Ebubekir Ceylan - Academia.edu (original) (raw)

Papers by Ebubekir Ceylan

SUMMARY The purpose of this study was to investigate the effects of PPARα agonist on metabolic pa... more SUMMARY The purpose of this study was to investigate the effects of PPARα agonist on metabolic parameters in naturally Fasciola -infected sheep. Twenty sheep with fasciolosis were allotted in 2 equal groups according to the received treatment (triclabendazole/levamisole in the group I and triclabendazole/levamisole + PPARa agonist (2-methyl-2-phenoxy-propionic acid) in the group II) and the haematological and biochemical parameters were assessed before the treatment and 7, 14 and 28 days after and were compared to control values determined from 10 healthy sheep. As expected, fasciolosis has induced an anaemia evidenced by low haematocrit and low haemoglobinemia coupled to eosinophilia and to a moderate lymphopenia, severe liver damage characterised by hepatocyte degenerescence (significant increases in serum AST and GDH activities) and bile duct obstruction (significant increases in serum GGT activity and in serum bile acid concentrations) leading to impairement in liver metabolic f...

Van Veterinary Journal, 2023

Bu olgu sunumunda, plevral efüzyon ile karakterize vakalarda ayırıcı tanıyı koymakta veteriner he... more Bu olgu sunumunda, plevral efüzyon ile karakterize vakalarda ayırıcı tanıyı koymakta veteriner hekimlere yardımcı olmak ve rutinde tercih edilen geniş spektrumlu antibiyotik kullanımı sonucunda yanıt alınamadığı durumlarda bakteri identifikasyonu ve antibiyogram analizinin önemini vurgulayarak klinisyenlere tedavide izlenecek yollara dair yardımcı olması hedeflenmiştir. Bu olgunun materyalini toraks radyografisinde plevral efüzyon varlığı tespit edilmiş, dispne, dilde morarma, yüksek ateş ve ağrılı oturuş şikayetleri olan 1,5 yaşlı, Scottish Fold ırkı, erkek bir kedi oluşturmaktadır.Efüzyon örneğinin serolojik incelemesinde Feline Coronavirus pozitif sonucu üzerine Immuncomb FCoV IgG antikor titre testi bakılmış olup S2 düşük pozitif olduğu görülmüştür. Hastalığın klinik seyri ve diğer laboratuvar bulguları Feline Enfeksiyöz Peritonitis hastalığının efüziv formu ile paralel gitmediği için ayırıcı tanı amacıyla alınan efüzyonun sitolojik olarak incelenmesi uygun görülmüştür. Yapılan ...

ÖZET Bu çalışma, klinik olarak sağlıklı olduğu belirlenen 20 Siirt kıl keçisinde bazı biyokimyasa... more ÖZET Bu çalışma, klinik olarak sağlıklı olduğu belirlenen 20 Siirt kıl keçisinde bazı biyokimyasal parametrelerin, doğum öncesi ve doğum sonrası dönemlerdeki değişiklikleri belirlemek amacıyla planlandı. Gebeliğin yaklaşık olarak son haftasında ve doğumdan sonraki 7. günde V. jugularis’ten kan örnekleri toplandı. Toplanan örneklerde kan serumunda glikoz, üre, BUN, total protein, albümin, kolesterol ve trigliserit konsantrasyonları ve ALT, AST ve ALP enzimlerinin aktiviteleri ölçüldü. Sonuç olarak, ALP enzim aktivitesi, total protein ve kolesterol miktarlarının doğumdan sonra önemli oranda arttığı (p<0.05), diğer parametrelerde ise farklılıklar görülmesine rağmen, bu değişiklilerin istatistiksel olarak anlamlı olmadığı saptandı.

Indian Veterinary Journal, 2003

vfdergi.yyu.edu.tr

Indian Journal of Animal Research, 2014

The detection of genomic regions under positive selection is one of the important topics in popul... more The detection of genomic regions under positive selection is one of the important topics in population genetics. The objective of the present study was to identify the genomic regions that have been under natural or artificial selection in Afshari and Moghani sheep breeds. Seventy-five samples from Afshari (N=41) and Moghani (N=34) breeds have been genotyped using the Illumina Ovine SNP50K BeadChip. Unbiased method of population differentiation index (Theta) was used to detect the positive selection signatures using Lokern R package. The results of this study revealed 16 genetic regions on chromosomes 2, 3, 4, 8, 9, 13, 15, 22 and 26 where have been under positive selection in these two Iranian sheep breeds. A majority of the genes were involved in signal transduction pathways in a wide variety of cellular and biochemical processes. In particular, selection signatures were identified spanning several genes that directly or indirectly influenced pigmentation (EDN3, BNC2), skeletal morphology and body size (ALX4, EXT2, BMP2), metabolic regulation (PPP1R3D) and immune response (IL2RB). The results of the present study and identified genomic regions suggest that the selection during the evolution and adaptation to the different environments and geographical conditions led to population differentiation in Afshari and Moghani breeds. In conclusion, finding of this study can play an important role in tracing the genomic regions associated with the distinctive traits of these two indigenous breeds.

Bu çalışmada, 20 adet vekuronyum grubu, 20 adet de rokuronyum grubu olmak üzere toplam 40 adet so... more Bu çalışmada, 20 adet vekuronyum grubu, 20 adet de rokuronyum grubu olmak üzere toplam 40 adet sokak köpeği kullanıldı. Rokuronyum 0.25 ve 0.5 mg/kg'hk dozlarda, vekuronyum ise 0.06 ve 0.1 mg/kg'hk dozlarda kullanıldı. Bu ilaçların etki başlama ve etki süreleri ile uygulama öncesi, 15. dakikası ve- sonrası kalp atım sayıları, vücut ışılan ve oksijen saturasyon değerlerine bakıldı. Her iki grupta da vücut ısısında hafif azalma ve oksijen saturasyon değerlerinde hafif artış gözlendi. Kalp atım sayısına bakıldığında rokuronyum grubunda yüksek dozlarda artış, vekuronyum grubunda ise bazı vakalarda bradikardiye varan bir azalma gözlendi. Sonuç olarak kısa süreli entübasyon gerektiren durumlarda rokuronyumun, uzun süreli kas gevşemesi istenen olgularda vekuronyumun güvenli bir şekilde kullanılabileceği kanısına varıldı.In this study, 20 dogs for rocuronium group, 20 dogs for vecuronium group totally 40 dogs were used. Rocuronium was used at the dose of 0.25 and 0.50 mg/kg; Vecuron...

TURKISH JOURNAL OF VETERINARY AND ANIMAL SCIENCES

Ankara Üniversitesi Veteriner Fakültesi Dergisi, 2021

The aim of this study was to determine dynamic thiol-disulphide homeostasis (TDH) parameters and ... more The aim of this study was to determine dynamic thiol-disulphide homeostasis (TDH) parameters and ischemia modified albumin (IMA) levels in calves with neonatal diarrhea and compare with healthy controls. A total of 50 calves were included in the study. There were 25 calves in both diarrhea and healthy groups. Serum native thiol, total thiol, disulfide and IMA amounts were measured using new methods. Native thiol (P=0.025) and total thiol (P=0.041) values decreased significantly in calves with neonatal diarrhea compared to the healthy control group. Disulphide (P= 0.133), disulphide/native thiol ratio (P=0.001) and IMA (P=0.0018) parameters were lower in healthy group, and the difference between the two groups was significant for the parameters other than disulphide. This study shows that TDH is impaired in neonatal calf diarrhea and IMA levels are increased due to oxidative stress.

In the present study the role of Zn, Cu and thyroid hormone concentrations in the heifers having ... more In the present study the role of Zn, Cu and thyroid hormone concentrations in the heifers having retardation of the growth problem were aimed to investigate. In this study, 11 Eastern Anatolian Red heifers weighing 35-50 kg body weight (test group) and 6 Eastern Anatolian Red heifers in normal body weight (80-100 kg) (control group) aged between 6-12 months brought to the

The Open Clinical Biochemistry Journal, 2018

Objective: Lycopene is a carotenoid with anti-inflammatory and antioxidant properties. The aim of... more Objective: Lycopene is a carotenoid with anti-inflammatory and antioxidant properties. The aim of this study was to determine the effects of lycopene on oxidative DNA damage levels in experimental diabetic rats. Subjects and Methods: Four experimental groups, each consisting of 7 rats, were prepared as Controls, Diabetes (D), Lycopene-treated diabetes (DL) and Lycopene (L). STZ (45 mg/kg) was administered to the diabetic groups intraperitoneally in a single dose. Lycopene was administered to the L and DL groups (10 mg lycopene/kg/day). The test procedure continued for four weeks. To understand the occurrence of diabetic conditions, serum glucose and HbA1c% in the whole blood were determined. The 8-OHdG levels, a marker of oxidative DNA damage, were determined in the blood serum. Results: Blood glucose and HbA1c% were higher in the DL group than in the control group and L group (p <0.05) and lower in the D group (p <0.05). 8-OHdG levels were higher in D group than the other gro...

Indian Veterinary Journal, 2006

Indian Veterinary Journal, 2004

Veterinarski Arhiv, 2003

Pseudopericarditis has been used to describe jugular engorgement and oedema of the brisket and ve... more Pseudopericarditis has been used to describe jugular engorgement and oedema of the brisket and ventral abdominal wall. Similar symptoms can be seen in cattle with traumatic pericarditis. Pressure caused by tumours, abscesses, Echinococcus cysts, swollen lymph nodes resulting from tuberculosis and leukosis, one-sided pleuritis and diaphragmatic hernia to the base of cranial and caudal vena cava returning blood to the heart have been reported to cause pseudopericarditis in cattle. These mediastinal lymph nodes may also be swollen due to theileriosis and cause pressure on the v. cava. This study aims to describe the clinical, haematological and electrocardiographical findings of a pseudopericarditis case in a cow caused by theileriosis, and to add the disease into the aetiology of pseudopericarditis.

Objective: This study was carried out to determine the prognostic importance of troponin enzyme l... more Objective: This study was carried out to determine the prognostic importance of troponin enzyme levels in lambs with White Muscle Disease (WMD). Materials and Methods: This study consisted of 50 male and female lambs aged 0-3 months old, 30 of which had clinical white muscle disease (Group I) and 20 of which were healthy (Group II – Control Group). Group I was composed of lambs that showed clinical symptoms of the disease. The disease was also identified by laboratory analysis. The lambs in this group were treated and the course of the disease was followed for 15 days. Results: Compared with the control group, the Group I before treatment results were as follows: AST, LDH, CK, CK-MB, Troponin I and T (P<0.001) were high, while GSH-Px (P<0.001), SOD (P<0.01), Se (P<0.01), Retinol and Tocopherol were low. Compared with the control group, the Group I After Treatment results were as follows: AST, CK, Troponin T (P<0.001) were high, LDH (P<0.01) was high and GSH-Px (P&l...

Clinical Microbiology and Infection, 2009