Dragan Krasic - Academia.edu (original) (raw)

Papers by Dragan Krasic

Journal of Stomatology, Oral and Maxillofacial Surgery, 2018

IntechOpen eBooks, Feb 13, 2024

The frontoethmoidal region is an anatomical complex of the middle and upper mass of the face, pla... more The frontoethmoidal region is an anatomical complex of the middle and upper mass of the face, placed at the mouth of numerous regions, such as the upper jaw, cranium, orbital and nasal region. The multitude of anatomical elements in a small space with a specific function makes this region very demanding for the diagnosis and treatment of pathological entities. Extensive tumors of this region are a special diagnostic and therapeutic problem. Surgical treatment includes rhinotomy, sinusotomy, orbitotomy, frontectomy, and other types of operations. In the case of skull base extension, the situation becomes more complicated, which leads to the need for the cooperation of several specialists and modification of the surgical technique. A special problem in this region is adequate reconstruction. More specialists perform surgical procedures in these regions. These include maxillofacial surgeons, ENT (ear, nose, and throat) specialists, neurosurgeons, oncological surgeons, and ophthalmologists.

Acta Stomatologica Naissi, 2003

The preset study describes the functional lower lip reconstruction by the mental V-Y island neuro... more The preset study describes the functional lower lip reconstruction by the mental V-Y island neurovascular advancement flap. In the male patient 84 years of age, bleeding planocellular lateral lip cancer was diagnosed. After the surgical excision of planocellular cancer, postresectional lip defect was 52 mm long and 32 mm high. Advancement V-Y island neurovascular muscle-cutaneous flap, nourished and innervated by a. and n. mentalis was used in lip reconstruction. The remnants of the orbicularis oris muscle, as well as the depressor anguli oris muscle and depressor labii inferioris muscle with their motor branches of the facial nerve were used for the orbicular sphincter reconstruction. The vermilion was reconstructed by the local mucosal flap. The patient was discharged after seven days with completely vital V-Y island neurovascular muscle-cutaneous flap for home care.

Journal of Cranio-Maxillofacial Surgery, 2008

s, EACMFS XIX Congress Histological specimens were studied by comparative genomic hybridisation. ... more s, EACMFS XIX Congress Histological specimens were studied by comparative genomic hybridisation. Each tumour was studied on chromosomal level and confirmed our suspicion. We found two different tumours. Tongue tumour was carcinoma with many genetical reforma malformations. On the other hand, buccal carcinoma genetical examination showed one gentical malformation, 8q22.3qter. Examination showed two different tumours with different therapeutic response. Our case showed, that ordinary histological diagnostic methods are insufficient and would be eked out by examination with genetic methods.

Acta stomatologica Naissi, 2017

Uvod: Veliku grupu benignih koštanih tumora vilica predstavljaju fibro-koštani tumori. Osnovu pat... more Uvod: Veliku grupu benignih koštanih tumora vilica predstavljaju fibro-koštani tumori. Osnovu patofiziološkog procesa ove vrste tumora predstavlja zamena normalnog koštanog tkiva fibroznim tkivom. Cemento-osificirajući fibrom (COF) pripada ovoj grupi tumora. Prikaz slučaja: Predstavljen je redak slučaj COF u maksili i maksilarnom sinusu kod četrdesetogodišnjeg muškarca .U početnom stadijumu se COF razvijao asimptomatski, kao kod većine benignih tumora. U kasnijim stadijumima, zavisno od lokalizacije, pre svega, pojavili su se drugi simptomi, kao što je deformitet lica,vilica i glave, oftalmološke smetnje, parestezije zbog kompresije nerava i dr. Urađena je subtotalna maksilektomija Weber-Fergusson pristupom. Zaključak: U našem prikazu slučaja predstavili smo pacijenta sa retkom lokalizacijom COF. Za postavljenje definitivne dijagnoze COF, neophodan je, pre svega, MSCT-om i angiogram. Hirurška terapija je jedina metoda lečenja. Postoperativno praćenje pacijenta je neophodno zbog mogućih recidiva ili drugih komplikacija, uz kontrolni MSCT.

─ The aim of this study is to investigate the impact of orthodontic brace on the electric field d... more ─ The aim of this study is to investigate the impact of orthodontic brace on the electric field distribution and amount of the absorbed energy from the cell phone within the teeth. A comparative analysis of the models (child and adult) with and without brace has been carried out due to different morphological and tissue characteristics of child’s and adult’s head. The 3D realistic models of the child’s and adult’s head, with the jaw having the orthodontic brace, have been designed. The shapes and features of the child and adult head model, as well as the distance between the electromagnetic source and the exposed object, have an important role in the evaluation of the Specific Absorption Rate (SAR). The applied procedure is based on the numerical solution of the electromagnetic waves propagation equations. The numerical analysis has been performed at the frequency of 3G (0.9GHz). The obtained results are represented within the teeth positioned on the side of the electromagnetic radi...

Medicinski glasnik : official publication of the Medical Association of Zenica-Doboj Canton, Bosnia and Herzegovina, 2015

Aim To describe demographic and histomorphological characteristics of 139 patients with epithelia... more Aim To describe demographic and histomorphological characteristics of 139 patients with epithelial salivary gland tumors in the Southeastern Serbia population. Methods A total number of 139 patients with epithelial tumors arising in major and minor salivary glands in the period 2010-2012 was evaluated. After standard tissue proceeding, the routine haematoxylin-eosin (HE) and histochemical alcian blue-periodic acid-Schiff (AB - PAS) methods were used for histomorphological examination. Results Among 139 patients, 102 (73.38%) had benign, and 37 (26.62%) malignant tumors. The majority of tumors were localized in the parotid gland, in 117 (84.17%) patients. Among benign tumors there were 50 (49.02%) pleomorphic adenoma, 48 (47.06%) Warthin's tumor, two (1.96%) myoepithelioma, and two (1.96%) oncocytoma. In the group of malignant tumors the most common was mucoepidermoid carcinoma, in 12 (32.43%) patients, carcinoma ex pleomorphic adenoma in six (16.22%), adenoid cystic carcinoma in...

Journal of Oral Science, 2003

This paper reports the results of experimental use of glass-ionomer microimplants in the augmenta... more This paper reports the results of experimental use of glass-ionomer microimplants in the augmentation of the maxillary alveolar ridge in dogs. The study included ten adult mongrel dogs 5 years of age, weighing between 50 and 70 pounds (25-30 kg), divided into 2 groups of 5 dogs each. In both groups, the maxillary 4th premolar and 1st molar were removed after the elevation of a buccal mucoperiosteal flap. The alveolar bone adjacent to the extracted teeth was also removed. In the experimental group (5 dogs), Ionogran(R) a glass-ionomer microimplants (GIMIs) (Ionogran(R) particle size of 0.5-1.0 mm, IONOS Medizinische Produkte GmbH & Co. KG, D-8031 Seefeld, Gemany) were used for augmentation and were inserted in the created defects. The extraction sockets and bone defects were augmented with an average amount of 2 g of GIMIs. In the control group, the bone defects were left unfilled as a control for bone healing. Histological examination showed that the glass-ionomer microimplants were extremely osteoconductive and inert materials. Stimulation of growth of new bone tissue in contact with the glassionomer microimplants was evident. No inflammatory cells were detected on or adjacent to the GIMIs. In the control group, incomplete bone healing with fibrous scar tissue and inflammatory cells was noted. These results indicate that glass-ionomer microimplants represent highly osteoconductive and biocompatible materials for use in bone surgery. (

Journal of Oral and Maxillofacial Surgery, 2001

Dentomaxillofacial Radiology, 2009

Schwannoma is a benign nerve tumour that originates from Schwann cells, which cover peripheral ne... more Schwannoma is a benign nerve tumour that originates from Schwann cells, which cover peripheral nerves. Intraosseous schwannoma of the jaw is rare. Primary schwannoma of the mandible presenting as a periapical radiolucency on a non-vital endodontically treated tooth has rarely been referred to in the English medical literature. A rare case of intraosseous schwannoma is reported in a 23-year-old woman. The patient presented clinically with a painful swelling on the right side of the mandible and with a radiologically ill-defined unilocular periapical lesion around the mesial root of the endodontically treated first molar. Surgical treatment involved complete excision of the lesion with a mesial and distal root resection. Histological and immunohistochemical examination showed that the lesion was a primary intraosseous schwannoma of the mandible. Immunohistochemical examination showed a positive and strong reaction for S-100 protein, characteristic of neural tumours. 1 year following surgery, there were no regional recurrences. Radiographically, mandibular intraosseous schwannoma is difficult to differentiate from bone tumours such as ameloblastoma, myxoma, fibrous dysplasia, neurofibroma, central giant cell lesion or periapical lesion, so it should be included in the list of possible periapical pathoses.

Serbian Journal of Electrical Engineering

Body temperature is an important indicator that may indicate the possibility of the existence of ... more Body temperature is an important indicator that may indicate the possibility of the existence of various pathological conditions and diseases. In the head and neck area, an infrared camera allows accurate temperature measurements of all regions of interest. The analysis of temperature characteristics of the region of interest of the head and neck in healthy subjects in terms of comparison of values in relation to the side of the face in the same person, and the comparison of values relative to the sex of the subjects is the topic of this research. These analyses are performed to create temperature maps of the face and determine physiological values. The research was conducted with the participation of 30 healthy people, 16 women and 14 men of different ages. Thermal imaging was performed in controlled conditions with infrared thermographic camera Varioscan 3021ST, while the software package IRBIS Professional 2.2 was used for thermogram analysis. Results show that the temperatures i...

Vojnosanitetski pregled, 2009

Bacground/Aim. Sj?gren's syndrome is a chronic autoimmune systemic disease characterized by p... more Bacground/Aim. Sj?gren's syndrome is a chronic autoimmune systemic disease characterized by polyglandular tissue destruction, leading to keratoconjunctivitis sicca and xerostomia. These patients have 44-fold increased risk of developing salivary gland lymphoma, of which 80% are marginal zone (MALT) type. Having in mind that criteria for distinguishing benign lymphoepithelial lesions from MALT lymphoma are obscure, the aim of this study was to provide practical information that could be integrated into diagnostic practice. Methods. Among 32 parotidectomies, 27 cases were identified as having benign lymphoepithelial disorders and 5 cases low grade MALT lymphoma. Histological sections were stained routinely with hematoxylin and eosin (H&E and special stains. Immunohistochemical study was performed by LSAB2 method, by using primary antibodies for CD20, CD3, Kappa and Lambda light chains and Cytokeratin (Dako Denmark). Results. The 27 patients with Sj?gren's sialoadenitis (22 wom...

Srpski arhiv za celokupno lekarstvo, 2010

Introduction. Dermoid and epidermoid cysts of the orbit belong to choristomas, tumours that origi... more Introduction. Dermoid and epidermoid cysts of the orbit belong to choristomas, tumours that originate from the aberrant primordial tissue. Clinically, they manifest as cystic movable formations mostly localized in the upper temporal quadrant of the orbit. They are described as both superficial and deep formations with most frequently slow intermittent growth. Apart from aesthetic effects, during their growth, dermoid and epidermoid cysts can cause disturbances in the eye motility, and in rare cases, also an optical nerve compression syndrome. Case Outline. In this paper, we described a child with a congenital orbital dermoid cyst localized in the upper-nasal quadrant that was showing signs of a gradual enlargement and progression. The computerized tomography revealed a cyst of 1.5-2.0 cm in size. At the Maxillofacial Surgery Hospital in Nis, the dermoid cyst was extirpated in toto after orbitotomy performed by superciliary approach. Postoperative course was uneventful, without infla...

Nigerian Journal of Clinical Practice, 2018

Meningiomas constitute a large group of tumors of the central nervous system, with the prevalence... more Meningiomas constitute a large group of tumors of the central nervous system, with the prevalence of 18%–20%. Extracranial localization of meningeomas could appear due to their extracranial origin or due to the spreading of intracranial meningeomas. In this paper, we present our 15 years' experience in the diagnosis and treatment of extra- and intracranial meningiomas invading the head-and-neck region. In the period from 2001 to 2016 at our clinic, there were five patients (three men and two women), with meningiomas of extracranial origin or meningiomas of intracranial origin, spreading into the head-and-neck region. All patients were surgically treated, with the addition of adjuvant radiation therapy in some of the cases. Postoperative and postirradiation complications were described as well.

Journal of stomatology, oral and maxillofacial surgery, 2018

Intraosseous lipoma appears less frequently in the maxilla than in the mandible. The initial phas... more Intraosseous lipoma appears less frequently in the maxilla than in the mandible. The initial phase of tumor development is characterized by asymptomatic growth, followed by the presence of pain and paresthesia in the later stage. We report the case of a 43-year-old female patient who contacted a doctor because of periodic pains and stupor in the left side of the upper jaw. The exostosis-like formation was found by palpation, subsequently raising suspicion of an odontogenic tumor on the basis of panoramic imaging (dental orthopan). The intraosseous lipoma was histopathologically diagnosed after surgical procedure and standardized treatment of removed tumefaction. Clinical features and x-ray findings of the intraosseous lipoma within the maxillary region are generally blurred. Surgery is the recommended treatment, and histopathology analysis is of utmost importance for the final diagnosis.

Introduction/Objective. Nasolacrimal duct obstruction with consequent epiphora and the developmen... more Introduction/Objective. Nasolacrimal duct obstruction with consequent epiphora and the development of dacryocystitis (DC) represents a common pathological entity in the clinical practice of ophthalmologists and maxillofacial surgeons. The etiology of DC is multifactorial and still has not been clarified in detail. It is considered that ascending infections from the nasal cavity and paranasal sinuses, injuries and surgical interventions in the middle third of the face, dacryoliths, tumors of the lacrimal sac and surrounding structures may be some of the etiological factors of nasolacrimal duct obstruction. The aim of this study is to present clinical characteristics and surgical treatment of DC. Methods. A retrospective study was carried out. It covered a period of 10 years during which 49 patients with clinically verified DC were treated after surgical examination and complete diagnostics. Out of the total number, 37 patients underwent surgery. Results. The occurrence of predisposin...

PURPOSE To investigate both the clinicopathological and immunohistochemical characteristics of a ... more PURPOSE To investigate both the clinicopathological and immunohistochemical characteristics of a very rare skin cancer - Merkel cell carcinoma (MCC) - and to review the relevant literature. METHODS The study group was composed of 12 patients, with mean age 53.08±10.26 years. Multiple subcutaneous masses and lymph node metastases were surgically removed. Paraffin blocks of formaldehyde-fixed tumor tissue were cut and stained for histological, histochemical and immunohistochemical studies. The following antibodies (Dacopatt) were used: Chromogranin A, CK20, CK7, Melan A, CD20 and CD45Ro. RESULTS The tumors involved the dermis while sparing the epidermis. The most frequently affected sites were sun-exposed skin (8 patients on the head and neck) and the most common histological subtype of MCC was the intermediate variant. Six patients had lymph node metastasis and 2 had locoregional recurrences. Haematogenous lung metastases of MCC and primary located in the trunk were found only in our...

Polish Journal of Cardio-Thoracic Surgery