilanes with the sodium salt of a biologically active nitrogen donor ligand N∩NH are described. The resulting products have been isolated and characterized by elemental analyses, molecular weight determinations and conductance measurements. On the basis of electronic, infrared, 1H, 13C and 29Si NMR spectral studies, trigonal bipyramidal and octahedral geometries have been suggested for the resulting complexes. The biological activity of the ligand and its corresponding complexes has been examined with regard to antifungal and antibacterial activity against pathogenic fungi and bacteria, and the results are quite encouraging. All the compounds have also been found to act as nematicides and insecticides, by reducing the number of nematodes (Meloidogyne incognita) and insects (Trogoderma granarium). Copyright © 2005 John Wiley & Sons, Ltd.

Applied Organometallic Chemistry, 2003

ABSTRACT

Applied Organometallic Chemistry, 2004

... biologically active sulfonamide imine ligand Mukta Jain1, Sunita Maanju2 and RV Singh2* 1Depa... more ... biologically active sulfonamide imine ligand Mukta Jain1, Sunita Maanju2 and RV Singh2* 1Department of Chemistry, Seth GB Podar College, Nawalgarh, Jhunjhunu, Rajasthan, India 2Department of Chemistry, University of Rajasthan, Jaipur 302004, India ...

Bioinorganic Chemistry and Applications, 2006

The organosilicon derivatives of2-[1-(2-furayl)ethyledene]sulphathiazole with organosilicon chlor... more The organosilicon derivatives of2-[1-(2-furayl)ethyledene]sulphathiazole with organosilicon chlorides have been synthesised and characterized on the basis of analytical, conductance, and spectroscopic techniques. Probable trigonal bipyramidal and octahedral structures for the resulting derivatives have been proposed on the basis of electronic, IR,1H,13CNMR, and29SiNMR spectral studies. In the search for better fungicides, bactericides, nematicides, and insecticides studies were conducted to assess the growth-inhibiting potential of the synthesized complexes against various pathogenic fungal, bacterial strains, root-knot nematodeMeloidogyne incognita, and insectTrogoderma granariumThese studies demonstrate that the concentrations reached levels which are sufficient to inhibit and kill the pathogens, nematode, and insect.

Inroads an International Journal of Jaipur National University, 2012

Green chemistry involves the development of chemical products and synthetic procedures, which are... more Green chemistry involves the development of chemical products and synthetic procedures, which are environment friendly and have reduced health risks with the search for more efficient methods to do chemistry. Its roots stem back ten years from a simple idea to a prominent concept which permeates all areas of modern chemistry. Chemistry is undeniably a very prominent part of our daily lives. Food and drink has been made safe to consume, the development of cosmetics has enabled us to beautify and admire our appearances and the whole area of pharmaceuticals has allowed the development and synthesis of new cures for illnesses and diseases, all as a result of chemistry. However, additional chemical developments also bring new environmental problems and harmful unexpected side effects, which result in the need for ‘greener’ chemical products. Green chemistry looks at pollution prevention on the molecular scale and is an extremely important area of Chemistry due to the importance of Chemistry in our world today and the implications it can how on our environment. The Green Chemistry program supports the invention of more environment friendly chemical processes which reduce or even eliminate the generation of hazardous substances. This program works very closely with the twelve principles of Green Chemistry as shown below:Safer Solvents and AuxiliariesDesign for Energy EfficiencyUse of Renewable FeedstocksReduce DerivativesCatalysisDesign for DegradationReal-time analysis for Pollution PreventionInherently Safer Chemistry for Accident PreventionPreventionAtom EconomyLess HazardousDesigning Safer Chemicals

INROADS- An International Journal of Jaipur National University, 2013

Ten brands of ready-to-drink beverages “soft-drinks” were analysed for pH, sucrose, phosphate, gl... more Ten brands of ready-to-drink beverages “soft-drinks” were analysed for pH, sucrose, phosphate, glucose, fructose, and caffeine contents in soft drinks by using standard biochemical procedures. The soft drinks included ‘coca-cola’ popularly referred to as “coke”, “pepsi”, “mirinda”, “fanta”, “sprite”, “mountain dew”, “7up”, “limca”, “maaza”. The result shows that the pH of the soft drinks ranged from 2.46 in pepsi to 3.72 in maaza. Most of the soft drinks have alcohol and aldehyde as the flavouring agents. The concentration of sugar was tested in different cold drinks by comparing the density of different sugar solutions, which are used as sweetener agents in soft drinks. Test of corrosiveness in soft drinks explain the effect of soft drinks on the tooth enamel by studying the effect of cold drinks on a tarnished penny or coin, soft drinks remove the tarnish from the penny; and the darker sodas tarnish off the penny faster than the lighter sodas. The amount of ascorbic acid and benzoic acid is determined by using the titrimetric method and when these acids are used they inhibit the growth of yeast in soft drinks. In the process, it was discerned that the amount of Benzoic acid was generally low in fanta (29.75 mg/ounce) and highest in mountain dew (55.65 mg/ounce). Soft drinks also contain vitamin ‘C’; a low amount of vitamin ‘C’ is present in limca and the soft drinks having the highest content of vitamin C are coca cola and pepsi. The caffeine content in soft drinks was also analysed by UV spectroscopy. Only pepsi, cola, mountain dew and thums up contain caffeine. In other samples, the presence of caffeine or absorbance under the UV spectrometer was not detected.

Phosphorus, Sulfur, and Silicon and the Related Elements, 2004

A facile synthesis and studies on the stereochemistry and biochemical aspects of some organosilic... more A facile synthesis and studies on the stereochemistry and biochemical aspects of some organosilicon(IV), organotin(IV), and manganese(II) complexes derived from imine having N∩N∩O donor system is re-ported. The imine was prepared by the condensation of ...

Metal-Based Drugs, 2002

Some manganese(II) complexes derived from different sulphadrugs and heterocyclic ketones have bee... more Some manganese(II) complexes derived from different sulphadrugs and heterocyclic ketones have been prepared. These complexes have been characterized on the basis of elemental analyses, molecular weight determinations, conductivity measurements, infrared, ESR and magnetic measurements. The spectral data suggest that the ligands act in a monobasic, bidentate manner coordinating through nitrogen atom. A high spin tetrahedral geometry around this metal has been proposed on the basis of magnetic and spectral studies. The isolated products are coloured solids, soluble in DMSO, DMF and MeOH. All the complexes are monomeric in nature as indicated by their molecular weight determinations and conductivity measurements in dry DMF show them to be non-electrolytes. All the ligands and their corresponding complexes have been screened for their fungicidal, bactericidal and nematicidal activities.

Main Group Metal Chemistry, 2003

Organosilicon(IV) derivatives of the types R 2 SiCI(L), R 2 Si(L) 2 and R 3 Si(L) (where, R=pheny... more Organosilicon(IV) derivatives of the types R 2 SiCI(L), R 2 Si(L) 2 and R 3 Si(L) (where, R=phenyl or methyl, L=sulphonamide-imine ligand) have been synthesized and characterized by elemental analyses, IR, 1 H, and 29 Si NMR spectroscopy. These data support the binding of nitrogen to silicon(IV) in R 2 SiCI(L) and R 3 Si(L) complexes with a trigonal bipyramidal geometry. However, R 2 Si(L) 2 type of complexes possess an octahedral geometry. The results of antimicrobial effects of some representative complexes on different species of pathogenic fungi and bacteria have also been recorded and discussed. All the complexes are monomeric in nature as indicated by their molecular weight determinations and conductivity measurements in dry DMF show them to be non-electrolytes. The ligand and its corresponding complexes have also been tested for their nematicidal activity and the findings have been discussed in the present paper.

Main Group Metal Chemistry, 2001

Several new penta-coordinated triorganosilicon(IV) complexes derived from biologically active ben... more Several new penta-coordinated triorganosilicon(IV) complexes derived from biologically active benzothiazolines, 2-(2-furyl)benzothiazoline, 2-(2-pyridyl)benzothiazoline and 2-(2-thienyl)benzothiazoline have been prepared. The newly synthesized complexes of the type, R 3 Si(Bzt) (where R=Me or Ph and where Bzt represents the benzothiazolmate moiety) have been characterized by elemental analyses, molecular weight determinations and conductivity measurements. A probable trigonal bipyramidal structure for the resulting derivatives has been proposed on the basis of electronic, IR, Ή, 13 C NMR and 29 Si NMR spectral studies. Some selected benzothiazolines and their corresponding triorganosilicon(IV) complexes have also been screened against a number of microbes and their sterilizing power in male mice has been tested. An attempt has been made to correlate the structural aspects of the molecules with their biological activity.

Main Group Metal Chemistry, 2006

The penta-and hexa-coordinated, tirgonal bipyramidal and octahedral complexes of organotin(IV) ha... more The penta-and hexa-coordinated, tirgonal bipyramidal and octahedral complexes of organotin(IV) have been synthesized. The imine and its tin complexes were also tested in vitro against fungi: Aspergillus niger, Macrophomina phaseolina, Fusarium oxysporum and Alternaria alternata; bacteria: Escherichia coli(-), Klebsiella aerogenous(-), Pseudomonas cepacicola(-) and Staphylococcus aureus(+)•, nematode: Meloidogyne incognita; and insect: Trogoderma granarium to assess their antimicrobial properties. All the complexes have been shown to have high toxicity at very low concentrations, against a number of microorganisms. The complexes were synthesized by the reactions of a bidentate imine, 4-(2'-furyl ethanimino)-N-(2'-pyridyl)benzene sulphonamide, with Ph 3 SnCl, Ph 2 SnCl 2 and Me 2 SnCl 2. The resulting new complexes have been characterized by elemental analyses, molecular weight determinations, conductivity measurements and infrared, U.V., 'H NMR, ,3 C NMR and U9 Sn NMR spectral data. The IR and 'H NMR spectral data suggest that the imine acts in a monofunctional bidentate manner coordinating through the nitrogen atom. The results in detail are presented in this paper.

Heterocyclic Communications, 2004

The synthetic, spectroscopic and biological studies of some heterocyclic complexes derived from 3... more The synthetic, spectroscopic and biological studies of some heterocyclic complexes derived from 3,8-dimethyl-4,6-diazadecane-3,7-diene-2,9-dione and 3,9-dimethyl-4,8-diazaundecane-3,8-diene-2,10dione and platinum(II) chloride with various type of diamines (1,2-phenylenediamine, naphthalene-1,8diamine,2,6-diaminopyridine or 2,2'-diaminodiethyl amine) have been carried out. These complexes have been characterized on the basis of elemental analysis, molecular weight determinations and spectral studies including IR, 'H NMR, mass and electronic spectra. The resulting coloured products are electrolytic in nature. On the basis of above studies and X-n:y diffraction studies square planar geometry has been proposed for the resulting complexes. The possibility of potential uses of these complexes as fungicides and bactericides have also been explored.

Heterocyclic Communications, 2003

... 126-128°C (11.63) (8.89) (6.79) (472.39) [Mn(2-Ac-F-Sp)2] Light yellow 86 7.41 11.39 8.61 698... more ... 126-128°C (11.63) (8.89) (6.79) (472.39) [Mn(2-Ac-F-Sp)2] Light yellow 86 7.41 11.39 8.61 698.43 136-138°C (7.47) (11.42) (8.72) (735.71) ... 105 (1979). 2. Nighat Fahmi, SCS JadonandR.V. Singh, Phosphorus, Sulfur and Silicon, 81, 133 (1993). ...

Applied Organometallic Chemistry, 2004

ABSTRACT

Applied Organometallic Chemistry, 2005

ABSTRACT Microwave-assisted synthesis and spectroscopic studies of dimethyl-, diphenyl- and triph... more ABSTRACT Microwave-assisted synthesis and spectroscopic studies of dimethyl-, diphenyl- and triphenyl-silicon(IV) chelates derived from the reactions of organochlorosilanes with the sodium salt of a biologically active nitrogen donor ligand N∩NH are described. The resulting products have been isolated and characterized by elemental analyses, molecular weight determinations and conductance measurements. On the basis of electronic, infrared, 1H, 13C and 29Si NMR spectral studies, trigonal bipyramidal and octahedral geometries have been suggested for the resulting complexes. The biological activity of the ligand and its corresponding complexes has been examined with regard to antifungal and antibacterial activity against pathogenic fungi and bacteria, and the results are quite encouraging. All the compounds have also been found to act as nematicides and insecticides, by reducing the number of nematodes (Meloidogyne incognita) and insects (Trogoderma granarium). Copyright © 2005 John Wiley & Sons, Ltd.

Applied Organometallic Chemistry, 2003

ABSTRACT

Applied Organometallic Chemistry, 2004

... biologically active sulfonamide imine ligand Mukta Jain1, Sunita Maanju2 and RV Singh2* 1Depa... more ... biologically active sulfonamide imine ligand Mukta Jain1, Sunita Maanju2 and RV Singh2* 1Department of Chemistry, Seth GB Podar College, Nawalgarh, Jhunjhunu, Rajasthan, India 2Department of Chemistry, University of Rajasthan, Jaipur 302004, India ...

Bioinorganic Chemistry and Applications, 2006

The organosilicon derivatives of2-[1-(2-furayl)ethyledene]sulphathiazole with organosilicon chlor... more The organosilicon derivatives of2-[1-(2-furayl)ethyledene]sulphathiazole with organosilicon chlorides have been synthesised and characterized on the basis of analytical, conductance, and spectroscopic techniques. Probable trigonal bipyramidal and octahedral structures for the resulting derivatives have been proposed on the basis of electronic, IR,1H,13CNMR, and29SiNMR spectral studies. In the search for better fungicides, bactericides, nematicides, and insecticides studies were conducted to assess the growth-inhibiting potential of the synthesized complexes against various pathogenic fungal, bacterial strains, root-knot nematodeMeloidogyne incognita, and insectTrogoderma granariumThese studies demonstrate that the concentrations reached levels which are sufficient to inhibit and kill the pathogens, nematode, and insect.