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Papers by DrZeinab Abou-Elnaga

Research paper thumbnail of Insecticidal bioactivity of eco-friendly plant origin chemicals against Culex pipiens and Aedes aegypti (Diptera: Culicidae)

Journal of entomology and zoology studies, 2014

Mosquitoes are the most important medical insects in the entire world. Natural chemicals have man... more Mosquitoes are the most important medical insects in the entire world. Natural chemicals have many advantages over the conventional ones in case of mosquito control. The aim of this study is to evaluate the larvicidal and adulticidal bioactivity of some plant origin chemicals against Culex pipiens and Aedes aegypti (Diptera: Culicidae). The chemicals under investigation of Myristicin, Sage oil and Nutmeg oil were isolated and structurally elucidated using GC/MS, and 1H-NMR, spectra that compared with the authentic samples. Myristicin was the highest larvicidal bioactive compound with LC50 values 18.3 ppm against Cx. pipiens and Ae. aegypti, larvae after 24 h of treatment, respectively. The rest of the tested materials showed also high larvicidal and adulticidal activities that may be related to their volatile bioactive constituents. From the results of this study; its highly recommend the tested natural chemicals to be an alternative eco-friendly source for mosquito control chemicals.

Research paper thumbnail of Insecticidal Metabolites from the Green Alga Caulerpa racemosa

Clean-soil Air Water, 2010

The purpose of this study is the isolation and identification of metabolites from the green alga ... more The purpose of this study is the isolation and identification of metabolites from the green alga Caulerpa racemosa and assaying them against the medically important mosquito Culex pipiens. The chloroform/methanol extract of the green alga C. racemosa afforded a number of metabolites, as caulerpin (1), caulerpynyne (3), phytol (4), 10-keto-3,7,11-trimethyldodecanoic acid (5), a number of unsaturated compounds in addition to caulerpinic acid (2), the alkaline hydrolysis product of caulerpin. In summary, the larvicidal activity of caulerpin and caulerpinic acid were tested against C. pipiens mosquito (filarial victor) leading to the identification of novel effective mosquitocidal compounds.

Research paper thumbnail of New Larvicidal Acetogenin from the Red Alga Laurencia papillosa

CLEAN - Soil, Air, Water, 2011

A new C 15 acetogenin, cyclic enyne (12E)-cis-maneonene-E (1) and (12Z)-trans-maneonene-B (2), to... more A new C 15 acetogenin, cyclic enyne (12E)-cis-maneonene-E (1) and (12Z)-trans-maneonene-B (2), together with different secondary metabolites including sesquiterpenoid 2,10dibromo-3-chloro-a-chamigrene (3) and fatty acid aldehydes (4-8) were isolated from the petroleum ether extract of a red alga, identified as Laurencia papillosa, collected from the Saudi Red Sea coast. The L. papillosa crude extract and its active ingredient acetogenin (1) have been evaluated for the ability to control two main economically important pests, the confused flour beetle larvae Tribolium confusum and Culex pipiens mosquito larvae. Compound 1 showed high potential as a natural insecticide against these two pests. In the case of T. confusum larvae, the LD 50 values were 0.21 and 0.16% after 6 and 12 days of treatment with crude extract and acetogenin, respectively. On the other hand, the resulting LC 50 values of mosquito larvae bioassay were 30.7, 36.9, and 41.8 ppm after 24 h treatment against 2nd, 3rd, and 4th larval instars, respectively. Also, an increase of the insecticidal effects against mosquito larvae was recorded after extending treatment time to 48 h.

Research paper thumbnail of Insecticidal bioactivity of eco-friendly plant origin chemicals against Culex pipiens and Aedes aegypti (Diptera: Culicidae)

Journal of entomology and zoology studies, 2014

Mosquitoes are the most important medical insects in the entire world. Natural chemicals have man... more Mosquitoes are the most important medical insects in the entire world. Natural chemicals have many advantages over the conventional ones in case of mosquito control. The aim of this study is to evaluate the larvicidal and adulticidal bioactivity of some plant origin chemicals against Culex pipiens and Aedes aegypti (Diptera: Culicidae). The chemicals under investigation of Myristicin, Sage oil and Nutmeg oil were isolated and structurally elucidated using GC/MS, and 1H-NMR, spectra that compared with the authentic samples. Myristicin was the highest larvicidal bioactive compound with LC50 values 18.3 ppm against Cx. pipiens and Ae. aegypti, larvae after 24 h of treatment, respectively. The rest of the tested materials showed also high larvicidal and adulticidal activities that may be related to their volatile bioactive constituents. From the results of this study; its highly recommend the tested natural chemicals to be an alternative eco-friendly source for mosquito control chemicals.

Research paper thumbnail of Insecticidal Metabolites from the Green Alga Caulerpa racemosa

Clean-soil Air Water, 2010

The purpose of this study is the isolation and identification of metabolites from the green alga ... more The purpose of this study is the isolation and identification of metabolites from the green alga Caulerpa racemosa and assaying them against the medically important mosquito Culex pipiens. The chloroform/methanol extract of the green alga C. racemosa afforded a number of metabolites, as caulerpin (1), caulerpynyne (3), phytol (4), 10-keto-3,7,11-trimethyldodecanoic acid (5), a number of unsaturated compounds in addition to caulerpinic acid (2), the alkaline hydrolysis product of caulerpin. In summary, the larvicidal activity of caulerpin and caulerpinic acid were tested against C. pipiens mosquito (filarial victor) leading to the identification of novel effective mosquitocidal compounds.

Research paper thumbnail of New Larvicidal Acetogenin from the Red Alga Laurencia papillosa

CLEAN - Soil, Air, Water, 2011

A new C 15 acetogenin, cyclic enyne (12E)-cis-maneonene-E (1) and (12Z)-trans-maneonene-B (2), to... more A new C 15 acetogenin, cyclic enyne (12E)-cis-maneonene-E (1) and (12Z)-trans-maneonene-B (2), together with different secondary metabolites including sesquiterpenoid 2,10dibromo-3-chloro-a-chamigrene (3) and fatty acid aldehydes (4-8) were isolated from the petroleum ether extract of a red alga, identified as Laurencia papillosa, collected from the Saudi Red Sea coast. The L. papillosa crude extract and its active ingredient acetogenin (1) have been evaluated for the ability to control two main economically important pests, the confused flour beetle larvae Tribolium confusum and Culex pipiens mosquito larvae. Compound 1 showed high potential as a natural insecticide against these two pests. In the case of T. confusum larvae, the LD 50 values were 0.21 and 0.16% after 6 and 12 days of treatment with crude extract and acetogenin, respectively. On the other hand, the resulting LC 50 values of mosquito larvae bioassay were 30.7, 36.9, and 41.8 ppm after 24 h treatment against 2nd, 3rd, and 4th larval instars, respectively. Also, an increase of the insecticidal effects against mosquito larvae was recorded after extending treatment time to 48 h.