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Research paper thumbnail of Fabrication of duplex-layer coating on metallic implants: Advanced surface modification of metallic implants for orthopedic applications

Research paper thumbnail of Naturally derived ceramics–polymer composite for biomedical applications

Research paper thumbnail of Leucas aspera assisted green synthesis of mineralized hydroxyapatite/polycaprolactone: A potential composite for biomedical applications

Research paper thumbnail of Biocomposite coating of Wrightia tinctoria root bark fiber reinforced samarium substituted hydroxyapatite/ polypyrrole on titanium for potential orthopedic applications

Materials Chemistry and Physics

Research paper thumbnail of A Multifunctional Carbon Nanofiber/Bioceramic Coating for Orthopedic Applications

Carbon nanofibers (CNF), one of the most significant nanomaterials with unique mechanical, biolog... more Carbon nanofibers (CNF), one of the most significant nanomaterials with unique mechanical, biological and surface properties, has been shown as suitable for various biomedical applications. In the present work we report the development of CNF reinforced mineral (manganese) substituted hydroxyapatite (Mn-HAP) composite on titanium alloy (Ti6Al4V). Hydroxyapatite (HAP, [Ca10(PO4)6(OH)2]) is a widely used biomaterial for bone implant applications due to its osteoconductive and bioactive properties. Application of HAP in orthopedic implants suffers from its low fracture toughness and poor wear resistance. To surmount these issues, CNF is used as an excellent reinforcement material for imparting strength and toughness to brittle HAP. The phase composition and surface microstructure of the obtained coating were evaluated by FT-IR, XRD and SEM-EDX, respectively. The effect of reinforcement of CNF and the substitution of Mn in HAP on the mechanical and biological properties of the CNF/M-HAP...

Research paper thumbnail of A preliminary study on the synthesis of biogenic derived hydroxyapatite /medicinal plant extracts composite for potential bone tissue engineering applications

Materials Today: Proceedings, 2022

Research paper thumbnail of Multifunctional crab shell derived hydroxyapatite/metal oxide/polyhydroxybutyrate composite coating on 316L SS for biomedical applications

Research paper thumbnail of Biogenic synthesis of hydroxyapatite/Musa paradisiaca floral sap for biomedical applications

Research paper thumbnail of Electrodeposition of manganese substituted hydroxyapatite/zinc oxide duplex-layer on AZ91 magnesium alloy for orthopaedic applications

AZ91 Magnesium alloy (AZ91 Mg alloy) has been developed as a biodegradable implant material becau... more AZ91 Magnesium alloy (AZ91 Mg alloy) has been developed as a biodegradable implant material because of its outstanding biodegradability and mechanical properties. But the poor corrosion resistance of AZ91 Mg alloy in physiological solution limits its biomedical applications. In order to improve the corrosion resistance and biological performance of AZ91 Mg alloy, we have fabricated a manganese-subs tituted porous hydroxyapatite (Mn- HAP)/zinc oxide (ZnO) duplex layer on AZ91 Mg alloy by electrodeposi tion. The porous Mn-HAP/ZnO duplex-layer coating on AZ91 Mg alloy was characterized by Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), field emission scanning electron microscopy and energy dispersive X-ray analysis (FESEM-EDAX). Also, the mechanical properties of the duplex-layer coatings were evaluated using adhesion and Vickers micro-hardness tests. The effects of the duplex-layer coating on the corrosion behavior of AZ91 Mg alloy were also investigated in si...

Research paper thumbnail of Development of carbon nanotubes reinforced bioceramic composite coatings on titanium for orthopedic applications

Research paper thumbnail of Structural, morphological and biological evaluations of cerium incorporated hydroxyapatite sol–gel coatings on Ti–6Al–4V for orthopaedic applications

Journal of Materials Research and Technology, 2021

Research paper thumbnail of Biowaste‐derived hydroxyapatite reinforced with polyvinyl pyrrolidone/aloevera composite for biomedical applications

International Journal of Applied Ceramic Technology, 2020

The present investigation focuses on the synthesis of crabshell‐derived hydroxyapatite (CS‐HAP)/ ... more The present investigation focuses on the synthesis of crabshell‐derived hydroxyapatite (CS‐HAP)/ water‐soluble synthetic polymer—polyvinylpyrrolidone(PVP)/aloevera(AV)—a natural biopolymer, as a composite for enhanced mechanical, antibacterial and biocompatible properties. The reinforcement of polymer has a significant function in increasing the mechanical property of the composite, whereas the incorporation of AV improves the antibacterial and biocompatibility. Phase composition, morphology, mechanical property, and hydrophilicity of CS‐HAP/PVP/AV biocomposite with different concentrations of PVP and AV were examined by Fourier transform infrared spectroscopy (FTIR), X‐Ray diffraction (XRD), scanning electron microscopy with energy dispersive X‐ray (SEM‐EDX), Vickers microhardness tests, contact angle, respectively. Furthermore, the antibacterial efficiency of the composite is assessed using Escherichia coli (E coli) and Staphylococcus aureus (S aureus). The biocompatibility of HOS...

Research paper thumbnail of Correction to “Carbon Nanotubes/Carboxymethyl Chitosan/Mineralized Hydroxyapatite Composite Coating on Ti-6Al-4V Alloy for Improved Mechanical and Biological Properties”

Industrial & Engineering Chemistry Research, 2019

Research paper thumbnail of A comparative study of naturally and synthetically derived bioceramics for biomedical applications

Materials Today: Proceedings, 2019

Research paper thumbnail of Tailoring the Sm/Gd-Substituted Hydroxyapatite Coating on Biomedical AISI 316L SS: Exploration of Corrosion Resistance, Protein Profiling, Osteocompatibility, and Osteogenic Differentiation for Orthopedic Implant Applications

Industrial & Engineering Chemistry Research, 2016

Research paper thumbnail of Carbon Nanotubes-reinforced Bioceramic Composite: An Advanced Coating Material for Orthopedic Applications

Advanced Composite Materials, 2016

Research paper thumbnail of Influence of ionic substitution in improving the biological property of carbon nanotubes reinforced hydroxyapatite composite coating on titanium for orthopedic applications

Ceramics International, 2015

Research paper thumbnail of Synthesis and spectral characterization of silver/magnesium co-substituted hydroxyapatite for biomedical applications

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, Jan 5, 2014

The present work is aimed at the synthesis of antibacterial and bioactive silver/magnesium co-sub... more The present work is aimed at the synthesis of antibacterial and bioactive silver/magnesium co-substituted hydroxyapatite (Ag/Mg-HAP) powders. For this purpose, firstly, different concentrations (0.5, 1.5, 2.5wt.%) of silver substituted HAP (Ag-HAP) powders were prepared by ultrasonic irradiation technique and were characterized by Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), scanning electron microscopy (SEM) and energy dispersive X-ray analysis (EDAX). Secondly, magnesium (Mg) is co-substituted as secondary material into Ag-HAP to offset the potential cytotoxicity of Ag, as higher concentration of Ag is toxic. The antibacterial activity of as-synthesized powders was evaluated by Escherichia coli (E. coli) and was found to be effectively high against bacterial colonization. Also, the in vitro cell-material interaction is evaluated with human osteosarcoma MG63 (HOS MG63) cells for cell proliferation. The results showed the evidence of cytotoxic effects of ...

Research paper thumbnail of Spectroscopic investigation on formation and growth of mineralized nanohydroxyapatite for bone tissue engineering applications

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2012

Research paper thumbnail of Carbon Nanotubes/Carboxymethyl Chitosan/Mineralized Hydroxyapatite Composite Coating on Ti-6Al-4V Alloy for Improved Mechanical and Biological Properties

Industrial & Engineering Chemistry Research, 2014

Research paper thumbnail of Fabrication of duplex-layer coating on metallic implants: Advanced surface modification of metallic implants for orthopedic applications

Research paper thumbnail of Naturally derived ceramics–polymer composite for biomedical applications

Research paper thumbnail of Leucas aspera assisted green synthesis of mineralized hydroxyapatite/polycaprolactone: A potential composite for biomedical applications

Research paper thumbnail of Biocomposite coating of Wrightia tinctoria root bark fiber reinforced samarium substituted hydroxyapatite/ polypyrrole on titanium for potential orthopedic applications

Materials Chemistry and Physics

Research paper thumbnail of A Multifunctional Carbon Nanofiber/Bioceramic Coating for Orthopedic Applications

Carbon nanofibers (CNF), one of the most significant nanomaterials with unique mechanical, biolog... more Carbon nanofibers (CNF), one of the most significant nanomaterials with unique mechanical, biological and surface properties, has been shown as suitable for various biomedical applications. In the present work we report the development of CNF reinforced mineral (manganese) substituted hydroxyapatite (Mn-HAP) composite on titanium alloy (Ti6Al4V). Hydroxyapatite (HAP, [Ca10(PO4)6(OH)2]) is a widely used biomaterial for bone implant applications due to its osteoconductive and bioactive properties. Application of HAP in orthopedic implants suffers from its low fracture toughness and poor wear resistance. To surmount these issues, CNF is used as an excellent reinforcement material for imparting strength and toughness to brittle HAP. The phase composition and surface microstructure of the obtained coating were evaluated by FT-IR, XRD and SEM-EDX, respectively. The effect of reinforcement of CNF and the substitution of Mn in HAP on the mechanical and biological properties of the CNF/M-HAP...

Research paper thumbnail of A preliminary study on the synthesis of biogenic derived hydroxyapatite /medicinal plant extracts composite for potential bone tissue engineering applications

Materials Today: Proceedings, 2022

Research paper thumbnail of Multifunctional crab shell derived hydroxyapatite/metal oxide/polyhydroxybutyrate composite coating on 316L SS for biomedical applications

Research paper thumbnail of Biogenic synthesis of hydroxyapatite/Musa paradisiaca floral sap for biomedical applications

Research paper thumbnail of Electrodeposition of manganese substituted hydroxyapatite/zinc oxide duplex-layer on AZ91 magnesium alloy for orthopaedic applications

AZ91 Magnesium alloy (AZ91 Mg alloy) has been developed as a biodegradable implant material becau... more AZ91 Magnesium alloy (AZ91 Mg alloy) has been developed as a biodegradable implant material because of its outstanding biodegradability and mechanical properties. But the poor corrosion resistance of AZ91 Mg alloy in physiological solution limits its biomedical applications. In order to improve the corrosion resistance and biological performance of AZ91 Mg alloy, we have fabricated a manganese-subs tituted porous hydroxyapatite (Mn- HAP)/zinc oxide (ZnO) duplex layer on AZ91 Mg alloy by electrodeposi tion. The porous Mn-HAP/ZnO duplex-layer coating on AZ91 Mg alloy was characterized by Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), field emission scanning electron microscopy and energy dispersive X-ray analysis (FESEM-EDAX). Also, the mechanical properties of the duplex-layer coatings were evaluated using adhesion and Vickers micro-hardness tests. The effects of the duplex-layer coating on the corrosion behavior of AZ91 Mg alloy were also investigated in si...

Research paper thumbnail of Development of carbon nanotubes reinforced bioceramic composite coatings on titanium for orthopedic applications

Research paper thumbnail of Structural, morphological and biological evaluations of cerium incorporated hydroxyapatite sol–gel coatings on Ti–6Al–4V for orthopaedic applications

Journal of Materials Research and Technology, 2021

Research paper thumbnail of Biowaste‐derived hydroxyapatite reinforced with polyvinyl pyrrolidone/aloevera composite for biomedical applications

International Journal of Applied Ceramic Technology, 2020

The present investigation focuses on the synthesis of crabshell‐derived hydroxyapatite (CS‐HAP)/ ... more The present investigation focuses on the synthesis of crabshell‐derived hydroxyapatite (CS‐HAP)/ water‐soluble synthetic polymer—polyvinylpyrrolidone(PVP)/aloevera(AV)—a natural biopolymer, as a composite for enhanced mechanical, antibacterial and biocompatible properties. The reinforcement of polymer has a significant function in increasing the mechanical property of the composite, whereas the incorporation of AV improves the antibacterial and biocompatibility. Phase composition, morphology, mechanical property, and hydrophilicity of CS‐HAP/PVP/AV biocomposite with different concentrations of PVP and AV were examined by Fourier transform infrared spectroscopy (FTIR), X‐Ray diffraction (XRD), scanning electron microscopy with energy dispersive X‐ray (SEM‐EDX), Vickers microhardness tests, contact angle, respectively. Furthermore, the antibacterial efficiency of the composite is assessed using Escherichia coli (E coli) and Staphylococcus aureus (S aureus). The biocompatibility of HOS...

Research paper thumbnail of Correction to “Carbon Nanotubes/Carboxymethyl Chitosan/Mineralized Hydroxyapatite Composite Coating on Ti-6Al-4V Alloy for Improved Mechanical and Biological Properties”

Industrial & Engineering Chemistry Research, 2019

Research paper thumbnail of A comparative study of naturally and synthetically derived bioceramics for biomedical applications

Materials Today: Proceedings, 2019

Research paper thumbnail of Tailoring the Sm/Gd-Substituted Hydroxyapatite Coating on Biomedical AISI 316L SS: Exploration of Corrosion Resistance, Protein Profiling, Osteocompatibility, and Osteogenic Differentiation for Orthopedic Implant Applications

Industrial & Engineering Chemistry Research, 2016

Research paper thumbnail of Carbon Nanotubes-reinforced Bioceramic Composite: An Advanced Coating Material for Orthopedic Applications

Advanced Composite Materials, 2016

Research paper thumbnail of Influence of ionic substitution in improving the biological property of carbon nanotubes reinforced hydroxyapatite composite coating on titanium for orthopedic applications

Ceramics International, 2015

Research paper thumbnail of Synthesis and spectral characterization of silver/magnesium co-substituted hydroxyapatite for biomedical applications

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, Jan 5, 2014

The present work is aimed at the synthesis of antibacterial and bioactive silver/magnesium co-sub... more The present work is aimed at the synthesis of antibacterial and bioactive silver/magnesium co-substituted hydroxyapatite (Ag/Mg-HAP) powders. For this purpose, firstly, different concentrations (0.5, 1.5, 2.5wt.%) of silver substituted HAP (Ag-HAP) powders were prepared by ultrasonic irradiation technique and were characterized by Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), scanning electron microscopy (SEM) and energy dispersive X-ray analysis (EDAX). Secondly, magnesium (Mg) is co-substituted as secondary material into Ag-HAP to offset the potential cytotoxicity of Ag, as higher concentration of Ag is toxic. The antibacterial activity of as-synthesized powders was evaluated by Escherichia coli (E. coli) and was found to be effectively high against bacterial colonization. Also, the in vitro cell-material interaction is evaluated with human osteosarcoma MG63 (HOS MG63) cells for cell proliferation. The results showed the evidence of cytotoxic effects of ...

Research paper thumbnail of Spectroscopic investigation on formation and growth of mineralized nanohydroxyapatite for bone tissue engineering applications

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2012

Research paper thumbnail of Carbon Nanotubes/Carboxymethyl Chitosan/Mineralized Hydroxyapatite Composite Coating on Ti-6Al-4V Alloy for Improved Mechanical and Biological Properties

Industrial & Engineering Chemistry Research, 2014

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