Dunia Waked - Academia.edu (original) (raw)
Papers by Dunia Waked
Animal Reproduction Science
Current Opinion in Environmental Science & Health
Neurochemistry International
Epidemiological and toxicological studies have shown that inhalation of particulate matter (PM) i... more Epidemiological and toxicological studies have shown that inhalation of particulate matter (PM) is associated with development of cardiovascular diseases. Long-term exposure to PM may increase the risk of cardiovascular events and reduce life expectancy. Systemic lupus erythematosus (SLE) is a chronic inflammatory disease with autoimmune nature, characterized by the production of autoantibodies that affects several organs, including the heart. Caused by several factors, air pollution, may appear as one of the most important points on the onset and development of SLE. This study aims to investigate whether exposure to air pollution promotes increased inflammation and cardiac remodeling in animals predisposed to SLE. Female mice of NZBWF1, were used in an environmental particle concentrator. Aspects related to cardiac remodeling, inflammation and apoptosis in myocardium were analyzed. Body weight gain, cardiac trophism by heart/body weight ratio, relative area of cardiomyocytes and fi...
Toxics
Nowadays, a large amount and variety of plastic is being produced and consumed by human beings on... more Nowadays, a large amount and variety of plastic is being produced and consumed by human beings on an enormous scale. Microplastics and nanoplastics (MNPLs) have become ubiquitous since they can be found in many ecosystem components. Plastic particles can be found in soil, water, and air. The routes of human exposure are numerous, mainly involving ingestion and inhalation. Once ingested, these particles interact with the gastrointestinal tract and digestive fluids. They can adsorb substances such as additives, heavy metals, proteins, or even microorganisms on their surface, which can cause toxicity. During inhalation, they can be inhaled according to their respective sizes. Studies have reported that exposure to MNPLs can cause damage to the respiratory tract, creating problems such as bronchitis, asthma, fibrosis, and pneumothorax. The reports of boards and committees indicate that there is little data published and available on the toxicity of MNPLs as well as the exposure levels i...
Jornal de Pediatria, 2021
OBJECTIVE In this brief review, the authors focus on the effects of gestational exposures to urba... more OBJECTIVE In this brief review, the authors focus on the effects of gestational exposures to urban air pollution on fetal development and neonatal outcomes. SOURCE OF DATA In this review the authors used PubMed, Web of Science and SciELO research platforms, analyzing papers from the last 30 years. SUMMARY OF THE FINDINGS Epidemiological and experimental evidence agree that gestational exposure to air pollution in urban increases the risks for low birth weight, preterm birth, congenital malformation, intrauterine growth restriction, and neonatal mortality. Furthermore, exposures are associated with increased risks for preeclampsia, hypertension, gestational diabetes. CONCLUSIONS Therefore, it is time for greater involvement and engagement of the health sector in the discussion of public policies that may affect the quality of the environment, and that directly or indirectly impact the health of those who were not yet born.
The disease caused by the SARS-CoV-2 virus, which originated in Wuhan, Hubei Province, China, in ... more The disease caused by the SARS-CoV-2 virus, which originated in Wuhan, Hubei Province, China, in December 2019 spread rapidly, causing a high number of deaths worldwide. The difficult ability to contain the transmission of the disease raised doubts about the possible forms of contamination. Studies have shown an increase in new cases of the disease on days when the level of pollution was high, raising questions that pollutants may be carriers of the virus. In this study, we investigated the involvement of fine particulate matter (PM2.5) in virus loading in common circulation (indoor and outdoor) environments and in the intensive care unit (ICU) of a hospital. PM2.5 was collected from May to November 2020, and the collection time per day was 48 to 72 h. After collection, the material was stored at a temperature of -80°C until the moment of analysis. Our results demonstrated that SARS-CoV-2 can be found in fine particulate material (PM2.5), but there is an essential interference of te...
Toxics
Nowadays, a large amount and variety of plastic is being produced and consumed by human beings on... more Nowadays, a large amount and variety of plastic is being produced and consumed by human beings on an enormous scale. Microplastics and nanoplastics (MNPLs) have become ubiquitous since they can be found in many ecosystem components. Plastic particles can be found in soil, water, and air. The routes of human exposure are numerous, mainly involving ingestion and inhalation. Once ingested, these particles interact with the gastrointestinal tract and digestive fluids. They can adsorb substances such as additives, heavy metals, proteins, or even microorganisms on their surface, which can cause toxicity. During inhalation, they can be inhaled according to their respective sizes. Studies have reported that exposure to MNPLs can cause damage to the respiratory tract, creating problems such as bronchitis, asthma, fibrosis, and pneumothorax. The reports of boards and committees indicate that there is little data published and available on the toxicity of MNPLs as well as the exposure levels i...
Animal Reproduction Science
Current Opinion in Environmental Science & Health
Neurochemistry International
Epidemiological and toxicological studies have shown that inhalation of particulate matter (PM) i... more Epidemiological and toxicological studies have shown that inhalation of particulate matter (PM) is associated with development of cardiovascular diseases. Long-term exposure to PM may increase the risk of cardiovascular events and reduce life expectancy. Systemic lupus erythematosus (SLE) is a chronic inflammatory disease with autoimmune nature, characterized by the production of autoantibodies that affects several organs, including the heart. Caused by several factors, air pollution, may appear as one of the most important points on the onset and development of SLE. This study aims to investigate whether exposure to air pollution promotes increased inflammation and cardiac remodeling in animals predisposed to SLE. Female mice of NZBWF1, were used in an environmental particle concentrator. Aspects related to cardiac remodeling, inflammation and apoptosis in myocardium were analyzed. Body weight gain, cardiac trophism by heart/body weight ratio, relative area of cardiomyocytes and fi...
Toxics
Nowadays, a large amount and variety of plastic is being produced and consumed by human beings on... more Nowadays, a large amount and variety of plastic is being produced and consumed by human beings on an enormous scale. Microplastics and nanoplastics (MNPLs) have become ubiquitous since they can be found in many ecosystem components. Plastic particles can be found in soil, water, and air. The routes of human exposure are numerous, mainly involving ingestion and inhalation. Once ingested, these particles interact with the gastrointestinal tract and digestive fluids. They can adsorb substances such as additives, heavy metals, proteins, or even microorganisms on their surface, which can cause toxicity. During inhalation, they can be inhaled according to their respective sizes. Studies have reported that exposure to MNPLs can cause damage to the respiratory tract, creating problems such as bronchitis, asthma, fibrosis, and pneumothorax. The reports of boards and committees indicate that there is little data published and available on the toxicity of MNPLs as well as the exposure levels i...
Jornal de Pediatria, 2021
OBJECTIVE In this brief review, the authors focus on the effects of gestational exposures to urba... more OBJECTIVE In this brief review, the authors focus on the effects of gestational exposures to urban air pollution on fetal development and neonatal outcomes. SOURCE OF DATA In this review the authors used PubMed, Web of Science and SciELO research platforms, analyzing papers from the last 30 years. SUMMARY OF THE FINDINGS Epidemiological and experimental evidence agree that gestational exposure to air pollution in urban increases the risks for low birth weight, preterm birth, congenital malformation, intrauterine growth restriction, and neonatal mortality. Furthermore, exposures are associated with increased risks for preeclampsia, hypertension, gestational diabetes. CONCLUSIONS Therefore, it is time for greater involvement and engagement of the health sector in the discussion of public policies that may affect the quality of the environment, and that directly or indirectly impact the health of those who were not yet born.
The disease caused by the SARS-CoV-2 virus, which originated in Wuhan, Hubei Province, China, in ... more The disease caused by the SARS-CoV-2 virus, which originated in Wuhan, Hubei Province, China, in December 2019 spread rapidly, causing a high number of deaths worldwide. The difficult ability to contain the transmission of the disease raised doubts about the possible forms of contamination. Studies have shown an increase in new cases of the disease on days when the level of pollution was high, raising questions that pollutants may be carriers of the virus. In this study, we investigated the involvement of fine particulate matter (PM2.5) in virus loading in common circulation (indoor and outdoor) environments and in the intensive care unit (ICU) of a hospital. PM2.5 was collected from May to November 2020, and the collection time per day was 48 to 72 h. After collection, the material was stored at a temperature of -80°C until the moment of analysis. Our results demonstrated that SARS-CoV-2 can be found in fine particulate material (PM2.5), but there is an essential interference of te...
Toxics
Nowadays, a large amount and variety of plastic is being produced and consumed by human beings on... more Nowadays, a large amount and variety of plastic is being produced and consumed by human beings on an enormous scale. Microplastics and nanoplastics (MNPLs) have become ubiquitous since they can be found in many ecosystem components. Plastic particles can be found in soil, water, and air. The routes of human exposure are numerous, mainly involving ingestion and inhalation. Once ingested, these particles interact with the gastrointestinal tract and digestive fluids. They can adsorb substances such as additives, heavy metals, proteins, or even microorganisms on their surface, which can cause toxicity. During inhalation, they can be inhaled according to their respective sizes. Studies have reported that exposure to MNPLs can cause damage to the respiratory tract, creating problems such as bronchitis, asthma, fibrosis, and pneumothorax. The reports of boards and committees indicate that there is little data published and available on the toxicity of MNPLs as well as the exposure levels i...