Eko Sudarmo - Academia.edu (original) (raw)
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Papers by Eko Sudarmo
F1000Research
Background: Helicobacter pylori (H. pylori) infection status in Indonesia might be higher than th... more Background: Helicobacter pylori (H. pylori) infection status in Indonesia might be higher than the actual prevalence. A comprehensive epidemiologic study is necessary to explore infection susceptibility by demographic characteristics, especially between Indonesia’s Eastern and Western regions. Methods: We included our recent survey and data from our previous studies with 1,172 endoscopic examinations from 19 cities throughout Indonesia from January 2014 to March 2017. H. pylori infection was diagnosed based on the combination of four different tests. Using a criterion of one positive result between four tests, we found that 190 subjects (190/1,158; 16.4%) were H. pylori positive. A total of 939 subjects were analyzed for risk factors of sociodemographic characteristics to H. pylori infection. Results: Prevalence was slightly higher in the Eastern region compared with the Western region of Indonesia (79/277; 59.4% vs. 54/529; 40.6%). Living in the Eastern region imposes a higher risk...
<p><i>H</i>. <i>pylori</i>-negative gastritis in Indonesia.</p
<p>(<b>A</b>) We observed the 50–59 and ≥60 year-old groups had significantly h... more <p>(<b>A</b>) We observed the 50–59 and ≥60 year-old groups had significantly higher OLGA scores than those in the 30–39 age group. As expected the individuals infected with <i>H</i>. <i>pylori</i> had significantly higher OLGA scores than non-infected individuals. (<b>B</b>) We found three ethnic groups (Timor, Papuan, and Bataknese) with significantly higher OLGA scores than people in the Kaili ethnic group (P = 0.003, P = 0.025, and 0.040, respectively).</p
<p>The overall observation of gastric mucosal condition in Indonesia.</p
<p>Topography of acute gastritis in Indonesia.</p
<p>Map of gastric cancer risk among ethnic group in Indonesia.</p
<p>Risk factor of GC precusor in Indonesia.</p
<p>The gastric cancer risk index score of Indonesian patients.</p
Journal of Research in Medical Sciences
<p>Topography of chronic gastritis in Indonesian patients.</p
PLOS ONE, 2019
Indonesia is a big country with multiethnic populations whose gastric cancer risks have not been ... more Indonesia is a big country with multiethnic populations whose gastric cancer risks have not been elucidated. We performed a nationwide survey and obtained histological specimens from 1053 individuals in 19 cities across the country. We examined the gastric mucosa, the topography, the atrophic gastritis risk factors, and the gastric cancer risk scores. Almost half (46.1%) of the patients with dyspeptic symptoms had histological abnormalities; chronic (36.3%) and atrophic gastritis (28.9%) being the most frequent. Individuals of the Timor ethnicity had the highest prevalence of acute (52.6%) and chronic gastritis (68.4%), even those negative for H. pylori. Our topographic analysis showed the majority of patients had predominantly antral acute and chronic gastritis. A multivariate logistic regression model showed age (Odds ratio [OR], 1.107), Timor ethnicity (OR, 8.531), and H. pylori infection (OR, 22.643) as independent risk factors for presence of atrophic gastritis. In addition, the gastric
F1000Research
Background: Helicobacter pylori (H. pylori) infection status in Indonesia might be higher than th... more Background: Helicobacter pylori (H. pylori) infection status in Indonesia might be higher than the actual prevalence. A comprehensive epidemiologic study is necessary to explore infection susceptibility by demographic characteristics, especially between Indonesia’s Eastern and Western regions. Methods: We included our recent survey and data from our previous studies with 1,172 endoscopic examinations from 19 cities throughout Indonesia from January 2014 to March 2017. H. pylori infection was diagnosed based on the combination of four different tests. Using a criterion of one positive result between four tests, we found that 190 subjects (190/1,158; 16.4%) were H. pylori positive. A total of 939 subjects were analyzed for risk factors of sociodemographic characteristics to H. pylori infection. Results: Prevalence was slightly higher in the Eastern region compared with the Western region of Indonesia (79/277; 59.4% vs. 54/529; 40.6%). Living in the Eastern region imposes a higher risk...
<p><i>H</i>. <i>pylori</i>-negative gastritis in Indonesia.</p
<p>(<b>A</b>) We observed the 50–59 and ≥60 year-old groups had significantly h... more <p>(<b>A</b>) We observed the 50–59 and ≥60 year-old groups had significantly higher OLGA scores than those in the 30–39 age group. As expected the individuals infected with <i>H</i>. <i>pylori</i> had significantly higher OLGA scores than non-infected individuals. (<b>B</b>) We found three ethnic groups (Timor, Papuan, and Bataknese) with significantly higher OLGA scores than people in the Kaili ethnic group (P = 0.003, P = 0.025, and 0.040, respectively).</p
<p>The overall observation of gastric mucosal condition in Indonesia.</p
<p>Topography of acute gastritis in Indonesia.</p
<p>Map of gastric cancer risk among ethnic group in Indonesia.</p
<p>Risk factor of GC precusor in Indonesia.</p
<p>The gastric cancer risk index score of Indonesian patients.</p
Journal of Research in Medical Sciences
<p>Topography of chronic gastritis in Indonesian patients.</p
PLOS ONE, 2019
Indonesia is a big country with multiethnic populations whose gastric cancer risks have not been ... more Indonesia is a big country with multiethnic populations whose gastric cancer risks have not been elucidated. We performed a nationwide survey and obtained histological specimens from 1053 individuals in 19 cities across the country. We examined the gastric mucosa, the topography, the atrophic gastritis risk factors, and the gastric cancer risk scores. Almost half (46.1%) of the patients with dyspeptic symptoms had histological abnormalities; chronic (36.3%) and atrophic gastritis (28.9%) being the most frequent. Individuals of the Timor ethnicity had the highest prevalence of acute (52.6%) and chronic gastritis (68.4%), even those negative for H. pylori. Our topographic analysis showed the majority of patients had predominantly antral acute and chronic gastritis. A multivariate logistic regression model showed age (Odds ratio [OR], 1.107), Timor ethnicity (OR, 8.531), and H. pylori infection (OR, 22.643) as independent risk factors for presence of atrophic gastritis. In addition, the gastric