E. Mass - Academia.edu (original) (raw)
Papers by E. Mass
Quintessence international, 2005
To investigate the prevalence and severity of a labial-cervical-vertical groove (LCVG) in maxilla... more To investigate the prevalence and severity of a labial-cervical-vertical groove (LCVG) in maxillary permanent incisors and its effect on the associated gingival tissue. A total of 600 adolescents (293 boys and 307 girls, mean age 13.6+/-1.99 years) were randomly selected and examined for the presence of LCVG. The deformity was classified as mild, moderate, or severe according to predetermined criteria. Gingival coverage at the groove site was defined as normal, partial, and irregular. LCVG was found in 27 adolescents (4.5%). It was unilateral in 24 (89%) and bilateral in 3 (11%). The ratio of central to lateral incisors was 29:1. No sexual dimorphism or side prevalence were found. Mild LCVG was found in 22 incisors, moderate LCVG in 7 incisors, and severe LCVG in one incisor. Moderate LCVG was 5 to 6 times more susceptible to partial or irregular coverage of the gingival margin than mild LCVG. The gingival sulcus in teeth with LCVG demonstrated a significant (P = .001) increase in depth compared to non-LCVG teeth (1.55+/-0.90 mm vs 1.18+/-0.75 mm). An LCVG is a deformity confined predominantly to a single permanent maxillary central incisor. Its prevalence is not connected with gender. Most LCVGs are mild and often difficult to detect. However, the greater the severity, the more gingival irregularity is associated. This and the increase in sulcus depth in LCVG incisors are adverse predispositions for periodontal sequelae, calling for cautious oral hygiene maintenance.
Refuʾat ha-peh ṿeha-shinayim (Tel Aviv, Israel : 1969), 1978
Talon cusp is a rare dental anomaly hitherto considered to affect permanent dentition only. A cas... more Talon cusp is a rare dental anomaly hitherto considered to affect permanent dentition only. A case of talon cusp in a deciduous maxillary incisor is described, suggesting that both dentitions may be affected by this anomaly.
Quintessence international (Berlin, Germany : 1985)
Radiographic appearance of pulp reactions to partial pulpotomy in young permanent molars with dee... more Radiographic appearance of pulp reactions to partial pulpotomy in young permanent molars with deep caries may determine the efficiency of the procedure. The objective of this study was to determine the value of this procedure by analyzing the pulpal and periapical appearance of permanent molars after long-term follow-up periods. Based on predetermined radiologic criteria, periapical radiographs of 49 young permanent molars of 31 females and 13 males, aged 6.9 to 17.7 years (mean, 11.4 years) treated with partial pulpotomy were evaluated and compared to their antimeres. Follow-up time ranged from 7 to 154 months (mean, 49 months). Based on clinical and radiographic findings, the success rate was considered 93.9% (46 of 49 teeth). Three teeth had chronic pulpitis with periapical exacerbation. In 14 (30.4%) of the 46 teeth, normal radiographic pulp appearance was found, and in 2 (4.3%), pulpal calcifications were similar to their antimere tooth. Dentinal bridges were observed underneat...
European Journal of Paediatric Dentistry
This was to evaluate some suggested diagnostic procedures, treatment policies and professional at... more This was to evaluate some suggested diagnostic procedures, treatment policies and professional attitudes of specialists in paediatric dentistry, in light of the periodically published guidelines by The American Academy of Pediatric Dentistry, The European Academy of Paediatric Dentistry and The British Society of Paediatric Dentistry. Using a structured questionnaire, 67% of the Israeli specialists in paediatric dentistry, who agreed to participate in this study, were personally interviewed. Only 7.5% of the participants reported that they carry out pulp capping of primary teeth in cases of pulp exposure. Over 50% reported restoring teeth after pulpotomy with preformed crowns. Most indicated sealing pit and fissures after considering depth and morphology of the fissures and correlation with the patient's risk to caries. Cleaning teeth after eruption of the first tooth was suggested by 75.5% of the participants. A striking majority (96%) claimed that they restored permanent anter...
Pediatric dentistry
Extremely low caries rate and increased major salivary gland flow rare have been previously repor... more Extremely low caries rate and increased major salivary gland flow rare have been previously reported in children with familial dysautonomia (FD). The purpose of this study was to explore the possibility that, in addition to increased salivary flow, children with FD have alterations in their salivary components, which may suggest an explanauon to their low caries rate. Whole unstimulated and stimulated saliva samples were collected from 13 children with FD who were found to be caries free, and from 28 age- and ethnic-matched healthy children, 15 caries-free children and 13 caries-affected children. The electrolyte and protein content of the unstimulated saliva and the microbial count and buffering capacity of the stimulated saliva were determined. Children with FD had the highest salivary flow rate and the lowest levels of mutans streptococci and lactobacilli, as well as the lowest concentration of chloride, magnesium, total protein and IgA. Healthy caries-affected children displayed...
ASDC journal of dentistry for children
The aim of the present retrospective study was to observe the clinical and radiographic performan... more The aim of the present retrospective study was to observe the clinical and radiographic performances of a compomer (Dyract) in proximal restorations of primary molars as compared to amalgam restorations. The study was performed at the principal investigator's office. Children between three to eleven years old, who had at least two primary molars with a small to moderate approximal caries lesion were included in the study. The assessed material consisted of 107 proximal restorations (63 Dyract and 44 amalgam) placed in primary molars during the years 1994 to 1997 in forty-two children who were available for follow-up examinations. All the evaluated restorations were clinically acceptable, with smooth surface appearance, satisfactory color match, neither secondary caries nor fracture. The margins of two Dyract restorations presented minimal stain. Of the 63 Dyract restorations evaluated radiographically, two presented with bubbles, one with an overhang, and nine had pooling at the...
Pediatric dentistry
The effect of sealants on S. mutans presence in situ was investigated. Four intact, fully erupted... more The effect of sealants on S. mutans presence in situ was investigated. Four intact, fully erupted first permanent molars in each of 74 children, aged 6-8 years were required for inclusion in the study. Baseline examination included deft and plaque index. S. mutans presence on occlusal surfaces of the molars was evaluated, using a microbial replica method. Immediately after sealing the first permanent molars on one side, S. mutans presence in situ was re-evaluated, as well as three and six months thereafter. Three months after the initiation of the study, S. mutans presence was evaluated on the molars of the unsealed side, which were consequently sealed and re-evaluated immediately, and three months later. Positive correlation was found between deft scores, plaque indices and microbial replica values, at baseline. Sealing caused a significant reduction in S. mutans levels on the treated occlusal surfaces, in vivo (P < 0.001), which lasted, in most cases, up to six months. The data...
ASDC journal of dentistry for children
The purpose of this study was to test the ability of an electronic apex locator, Root ZX to measu... more The purpose of this study was to test the ability of an electronic apex locator, Root ZX to measure the root canal length in primary teeth with partial resorption. Twenty extracted primary molars were embedded in an alginate model imitating in vivo conditions. Root ZX and radiographic measurements were compared in dry and wet environments to the actual tooth length. Root ZX identified the tooth length at the most coronal portion of the resorption. The content of the root canal did not influence the results. No statistical differences were found between electronic, radiographic and actual tooth length measurements, although the radiographic measurements were longer than the electronic ones. It is suggested that Root ZX is a preferable auxiliary device to measure root canal length in the primary dentition.
Pediatric dentistry
Immature; M 1 --Maxillary first molar; M 2 --Maxillary second molar; M1 --Mandibular first molar;... more Immature; M 1 --Maxillary first molar; M 2 --Maxillary second molar; M1 --Mandibular first molar; M 2 --Mandibular second molar.
Oral surgery, oral medicine, and oral pathology, 1973
Oral surgery, oral medicine, and oral pathology, 1992
Familial dysautonomia is an inherited autosomal recessive disease found almost exclusively in Ash... more Familial dysautonomia is an inherited autosomal recessive disease found almost exclusively in Ashkenazi Jews. It is characterized by selective damage to the sensory, motor, and autonomic peripheral nervous system. The main clinical features include decreased pain sensation, impaired temperature and blood pressure regulation, lack of tearing, absent tendon reflexes, and fungiform papillae on the tongue. The purpose of this study was to explore in depth and to verify the oral and dental status in familial dysautonomia. Twenty-two patients and 44 match-paired healthy persons of Ashkenazi descent were examined. Patients and parents had only little concern for their oral condition. Caries prevalence was lower than normal and plaque accumulation increased in all patients. Dental trauma was found in 59% of the patients, and 32% showed orodental self-mutilation. Dental age was within normal range, and dental arch measurements implied proportionally small jaws and little crowding. The low ca...
International Journal of Paediatric Dentistry, 1994
The spread of local anaesthetic solution administered with a pressure syringe has not been studie... more The spread of local anaesthetic solution administered with a pressure syringe has not been studied as extensively in young animals having primary or mixed dentitions as in adult animals. The purpose of this investigation was to study the distribution of local anaesthetic solution injected into the periodontal ligament of young dogs. India ink was added to carpules containing 2% lidocaine and 1:100,000 epinephrine, and the spread of solution was examined macroscopically and microscopically. Injections were made with a pressure syringe (Ligmaject) at 58 sites mesial and distal to primary teeth in five dogs aged 3-9 months. Three dogs were killed within 12 hours, the other two after 5 days. Spread of the ink was studied in non-decalcified slabs, in three-dimensional cleared specimens, and in histological sections. The solution usually reached the alveolar bone crest, seeped under the periosteum and alongside vascular channels into bone marrow, reaching natural cavities such as the crypts of tooth buds and the mandibular canal. The ink did not penetrate into the enamel organ or contact the permanent tooth buds. The solution appeared to spread along the path of least resistance, governed by the intricacies of anatomical structures and fascial planes. Therefore the risk of mechanical damage to permanent tooth germs appears to be minimal.
Special Care in Dentistry, 1994
Oro-dental abnormalities are quite frequent in familial dysautonomia. The practitioner should be ... more Oro-dental abnormalities are quite frequent in familial dysautonomia. The practitioner should be familiar with this disorder, which represents a "human model" for chronic progressive oro-dental denervation. Self-injurious behavior is caused mainly by profound sensory loss. An appropriate preventive and therapeutic approach that was developed in our clinic and adapted for the special hazards of dentistry in youngsters with systemic autonomic dysfunction may improve the life quality of this particular population.
Special Care in Dentistry, 2012
Pediatric Research, 2010
ABSTRACT Down Syndrome (DS) (Trisomy 21) is a relatively common anomaly occurring in one in every... more ABSTRACT Down Syndrome (DS) (Trisomy 21) is a relatively common anomaly occurring in one in every 600-700 live births and characterized by impaired growth and development and early senescence. Signs of abnormal development have been observed on ultrasound as early as the first trimester. By the second trimester additional signs are evident on ultrasound, affecting skeletal growth as well as other organ systems. Dental anomalies include reduced tooth size and number, thin enamel and abnormal crown form as well as taurodont roots and a high frequency of missing teeth. The severity of the dental defects varies along the tooth row with later developing teeth most severely affected. Recent studies carried out on exfoliated (shed) deciduous teeth using a combination of serial microCT scans and SEM have enabled us to reconstruct the chronology and extent of intrauterine and infant growth insults in DS infants, expressed in growth and differentiation of the developing teeth. Our results for the deciduous teeth show that in DS, there is accelerated dental development in the first trimester followed by progressive growth retardation associated with impaired differentiation of the dental tissues. These changes appear to primarily affect cells derived from ectoderm affecting cell division and differentiation resulting in a smaller modified tooth germ and impaired enamel matrix formation and bio-mineralization. The resulting enamel is thin and hypomineralized and this may contribute to the severe abrasion seen in the teeth of DS children despite the associated lack of muscle tone.
Journal of Oral Pathology and Medicine, 1995
A clinical and histopathological study of radicular cysts associated with primary molars A: A cli... more A clinical and histopathological study of radicular cysts associated with primary molars A: A clitiical and histopathological study of radicular cysts associated with primary trtolars. J Oral Pathol Med 1995; 24: 458-61. © Munksgaard, 1995.
Journal of Oral Pathology and Medicine, 1994
European Archives of Paediatric Dentistry, 2007
To examine whether a talon incisor has an abnormal shape due to excess of dental hard tissues or ... more To examine whether a talon incisor has an abnormal shape due to excess of dental hard tissues or pulp. Two bilateral primary maxillary central incisors with talon cusp and a supernumerary mesiodens were removed from a 6-year-old boy. Histologically, 7 undecalcified cross sections (70 microm) were harvested from each talon tooth and from two regular primary central incisors of another child. Microradiographs of the sections were prepared and examined for enamel width, dentin width, pulp tissue area, and crown size (mesio-distal, labio-palatal) using Image Analysis. No association to other developmental disorders was observed. The mean width of the enamel and dentin was similar in the talon and the regular incisors (difference 7.5% and 2.4%, respectively). The pulp area was greater in the talon teeth (37.4%). The latter had an effect on the increase in the mesio-distal and labio-palatal dimensions of the talon teeth (17.6% and 23.9%, respectively). The fact that the talon cusp has normal enamel and dentin layers with a substantial enlarged pulp tissue suggests that similar developmental anomalies occur during tooth morphodifferentiation as in taurodontism and dens evagintus of premolars.
Developmental Medicine & Child Neurology, 2008
I dy saut onsmia Familial dysautonomia (FD) is one of the classic &'eases characterized by taste ... more I dy saut onsmia Familial dysautonomia (FD) is one of the classic &'eases characterized by taste and smell abnormalities. However, these typical features am based on data obtained h m two separate crude studies published in 1964. In the present study psychophpsicakogiitive and reflex-like hcial-behavioral responses to taste andsmell, inninepatientswitbFDand 15 healthy controls. were recorded. Five taste stimulants were presented to both studs groups, while a selection of common household odors was used for FD patients only. The patients with FD showed a markedly higher incidence of recognition failures for salty, bitter, sweet, and water stimuli than the
Quintessence international, 2005
To investigate the prevalence and severity of a labial-cervical-vertical groove (LCVG) in maxilla... more To investigate the prevalence and severity of a labial-cervical-vertical groove (LCVG) in maxillary permanent incisors and its effect on the associated gingival tissue. A total of 600 adolescents (293 boys and 307 girls, mean age 13.6+/-1.99 years) were randomly selected and examined for the presence of LCVG. The deformity was classified as mild, moderate, or severe according to predetermined criteria. Gingival coverage at the groove site was defined as normal, partial, and irregular. LCVG was found in 27 adolescents (4.5%). It was unilateral in 24 (89%) and bilateral in 3 (11%). The ratio of central to lateral incisors was 29:1. No sexual dimorphism or side prevalence were found. Mild LCVG was found in 22 incisors, moderate LCVG in 7 incisors, and severe LCVG in one incisor. Moderate LCVG was 5 to 6 times more susceptible to partial or irregular coverage of the gingival margin than mild LCVG. The gingival sulcus in teeth with LCVG demonstrated a significant (P = .001) increase in depth compared to non-LCVG teeth (1.55+/-0.90 mm vs 1.18+/-0.75 mm). An LCVG is a deformity confined predominantly to a single permanent maxillary central incisor. Its prevalence is not connected with gender. Most LCVGs are mild and often difficult to detect. However, the greater the severity, the more gingival irregularity is associated. This and the increase in sulcus depth in LCVG incisors are adverse predispositions for periodontal sequelae, calling for cautious oral hygiene maintenance.
Refuʾat ha-peh ṿeha-shinayim (Tel Aviv, Israel : 1969), 1978
Talon cusp is a rare dental anomaly hitherto considered to affect permanent dentition only. A cas... more Talon cusp is a rare dental anomaly hitherto considered to affect permanent dentition only. A case of talon cusp in a deciduous maxillary incisor is described, suggesting that both dentitions may be affected by this anomaly.
Quintessence international (Berlin, Germany : 1985)
Radiographic appearance of pulp reactions to partial pulpotomy in young permanent molars with dee... more Radiographic appearance of pulp reactions to partial pulpotomy in young permanent molars with deep caries may determine the efficiency of the procedure. The objective of this study was to determine the value of this procedure by analyzing the pulpal and periapical appearance of permanent molars after long-term follow-up periods. Based on predetermined radiologic criteria, periapical radiographs of 49 young permanent molars of 31 females and 13 males, aged 6.9 to 17.7 years (mean, 11.4 years) treated with partial pulpotomy were evaluated and compared to their antimeres. Follow-up time ranged from 7 to 154 months (mean, 49 months). Based on clinical and radiographic findings, the success rate was considered 93.9% (46 of 49 teeth). Three teeth had chronic pulpitis with periapical exacerbation. In 14 (30.4%) of the 46 teeth, normal radiographic pulp appearance was found, and in 2 (4.3%), pulpal calcifications were similar to their antimere tooth. Dentinal bridges were observed underneat...
European Journal of Paediatric Dentistry
This was to evaluate some suggested diagnostic procedures, treatment policies and professional at... more This was to evaluate some suggested diagnostic procedures, treatment policies and professional attitudes of specialists in paediatric dentistry, in light of the periodically published guidelines by The American Academy of Pediatric Dentistry, The European Academy of Paediatric Dentistry and The British Society of Paediatric Dentistry. Using a structured questionnaire, 67% of the Israeli specialists in paediatric dentistry, who agreed to participate in this study, were personally interviewed. Only 7.5% of the participants reported that they carry out pulp capping of primary teeth in cases of pulp exposure. Over 50% reported restoring teeth after pulpotomy with preformed crowns. Most indicated sealing pit and fissures after considering depth and morphology of the fissures and correlation with the patient's risk to caries. Cleaning teeth after eruption of the first tooth was suggested by 75.5% of the participants. A striking majority (96%) claimed that they restored permanent anter...
Pediatric dentistry
Extremely low caries rate and increased major salivary gland flow rare have been previously repor... more Extremely low caries rate and increased major salivary gland flow rare have been previously reported in children with familial dysautonomia (FD). The purpose of this study was to explore the possibility that, in addition to increased salivary flow, children with FD have alterations in their salivary components, which may suggest an explanauon to their low caries rate. Whole unstimulated and stimulated saliva samples were collected from 13 children with FD who were found to be caries free, and from 28 age- and ethnic-matched healthy children, 15 caries-free children and 13 caries-affected children. The electrolyte and protein content of the unstimulated saliva and the microbial count and buffering capacity of the stimulated saliva were determined. Children with FD had the highest salivary flow rate and the lowest levels of mutans streptococci and lactobacilli, as well as the lowest concentration of chloride, magnesium, total protein and IgA. Healthy caries-affected children displayed...
ASDC journal of dentistry for children
The aim of the present retrospective study was to observe the clinical and radiographic performan... more The aim of the present retrospective study was to observe the clinical and radiographic performances of a compomer (Dyract) in proximal restorations of primary molars as compared to amalgam restorations. The study was performed at the principal investigator's office. Children between three to eleven years old, who had at least two primary molars with a small to moderate approximal caries lesion were included in the study. The assessed material consisted of 107 proximal restorations (63 Dyract and 44 amalgam) placed in primary molars during the years 1994 to 1997 in forty-two children who were available for follow-up examinations. All the evaluated restorations were clinically acceptable, with smooth surface appearance, satisfactory color match, neither secondary caries nor fracture. The margins of two Dyract restorations presented minimal stain. Of the 63 Dyract restorations evaluated radiographically, two presented with bubbles, one with an overhang, and nine had pooling at the...
Pediatric dentistry
The effect of sealants on S. mutans presence in situ was investigated. Four intact, fully erupted... more The effect of sealants on S. mutans presence in situ was investigated. Four intact, fully erupted first permanent molars in each of 74 children, aged 6-8 years were required for inclusion in the study. Baseline examination included deft and plaque index. S. mutans presence on occlusal surfaces of the molars was evaluated, using a microbial replica method. Immediately after sealing the first permanent molars on one side, S. mutans presence in situ was re-evaluated, as well as three and six months thereafter. Three months after the initiation of the study, S. mutans presence was evaluated on the molars of the unsealed side, which were consequently sealed and re-evaluated immediately, and three months later. Positive correlation was found between deft scores, plaque indices and microbial replica values, at baseline. Sealing caused a significant reduction in S. mutans levels on the treated occlusal surfaces, in vivo (P < 0.001), which lasted, in most cases, up to six months. The data...
ASDC journal of dentistry for children
The purpose of this study was to test the ability of an electronic apex locator, Root ZX to measu... more The purpose of this study was to test the ability of an electronic apex locator, Root ZX to measure the root canal length in primary teeth with partial resorption. Twenty extracted primary molars were embedded in an alginate model imitating in vivo conditions. Root ZX and radiographic measurements were compared in dry and wet environments to the actual tooth length. Root ZX identified the tooth length at the most coronal portion of the resorption. The content of the root canal did not influence the results. No statistical differences were found between electronic, radiographic and actual tooth length measurements, although the radiographic measurements were longer than the electronic ones. It is suggested that Root ZX is a preferable auxiliary device to measure root canal length in the primary dentition.
Pediatric dentistry
Immature; M 1 --Maxillary first molar; M 2 --Maxillary second molar; M1 --Mandibular first molar;... more Immature; M 1 --Maxillary first molar; M 2 --Maxillary second molar; M1 --Mandibular first molar; M 2 --Mandibular second molar.
Oral surgery, oral medicine, and oral pathology, 1973
Oral surgery, oral medicine, and oral pathology, 1992
Familial dysautonomia is an inherited autosomal recessive disease found almost exclusively in Ash... more Familial dysautonomia is an inherited autosomal recessive disease found almost exclusively in Ashkenazi Jews. It is characterized by selective damage to the sensory, motor, and autonomic peripheral nervous system. The main clinical features include decreased pain sensation, impaired temperature and blood pressure regulation, lack of tearing, absent tendon reflexes, and fungiform papillae on the tongue. The purpose of this study was to explore in depth and to verify the oral and dental status in familial dysautonomia. Twenty-two patients and 44 match-paired healthy persons of Ashkenazi descent were examined. Patients and parents had only little concern for their oral condition. Caries prevalence was lower than normal and plaque accumulation increased in all patients. Dental trauma was found in 59% of the patients, and 32% showed orodental self-mutilation. Dental age was within normal range, and dental arch measurements implied proportionally small jaws and little crowding. The low ca...
International Journal of Paediatric Dentistry, 1994
The spread of local anaesthetic solution administered with a pressure syringe has not been studie... more The spread of local anaesthetic solution administered with a pressure syringe has not been studied as extensively in young animals having primary or mixed dentitions as in adult animals. The purpose of this investigation was to study the distribution of local anaesthetic solution injected into the periodontal ligament of young dogs. India ink was added to carpules containing 2% lidocaine and 1:100,000 epinephrine, and the spread of solution was examined macroscopically and microscopically. Injections were made with a pressure syringe (Ligmaject) at 58 sites mesial and distal to primary teeth in five dogs aged 3-9 months. Three dogs were killed within 12 hours, the other two after 5 days. Spread of the ink was studied in non-decalcified slabs, in three-dimensional cleared specimens, and in histological sections. The solution usually reached the alveolar bone crest, seeped under the periosteum and alongside vascular channels into bone marrow, reaching natural cavities such as the crypts of tooth buds and the mandibular canal. The ink did not penetrate into the enamel organ or contact the permanent tooth buds. The solution appeared to spread along the path of least resistance, governed by the intricacies of anatomical structures and fascial planes. Therefore the risk of mechanical damage to permanent tooth germs appears to be minimal.
Special Care in Dentistry, 1994
Oro-dental abnormalities are quite frequent in familial dysautonomia. The practitioner should be ... more Oro-dental abnormalities are quite frequent in familial dysautonomia. The practitioner should be familiar with this disorder, which represents a "human model" for chronic progressive oro-dental denervation. Self-injurious behavior is caused mainly by profound sensory loss. An appropriate preventive and therapeutic approach that was developed in our clinic and adapted for the special hazards of dentistry in youngsters with systemic autonomic dysfunction may improve the life quality of this particular population.
Special Care in Dentistry, 2012
Pediatric Research, 2010
ABSTRACT Down Syndrome (DS) (Trisomy 21) is a relatively common anomaly occurring in one in every... more ABSTRACT Down Syndrome (DS) (Trisomy 21) is a relatively common anomaly occurring in one in every 600-700 live births and characterized by impaired growth and development and early senescence. Signs of abnormal development have been observed on ultrasound as early as the first trimester. By the second trimester additional signs are evident on ultrasound, affecting skeletal growth as well as other organ systems. Dental anomalies include reduced tooth size and number, thin enamel and abnormal crown form as well as taurodont roots and a high frequency of missing teeth. The severity of the dental defects varies along the tooth row with later developing teeth most severely affected. Recent studies carried out on exfoliated (shed) deciduous teeth using a combination of serial microCT scans and SEM have enabled us to reconstruct the chronology and extent of intrauterine and infant growth insults in DS infants, expressed in growth and differentiation of the developing teeth. Our results for the deciduous teeth show that in DS, there is accelerated dental development in the first trimester followed by progressive growth retardation associated with impaired differentiation of the dental tissues. These changes appear to primarily affect cells derived from ectoderm affecting cell division and differentiation resulting in a smaller modified tooth germ and impaired enamel matrix formation and bio-mineralization. The resulting enamel is thin and hypomineralized and this may contribute to the severe abrasion seen in the teeth of DS children despite the associated lack of muscle tone.
Journal of Oral Pathology and Medicine, 1995
A clinical and histopathological study of radicular cysts associated with primary molars A: A cli... more A clinical and histopathological study of radicular cysts associated with primary molars A: A clitiical and histopathological study of radicular cysts associated with primary trtolars. J Oral Pathol Med 1995; 24: 458-61. © Munksgaard, 1995.
Journal of Oral Pathology and Medicine, 1994
European Archives of Paediatric Dentistry, 2007
To examine whether a talon incisor has an abnormal shape due to excess of dental hard tissues or ... more To examine whether a talon incisor has an abnormal shape due to excess of dental hard tissues or pulp. Two bilateral primary maxillary central incisors with talon cusp and a supernumerary mesiodens were removed from a 6-year-old boy. Histologically, 7 undecalcified cross sections (70 microm) were harvested from each talon tooth and from two regular primary central incisors of another child. Microradiographs of the sections were prepared and examined for enamel width, dentin width, pulp tissue area, and crown size (mesio-distal, labio-palatal) using Image Analysis. No association to other developmental disorders was observed. The mean width of the enamel and dentin was similar in the talon and the regular incisors (difference 7.5% and 2.4%, respectively). The pulp area was greater in the talon teeth (37.4%). The latter had an effect on the increase in the mesio-distal and labio-palatal dimensions of the talon teeth (17.6% and 23.9%, respectively). The fact that the talon cusp has normal enamel and dentin layers with a substantial enlarged pulp tissue suggests that similar developmental anomalies occur during tooth morphodifferentiation as in taurodontism and dens evagintus of premolars.
Developmental Medicine & Child Neurology, 2008
I dy saut onsmia Familial dysautonomia (FD) is one of the classic &'eases characterized by taste ... more I dy saut onsmia Familial dysautonomia (FD) is one of the classic &'eases characterized by taste and smell abnormalities. However, these typical features am based on data obtained h m two separate crude studies published in 1964. In the present study psychophpsicakogiitive and reflex-like hcial-behavioral responses to taste andsmell, inninepatientswitbFDand 15 healthy controls. were recorded. Five taste stimulants were presented to both studs groups, while a selection of common household odors was used for FD patients only. The patients with FD showed a markedly higher incidence of recognition failures for salty, bitter, sweet, and water stimuli than the