Emilija Jasovic-Siveska - Academia.edu (original) (raw)

Papers by Emilija Jasovic-Siveska

The aim of the study is early identification of intrauterine growth restriction (IUGR) and fetus ... more The aim of the study is early identification of intrauterine growth restriction (IUGR) and fetus development using ultrasound (US) method and verifying the Pregnancy Induced Hypertension (PIH) influence on the fetus weight and length. In prospective study, during 2 year, we examined 196 pregnancies, between age 15 and 41 years (25,73  5,77), divided in two groups: 67 pregnancy induced hypertensive patients (group A) and 129 normotensive pregnancises (group B). Results: The first differences between the groups appear in the 26 g.a. especially at HC, FL i AC (p<0.01). The ratio HC/AC showed that 7.46% fetuses from group A are suspecting on IUGR (p<0.05). In 40 g.a. asymmetric type IUGR, has been concluded that in 31.82% pregnancies in group A (p<0.01). All pregnancies in group A in 40 g.a. had third degree of placental maturity and all had olighydramnion. In the group B, amniotic fluid was reduced only in 30.21%. The only parameter that statistically wasn’t different between...

PIH is the most common single etiological factor which is causing fetal intrauterine growth retar... more PIH is the most common single etiological factor which is causing fetal intrauterine growth retardation (IUGR). In 50-70% of fetuses with IUGR exists increased maternal blood pressure. It has been proven that the incidence of IUGR is increasing with gaining weight and hypertension duration. Increased blood pressure is leading to decreasing uteroplacental blood flow, also reduced oxygen flow and food to the fetus causing growth restriction. Popular diagnostic method and fetal monitoring is ultrsonography (US). The basic idea of our research is early identification of eventual intrauterine growth restriction and fetus development using ultrasound method. We examined 196 patients between age 15 and 41 years (average age 25,73 ± 5,77 years), divided in two groups: group A based on 67 pregnancy induced hypertensive patients and group B based on 129 normotensive pregnancises. Real-time scanning was performed using ultrasound unit Simens with convex array of 3,5 MHz. The fetal growth was f...

Pregnancy induced hypertension (PIH) is multisystem disorder, of unknown aetiology, associated wi... more Pregnancy induced hypertension (PIH) is multisystem disorder, of unknown aetiology, associated with raised blood pressure and/or proteinuria, manifested after 20th week of gestation, affecting between 6-30% of the pregnant women. We investigated 300 normotensive (K) and 100 hypertensive pregnant, divided in two subgruops: mild (LP, n=67) and severe (TP, n=33) PIH. Women with multiple births, without valid data on the last menstrual period, valid ultrasonographic measurement and chronic maternal disease were excluded. Based on our study the conclusion could be that PIH is most frequently in young primiparas and adult multiparas, illiterate and women with only primary education. The development of PIH is preceded by urine infections and obesities. In the prediction of PIH the measurement of blood pressure is essential, statistical elaboration showed significant differences between hypertensive and normotensive groups even before pathological increase of systolic and diastolic pressure...

Introduction: PIH is the most common single etiological factor which is causing fetal intrauterin... more Introduction: PIH is the most common single etiological factor which is causing fetal intrauterine growth retardation (IUGR). In 50-70% of fetuses with IUGR exists increased maternal blood pressure. It has been proven that the incidence of IUGR is increasing with gaining weight and hypertension duration. Increased blood pressure is leading to decreasing uteroplacental blood flow, also reduced oxygen flow and food to the fetus causing growth restriction. Popular diagnostic method and fetal monitoring is ultrsonography(US). Aim: The basic idea of our research is early identification of eventual intrauterine growth restriction and fetus development using ultrasound method. Methodology: We examined 196 patients between age 15 and 41 years (average age 25,73  5,77 years), divided in two groups: group A based on 67 pregnancy induced hypertensive patients and group B based on 129 normotensive pregnancises. Real-time scanning was performed using ultrasound unit Simens with convex array of ...

Revista medica de Chile

Background: Worldwide, pre-eclampsia and eclampsia contribute to the death of a pregnant woman ev... more Background: Worldwide, pre-eclampsia and eclampsia contribute to the death of a pregnant woman every three minutes. Aim: To determine the demographic risk factors and values of blood pressure to predict preeclampsia. Material and Methods: Demographic and clinical features of 300 normotensive pregnant women aged 28 ±5 years and 100 preeclamptic women aged 28 ±6 years, were assessed. Women with multiple pregnancies were excluded from the study. Results: Women with less educational attainment had a higher risk of mild and severe preeclampsia. Weight gain during pregnancy in control and pre eclamptic women were 14 ±3 and 20 ±5 kg, respectively (p < 0.01). Women with severe preeclampsia had high significantly shorter gestations then the other two patient groups (p < 0.01). Compared to nor-motensive women, at 6 to 12 weeks of gestation, pre eclamptic women had higher systolic (102 ±7 and 113 ±9 mmHg respectively), diastolic ( 64 ±5 and 74 ±10 mmHg respectively) and mean arterial pre...

Aim of the study: was based on the conclusion that Preeclampsia (PE) is not rare in our obstetric... more Aim of the study: was based on the conclusion that Preeclampsia (PE) is not rare in our obstetric population. The basic idea of our study is: early identification of eventually IUGR and fetus development, placental maturation and amount of amniotic fluid using ultrasound (US) method. The objective of the present study was to evaluate the effect of mild and severe PE on fetal growth and body proportion. We hypothesized that inadequate fetal growth at US examinations would indicate development of PE, with combination of other risk factors. Methodology: Prospective study in a period of 15 months. The research was conducted in the Clinical Hospital ”Dr Trifun Panovski” in Bitola, Macedonia, Department of gynaecology and obstetrics. These patients had been admitted during the period of May 1st 2008 to August 1st 2009. We studied 300 normotensive and 100 PE pregnancies divided into two subgroups: mild (n=67) and severe (n=33) PE. The US scanning was performed using the US unit GE Logiq CX...

Preeclampsia is a common, yet incompletely understood, complication of pregnancy. Women with pree... more Preeclampsia is a common, yet incompletely understood, complication of pregnancy. Women with preeclampsia usually develop hypertension, proteinuria, and varying degrees of ischemic end-organ damage, caused by widespread endothelial dysfunction. Preeclampsia is also associated with abnormalities of coagulation system, disturbed liver function, renal failure and cerebral ischemia [1].

The influence of antepartal, intrapartal and early neonatal risk factors are important for pregna... more The influence of antepartal, intrapartal and early neonatal risk factors are important for pregnancy outcome, the early neonatal period and the forthcoming children development. Our aim is to detect the risk groups of pregnant women who later develop Pregnancy Induced Hypertension (PIH) and the risk factors that precede its appearance as well. The 67 preeclamptic and 129 normotensive pregnancies were examined. The patients had a monthly blood pressure check and regular analysis of blood and urine. Average age was 25.73±5.77 years. Preeclampsia or Pregnancy Induced Hypertension (PIH) is most frequently appearing in young primiparas and adult multiparas. The housewife’s, illiterate women and women with only primary education are the most risky groups. The development of PIH is preceded by recurrent urine infections and/or obesities. In the prediction of PIH the measurement of BP is essential: the statistical elaboration of data showed significant differences between hypertensive and n...

Approximately 4% of all pregnancies are affected by a genetic condition or a major congenital mal... more Approximately 4% of all pregnancies are affected by a genetic condition or a major congenital malformation. Because with rare exceptions there is no effective therapy for these disorders, the only alternative at present is early detection and selective termination. The new FASTER trial, like screening test, combines first and second trimester, including ultrasonographic and serum markers, as well as maternal age. Ultrasound between 10-14 weeks assesses the thickness of the nuchal fold of the developing fetus; this measure is called nuchal translucency (NT), and NT is combined with the PAPP-A and free â-HCG. In the second trimester, ultrasonography is combined with the HCG, á-fetoprotein, unconjugated estriol and inhibin-A levels. The serum markers are performed on maternal serum drawn between 15 and 19 weeks. Finally, an important point to remember is that these new developments augment and enhance the options for screening, but screening tests, no matter how well they perform, are ...

Medicus

Hyperandrogenism is excess androgen production (testosterone, androstenedion or DHEA-S) in female... more Hyperandrogenism is excess androgen production (testosterone, androstenedion or DHEA-S) in female circulation. In the study was included 100 patients divided in 4 groups: group A- 62 patients (PCOS), B-8 patients (late form of CAH), gruop C- 19 patients (idiopathic hirsutism) and group D- 11 (health women). Increased basal serum LH levels were only in group A. LH: FSH index were higher in 42% patients with PCOS. Basal serum levels of PRL were higher in 27% patients with PCOS. Testosterone were increased in patients with PCOS (4.25±1.78 nmol/ml) and late form of CAH (6.02±1.58 nmol/ml) (p<0.01). Levels of DHEA-S was increased in 23,7% patients with PCOS (p>0.05). Average basal 17-OH-P levels for group B ( _ x =37,9 ±16,55noml/l) were 9 time higher versus group D (p<0.01). Average basal serum E2 levels were significantly different into the groups (p<0.01): group A _ x =331,6±200,6pmol/l; group B _ x =177,5±56,97pmol/l; group C _ x =221,6±167,52 pmol/l and group D _ x =301,...

Medicus

The purpose of this paper is to dissolve the dilemmas about the importance of existence a need fo... more The purpose of this paper is to dissolve the dilemmas about the importance of existence a need for organizing continued medical education (CME). CME aims to reduce the inevitable delay in the medical science and implementation of health care, for physicians and for other health professions. Discussion: CME Sun represents learning programmed instruction, but personally, self promotion, or advancement in the personal process of paradigm changes in the ruled. CME is essentially concerned with developing the professional competence of physicians, nurses, midwives, physiotherapists etc., as well as information on developments in medicine, technology, science and care. CME can be performed by: Individual activities, group activities and organized group activity. All these activities are proving to obtained certification where we can note the number of scored points, and that certificate is a confirmation to the chamber (or association) the number of scored points, which are collected a ce...

The Open Access Journal of Science and Technology, 2014

We studied 300 normotensive and 100 PE pregnancies divided into two subgroups: mild ( = 67) and s... more We studied 300 normotensive and 100 PE pregnancies divided into two subgroups: mild ( = 67) and severe ( = 33) PE. This research has included only single pregnancies and the following parameters: maternal age, parity, previous pregnancy history and interval between pregnancies. The study is based on 400 pregnancies with a mean age of 27.65±5.04 years. The significant difference in the frequency of categories and age groups was tested with a method of multivariate analysis for proportion. The difference was not statistically significant > 0.05, which clearly shows that the groups are a priori similar and comparable. Our study shows that PE is most commonly developed in primiparas ( < 0.05). The difference was at the level < 0.001. Among women with no history of PE, the median interbirth interval was 4.24 years between the previous and actual pregnancy. Among women with mild PE the median interbirth interval was 5.96 and in group with severe PE was 8.08 years. Multiparous women who are pregnant 5, especially 10 years or more after their previous pregnancy are as likely to have preeclampsia as nulliparous women.

Bratislavské lekárske listy, 2008

An early identification of eventual intrauterine growth retardation (IUGR) and fetus development ... more An early identification of eventual intrauterine growth retardation (IUGR) and fetus development using an ultrasound method. Preeclampsia (PIH) complicates from 5 to 10% of pregnancies and it is a leading cause of maternal and fetal mortality and morbidity. The study was conducted during a 2 year period based on patients between 15 and 41 years, divided in two groups: group A based on 67 preeclamptic patients, and group B based on 129 normotensive pregnancises. The fetuses from group A were suspected from IUGR (p<0.05). Based on our study it can be concluded that IUGR is the main complication of the fetus in the hypertensive pregnancy. The most common type of restriction in PIH was the asymmetric type of IUGR. In PIH pregnancies, there could be a faster aging of the placenta and oligohydramnion (Tab. 9, Fig. 7, Ref. 20). Full Text (Free, PDF) www.bmj.sk.

Ginekologia polska, 2011

The study was designed to determine the accuracy of using systolic (SBP) and diastolic blood pres... more The study was designed to determine the accuracy of using systolic (SBP) and diastolic blood pressure (DBP), mean arterial pressure (MAP), and increase of blood pressure (BP) to predict Preeclampsia (PE). We examined 300 normotensive and 100 PE pregnancies divided in two subgroups: mild (n = 67) and severe (n = 33) PE. The patients had a BP check in first and second trimester (SBFP DBP and MAP). We found out significant difference between the groups, but what is more important is that the difference in BP values (especially diastolic and MAP) existed before the pathological increase of the BP above the normal values. This was happening most often after 31 wg (at 92.5%) and less often after 26 wg (at 7.5%) at the pregnancies with mild PE while at the pregnancies with severe PE, 18,2% had increased tension after 21 wg; 24% in the period of 26-30 wg and 57.58% after 31 wg. Based on the results we could conclude that when BP is measured in the first or second trimester of pregnancy the ...

Bratislavské lekárske listy, 2011

The influence of antepartal, intrapartal and early neonatal risk factors, are very important duri... more The influence of antepartal, intrapartal and early neonatal risk factors, are very important during the pregnancy and the pregnancy outcome, also for the early neonatal period and the forthcoming children development. Our aim is to detect the risks groups of pregnant women that later develop Pregnancy Induced Hypertension (PIH) and risk factors that precede its appearance. We examined 67 preeclamptic and 129 normotensive pregnancies. In research are included only single pregnancies and the following parameters: maternal age, parity and previous pregnancy history. Average age is 25.73+/-5.77 years. After all, the largest number of primipara with preeclampsia is in category from 20 years (p<0.01). Considering the multipara we noticed that preeclampsia is most commonly developed in age between 31-35 years (p<0.01). Biggest number of pregnancies in normotensive group had previous normal pregnancies (59.15 %), while in hypertensive group only 30.77 % patients had normal pregnancies...

Reproductive System & Sexual Disorders, 2014

Reproductive System & Sexual Disorders, 2013

Vojnosanitetski pregled, 2012

Vojnosanitetskog pregleda izašao je septembra meseca 1944. godine asopis nastavlja tradiciju Vojn... more Vojnosanitetskog pregleda izašao je septembra meseca 1944. godine asopis nastavlja tradiciju Vojno-sanitetskog glasnika, koji je izlazio od 1930. do 1941. godine IZDAVA Uprava za vojno zdravstvo MO Srbije IZDAVA KI SAVET prof. dr sc. med. Boris Ajdinovi prof. dr sc. pharm. Mirjana Antunovi Doc. dr Radovan ekanac, puk. prof. dr sc. med. Dragan Din i , puk. prof. dr sc. med. Zoran Hajdukovi , puk. Prof. dr sc. med. Nebojša Jovi , puk. prof. dr sc. med. Marijan Novakovi , brigadni general prof. dr sc. med. Zoran Popovi , puk. (predsednik) prof. dr sc. med. Predrag Romi , puk. prim. dr Stevan Sikimi , puk.

The aim of the study is early identification of intrauterine growth restriction (IUGR) and fetus ... more The aim of the study is early identification of intrauterine growth restriction (IUGR) and fetus development using ultrasound (US) method and verifying the Pregnancy Induced Hypertension (PIH) influence on the fetus weight and length. In prospective study, during 2 year, we examined 196 pregnancies, between age 15 and 41 years (25,73  5,77), divided in two groups: 67 pregnancy induced hypertensive patients (group A) and 129 normotensive pregnancises (group B). Results: The first differences between the groups appear in the 26 g.a. especially at HC, FL i AC (p<0.01). The ratio HC/AC showed that 7.46% fetuses from group A are suspecting on IUGR (p<0.05). In 40 g.a. asymmetric type IUGR, has been concluded that in 31.82% pregnancies in group A (p<0.01). All pregnancies in group A in 40 g.a. had third degree of placental maturity and all had olighydramnion. In the group B, amniotic fluid was reduced only in 30.21%. The only parameter that statistically wasn’t different between...

PIH is the most common single etiological factor which is causing fetal intrauterine growth retar... more PIH is the most common single etiological factor which is causing fetal intrauterine growth retardation (IUGR). In 50-70% of fetuses with IUGR exists increased maternal blood pressure. It has been proven that the incidence of IUGR is increasing with gaining weight and hypertension duration. Increased blood pressure is leading to decreasing uteroplacental blood flow, also reduced oxygen flow and food to the fetus causing growth restriction. Popular diagnostic method and fetal monitoring is ultrsonography (US). The basic idea of our research is early identification of eventual intrauterine growth restriction and fetus development using ultrasound method. We examined 196 patients between age 15 and 41 years (average age 25,73 ± 5,77 years), divided in two groups: group A based on 67 pregnancy induced hypertensive patients and group B based on 129 normotensive pregnancises. Real-time scanning was performed using ultrasound unit Simens with convex array of 3,5 MHz. The fetal growth was f...

Pregnancy induced hypertension (PIH) is multisystem disorder, of unknown aetiology, associated wi... more Pregnancy induced hypertension (PIH) is multisystem disorder, of unknown aetiology, associated with raised blood pressure and/or proteinuria, manifested after 20th week of gestation, affecting between 6-30% of the pregnant women. We investigated 300 normotensive (K) and 100 hypertensive pregnant, divided in two subgruops: mild (LP, n=67) and severe (TP, n=33) PIH. Women with multiple births, without valid data on the last menstrual period, valid ultrasonographic measurement and chronic maternal disease were excluded. Based on our study the conclusion could be that PIH is most frequently in young primiparas and adult multiparas, illiterate and women with only primary education. The development of PIH is preceded by urine infections and obesities. In the prediction of PIH the measurement of blood pressure is essential, statistical elaboration showed significant differences between hypertensive and normotensive groups even before pathological increase of systolic and diastolic pressure...

Introduction: PIH is the most common single etiological factor which is causing fetal intrauterin... more Introduction: PIH is the most common single etiological factor which is causing fetal intrauterine growth retardation (IUGR). In 50-70% of fetuses with IUGR exists increased maternal blood pressure. It has been proven that the incidence of IUGR is increasing with gaining weight and hypertension duration. Increased blood pressure is leading to decreasing uteroplacental blood flow, also reduced oxygen flow and food to the fetus causing growth restriction. Popular diagnostic method and fetal monitoring is ultrsonography(US). Aim: The basic idea of our research is early identification of eventual intrauterine growth restriction and fetus development using ultrasound method. Methodology: We examined 196 patients between age 15 and 41 years (average age 25,73  5,77 years), divided in two groups: group A based on 67 pregnancy induced hypertensive patients and group B based on 129 normotensive pregnancises. Real-time scanning was performed using ultrasound unit Simens with convex array of ...

Revista medica de Chile

Background: Worldwide, pre-eclampsia and eclampsia contribute to the death of a pregnant woman ev... more Background: Worldwide, pre-eclampsia and eclampsia contribute to the death of a pregnant woman every three minutes. Aim: To determine the demographic risk factors and values of blood pressure to predict preeclampsia. Material and Methods: Demographic and clinical features of 300 normotensive pregnant women aged 28 ±5 years and 100 preeclamptic women aged 28 ±6 years, were assessed. Women with multiple pregnancies were excluded from the study. Results: Women with less educational attainment had a higher risk of mild and severe preeclampsia. Weight gain during pregnancy in control and pre eclamptic women were 14 ±3 and 20 ±5 kg, respectively (p < 0.01). Women with severe preeclampsia had high significantly shorter gestations then the other two patient groups (p < 0.01). Compared to nor-motensive women, at 6 to 12 weeks of gestation, pre eclamptic women had higher systolic (102 ±7 and 113 ±9 mmHg respectively), diastolic ( 64 ±5 and 74 ±10 mmHg respectively) and mean arterial pre...

Aim of the study: was based on the conclusion that Preeclampsia (PE) is not rare in our obstetric... more Aim of the study: was based on the conclusion that Preeclampsia (PE) is not rare in our obstetric population. The basic idea of our study is: early identification of eventually IUGR and fetus development, placental maturation and amount of amniotic fluid using ultrasound (US) method. The objective of the present study was to evaluate the effect of mild and severe PE on fetal growth and body proportion. We hypothesized that inadequate fetal growth at US examinations would indicate development of PE, with combination of other risk factors. Methodology: Prospective study in a period of 15 months. The research was conducted in the Clinical Hospital ”Dr Trifun Panovski” in Bitola, Macedonia, Department of gynaecology and obstetrics. These patients had been admitted during the period of May 1st 2008 to August 1st 2009. We studied 300 normotensive and 100 PE pregnancies divided into two subgroups: mild (n=67) and severe (n=33) PE. The US scanning was performed using the US unit GE Logiq CX...

Preeclampsia is a common, yet incompletely understood, complication of pregnancy. Women with pree... more Preeclampsia is a common, yet incompletely understood, complication of pregnancy. Women with preeclampsia usually develop hypertension, proteinuria, and varying degrees of ischemic end-organ damage, caused by widespread endothelial dysfunction. Preeclampsia is also associated with abnormalities of coagulation system, disturbed liver function, renal failure and cerebral ischemia [1].

The influence of antepartal, intrapartal and early neonatal risk factors are important for pregna... more The influence of antepartal, intrapartal and early neonatal risk factors are important for pregnancy outcome, the early neonatal period and the forthcoming children development. Our aim is to detect the risk groups of pregnant women who later develop Pregnancy Induced Hypertension (PIH) and the risk factors that precede its appearance as well. The 67 preeclamptic and 129 normotensive pregnancies were examined. The patients had a monthly blood pressure check and regular analysis of blood and urine. Average age was 25.73±5.77 years. Preeclampsia or Pregnancy Induced Hypertension (PIH) is most frequently appearing in young primiparas and adult multiparas. The housewife’s, illiterate women and women with only primary education are the most risky groups. The development of PIH is preceded by recurrent urine infections and/or obesities. In the prediction of PIH the measurement of BP is essential: the statistical elaboration of data showed significant differences between hypertensive and n...

Approximately 4% of all pregnancies are affected by a genetic condition or a major congenital mal... more Approximately 4% of all pregnancies are affected by a genetic condition or a major congenital malformation. Because with rare exceptions there is no effective therapy for these disorders, the only alternative at present is early detection and selective termination. The new FASTER trial, like screening test, combines first and second trimester, including ultrasonographic and serum markers, as well as maternal age. Ultrasound between 10-14 weeks assesses the thickness of the nuchal fold of the developing fetus; this measure is called nuchal translucency (NT), and NT is combined with the PAPP-A and free â-HCG. In the second trimester, ultrasonography is combined with the HCG, á-fetoprotein, unconjugated estriol and inhibin-A levels. The serum markers are performed on maternal serum drawn between 15 and 19 weeks. Finally, an important point to remember is that these new developments augment and enhance the options for screening, but screening tests, no matter how well they perform, are ...

Medicus

Hyperandrogenism is excess androgen production (testosterone, androstenedion or DHEA-S) in female... more Hyperandrogenism is excess androgen production (testosterone, androstenedion or DHEA-S) in female circulation. In the study was included 100 patients divided in 4 groups: group A- 62 patients (PCOS), B-8 patients (late form of CAH), gruop C- 19 patients (idiopathic hirsutism) and group D- 11 (health women). Increased basal serum LH levels were only in group A. LH: FSH index were higher in 42% patients with PCOS. Basal serum levels of PRL were higher in 27% patients with PCOS. Testosterone were increased in patients with PCOS (4.25±1.78 nmol/ml) and late form of CAH (6.02±1.58 nmol/ml) (p<0.01). Levels of DHEA-S was increased in 23,7% patients with PCOS (p>0.05). Average basal 17-OH-P levels for group B ( _ x =37,9 ±16,55noml/l) were 9 time higher versus group D (p<0.01). Average basal serum E2 levels were significantly different into the groups (p<0.01): group A _ x =331,6±200,6pmol/l; group B _ x =177,5±56,97pmol/l; group C _ x =221,6±167,52 pmol/l and group D _ x =301,...

Medicus

The purpose of this paper is to dissolve the dilemmas about the importance of existence a need fo... more The purpose of this paper is to dissolve the dilemmas about the importance of existence a need for organizing continued medical education (CME). CME aims to reduce the inevitable delay in the medical science and implementation of health care, for physicians and for other health professions. Discussion: CME Sun represents learning programmed instruction, but personally, self promotion, or advancement in the personal process of paradigm changes in the ruled. CME is essentially concerned with developing the professional competence of physicians, nurses, midwives, physiotherapists etc., as well as information on developments in medicine, technology, science and care. CME can be performed by: Individual activities, group activities and organized group activity. All these activities are proving to obtained certification where we can note the number of scored points, and that certificate is a confirmation to the chamber (or association) the number of scored points, which are collected a ce...

The Open Access Journal of Science and Technology, 2014

We studied 300 normotensive and 100 PE pregnancies divided into two subgroups: mild ( = 67) and s... more We studied 300 normotensive and 100 PE pregnancies divided into two subgroups: mild ( = 67) and severe ( = 33) PE. This research has included only single pregnancies and the following parameters: maternal age, parity, previous pregnancy history and interval between pregnancies. The study is based on 400 pregnancies with a mean age of 27.65±5.04 years. The significant difference in the frequency of categories and age groups was tested with a method of multivariate analysis for proportion. The difference was not statistically significant > 0.05, which clearly shows that the groups are a priori similar and comparable. Our study shows that PE is most commonly developed in primiparas ( < 0.05). The difference was at the level < 0.001. Among women with no history of PE, the median interbirth interval was 4.24 years between the previous and actual pregnancy. Among women with mild PE the median interbirth interval was 5.96 and in group with severe PE was 8.08 years. Multiparous women who are pregnant 5, especially 10 years or more after their previous pregnancy are as likely to have preeclampsia as nulliparous women.

Bratislavské lekárske listy, 2008

An early identification of eventual intrauterine growth retardation (IUGR) and fetus development ... more An early identification of eventual intrauterine growth retardation (IUGR) and fetus development using an ultrasound method. Preeclampsia (PIH) complicates from 5 to 10% of pregnancies and it is a leading cause of maternal and fetal mortality and morbidity. The study was conducted during a 2 year period based on patients between 15 and 41 years, divided in two groups: group A based on 67 preeclamptic patients, and group B based on 129 normotensive pregnancises. The fetuses from group A were suspected from IUGR (p<0.05). Based on our study it can be concluded that IUGR is the main complication of the fetus in the hypertensive pregnancy. The most common type of restriction in PIH was the asymmetric type of IUGR. In PIH pregnancies, there could be a faster aging of the placenta and oligohydramnion (Tab. 9, Fig. 7, Ref. 20). Full Text (Free, PDF) www.bmj.sk.

Ginekologia polska, 2011

The study was designed to determine the accuracy of using systolic (SBP) and diastolic blood pres... more The study was designed to determine the accuracy of using systolic (SBP) and diastolic blood pressure (DBP), mean arterial pressure (MAP), and increase of blood pressure (BP) to predict Preeclampsia (PE). We examined 300 normotensive and 100 PE pregnancies divided in two subgroups: mild (n = 67) and severe (n = 33) PE. The patients had a BP check in first and second trimester (SBFP DBP and MAP). We found out significant difference between the groups, but what is more important is that the difference in BP values (especially diastolic and MAP) existed before the pathological increase of the BP above the normal values. This was happening most often after 31 wg (at 92.5%) and less often after 26 wg (at 7.5%) at the pregnancies with mild PE while at the pregnancies with severe PE, 18,2% had increased tension after 21 wg; 24% in the period of 26-30 wg and 57.58% after 31 wg. Based on the results we could conclude that when BP is measured in the first or second trimester of pregnancy the ...

Bratislavské lekárske listy, 2011

The influence of antepartal, intrapartal and early neonatal risk factors, are very important duri... more The influence of antepartal, intrapartal and early neonatal risk factors, are very important during the pregnancy and the pregnancy outcome, also for the early neonatal period and the forthcoming children development. Our aim is to detect the risks groups of pregnant women that later develop Pregnancy Induced Hypertension (PIH) and risk factors that precede its appearance. We examined 67 preeclamptic and 129 normotensive pregnancies. In research are included only single pregnancies and the following parameters: maternal age, parity and previous pregnancy history. Average age is 25.73+/-5.77 years. After all, the largest number of primipara with preeclampsia is in category from 20 years (p<0.01). Considering the multipara we noticed that preeclampsia is most commonly developed in age between 31-35 years (p<0.01). Biggest number of pregnancies in normotensive group had previous normal pregnancies (59.15 %), while in hypertensive group only 30.77 % patients had normal pregnancies...

Reproductive System & Sexual Disorders, 2014

Reproductive System & Sexual Disorders, 2013

Vojnosanitetski pregled, 2012

Vojnosanitetskog pregleda izašao je septembra meseca 1944. godine asopis nastavlja tradiciju Vojn... more Vojnosanitetskog pregleda izašao je septembra meseca 1944. godine asopis nastavlja tradiciju Vojno-sanitetskog glasnika, koji je izlazio od 1930. do 1941. godine IZDAVA Uprava za vojno zdravstvo MO Srbije IZDAVA KI SAVET prof. dr sc. med. Boris Ajdinovi prof. dr sc. pharm. Mirjana Antunovi Doc. dr Radovan ekanac, puk. prof. dr sc. med. Dragan Din i , puk. prof. dr sc. med. Zoran Hajdukovi , puk. Prof. dr sc. med. Nebojša Jovi , puk. prof. dr sc. med. Marijan Novakovi , brigadni general prof. dr sc. med. Zoran Popovi , puk. (predsednik) prof. dr sc. med. Predrag Romi , puk. prim. dr Stevan Sikimi , puk.