Dr. surendra Sonwane - Academia.edu (original) (raw)
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Papers by Dr. surendra Sonwane
Journal of the Serbian Chemical Society, 2012
A new series of N-[2-(2-aminothiazolyl)ethyl]-4-(substitutedphenyl)- 3-chloro-2-oxo-1-iminoazetid... more A new series of N-[2-(2-aminothiazolyl)ethyl]-4-(substitutedphenyl)- 3-chloro-2-oxo-1-iminoazetidine, compounds 4(a-m) have been synthesized from 2-aminothiazole as a starting material. The structure of all the synthesized compounds were confirmed by chemical and spectral analyses such as IR, 1H NMR, 13C NMR and FAB-Mass. All the final synthesized compounds 4(a-m) were screened for their antibacterial and antifungal activities against some selected bacteria and fungi and antitubercular activity screened against M. tuberculosis with their MIC value. Antiinflammatory activity screened against albino rats (either sex) and gave acceptable results.
Heterocyclic chemistry offers an example for the lack of distinct demarcations; in fact, it perva... more Heterocyclic chemistry offers an example for the lack of distinct demarcations; in fact, it pervades the plurality of the other chemical disciplines. Heterocycles are inextricably woven into the life processes. The vital interest of the pharmaceutical and agrochemical industries in heterocycles is often connected with their natural occurrence. A series of 1, 3, 5-triazines derivatives were designed, synthesized and evaluated their biological activity. The preliminary investigation showed that most compounds displayed well to excellent potency against selected micro organism. The structure of the novel compounds was elucidated on the basis of IR, 1 H-NMR and elemental analysis.
Journal of the Serbian Chemical Society, 2012
A new series of N-[2-(2-aminothiazolyl)ethyl]-4-(substitutedphenyl)- 3-chloro-2-oxo-1-iminoazetid... more A new series of N-[2-(2-aminothiazolyl)ethyl]-4-(substitutedphenyl)- 3-chloro-2-oxo-1-iminoazetidine, compounds 4(a-m) have been synthesized from 2-aminothiazole as a starting material. The structure of all the synthesized compounds were confirmed by chemical and spectral analyses such as IR, 1H NMR, 13C NMR and FAB-Mass. All the final synthesized compounds 4(a-m) were screened for their antibacterial and antifungal activities against some selected bacteria and fungi and antitubercular activity screened against M. tuberculosis with their MIC value. Antiinflammatory activity screened against albino rats (either sex) and gave acceptable results.
Heterocyclic chemistry offers an example for the lack of distinct demarcations; in fact, it perva... more Heterocyclic chemistry offers an example for the lack of distinct demarcations; in fact, it pervades the plurality of the other chemical disciplines. Heterocycles are inextricably woven into the life processes. The vital interest of the pharmaceutical and agrochemical industries in heterocycles is often connected with their natural occurrence. A series of 1, 3, 5-triazines derivatives were designed, synthesized and evaluated their biological activity. The preliminary investigation showed that most compounds displayed well to excellent potency against selected micro organism. The structure of the novel compounds was elucidated on the basis of IR, 1 H-NMR and elemental analysis.