Dr Sabeena Jan - Academia.edu (original) (raw)

Papers by Dr Sabeena Jan

Research paper thumbnail of Clinical Study of Extrapulmonary Head and Neck Tuberculosis: A Single-Institute 10-year Experience

International Archives of Otorhinolaryngology, 2015

Introduction Although the incidence of tuberculosis (TB) in Japan has been decreasing yearly, Jap... more Introduction Although the incidence of tuberculosis (TB) in Japan has been decreasing yearly, Japan remains ranked as an intermediate-burden country for TB. Objective This study aims to investigate the current situation of head and neck extrapulmonary TB (EPTB) diagnosed in our department. Methods We retrospectively reviewed the clinical records of 47 patients diagnosed with EPTB in the head and neck in our department between January 2005 and December 2014. The extracted data included sex and age distribution, development site, chief complaint, presence or absence of concomitant active pulmonary TB (PTB) or history of TB, tuberculin skin test (TST) results, interferon-gamma release assay (IGRA) results, and duration from the first visit to the final diagnosis of EPTB. Results The subjects consisted of 20 men and 27 women, and age ranged from 6 to 84 years. The most common site was the cervical lymph nodes (30 patients), with the supraclavicular nodes being the most commonly affected...

Research paper thumbnail of Deranged Pulmonary Function Tests in Allergic Rhinitis in North Indian Patients

Clinical Medicine Insights: Ear, Nose and Throat, 2019

Introduction: Significant associations between allergic rhinitis and bronchial asthma have been e... more Introduction: Significant associations between allergic rhinitis and bronchial asthma have been established and as a result of bronchial hyper-responsiveness, patients can have deranged pulmonary function tests. We aim to compare previous such studies with the result of our study done in India wherein we identify among allergic rhinitis patients who despite not having overt asthmatic symptoms, have pulmonary function derangements, quite possibly at a subclinical disease level. Materials and Methods: We studied 74 patients of allergic rhinitis and after meticulous clinical work up, they underwent blood tests including hemogram, absolute eosinophil count, and total serum IgE followed by pulmonary function tests. Results: Out of 74 patients 60 (81%) had intermittent allergic rhinitis whereas only 14 (19%) had persistent allergic rhinitis. Pulmonary function tests showed reversible obstruction, ie, >10% improvement in FEV1 with inhaled bronchodilators (as seen in asthma) in 18 (24.3%...

Research paper thumbnail of Acute tuberculous abscess of the larynx. An unusual presentation

A 26-year-old young male presented in our ENT OPD with chief complaints of a painful swelling on ... more A 26-year-old young male presented in our ENT OPD with chief complaints of a painful swelling on left side of the neck over the thyroid region for one week. He had no symptoms of dysphagia, hoarseness of voice or cough and no constitutional symptoms of fever, weight loss or loss of appetite. There was no history of contact with tuberculosis patient. On examination he was conscious, well-built and afebrile. There was a small ill-defined, tender indurated area around 1 cm×1 cm over left side of thyroid region with hyperemic overlying skin (Fig. 1). The patient had already taken a course of antibiotics prescribed by a private practitioner but there was no relief. His indirect laryngoscopic examination was normal. There was no cervical lymphadenopathy. FNAC of the swelling was done which was suggestive of sub-acute thyroiditis. His hematological and biochemical investigations were normal except mildly raised T3 (7.75 pg/ml). He had negative serology for HIV. He was treated with oral steroids and oral antibiotics in view of subacute thyroiditis and called for follow up. He returned after 7 days with an abscess over the left side thyroid region. It was around 4 cm×3.5 cm in size, fluctuant and tender on palpation. Ultrasonography of the neck showed a well-defined superficial collection in neck around 3.5 cm×1.5 cm×2.5 cm with a volume of 6 cm suggestive of

Research paper thumbnail of Sinonasal tuberculosis: Report of three atypical cases

Indian Journal of Tuberculosis, 2016

Primary sinonasal/nasal tuberculosis is rare amongst the commonly seen cases of extrapulmonary tu... more Primary sinonasal/nasal tuberculosis is rare amongst the commonly seen cases of extrapulmonary tuberculosis. We report three cases, two of primary sinonasal tuberculosis and one case of nasal tuberculosis in otherwise healthy patients. The diagnosis was based on radiological and histopathological findings. Treatment with antitubercular drug therapy was successful in all three of them. Sinonasal region tuberculosis, despite its rarity, should be added to differential diagnosis of nasal and paranasal sinus disorders particularly with intractable symptoms. Radiological imaging and nasal endoscopy with biopsy should be supplemented for confirmation.

Research paper thumbnail of Clinical Study of Extrapulmonary Head and Neck Tuberculosis: A Single-Institute 10-year Experience

International Archives of Otorhinolaryngology, 2015

Introduction Although the incidence of tuberculosis (TB) in Japan has been decreasing yearly, Jap... more Introduction Although the incidence of tuberculosis (TB) in Japan has been decreasing yearly, Japan remains ranked as an intermediate-burden country for TB. Objective This study aims to investigate the current situation of head and neck extrapulmonary TB (EPTB) diagnosed in our department. Methods We retrospectively reviewed the clinical records of 47 patients diagnosed with EPTB in the head and neck in our department between January 2005 and December 2014. The extracted data included sex and age distribution, development site, chief complaint, presence or absence of concomitant active pulmonary TB (PTB) or history of TB, tuberculin skin test (TST) results, interferon-gamma release assay (IGRA) results, and duration from the first visit to the final diagnosis of EPTB. Results The subjects consisted of 20 men and 27 women, and age ranged from 6 to 84 years. The most common site was the cervical lymph nodes (30 patients), with the supraclavicular nodes being the most commonly affected...

Research paper thumbnail of Deranged Pulmonary Function Tests in Allergic Rhinitis in North Indian Patients

Clinical Medicine Insights: Ear, Nose and Throat, 2019

Introduction: Significant associations between allergic rhinitis and bronchial asthma have been e... more Introduction: Significant associations between allergic rhinitis and bronchial asthma have been established and as a result of bronchial hyper-responsiveness, patients can have deranged pulmonary function tests. We aim to compare previous such studies with the result of our study done in India wherein we identify among allergic rhinitis patients who despite not having overt asthmatic symptoms, have pulmonary function derangements, quite possibly at a subclinical disease level. Materials and Methods: We studied 74 patients of allergic rhinitis and after meticulous clinical work up, they underwent blood tests including hemogram, absolute eosinophil count, and total serum IgE followed by pulmonary function tests. Results: Out of 74 patients 60 (81%) had intermittent allergic rhinitis whereas only 14 (19%) had persistent allergic rhinitis. Pulmonary function tests showed reversible obstruction, ie, >10% improvement in FEV1 with inhaled bronchodilators (as seen in asthma) in 18 (24.3%...

Research paper thumbnail of Acute tuberculous abscess of the larynx. An unusual presentation

A 26-year-old young male presented in our ENT OPD with chief complaints of a painful swelling on ... more A 26-year-old young male presented in our ENT OPD with chief complaints of a painful swelling on left side of the neck over the thyroid region for one week. He had no symptoms of dysphagia, hoarseness of voice or cough and no constitutional symptoms of fever, weight loss or loss of appetite. There was no history of contact with tuberculosis patient. On examination he was conscious, well-built and afebrile. There was a small ill-defined, tender indurated area around 1 cm×1 cm over left side of thyroid region with hyperemic overlying skin (Fig. 1). The patient had already taken a course of antibiotics prescribed by a private practitioner but there was no relief. His indirect laryngoscopic examination was normal. There was no cervical lymphadenopathy. FNAC of the swelling was done which was suggestive of sub-acute thyroiditis. His hematological and biochemical investigations were normal except mildly raised T3 (7.75 pg/ml). He had negative serology for HIV. He was treated with oral steroids and oral antibiotics in view of subacute thyroiditis and called for follow up. He returned after 7 days with an abscess over the left side thyroid region. It was around 4 cm×3.5 cm in size, fluctuant and tender on palpation. Ultrasonography of the neck showed a well-defined superficial collection in neck around 3.5 cm×1.5 cm×2.5 cm with a volume of 6 cm suggestive of

Research paper thumbnail of Sinonasal tuberculosis: Report of three atypical cases

Indian Journal of Tuberculosis, 2016

Primary sinonasal/nasal tuberculosis is rare amongst the commonly seen cases of extrapulmonary tu... more Primary sinonasal/nasal tuberculosis is rare amongst the commonly seen cases of extrapulmonary tuberculosis. We report three cases, two of primary sinonasal tuberculosis and one case of nasal tuberculosis in otherwise healthy patients. The diagnosis was based on radiological and histopathological findings. Treatment with antitubercular drug therapy was successful in all three of them. Sinonasal region tuberculosis, despite its rarity, should be added to differential diagnosis of nasal and paranasal sinus disorders particularly with intractable symptoms. Radiological imaging and nasal endoscopy with biopsy should be supplemented for confirmation.