Dr Raghuveer Choudhary - Academia.edu (original) (raw)

Papers by Dr Raghuveer Choudhary

Journal of Mid-life Health

Objective: This study was conducted to assess lean body mass, body fat percentage, and handgrip s... more Objective: This study was conducted to assess lean body mass, body fat percentage, and handgrip strength in the prediction of bone mineral density (BMD) in postmenopausal women. Materials and Methods: This cross-sectional study included 102 postmenopausal women aged between 45 and 80 years (mean age 58) who were screened for osteoporosis using a dual-energy X-ray absorptiometry scan at the lumbar spine. The lean body mass, body fat percentage, and handgrip strength were calculated. Results: The lean body mass, body fat percentage, and handgrip strength were having a positive association (correlation coefficient: 0.48, 0.29, and 0.3, respectively) with BMD. Conclusion: Lean body mass, body fat percentage, and handgrip strength can detect early loss of BMD in postmenopausal women leading to early screening for osteoporosis resulting in early interventions minimizing BMD loss over a much longer period after menopause.

National Journal of Physiology, Pharmacy and Pharmacology, 2022

Background: Pulmonary function parameters can be altered with the change in body position. Theref... more Background: Pulmonary function parameters can be altered with the change in body position. Therefore, physiological basis behind such consequent influence is essential to be understood. Pulmonary function tests are generally conducted in the erect sitting posture as it is more feasible and comfortable. However, bedridden patients are unable to do so and only few studies are found on recumbent postures. Thus, to comfort such patients in breathing, need arises to meet this requisite investigation to conclude the best recumbent body posture. Aim and Objectives: To compare and assess forced vital capacity (FVC), forced expiratory volume in 1 second (FEV 1), FEV 1 /FVC ratio, forced expiratory flow of during 25-75% expiration (FEF 25-75% , and peak expiratory flow rate (PEF) in the Supine, Crook-lying and Fowler's position. Materials and Methods: The present research was carried out on 128 healthy adults to measure FVC, FEV 1 , FEV 1 /FVC ratio, FEF 25-75% and PEF using a computer-based spirometer in the Supine, Crook-lying and Fowler's position. One-way Analysis of Variance with Tukey HSD post-hoc test was utilized between each body postures by evaluation of their mean values. Results: This study consisted of 128 subjects (males 57, females 71) with mean age of 21.62 ± 1.75 years, mean weight 59.71 ± 9.97 kg, mean height 164.68 ± 9.30 cm and Body mass index 21.91 ± 2.38 kg/m 2. Fowler's posture showed significantly (P < 0.05) higher value in all spirometric parameters as compared to other two postures. Outcome of the study showed all spirometric parameters value-greater in the Fowler's posture than that of Supine or Crook-lying posture. Conclusion: The implication of this research is that it will meet the need of selection of the most suitable substitute posture for better pulmonary functioning in bedridden people.

A variety of laboratory tests are used in the evaluation of hepatic patients. Serum cholinesteras... more A variety of laboratory tests are used in the evaluation of hepatic patients. Serum cholinesterase is reduced in liver dysfunction in contrast to other enzymes. Liver is the main source of Pseudocholinesterase. A comparative study of Pseudocholinesterase along with other relevant liver function test parameters were investigated in different hepatic disorders in present study. The present study was designed to compared the levels of the serum cholinestearse with convectional liver functions tests to determine whether the single estimation of serum CHE level can help to distiniguish hepatic disease from nonhepatic diseases. Total 100 subjects of both sex with age ranged from 15 to 65 years were selected for the study. All the subjects were then divided into two groups, 50 hepatic diseases subjects and 50 nonhepatic diseases subjects. Then liver function tests were evaluated by estimating comprising total billirubin, direct billirubin, indirect billirubin total plasma protein, albumin,...

International Journal of Physiology, 2021

Background: The role of sympathovagal imbalance (SVI) and CV risk in pregnancy-induced hypertensi... more Background: The role of sympathovagal imbalance (SVI) and CV risk in pregnancy-induced hypertension (PIH) has been reported, and their association during early trimesters of gestation in PIH has not been studied. Therefore, in the present study, we have investigated the maternal cardiovascular parameters and frequency domain indices of Heart rate variability (HRV) between normal pregnant women and women with risk factors for PIH in their 1 st trimester of gestation. Methods: Two hundred twenty subjects each (220 of normotensive pregnant women i.e., control group and 220 of pregnant women with risk factor for PIH i.e., study group) of 1 st trimester of gestation were recruited from the obstetrics & gynecology department of Umaid hospital, associated with Dr. S. N. Medical College, Jodhpur, Rajasthan. Physical examination was done and anthropometric measurement like height & weight were taken. The collected data was statistically analyzed using HRV analysis software. Results: Significant difference in body mass index was observed between the two groups. Systolic blood pressure, Diastolic blood pressure, Pulse pressure, Rate pressure product and Mean arterial pressure of study group was significantly higher than control group. Values of LF and LF/HF ratio components of frequency domain analysis of HRV were significantly increased but HF component is non significantly decrease in 1 st trimester of the pregnant women with risk factor for PIH than normal pregnant women. Conclusion: The present study indicates that the cardiovascular parameters in 1 st trimester of pregnant women with risk factor for PIH were increased highly significantly than the normal pregnant women. The highly significant (HS) (p<0.000) increase in the LF (nu) & LF/HF ratio and non significant (NS) (p<0.552) decrease in HF (nu) of pregnant women with risk factors for PIH was observed than normal pregnant women this indicate that sympathetic tone was increased in 1 st trimester of pregnant women with risk factor for PIH. Vagal withdrawal and sympathetic exaggeration may be the possible cause of PIH in pregnant women with its risk factors.

Background: Abdominal adiposity is suggested to be more closely associated with CVD risk and has ... more Background: Abdominal adiposity is suggested to be more closely associated with CVD risk and has been highlighted as a growing problem particularly in countries of Asia-Pacific region where individuals may exhibit a relatively normal BMI (<25 kg/m2) but have a disproportionately large waist circumference. Our objective is to compare body mass index(BMI), waist circumference (WC), waist hip ratio (WHR), waist stature ratio(WSR) and Body Fat% (BF%) as indices of obesity and assess the respective association with Resting Heart Rate (RHR). Method: A cross sectional descriptive study was made on 200 individual. Anthropometric measure was obtained and indices of general obesity BMI and indices of visceral obesity WC, WHR, WSR, BF %, Fat Free Mass (FFM) were calculated. RHR in standing and supine position were obtained by ECG. Pearson's correlation (r) between obesity indices and resting heart rate in normal weight and obese were calculated. Result: Multiple regression method was ap...

National Journal of Physiology, Pharmacy and Pharmacology, 2021

Background: The recent years have witnessed a surge in the incidence of stroke cases worldwide. S... more Background: The recent years have witnessed a surge in the incidence of stroke cases worldwide. Stroke is the most common neurological emergency. It is the second most known common cause of death and one among the major cause of disability worldwide. Aim and Objectives: The main aim of this study is to analyze the major associated risk factors in stroke and assess the awareness among the survivors for the same. Material and Methods: This was a prospective, cross-sectional, observational study, conducted among 100 patients in both sexes in the age group of 25–75 years admitted in Neurology and General Medicine ward at Mathura Das Mathur Hospital, Dr. Sampurnanand Medical College, Jodhpur. The information was collected by previously designed questionnaire. The data were collected and analyzed using appropriate statistical tests. Results: In our study, 100 patients with stroke were included. Out of these 100 patients, 72% of patients suffered an ischemic stroke and 28% a hemorrhagic st...

Bangladesh Journal of Physiology and Pharmacology, 2015

It is an established fact that life-style related behavioral factors are mainly responsible for c... more It is an established fact that life-style related behavioral factors are mainly responsible for cardiovascular diseases. Doctors are playing very important role in imparting knowledge to the society as to how to stay away from diseases by adopting preventive measures. We studied the prevalence of life-style related risk behavior in medical students and to determine the effect of these factors on blood pressure. The study was conducted on 249 medical students, from which 182 were boys and 67 were girls of age group 16-29 years. In a random cross-sectional survey of medical students were interviewed for anthropometric measurements, BMI, dietary habits, physical activity and cardiovascular parameters. Cardiovascular risk factors in boys of medical college are more than girls. Out of 182 boys studied 48 [26.37%] were having their blood pressure values higher than 130/90 mm Hg. because of their faulty living/eating habits. Junk food, cola, alcohol and smoking is on rising trend with pred...

Pulmonary function tests are used to measure baseline status of respiratory function, to monitor ... more Pulmonary function tests are used to measure baseline status of respiratory function, to monitor treatment and to estimate prognosis. The present study was aimed to determine pulmonary function tests values and to compare the different parameters like FVC, FEV1, FEV1/FVC, FEF25-75%, PEFR and MVV in healthy male and female subjects of western Rajasthan. The study included 150 subjects of age range from 20 to 75 years above. Out of these 150 subjects 75 were males and 75 were females. Pulmonary function tests were done with the help of computerized spirometer. Different parameters like FVC, FEV1, FEV1/FVC, FEF25-75%, PEFR and MVV were recorded. The results showed that all parameter were higher in males, when compared with females. Statistical significance was obtained by using ttest (P<0.001). It is probably a result of increase strength of expiratory muscles and increase chest wall compliance in males than females.

Background: Neuropathic pain syndrome is a frequently occurring, disabling disease. Many anticanc... more Background: Neuropathic pain syndrome is a frequently occurring, disabling disease. Many anticancer drugs which are used to treat solid tumors cause neuropathic pain as their dose limiting side effect. Current treatment options are still relatively poor. Objective: The present study was designed to compare the effect of gabapentin, topiramate, levetiracetam and zonisamidefor treatment of neuropathic pain induced by anticancer drug(vincristine) in albinorats using thermal method. Materials and Methods: Neuropathic pain was induced by injecting vincristine (100µg/kg) intraperitoneally daily for 14 days in rats. Behavioural testing for thermal hyperalgesia was assessed 24 hours after each injection by the hotplat method. After 14 days rats were divided into five groups of six animals each. Group I was treated with distilled water as control group, group II was treated with oral gabapentin (60 mg/kg), group III received oral topiramate (40 mg/kg), group IV was treated with oral levetira...

Background: A lot of age-specific variations in Peak Expiratory Flow Rate (PEFR) are expected in ... more Background: A lot of age-specific variations in Peak Expiratory Flow Rate (PEFR) are expected in paediatrics age group compared to adults. Therefore availability of normal values for different age group is absolutely essential for logical interpretation of PEFR. Only few studies are available on ventilator functions for children of Western Rajasthan (a desert area) 7–14 years of Age. Method: One hundred and eighty-eight apparently healthy school children (112 Male, 76 Female) from age group 7–14 years were included in the study. PEFR was measured in L/min with a standard Wright Peak Flow Meter. Result: Positive correlation was seen between age, height, weight, Body surface area, and PEFR. The regression equations for PEFR were determined for boys and girls separately. The prediction equation for PEFR based on Weight was PEFR=71.519+weight×4.202 (for boys) PEFR=115.081+weight×1.406 (for girls). Predicted formulas obtained by regression equation for Age were: PEFR=27.442+Age×17.289 (f...

The objective of the study was to determine the relationship between ABO blood groups and diabete... more The objective of the study was to determine the relationship between ABO blood groups and diabetes mellitus in the population of Jodhpur city of Rajasthan State (India). The present cross sectional study analyzes ABO blood group among 400 subjects of every age taken randomly from the local population of Jodhpur city in the duration of January to may 2013. Out of 400subjects, 200 were normal healthy (97 male and 103 female) students of Dr. S.N. Medical College, Jodhpur and remaining 200 were DM patients (53 type 1(Insulin dependent) &147 Type 2 (Non insulin dependent)) attending the OPD of MDM & Umaid Hospital, Jodhpur. ABO blood groups of all subjects were determined by slide agglutination method. Data were analyzed by 'one sample chi square test'. The results obtained in this study indicated that there was no significant difference in the frequency of ABO blood groups in Controls and Diabetic Patients of both Type I & II in all studied subjects (males, females and subjects ...

The present study is undertaken to estimate the plasma homocysteine level in cerebrovascular acci... more The present study is undertaken to estimate the plasma homocysteine level in cerebrovascular accident cases with the aim to search for the prevalence of elevated homocysteine level in cerebrovascular accident (Stroke) among patient of western Rajasthan. This study was conducted on 50 stroke patient (Case group) and 50 normal subjects (Control group)of both sex and aged between 30 yrs-75 yrs. Both groups were subjected to routine investigations like Blood sugar, Lipid profile, and Plasma Hcy concentration. A detail medical history was obtained. All study groups were subjected to investigation including neurological examination, blood examination, renal function, urine examination, chest X ray & ECG, and CT/MRI. Plasma Hcy concentration was measured by Chemiluminescent Magnetic Immunoassay (CMIA), using plasma on the ARCHITECT I System from standard laboratory in all the stroke patients of case group. Similar investigations were done for control group except CT Scan/MRI. In results th...

With regular cohabitation without any protection if women do not conceive for at least a period o... more With regular cohabitation without any protection if women do not conceive for at least a period of one year is labelled as infertility. It is based on the observation that most of the normal couples achieve conception within a year of initiation of regular sex. Infertility affects approximately 15% of all couples trying to conceive. It’s a major clinical problem, affecting people medically and psychologically. Male factor infertility is the major cause in roughly half of the cases, and no identifiable cause can be found in over 25% of infertile males. Out of many causes of male infertility Oxidative stress (OS) has been attributed to affect the fertility status and thus, it has been studied extensively in recent years. Excessive production of free radicals or reactive oxygen species (ROS) can damage sperm and ROS has been extensively studied as one of the major mechanism of infertility

Cardiovascular diseases are emerging as one of the leading causes of morbidity and mortality in t... more Cardiovascular diseases are emerging as one of the leading causes of morbidity and mortality in the Indian population. The major risk factors contributing to cardiovascular diseases include hypertension, diabetes mellitus, smoking, hypercholesterolemia and family history of coronary artery disease. Among which hypertension contributes the most. Arterial stiffness, a major contributor of atherosclerosis, has been shown to have positive relationship with systolic hypertension, coronary artery disease, stroke and heart failure. Hence measurement of arterial stiffness seems to be an important tool to assess cardiovascular risk in hypertensive patients. So the present study was undertaken to find out the relationship between arterial stiffness and hypertension in Jodhpur city. 103 subjects with systolic blood pressure >120 mm Hg, were taken, ranging between 25-90 years of age. Anthropometric measures were done manually while all other measures including the parameters of arterial stif...

Scientific studies confirm that it is the evaluation system rather than educational objectives, c... more Scientific studies confirm that it is the evaluation system rather than educational objectives, curriculum or instructional techniques that have the most profound impact on students learning. The present study was done to find out the coverage of different sub-divisions of physiology in written examination and its comparison with the teaching hours devoted to the teaching of each topic. For the analyses of the written question papers, all the questions of the first M.B.B.S examination of Rajasthan University of Health Sciences from 2001 to 2006 were examined and analyzed for content validity. The results of this analysis were then compared with percentage frequency of teaching hours devoted to each topic. Highest percentage frequency of coverage was with cardiovascular system (15.40%) while lowest was for exercise physiology (1.26%). 45% coverage of all the segments was asked from CVS, blood and CNS including special senses. The percentage frequency of classes for these topics was a...

Background: ISH is the most common type of hypertension in people over 60 years of age and increa... more Background: ISH is the most common type of hypertension in people over 60 years of age and increase in SBP being the principal characteristic in this population. Interestingly, data from a number of studies suggest that ISH is also prevalent in adolescents and young adults but findings from previous studies examining this question are inconclusive, so the aim of our study is to know prevalence and determinants of ISH in young healthy individuals. Method: We performed a cross section study on 400 young individuals between 18 to 30 years in western Rajasthan. The participants were then subjected to a set of questionnaire which included socio-demography determinants (age, sex, occupation and annual household income), personal habits (dietary habits, smoking, alcohol consumption), past history and family history of hypertension. They were then subjected to the measurement of height, weight, pulse rate, blood pressure, fasting blood sugar and serum cholesterol level. Result: In our study...

Arterial stiffness and type 2 diabetes Mellitus (T2DM) are associated with increased risk for car... more Arterial stiffness and type 2 diabetes Mellitus (T2DM) are associated with increased risk for cardiovascular disease (CVD) and mortality. By assessing the arterial stiffness in diabetics, the risk of CVD could be quantified in T2DM. Aim of this cross sectional study to assess the association of arterial stiffness and T2DM. 25 normal and 60 atleast 1year history of T2DM males, aged 25 to 65 years of western Rajasthan were examined for arterial stiffness. Anthropometric data such as weight and height were taken to derive Body Mass Index (BMI). Right and left brachial ankle Pulse Wave Velocities (Br Ank PWV) and carotid to femoral Pulse Wave Velocity (cf PWV) were taken as indices of regional and central arterial stiffness respectively. On other hand right and left, brachial and ankle Arterial Stiffness Indexes (ASI) are taken as indices for corresponding local arterial stiffness. These were measured by an automated device Periscope (developed by genesis medical system, Hyderabad) base...

Background: Physical fitness is required not only by athletes for better performance but also by ... more Background: Physical fitness is required not only by athletes for better performance but also by non-athletes for maintenance of physical and mental health. Objective: The aim of the study was to assess the role of aerobic exercise on Haemoglobin and % Saturation of Haemoglobin among untrained and trained subjects. Methods: The present study was conducted in the Department of Physiology, Dr. S.N. Medical College, Jodhpur after ethical approval. Informed written consent was obtained from all the subjects included in the study. In this study total 200 male subjects were included, which were further divided in two groups. Group I: included 100 randomly selected untrained male subjects (medical students) at the beginning of their training period. Group II: It included the same 100 healthy medical students, as in group I, but after their training period of 3 months duration. Group III: 100 randomly selected male Athletes participating in city/district/state competition constituted the tr...

Objectives: This study was done to establish the normal values of various haematological paramete... more Objectives: This study was done to establish the normal values of various haematological parameters for healthy adult of Western Rajasthan (males and females) and to compare these values with those obtained for other population in both India and tropical countries. Methods: This study was under taken in reference adult Western Rajasthan Population in the area of Jodhpur, India. A total 1000 healthy volunteers whose ages ranged between 20–50 years, were investigated. All laboratory analysis was conducted under standardized conditions atL.N. Memorial Hospital & Research Centre, Jodhpur.Results:In Males, the mean Haemoglobin concentration (Hb) of 14.03 g/dl and Haematocrit (HCT) ratio of 44% were significantly higherthan femalevalue of 12.50 g/dl and 40% respectively. The mean Red Blood Cell (RBC) countof 4.90 x 106/μL in males was also significantly higher than the corresponding value of 4.50 x 106/μL infemales (p<0.05). The value of Mean Corpuscular Volume (MCV) in males (88.12 fL...

Background: The ECG pattern in paediatric population varies with age and sex. The majority of cha... more Background: The ECG pattern in paediatric population varies with age and sex. The majority of changes occur during the first year of life due to changes in cardiac anatomy and haemodynamics soon after birth, as a result of the cessation of placental circulation and establishing cardiopulmonary circulation. Therefore the majority of normal adult values cannot be used in the newborn. Methods: This study was carried out in 200 children, with equal males and females, divided into 5 age groups from 0–14 years. Single chest lead ECG machine with standard setting (10 mm/mV. with a standard paper speed of 25 mm/sec.) was used in the study for recording of ECG. The electrocardiogram was recorded in all 12 leads and carefully interpreted for heart rate, rhythm, intervals and duration for evaluation of developmental, age and sex related changes. Results: The heart rate was increased in first 1–2 month of age and then in the following 6 months it remained stable and then slowly declined after 1...

Journal of Mid-life Health

Objective: This study was conducted to assess lean body mass, body fat percentage, and handgrip s... more Objective: This study was conducted to assess lean body mass, body fat percentage, and handgrip strength in the prediction of bone mineral density (BMD) in postmenopausal women. Materials and Methods: This cross-sectional study included 102 postmenopausal women aged between 45 and 80 years (mean age 58) who were screened for osteoporosis using a dual-energy X-ray absorptiometry scan at the lumbar spine. The lean body mass, body fat percentage, and handgrip strength were calculated. Results: The lean body mass, body fat percentage, and handgrip strength were having a positive association (correlation coefficient: 0.48, 0.29, and 0.3, respectively) with BMD. Conclusion: Lean body mass, body fat percentage, and handgrip strength can detect early loss of BMD in postmenopausal women leading to early screening for osteoporosis resulting in early interventions minimizing BMD loss over a much longer period after menopause.

National Journal of Physiology, Pharmacy and Pharmacology, 2022

Background: Pulmonary function parameters can be altered with the change in body position. Theref... more Background: Pulmonary function parameters can be altered with the change in body position. Therefore, physiological basis behind such consequent influence is essential to be understood. Pulmonary function tests are generally conducted in the erect sitting posture as it is more feasible and comfortable. However, bedridden patients are unable to do so and only few studies are found on recumbent postures. Thus, to comfort such patients in breathing, need arises to meet this requisite investigation to conclude the best recumbent body posture. Aim and Objectives: To compare and assess forced vital capacity (FVC), forced expiratory volume in 1 second (FEV 1), FEV 1 /FVC ratio, forced expiratory flow of during 25-75% expiration (FEF 25-75% , and peak expiratory flow rate (PEF) in the Supine, Crook-lying and Fowler's position. Materials and Methods: The present research was carried out on 128 healthy adults to measure FVC, FEV 1 , FEV 1 /FVC ratio, FEF 25-75% and PEF using a computer-based spirometer in the Supine, Crook-lying and Fowler's position. One-way Analysis of Variance with Tukey HSD post-hoc test was utilized between each body postures by evaluation of their mean values. Results: This study consisted of 128 subjects (males 57, females 71) with mean age of 21.62 ± 1.75 years, mean weight 59.71 ± 9.97 kg, mean height 164.68 ± 9.30 cm and Body mass index 21.91 ± 2.38 kg/m 2. Fowler's posture showed significantly (P < 0.05) higher value in all spirometric parameters as compared to other two postures. Outcome of the study showed all spirometric parameters value-greater in the Fowler's posture than that of Supine or Crook-lying posture. Conclusion: The implication of this research is that it will meet the need of selection of the most suitable substitute posture for better pulmonary functioning in bedridden people.

A variety of laboratory tests are used in the evaluation of hepatic patients. Serum cholinesteras... more A variety of laboratory tests are used in the evaluation of hepatic patients. Serum cholinesterase is reduced in liver dysfunction in contrast to other enzymes. Liver is the main source of Pseudocholinesterase. A comparative study of Pseudocholinesterase along with other relevant liver function test parameters were investigated in different hepatic disorders in present study. The present study was designed to compared the levels of the serum cholinestearse with convectional liver functions tests to determine whether the single estimation of serum CHE level can help to distiniguish hepatic disease from nonhepatic diseases. Total 100 subjects of both sex with age ranged from 15 to 65 years were selected for the study. All the subjects were then divided into two groups, 50 hepatic diseases subjects and 50 nonhepatic diseases subjects. Then liver function tests were evaluated by estimating comprising total billirubin, direct billirubin, indirect billirubin total plasma protein, albumin,...

International Journal of Physiology, 2021

Background: The role of sympathovagal imbalance (SVI) and CV risk in pregnancy-induced hypertensi... more Background: The role of sympathovagal imbalance (SVI) and CV risk in pregnancy-induced hypertension (PIH) has been reported, and their association during early trimesters of gestation in PIH has not been studied. Therefore, in the present study, we have investigated the maternal cardiovascular parameters and frequency domain indices of Heart rate variability (HRV) between normal pregnant women and women with risk factors for PIH in their 1 st trimester of gestation. Methods: Two hundred twenty subjects each (220 of normotensive pregnant women i.e., control group and 220 of pregnant women with risk factor for PIH i.e., study group) of 1 st trimester of gestation were recruited from the obstetrics & gynecology department of Umaid hospital, associated with Dr. S. N. Medical College, Jodhpur, Rajasthan. Physical examination was done and anthropometric measurement like height & weight were taken. The collected data was statistically analyzed using HRV analysis software. Results: Significant difference in body mass index was observed between the two groups. Systolic blood pressure, Diastolic blood pressure, Pulse pressure, Rate pressure product and Mean arterial pressure of study group was significantly higher than control group. Values of LF and LF/HF ratio components of frequency domain analysis of HRV were significantly increased but HF component is non significantly decrease in 1 st trimester of the pregnant women with risk factor for PIH than normal pregnant women. Conclusion: The present study indicates that the cardiovascular parameters in 1 st trimester of pregnant women with risk factor for PIH were increased highly significantly than the normal pregnant women. The highly significant (HS) (p<0.000) increase in the LF (nu) & LF/HF ratio and non significant (NS) (p<0.552) decrease in HF (nu) of pregnant women with risk factors for PIH was observed than normal pregnant women this indicate that sympathetic tone was increased in 1 st trimester of pregnant women with risk factor for PIH. Vagal withdrawal and sympathetic exaggeration may be the possible cause of PIH in pregnant women with its risk factors.

Background: Abdominal adiposity is suggested to be more closely associated with CVD risk and has ... more Background: Abdominal adiposity is suggested to be more closely associated with CVD risk and has been highlighted as a growing problem particularly in countries of Asia-Pacific region where individuals may exhibit a relatively normal BMI (<25 kg/m2) but have a disproportionately large waist circumference. Our objective is to compare body mass index(BMI), waist circumference (WC), waist hip ratio (WHR), waist stature ratio(WSR) and Body Fat% (BF%) as indices of obesity and assess the respective association with Resting Heart Rate (RHR). Method: A cross sectional descriptive study was made on 200 individual. Anthropometric measure was obtained and indices of general obesity BMI and indices of visceral obesity WC, WHR, WSR, BF %, Fat Free Mass (FFM) were calculated. RHR in standing and supine position were obtained by ECG. Pearson's correlation (r) between obesity indices and resting heart rate in normal weight and obese were calculated. Result: Multiple regression method was ap...

National Journal of Physiology, Pharmacy and Pharmacology, 2021

Background: The recent years have witnessed a surge in the incidence of stroke cases worldwide. S... more Background: The recent years have witnessed a surge in the incidence of stroke cases worldwide. Stroke is the most common neurological emergency. It is the second most known common cause of death and one among the major cause of disability worldwide. Aim and Objectives: The main aim of this study is to analyze the major associated risk factors in stroke and assess the awareness among the survivors for the same. Material and Methods: This was a prospective, cross-sectional, observational study, conducted among 100 patients in both sexes in the age group of 25–75 years admitted in Neurology and General Medicine ward at Mathura Das Mathur Hospital, Dr. Sampurnanand Medical College, Jodhpur. The information was collected by previously designed questionnaire. The data were collected and analyzed using appropriate statistical tests. Results: In our study, 100 patients with stroke were included. Out of these 100 patients, 72% of patients suffered an ischemic stroke and 28% a hemorrhagic st...

Bangladesh Journal of Physiology and Pharmacology, 2015

It is an established fact that life-style related behavioral factors are mainly responsible for c... more It is an established fact that life-style related behavioral factors are mainly responsible for cardiovascular diseases. Doctors are playing very important role in imparting knowledge to the society as to how to stay away from diseases by adopting preventive measures. We studied the prevalence of life-style related risk behavior in medical students and to determine the effect of these factors on blood pressure. The study was conducted on 249 medical students, from which 182 were boys and 67 were girls of age group 16-29 years. In a random cross-sectional survey of medical students were interviewed for anthropometric measurements, BMI, dietary habits, physical activity and cardiovascular parameters. Cardiovascular risk factors in boys of medical college are more than girls. Out of 182 boys studied 48 [26.37%] were having their blood pressure values higher than 130/90 mm Hg. because of their faulty living/eating habits. Junk food, cola, alcohol and smoking is on rising trend with pred...

Pulmonary function tests are used to measure baseline status of respiratory function, to monitor ... more Pulmonary function tests are used to measure baseline status of respiratory function, to monitor treatment and to estimate prognosis. The present study was aimed to determine pulmonary function tests values and to compare the different parameters like FVC, FEV1, FEV1/FVC, FEF25-75%, PEFR and MVV in healthy male and female subjects of western Rajasthan. The study included 150 subjects of age range from 20 to 75 years above. Out of these 150 subjects 75 were males and 75 were females. Pulmonary function tests were done with the help of computerized spirometer. Different parameters like FVC, FEV1, FEV1/FVC, FEF25-75%, PEFR and MVV were recorded. The results showed that all parameter were higher in males, when compared with females. Statistical significance was obtained by using ttest (P<0.001). It is probably a result of increase strength of expiratory muscles and increase chest wall compliance in males than females.

Background: Neuropathic pain syndrome is a frequently occurring, disabling disease. Many anticanc... more Background: Neuropathic pain syndrome is a frequently occurring, disabling disease. Many anticancer drugs which are used to treat solid tumors cause neuropathic pain as their dose limiting side effect. Current treatment options are still relatively poor. Objective: The present study was designed to compare the effect of gabapentin, topiramate, levetiracetam and zonisamidefor treatment of neuropathic pain induced by anticancer drug(vincristine) in albinorats using thermal method. Materials and Methods: Neuropathic pain was induced by injecting vincristine (100µg/kg) intraperitoneally daily for 14 days in rats. Behavioural testing for thermal hyperalgesia was assessed 24 hours after each injection by the hotplat method. After 14 days rats were divided into five groups of six animals each. Group I was treated with distilled water as control group, group II was treated with oral gabapentin (60 mg/kg), group III received oral topiramate (40 mg/kg), group IV was treated with oral levetira...

Background: A lot of age-specific variations in Peak Expiratory Flow Rate (PEFR) are expected in ... more Background: A lot of age-specific variations in Peak Expiratory Flow Rate (PEFR) are expected in paediatrics age group compared to adults. Therefore availability of normal values for different age group is absolutely essential for logical interpretation of PEFR. Only few studies are available on ventilator functions for children of Western Rajasthan (a desert area) 7–14 years of Age. Method: One hundred and eighty-eight apparently healthy school children (112 Male, 76 Female) from age group 7–14 years were included in the study. PEFR was measured in L/min with a standard Wright Peak Flow Meter. Result: Positive correlation was seen between age, height, weight, Body surface area, and PEFR. The regression equations for PEFR were determined for boys and girls separately. The prediction equation for PEFR based on Weight was PEFR=71.519+weight×4.202 (for boys) PEFR=115.081+weight×1.406 (for girls). Predicted formulas obtained by regression equation for Age were: PEFR=27.442+Age×17.289 (f...

The objective of the study was to determine the relationship between ABO blood groups and diabete... more The objective of the study was to determine the relationship between ABO blood groups and diabetes mellitus in the population of Jodhpur city of Rajasthan State (India). The present cross sectional study analyzes ABO blood group among 400 subjects of every age taken randomly from the local population of Jodhpur city in the duration of January to may 2013. Out of 400subjects, 200 were normal healthy (97 male and 103 female) students of Dr. S.N. Medical College, Jodhpur and remaining 200 were DM patients (53 type 1(Insulin dependent) &147 Type 2 (Non insulin dependent)) attending the OPD of MDM & Umaid Hospital, Jodhpur. ABO blood groups of all subjects were determined by slide agglutination method. Data were analyzed by 'one sample chi square test'. The results obtained in this study indicated that there was no significant difference in the frequency of ABO blood groups in Controls and Diabetic Patients of both Type I & II in all studied subjects (males, females and subjects ...

The present study is undertaken to estimate the plasma homocysteine level in cerebrovascular acci... more The present study is undertaken to estimate the plasma homocysteine level in cerebrovascular accident cases with the aim to search for the prevalence of elevated homocysteine level in cerebrovascular accident (Stroke) among patient of western Rajasthan. This study was conducted on 50 stroke patient (Case group) and 50 normal subjects (Control group)of both sex and aged between 30 yrs-75 yrs. Both groups were subjected to routine investigations like Blood sugar, Lipid profile, and Plasma Hcy concentration. A detail medical history was obtained. All study groups were subjected to investigation including neurological examination, blood examination, renal function, urine examination, chest X ray & ECG, and CT/MRI. Plasma Hcy concentration was measured by Chemiluminescent Magnetic Immunoassay (CMIA), using plasma on the ARCHITECT I System from standard laboratory in all the stroke patients of case group. Similar investigations were done for control group except CT Scan/MRI. In results th...

With regular cohabitation without any protection if women do not conceive for at least a period o... more With regular cohabitation without any protection if women do not conceive for at least a period of one year is labelled as infertility. It is based on the observation that most of the normal couples achieve conception within a year of initiation of regular sex. Infertility affects approximately 15% of all couples trying to conceive. It’s a major clinical problem, affecting people medically and psychologically. Male factor infertility is the major cause in roughly half of the cases, and no identifiable cause can be found in over 25% of infertile males. Out of many causes of male infertility Oxidative stress (OS) has been attributed to affect the fertility status and thus, it has been studied extensively in recent years. Excessive production of free radicals or reactive oxygen species (ROS) can damage sperm and ROS has been extensively studied as one of the major mechanism of infertility

Cardiovascular diseases are emerging as one of the leading causes of morbidity and mortality in t... more Cardiovascular diseases are emerging as one of the leading causes of morbidity and mortality in the Indian population. The major risk factors contributing to cardiovascular diseases include hypertension, diabetes mellitus, smoking, hypercholesterolemia and family history of coronary artery disease. Among which hypertension contributes the most. Arterial stiffness, a major contributor of atherosclerosis, has been shown to have positive relationship with systolic hypertension, coronary artery disease, stroke and heart failure. Hence measurement of arterial stiffness seems to be an important tool to assess cardiovascular risk in hypertensive patients. So the present study was undertaken to find out the relationship between arterial stiffness and hypertension in Jodhpur city. 103 subjects with systolic blood pressure >120 mm Hg, were taken, ranging between 25-90 years of age. Anthropometric measures were done manually while all other measures including the parameters of arterial stif...

Scientific studies confirm that it is the evaluation system rather than educational objectives, c... more Scientific studies confirm that it is the evaluation system rather than educational objectives, curriculum or instructional techniques that have the most profound impact on students learning. The present study was done to find out the coverage of different sub-divisions of physiology in written examination and its comparison with the teaching hours devoted to the teaching of each topic. For the analyses of the written question papers, all the questions of the first M.B.B.S examination of Rajasthan University of Health Sciences from 2001 to 2006 were examined and analyzed for content validity. The results of this analysis were then compared with percentage frequency of teaching hours devoted to each topic. Highest percentage frequency of coverage was with cardiovascular system (15.40%) while lowest was for exercise physiology (1.26%). 45% coverage of all the segments was asked from CVS, blood and CNS including special senses. The percentage frequency of classes for these topics was a...

Background: ISH is the most common type of hypertension in people over 60 years of age and increa... more Background: ISH is the most common type of hypertension in people over 60 years of age and increase in SBP being the principal characteristic in this population. Interestingly, data from a number of studies suggest that ISH is also prevalent in adolescents and young adults but findings from previous studies examining this question are inconclusive, so the aim of our study is to know prevalence and determinants of ISH in young healthy individuals. Method: We performed a cross section study on 400 young individuals between 18 to 30 years in western Rajasthan. The participants were then subjected to a set of questionnaire which included socio-demography determinants (age, sex, occupation and annual household income), personal habits (dietary habits, smoking, alcohol consumption), past history and family history of hypertension. They were then subjected to the measurement of height, weight, pulse rate, blood pressure, fasting blood sugar and serum cholesterol level. Result: In our study...

Arterial stiffness and type 2 diabetes Mellitus (T2DM) are associated with increased risk for car... more Arterial stiffness and type 2 diabetes Mellitus (T2DM) are associated with increased risk for cardiovascular disease (CVD) and mortality. By assessing the arterial stiffness in diabetics, the risk of CVD could be quantified in T2DM. Aim of this cross sectional study to assess the association of arterial stiffness and T2DM. 25 normal and 60 atleast 1year history of T2DM males, aged 25 to 65 years of western Rajasthan were examined for arterial stiffness. Anthropometric data such as weight and height were taken to derive Body Mass Index (BMI). Right and left brachial ankle Pulse Wave Velocities (Br Ank PWV) and carotid to femoral Pulse Wave Velocity (cf PWV) were taken as indices of regional and central arterial stiffness respectively. On other hand right and left, brachial and ankle Arterial Stiffness Indexes (ASI) are taken as indices for corresponding local arterial stiffness. These were measured by an automated device Periscope (developed by genesis medical system, Hyderabad) base...

Background: Physical fitness is required not only by athletes for better performance but also by ... more Background: Physical fitness is required not only by athletes for better performance but also by non-athletes for maintenance of physical and mental health. Objective: The aim of the study was to assess the role of aerobic exercise on Haemoglobin and % Saturation of Haemoglobin among untrained and trained subjects. Methods: The present study was conducted in the Department of Physiology, Dr. S.N. Medical College, Jodhpur after ethical approval. Informed written consent was obtained from all the subjects included in the study. In this study total 200 male subjects were included, which were further divided in two groups. Group I: included 100 randomly selected untrained male subjects (medical students) at the beginning of their training period. Group II: It included the same 100 healthy medical students, as in group I, but after their training period of 3 months duration. Group III: 100 randomly selected male Athletes participating in city/district/state competition constituted the tr...

Objectives: This study was done to establish the normal values of various haematological paramete... more Objectives: This study was done to establish the normal values of various haematological parameters for healthy adult of Western Rajasthan (males and females) and to compare these values with those obtained for other population in both India and tropical countries. Methods: This study was under taken in reference adult Western Rajasthan Population in the area of Jodhpur, India. A total 1000 healthy volunteers whose ages ranged between 20–50 years, were investigated. All laboratory analysis was conducted under standardized conditions atL.N. Memorial Hospital & Research Centre, Jodhpur.Results:In Males, the mean Haemoglobin concentration (Hb) of 14.03 g/dl and Haematocrit (HCT) ratio of 44% were significantly higherthan femalevalue of 12.50 g/dl and 40% respectively. The mean Red Blood Cell (RBC) countof 4.90 x 106/μL in males was also significantly higher than the corresponding value of 4.50 x 106/μL infemales (p<0.05). The value of Mean Corpuscular Volume (MCV) in males (88.12 fL...

Background: The ECG pattern in paediatric population varies with age and sex. The majority of cha... more Background: The ECG pattern in paediatric population varies with age and sex. The majority of changes occur during the first year of life due to changes in cardiac anatomy and haemodynamics soon after birth, as a result of the cessation of placental circulation and establishing cardiopulmonary circulation. Therefore the majority of normal adult values cannot be used in the newborn. Methods: This study was carried out in 200 children, with equal males and females, divided into 5 age groups from 0–14 years. Single chest lead ECG machine with standard setting (10 mm/mV. with a standard paper speed of 25 mm/sec.) was used in the study for recording of ECG. The electrocardiogram was recorded in all 12 leads and carefully interpreted for heart rate, rhythm, intervals and duration for evaluation of developmental, age and sex related changes. Results: The heart rate was increased in first 1–2 month of age and then in the following 6 months it remained stable and then slowly declined after 1...