E. Zurauskas - Academia.edu (original) (raw)

E. Zurauskas

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Papers by E. Zurauskas

Research paper thumbnail of 64P Comprehensive genomic analysis of primary triple negative breast cancer prior to neoadjuvant chemotherapy

Research paper thumbnail of Morphometric study of age-related changes in the human intracardiac ganglia

Medicina (Kaunas, Lithuania), 2004

The present study was performed in order to determine morphological age-related changes of the hu... more The present study was performed in order to determine morphological age-related changes of the human intracardiac ganglia. Paraffin sections of 40 ganglia from infants, adult and aged human hearts were stained with Picro-Mallory method. The ganglia area, nerve cell (with clearly visible nucleolus) area, neuron soma long axis length, perimeter, area of neuronal nuclei and neuron soma form factor were measured with the aid of computer images analyzing program "Sigma Scan Pro 5.0". Also, the neuronal density and the area occupied by nerve cells per ganglion section were calculated. The relative frequency of satellite cells, in close contact with nerve cell soma, was estimated. Based on the data of this study, we concluded that the area of ganglia, neurons and their nuclei increased with age. Neuronal packing density significantly decreased, but the area occupied by nerve cells within the ganglia decreased non-significantly. Satellite cells were more numerous nearby ganglion n...

Research paper thumbnail of Spectroscopic studies of the human heart conduction system ex vivo: Implication for optical visualization

Journal of Photochemistry and Photobiology B: Biology, 2008

Research paper thumbnail of Spectroscopic studies of the human heart conduction system ex vivo: Implication for optical visualization

Journal of Photochemistry and Photobiology B: Biology, 2008

Research paper thumbnail of Imaging of histological sections of the human intestine by multimodal CARS microscope

Lithuanian Journal of Physics, 2012

Research paper thumbnail of Quantification of myocardial fibrosis by digital image analysis and interactive stereology

Background: Cardiac fibrosis disrupts the normal myocardial structure and has a direct impact on ... more Background: Cardiac fibrosis disrupts the normal myocardial structure and has a direct impact on heart function and survival. Despite already available digital methods, the pathologist's visual score is still widely considered as ground truth and used as a primary method in histomorphometric evaluations. The aim of this study was to compare the accuracy of digital image analysis tools and the pathologist's visual scoring for evaluating fibrosis in human myocardial biopsies, based on reference data obtained by point counting performed on the same images.

Research paper thumbnail of Proton Motor unveils new-generation 30 kW PM400 fuel cell stack

Research paper thumbnail of Editorial Board

Research paper thumbnail of Quantification of myocardial fibrosis by digital image analysis and interactive stereology

Background: Cardiac fibrosis disrupts the normal myocardial structure and has a direct impact on ... more Background: Cardiac fibrosis disrupts the normal myocardial structure and has a direct impact on heart function and survival. Despite already available digital methods, the pathologist's visual score is still widely considered as ground truth and used as a primary method in histomorphometric evaluations. The aim of this study was to compare the accuracy of digital image analysis tools and the pathologist's visual scoring for evaluating fibrosis in human myocardial biopsies, based on reference data obtained by point counting performed on the same images.

Research paper thumbnail of Index

Research paper thumbnail of Non-Ischemic Dilated Cardiomyopathy: Biopsy Proved Markers of Disease Sub-Entities

The Journal of Heart and Lung Transplantation, 2014

Research paper thumbnail of Proton Motor unveils new-generation 30 kW PM400 fuel cell stack

Research paper thumbnail of Editorial Board

Research paper thumbnail of Quantification of myocardial fibrosis by digital image analysis and interactive stereology

Background: Cardiac fibrosis disrupts the normal myocardial structure and has a direct impact on ... more Background: Cardiac fibrosis disrupts the normal myocardial structure and has a direct impact on heart function and survival. Despite already available digital methods, the pathologist's visual score is still widely considered as ground truth and used as a primary method in histomorphometric evaluations. The aim of this study was to compare the accuracy of digital image analysis tools and the pathologist's visual scoring for evaluating fibrosis in human myocardial biopsies, based on reference data obtained by point counting performed on the same images.

Research paper thumbnail of Spectroscopic studies of the human heart conduction system ex vivo: Implication for optical visualization

Journal of Photochemistry and Photobiology B: Biology, 2008

Fluorescence excitation and emission spectra of the heart tissues specimens have been measured ex... more Fluorescence excitation and emission spectra of the heart tissues specimens have been measured ex vivo with the aim of finding out the optical differences characteristic for the human heart conduction system (the His bundle) and ventricular myocardium.

Research paper thumbnail of M.539 Detection of Chlamydia pneumoniae in atherosclerothic tissue and investigation of serological status in patients with chronic atherosclerosis

Atherosclerosis, 2004

Objectives: Inflammatory factors together with classical risk factors ale important in the develo... more Objectives: Inflammatory factors together with classical risk factors ale important in the development of atherosclerosis. Chronic inflammation developed in at'terial wall could be like a response promoted by microol~ ganisms. Many infectious agents are investigated in order to establish thehethiopathogenetical role in the process of atherosclerosis but Chlamydia pneumoniae has the strongest implication. The potential role of this agent is being investigated in seroepidemiological, experimental, atherosclerothic tissue studies and clinical trials with antibiotics.

Research paper thumbnail of 64P Comprehensive genomic analysis of primary triple negative breast cancer prior to neoadjuvant chemotherapy

Research paper thumbnail of Morphometric study of age-related changes in the human intracardiac ganglia

Medicina (Kaunas, Lithuania), 2004

The present study was performed in order to determine morphological age-related changes of the hu... more The present study was performed in order to determine morphological age-related changes of the human intracardiac ganglia. Paraffin sections of 40 ganglia from infants, adult and aged human hearts were stained with Picro-Mallory method. The ganglia area, nerve cell (with clearly visible nucleolus) area, neuron soma long axis length, perimeter, area of neuronal nuclei and neuron soma form factor were measured with the aid of computer images analyzing program "Sigma Scan Pro 5.0". Also, the neuronal density and the area occupied by nerve cells per ganglion section were calculated. The relative frequency of satellite cells, in close contact with nerve cell soma, was estimated. Based on the data of this study, we concluded that the area of ganglia, neurons and their nuclei increased with age. Neuronal packing density significantly decreased, but the area occupied by nerve cells within the ganglia decreased non-significantly. Satellite cells were more numerous nearby ganglion n...

Research paper thumbnail of Spectroscopic studies of the human heart conduction system ex vivo: Implication for optical visualization

Journal of Photochemistry and Photobiology B: Biology, 2008

Research paper thumbnail of Spectroscopic studies of the human heart conduction system ex vivo: Implication for optical visualization

Journal of Photochemistry and Photobiology B: Biology, 2008

Research paper thumbnail of Imaging of histological sections of the human intestine by multimodal CARS microscope

Lithuanian Journal of Physics, 2012

Research paper thumbnail of Quantification of myocardial fibrosis by digital image analysis and interactive stereology

Background: Cardiac fibrosis disrupts the normal myocardial structure and has a direct impact on ... more Background: Cardiac fibrosis disrupts the normal myocardial structure and has a direct impact on heart function and survival. Despite already available digital methods, the pathologist's visual score is still widely considered as ground truth and used as a primary method in histomorphometric evaluations. The aim of this study was to compare the accuracy of digital image analysis tools and the pathologist's visual scoring for evaluating fibrosis in human myocardial biopsies, based on reference data obtained by point counting performed on the same images.

Research paper thumbnail of Proton Motor unveils new-generation 30 kW PM400 fuel cell stack

Research paper thumbnail of Editorial Board

Research paper thumbnail of Quantification of myocardial fibrosis by digital image analysis and interactive stereology

Background: Cardiac fibrosis disrupts the normal myocardial structure and has a direct impact on ... more Background: Cardiac fibrosis disrupts the normal myocardial structure and has a direct impact on heart function and survival. Despite already available digital methods, the pathologist's visual score is still widely considered as ground truth and used as a primary method in histomorphometric evaluations. The aim of this study was to compare the accuracy of digital image analysis tools and the pathologist's visual scoring for evaluating fibrosis in human myocardial biopsies, based on reference data obtained by point counting performed on the same images.

Research paper thumbnail of Index

Research paper thumbnail of Non-Ischemic Dilated Cardiomyopathy: Biopsy Proved Markers of Disease Sub-Entities

The Journal of Heart and Lung Transplantation, 2014

Research paper thumbnail of Proton Motor unveils new-generation 30 kW PM400 fuel cell stack

Research paper thumbnail of Editorial Board

Research paper thumbnail of Quantification of myocardial fibrosis by digital image analysis and interactive stereology

Background: Cardiac fibrosis disrupts the normal myocardial structure and has a direct impact on ... more Background: Cardiac fibrosis disrupts the normal myocardial structure and has a direct impact on heart function and survival. Despite already available digital methods, the pathologist's visual score is still widely considered as ground truth and used as a primary method in histomorphometric evaluations. The aim of this study was to compare the accuracy of digital image analysis tools and the pathologist's visual scoring for evaluating fibrosis in human myocardial biopsies, based on reference data obtained by point counting performed on the same images.

Research paper thumbnail of Spectroscopic studies of the human heart conduction system ex vivo: Implication for optical visualization

Journal of Photochemistry and Photobiology B: Biology, 2008

Fluorescence excitation and emission spectra of the heart tissues specimens have been measured ex... more Fluorescence excitation and emission spectra of the heart tissues specimens have been measured ex vivo with the aim of finding out the optical differences characteristic for the human heart conduction system (the His bundle) and ventricular myocardium.

Research paper thumbnail of M.539 Detection of Chlamydia pneumoniae in atherosclerothic tissue and investigation of serological status in patients with chronic atherosclerosis

Atherosclerosis, 2004

Objectives: Inflammatory factors together with classical risk factors ale important in the develo... more Objectives: Inflammatory factors together with classical risk factors ale important in the development of atherosclerosis. Chronic inflammation developed in at'terial wall could be like a response promoted by microol~ ganisms. Many infectious agents are investigated in order to establish thehethiopathogenetical role in the process of atherosclerosis but Chlamydia pneumoniae has the strongest implication. The potential role of this agent is being investigated in seroepidemiological, experimental, atherosclerothic tissue studies and clinical trials with antibiotics.

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