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ELIANA ARAUJO

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Research paper thumbnail of Asthma and COVID-19 - A systematic review

Letter to de Editor Asthma and COVID-19-A systematic review Dear Editor, COVID-19 was first repor... more Letter to de Editor Asthma and COVID-19-A systematic review Dear Editor, COVID-19 was first reported in December, 2019 in Wuhan, China, and rapidly spread across the globe 1. It has affected more than 6.4 million people and has led to the death of over 370 thousand as of June 2, 2020 (www.who.org). Severely affected patients present fever, dry cough, dyspnea, and fatigue, which are commonly associated with the development of pneumonia and acute respiratory distress syndrome (ARDS) 2. Advanced age, ischemic and congestive heart disease, hypertension, diabetes, and chronic obstructive pulmonary disease (COPD) are the most important independent predictors of death 2,3. As with other infectious diseases affecting the respiratory tract, asthma has been cited as a potential risk factor for severe COVID-19 4-6 ; however, no previous study has addressed this specific question.

Research paper thumbnail of Additional file 8: Figure S2. of Dietary fats promote functional and structural changes in the median eminence blood/spinal fluid interface—the protective role for BDNF

Evaluation of the blood-brain barrier integrity. The protocol employed for evaluation of BBB inte... more Evaluation of the blood-brain barrier integrity. The protocol employed for evaluation of BBB integrity is shown in Fig. 2a. Confocal microscopy analysis was employed for determining FITC-dextran endogenous fluorescence in the regions of the vascular organ of lamina terminalis (OVLT), subfornical organ (SFO), and subcomissural organ (SCO); in all acquisitions, the same settings of the microscope were employed (laser 488, wavelength = 405, %laser = 20%, gain = 1015, offset = − 0.3799). The fluorescence in the distinct regions was determined using an ImageJ software and presented as relative to control. N = 4. (PDF 141 kb)

Research paper thumbnail of Asthma and COVID-19 - A systematic review

Letter to de Editor Asthma and COVID-19-A systematic review Dear Editor, COVID-19 was first repor... more Letter to de Editor Asthma and COVID-19-A systematic review Dear Editor, COVID-19 was first reported in December, 2019 in Wuhan, China, and rapidly spread across the globe 1. It has affected more than 6.4 million people and has led to the death of over 370 thousand as of June 2, 2020 (www.who.org). Severely affected patients present fever, dry cough, dyspnea, and fatigue, which are commonly associated with the development of pneumonia and acute respiratory distress syndrome (ARDS) 2. Advanced age, ischemic and congestive heart disease, hypertension, diabetes, and chronic obstructive pulmonary disease (COPD) are the most important independent predictors of death 2,3. As with other infectious diseases affecting the respiratory tract, asthma has been cited as a potential risk factor for severe COVID-19 4-6 ; however, no previous study has addressed this specific question.

Research paper thumbnail of Additional file 8: Figure S2. of Dietary fats promote functional and structural changes in the median eminence blood/spinal fluid interface—the protective role for BDNF

Evaluation of the blood-brain barrier integrity. The protocol employed for evaluation of BBB inte... more Evaluation of the blood-brain barrier integrity. The protocol employed for evaluation of BBB integrity is shown in Fig. 2a. Confocal microscopy analysis was employed for determining FITC-dextran endogenous fluorescence in the regions of the vascular organ of lamina terminalis (OVLT), subfornical organ (SFO), and subcomissural organ (SCO); in all acquisitions, the same settings of the microscope were employed (laser 488, wavelength = 405, %laser = 20%, gain = 1015, offset = − 0.3799). The fluorescence in the distinct regions was determined using an ImageJ software and presented as relative to control. N = 4. (PDF 141 kb)

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