Dragan Piljic - Academia.edu (original) (raw)

Papers by Dragan Piljic

Research paper thumbnail of Clinical and Laboratory Characteristics of Acute Community-Acquired Urinary Tract Infections in Adult Hospitalised Patients

Bosnian Journal of Basic Medical Sciences, Feb 20, 2010

Research paper thumbnail of Giant Femoral Artery Pseudoaneurysm Diagnosed 25 Years after War Injury

Journal of biomedical research & environmental sciences, Feb 26, 2019

Research paper thumbnail of The Association Between Perioperative Point-of-Care Platelet Function Analyses and Transfusion Requirements in Cardiac Surgery: Methodological Considerations

Thoracic and Cardiovascular Surgeon, Feb 18, 2021

Research paper thumbnail of Challenges in diabetic foot treatment during pandemic of COVID-19

Saudi Medical Journal, Feb 1, 2021

Research paper thumbnail of The Association Between Perioperative Point-of-Care Platelet Function Analyses and Transfusion Requirements in Cardiac Surgery: Methodological Considerations

The Thoracic and Cardiovascular Surgeon, 2021

Research paper thumbnail of A new approach for open surgery on the abdominal aorta and iliac blood vessels – Piljic Method

Health and primary care, 2021

Research paper thumbnail of Postoperative infection and sepsis in patients following major cardiac surgery

Research paper thumbnail of Rupture of a giant abdominal aortic aneurysm

Journal of Cardiothoracic Surgery, 2013

Research paper thumbnail of A Giant Internal Iliac Artery Aneurysm with Arteriovenous Fistulization

Current Medical Imaging Formerly Current Medical Imaging Reviews, 2020

Background: Isolated iliac artery aneurysms are rare and occur predominantly in men at an older a... more Background: Isolated iliac artery aneurysms are rare and occur predominantly in men at an older age. Such aneurysms can rupture into an adjacent organ (such as the bowel, bladder or ureter) or into the adjacent common iliac vein, resulting in an arteriovenous fistula. INTRODUCTION: Formation of an internal iliac arteriovenous fistula caused by spontaneous rupture of an atherosclerotic iliac artery aneurysm wall is an exceedingly rare yet serious complication. Methods / Results: This article presents a case of an internal iliac arteriovenous fistula caused by rupture of an atherosclerotic giant iliac artery aneurysm. Conclusion: Rapid diagnosis and meticulous surgical technique improve outcomes in patients with this rare vascular complication.

Research paper thumbnail of Restrictive versus Standard Fluid Regimen in Elective Minilaparotomy Abdominal Aortic Repair—Prospective Randomized Controlled Trial

The thoracic and cardiovascular surgeon, Mar 31, 2015

Objective Elective minilaparotomy abdominal aortic aneurysm (AAA) repair is associated with a sig... more Objective Elective minilaparotomy abdominal aortic aneurysm (AAA) repair is associated with a significant number of complications involving respiratory, cardiovascular, gastrointestinal, and central nervous systems, with mortality ranging up to 5%. In our study, we tested the hypothesis that intra- and postoperative intravenous restrictive fluid regimen reduces postoperative morbidity and mortality, and improves the outcome of minilaparotomy AAA repair. Methods From March 2009 to July 2013, 60 patients operated due to AAA were included in a prospective randomized controlled trial (RCT). About the administration of fluid during the operation and in the early postoperative period, all the patients were randomized into two groups: the group of standard fluid administration (S-group, 30 patients) and the group of reduced fluid administration (R-group, 30 patients). The verification of the treatment success was measured by the length of intensive care unit (ICU) stay, duration of hospitalization after the procedure, as well as the number and type of postoperative complications and mortality. This prospective RCT was registered in a publicly accessible database ClinicalTrials.gov with unique Identifier ID: NTC01939652. Results Total fluid administration and administration of blood products were significantly lower in R-group as compared with S-group (2,445.5 mL vs. 3308.7 mL, p = 0.004). Though the number of nonlethal complications was significantly lower in R-group (2 vs. 9 patients, p = 0.042), the difference in lethal complications remained nonsignificant (0 vs. 1 patient, p = ns). The average ICU stay (1.2 vs. 1.97 days, p = 0.003) and duration of postoperative hospital stay (4.33 vs. 6.20 days, p = 0.035 for R-group and S-group, respectively) were found to be significantly shorter in R-group. Conclusion Intra- and postoperative restrictive intravenous fluid regimen in patients undergoing minilaparotomy AAA repair significantly reduces postoperative morbidity, and shortens ICU and overall hospital stay. Even though incidence of lethal complication was lower in R-group, the difference did not reach statistical significance. Therefore, we may assume that this study was probably underpowered to estimate the differences in mortality between R- and S-groups. Further multicentric, sufficiently powered RCTs are needed to confirm these findings and to clarify effect of restrictive fluid management on mortality.

Research paper thumbnail of Giant ruptured abdominal aortic aneurysm

A 76-year-old male with a medical history of smoking and hypertension was admitted to our clinic ... more A 76-year-old male with a medical history of smoking and hypertension was admitted to our clinic with a ruptured abdominal aortic aneurysm (AAA) diagnosed by a trans-abdominal ultrasound. He was immediately brought to the emergency room (ER). His blood pressure was 80/40 mm Hg, with an HTC of less than 0.17. Six years earlier, he had noticed a painless, enlarging abdominal mass. An emergency abdominal computed tomographic angiography (CTA) with intravenous contrast showed a giant infrarenal AAA measuring 13x11 cm in diameter, with clear evidence of rupture and a large intra-abdominal hematoma (Figure 1). He was immediately brought to the operating theater (OT). The approach to the abdomen was a classic median laparotomy. After we had opened the abdomen, we found a huge retroperitoneal hematoma that pushed

Research paper thumbnail of Antimikrobna rezistencija uzročnika izvanbolničkih infekcija mokraćnog sustava u odraslih bolesnika hospitaliziranih u Klinici za infektivne bolesti Tuzla

Research paper thumbnail of A new approach for open surgery on the abdominal aorta and iliac blood vessels – Piljic Method

Research paper thumbnail of Giant ruptured abdominal aortic aneurysm

Saudi Medical Journal, 2014

A 76-year-old male with a medical history of smoking and hypertension was admitted to our clinic ... more A 76-year-old male with a medical history of smoking and hypertension was admitted to our clinic with a ruptured abdominal aortic aneurysm (AAA) diagnosed by a trans-abdominal ultrasound. He was immediately brought to the emergency room (ER). His blood pressure was 80/40 mm Hg, with an HTC of less than 0.17. Six years earlier, he had noticed a painless, enlarging abdominal mass. An emergency abdominal computed tomographic angiography (CTA) with intravenous contrast showed a giant infrarenal AAA measuring 13x11 cm in diameter, with clear evidence of rupture and a large intra-abdominal hematoma (Figure 1). He was immediately brought to the operating theater (OT). Figure 1 Abdominal computed tomographic angiography with contrast showing: A) a ruptured giant abdominal aortic aneurysm (AAA), measuring 13x11 cm with B) a large inta-abdominal hematoma, that compresses the intra-abdominal organs. C) and D) showing a ruptured ... The approach to the abdomen was a classic median laparotomy. A...

Research paper thumbnail of Autologous Arteriovenous Fistula Creation for Haemodialysis in Small Children

Research paper thumbnail of Giant Femoral Artery Pseudoaneurysm Diagnosed 25 Years after War Injury

Research paper thumbnail of A Giant Brachial Artery Pseudoaneurysm in an Infant Boy

Dragan Piljic1, Alen S. Hajdarevic1, Dilista Piljic2, Haris Vukas3, Fahrudin Sabanovic4, Mate Pet... more Dragan Piljic1, Alen S. Hajdarevic1, Dilista Piljic2, Haris Vukas3, Fahrudin Sabanovic4, Mate Petričevic5 and Gordan Samoukovic6 1University Clinical Center Tuzla, Cardiovascular Surgery Clinic, Tuzla, Bosnia and Herzegovina 2University Clinical Center Tuzla, Tuzla, Bosnia and Herzegovina 3Cantonal Hospital Zenica, Zenica, Bosnia and Herzegovina 4Health Care Center Zenica, Zenica, Bosnia and Herzegovina 5University Hospital Center Zagreb, Zagreb, Croatia 6McGill University Montreal, Montreal, Canada

Research paper thumbnail of Biočina B. (2015) Development of a concept for a personalized approach in the perioperative antiplatelet therapy administration/discontinuation management based on multiple electrode aggregometry in patients undergoing coronary artery

Petričević M., Miličić D., White A., Boban M., Zrno Mihaljević M., Piljić D., Rotim A., Buča A., ... more Petričević M., Miličić D., White A., Boban M., Zrno Mihaljević M., Piljić D., Rotim A., Buča A., Mihalj M., Biočina B. (2015) Development of a concept for a personalized approach in the perioperative antiplatelet therapy administration/discontinuation management based on multiple electrode aggregometry in patients undergoing coronary artery surgery. Journal of Thrombosis and Thrombolysis, 40 (3). pp. 383-91. ISSN 0929-5305

Research paper thumbnail of Challenges in diabetic foot treatment during pandemic of COVID-19

Saudi Medical Journal, 2021

Objectives: To avoid hospital spread of Coronavirus-2019 (COVID-19) and to analyze out of hospita... more Objectives: To avoid hospital spread of Coronavirus-2019 (COVID-19) and to analyze out of hospital outcomes after amputation. Methods: Prospective analysis of data obtained from 60 diabetic patients in 2020 was performed at Cantonal Hospital Zenica, Zenica, Bosnia and Herzegovina. Personal protection equipment included double surgical mask, glasses, disposable surgical coats, and surgical masks for patients. Swabs were used to take samples from wounds. We randomly divided patients in 2 groups of 30 patients each. In pre-operative treatment, we used local anesthesia lidocaine hydrochloride 2% (Belupo, Koprivnica, Croatia) in group A and systemic analgesia intravenous tramadol chloride 100 mg intravenous (Krka, Novo Mesto, Slovenia) in group B. Wounds were surgically treated each day and heal spontaneously. Periodical control exams were performed. Results: Wound healing did not present any statistically significant differences between groups (group A: 69±21.97 and B: 61±22.13 days, t=...

Research paper thumbnail of A successful repair of a ruptured giant abdominal aortic aneurysm

Health and Primary Care

Leishmaniasis is a disease caused by Leishmania parasitic protozoans affecting people in both the... more Leishmaniasis is a disease caused by Leishmania parasitic protozoans affecting people in both the Eastern and Western Hemispheres. The secreted acid phosphatase enzymes (SAPs) are reported to play a critical role in infection by Leishmania. Thus, these enzymes are potential targets for Leishmania therapy. Tryptamines have various physiological effects and thus serve different purposes socially. Tryptamines are used in ritualistic ceremonies in countries where Leishmania cases are reported. In this work, tryptamine and two other indole derivatives, harmine and harmaline, were investigated. Harmine and harmaline were selected because of their presence in the biological materials used in some South American ritualistic ceremonies. We investigated the effects on axenic Leishmania tarentolae cell shape, motility, clumping, and viability as well as on the activity of secreted acid phosphatase (SAP) from L. tarentolae. An overall decrease in cell viability over a seven-day period and a small recovery in cell viability, only at lower concentrations of test compounds, were observed. These compounds were, in general, activators of L. tarentolae SAP activity. This is the first report of effects of these compounds on Leishmania secreted acid phosphatase activity in vitro. We speculate that those with Leishmania infections may be worsening their condition with the exposure to these compounds.

Research paper thumbnail of Clinical and Laboratory Characteristics of Acute Community-Acquired Urinary Tract Infections in Adult Hospitalised Patients

Bosnian Journal of Basic Medical Sciences, Feb 20, 2010

Research paper thumbnail of Giant Femoral Artery Pseudoaneurysm Diagnosed 25 Years after War Injury

Journal of biomedical research & environmental sciences, Feb 26, 2019

Research paper thumbnail of The Association Between Perioperative Point-of-Care Platelet Function Analyses and Transfusion Requirements in Cardiac Surgery: Methodological Considerations

Thoracic and Cardiovascular Surgeon, Feb 18, 2021

Research paper thumbnail of Challenges in diabetic foot treatment during pandemic of COVID-19

Saudi Medical Journal, Feb 1, 2021

Research paper thumbnail of The Association Between Perioperative Point-of-Care Platelet Function Analyses and Transfusion Requirements in Cardiac Surgery: Methodological Considerations

The Thoracic and Cardiovascular Surgeon, 2021

Research paper thumbnail of A new approach for open surgery on the abdominal aorta and iliac blood vessels – Piljic Method

Health and primary care, 2021

Research paper thumbnail of Postoperative infection and sepsis in patients following major cardiac surgery

Research paper thumbnail of Rupture of a giant abdominal aortic aneurysm

Journal of Cardiothoracic Surgery, 2013

Research paper thumbnail of A Giant Internal Iliac Artery Aneurysm with Arteriovenous Fistulization

Current Medical Imaging Formerly Current Medical Imaging Reviews, 2020

Background: Isolated iliac artery aneurysms are rare and occur predominantly in men at an older a... more Background: Isolated iliac artery aneurysms are rare and occur predominantly in men at an older age. Such aneurysms can rupture into an adjacent organ (such as the bowel, bladder or ureter) or into the adjacent common iliac vein, resulting in an arteriovenous fistula. INTRODUCTION: Formation of an internal iliac arteriovenous fistula caused by spontaneous rupture of an atherosclerotic iliac artery aneurysm wall is an exceedingly rare yet serious complication. Methods / Results: This article presents a case of an internal iliac arteriovenous fistula caused by rupture of an atherosclerotic giant iliac artery aneurysm. Conclusion: Rapid diagnosis and meticulous surgical technique improve outcomes in patients with this rare vascular complication.

Research paper thumbnail of Restrictive versus Standard Fluid Regimen in Elective Minilaparotomy Abdominal Aortic Repair—Prospective Randomized Controlled Trial

The thoracic and cardiovascular surgeon, Mar 31, 2015

Objective Elective minilaparotomy abdominal aortic aneurysm (AAA) repair is associated with a sig... more Objective Elective minilaparotomy abdominal aortic aneurysm (AAA) repair is associated with a significant number of complications involving respiratory, cardiovascular, gastrointestinal, and central nervous systems, with mortality ranging up to 5%. In our study, we tested the hypothesis that intra- and postoperative intravenous restrictive fluid regimen reduces postoperative morbidity and mortality, and improves the outcome of minilaparotomy AAA repair. Methods From March 2009 to July 2013, 60 patients operated due to AAA were included in a prospective randomized controlled trial (RCT). About the administration of fluid during the operation and in the early postoperative period, all the patients were randomized into two groups: the group of standard fluid administration (S-group, 30 patients) and the group of reduced fluid administration (R-group, 30 patients). The verification of the treatment success was measured by the length of intensive care unit (ICU) stay, duration of hospitalization after the procedure, as well as the number and type of postoperative complications and mortality. This prospective RCT was registered in a publicly accessible database ClinicalTrials.gov with unique Identifier ID: NTC01939652. Results Total fluid administration and administration of blood products were significantly lower in R-group as compared with S-group (2,445.5 mL vs. 3308.7 mL, p = 0.004). Though the number of nonlethal complications was significantly lower in R-group (2 vs. 9 patients, p = 0.042), the difference in lethal complications remained nonsignificant (0 vs. 1 patient, p = ns). The average ICU stay (1.2 vs. 1.97 days, p = 0.003) and duration of postoperative hospital stay (4.33 vs. 6.20 days, p = 0.035 for R-group and S-group, respectively) were found to be significantly shorter in R-group. Conclusion Intra- and postoperative restrictive intravenous fluid regimen in patients undergoing minilaparotomy AAA repair significantly reduces postoperative morbidity, and shortens ICU and overall hospital stay. Even though incidence of lethal complication was lower in R-group, the difference did not reach statistical significance. Therefore, we may assume that this study was probably underpowered to estimate the differences in mortality between R- and S-groups. Further multicentric, sufficiently powered RCTs are needed to confirm these findings and to clarify effect of restrictive fluid management on mortality.

Research paper thumbnail of Giant ruptured abdominal aortic aneurysm

A 76-year-old male with a medical history of smoking and hypertension was admitted to our clinic ... more A 76-year-old male with a medical history of smoking and hypertension was admitted to our clinic with a ruptured abdominal aortic aneurysm (AAA) diagnosed by a trans-abdominal ultrasound. He was immediately brought to the emergency room (ER). His blood pressure was 80/40 mm Hg, with an HTC of less than 0.17. Six years earlier, he had noticed a painless, enlarging abdominal mass. An emergency abdominal computed tomographic angiography (CTA) with intravenous contrast showed a giant infrarenal AAA measuring 13x11 cm in diameter, with clear evidence of rupture and a large intra-abdominal hematoma (Figure 1). He was immediately brought to the operating theater (OT). The approach to the abdomen was a classic median laparotomy. After we had opened the abdomen, we found a huge retroperitoneal hematoma that pushed

Research paper thumbnail of Antimikrobna rezistencija uzročnika izvanbolničkih infekcija mokraćnog sustava u odraslih bolesnika hospitaliziranih u Klinici za infektivne bolesti Tuzla

Research paper thumbnail of A new approach for open surgery on the abdominal aorta and iliac blood vessels – Piljic Method

Research paper thumbnail of Giant ruptured abdominal aortic aneurysm

Saudi Medical Journal, 2014

A 76-year-old male with a medical history of smoking and hypertension was admitted to our clinic ... more A 76-year-old male with a medical history of smoking and hypertension was admitted to our clinic with a ruptured abdominal aortic aneurysm (AAA) diagnosed by a trans-abdominal ultrasound. He was immediately brought to the emergency room (ER). His blood pressure was 80/40 mm Hg, with an HTC of less than 0.17. Six years earlier, he had noticed a painless, enlarging abdominal mass. An emergency abdominal computed tomographic angiography (CTA) with intravenous contrast showed a giant infrarenal AAA measuring 13x11 cm in diameter, with clear evidence of rupture and a large intra-abdominal hematoma (Figure 1). He was immediately brought to the operating theater (OT). Figure 1 Abdominal computed tomographic angiography with contrast showing: A) a ruptured giant abdominal aortic aneurysm (AAA), measuring 13x11 cm with B) a large inta-abdominal hematoma, that compresses the intra-abdominal organs. C) and D) showing a ruptured ... The approach to the abdomen was a classic median laparotomy. A...

Research paper thumbnail of Autologous Arteriovenous Fistula Creation for Haemodialysis in Small Children

Research paper thumbnail of Giant Femoral Artery Pseudoaneurysm Diagnosed 25 Years after War Injury

Research paper thumbnail of A Giant Brachial Artery Pseudoaneurysm in an Infant Boy

Dragan Piljic1, Alen S. Hajdarevic1, Dilista Piljic2, Haris Vukas3, Fahrudin Sabanovic4, Mate Pet... more Dragan Piljic1, Alen S. Hajdarevic1, Dilista Piljic2, Haris Vukas3, Fahrudin Sabanovic4, Mate Petričevic5 and Gordan Samoukovic6 1University Clinical Center Tuzla, Cardiovascular Surgery Clinic, Tuzla, Bosnia and Herzegovina 2University Clinical Center Tuzla, Tuzla, Bosnia and Herzegovina 3Cantonal Hospital Zenica, Zenica, Bosnia and Herzegovina 4Health Care Center Zenica, Zenica, Bosnia and Herzegovina 5University Hospital Center Zagreb, Zagreb, Croatia 6McGill University Montreal, Montreal, Canada

Research paper thumbnail of Biočina B. (2015) Development of a concept for a personalized approach in the perioperative antiplatelet therapy administration/discontinuation management based on multiple electrode aggregometry in patients undergoing coronary artery

Petričević M., Miličić D., White A., Boban M., Zrno Mihaljević M., Piljić D., Rotim A., Buča A., ... more Petričević M., Miličić D., White A., Boban M., Zrno Mihaljević M., Piljić D., Rotim A., Buča A., Mihalj M., Biočina B. (2015) Development of a concept for a personalized approach in the perioperative antiplatelet therapy administration/discontinuation management based on multiple electrode aggregometry in patients undergoing coronary artery surgery. Journal of Thrombosis and Thrombolysis, 40 (3). pp. 383-91. ISSN 0929-5305

Research paper thumbnail of Challenges in diabetic foot treatment during pandemic of COVID-19

Saudi Medical Journal, 2021

Objectives: To avoid hospital spread of Coronavirus-2019 (COVID-19) and to analyze out of hospita... more Objectives: To avoid hospital spread of Coronavirus-2019 (COVID-19) and to analyze out of hospital outcomes after amputation. Methods: Prospective analysis of data obtained from 60 diabetic patients in 2020 was performed at Cantonal Hospital Zenica, Zenica, Bosnia and Herzegovina. Personal protection equipment included double surgical mask, glasses, disposable surgical coats, and surgical masks for patients. Swabs were used to take samples from wounds. We randomly divided patients in 2 groups of 30 patients each. In pre-operative treatment, we used local anesthesia lidocaine hydrochloride 2% (Belupo, Koprivnica, Croatia) in group A and systemic analgesia intravenous tramadol chloride 100 mg intravenous (Krka, Novo Mesto, Slovenia) in group B. Wounds were surgically treated each day and heal spontaneously. Periodical control exams were performed. Results: Wound healing did not present any statistically significant differences between groups (group A: 69±21.97 and B: 61±22.13 days, t=...

Research paper thumbnail of A successful repair of a ruptured giant abdominal aortic aneurysm

Health and Primary Care

Leishmaniasis is a disease caused by Leishmania parasitic protozoans affecting people in both the... more Leishmaniasis is a disease caused by Leishmania parasitic protozoans affecting people in both the Eastern and Western Hemispheres. The secreted acid phosphatase enzymes (SAPs) are reported to play a critical role in infection by Leishmania. Thus, these enzymes are potential targets for Leishmania therapy. Tryptamines have various physiological effects and thus serve different purposes socially. Tryptamines are used in ritualistic ceremonies in countries where Leishmania cases are reported. In this work, tryptamine and two other indole derivatives, harmine and harmaline, were investigated. Harmine and harmaline were selected because of their presence in the biological materials used in some South American ritualistic ceremonies. We investigated the effects on axenic Leishmania tarentolae cell shape, motility, clumping, and viability as well as on the activity of secreted acid phosphatase (SAP) from L. tarentolae. An overall decrease in cell viability over a seven-day period and a small recovery in cell viability, only at lower concentrations of test compounds, were observed. These compounds were, in general, activators of L. tarentolae SAP activity. This is the first report of effects of these compounds on Leishmania secreted acid phosphatase activity in vitro. We speculate that those with Leishmania infections may be worsening their condition with the exposure to these compounds.