Ekaterina Karteva - Academia.edu (original) (raw)

Papers by Ekaterina Karteva

Science & Research, 2019

Introduction Asymptomatic apical periodontitis (AAP) is a chronic inflammatory process mediated b... more Introduction Asymptomatic apical periodontitis (AAP) is a chronic inflammatory process mediated by a milieu of pro-inflammatory cytokines. TNF-α is a key mediator and a potent inducer of bone resorption and connective tissue degradation. The aim of the study was to examine TNF-α production by peripheral blood mononuclear cells (PBMCs) from patients with AAP and to explore its correlation to the lesions' characteristics. Materials and methods Patients (n=20) diagnosed with AAP were included in the study. The lesions' characteristics were assessed with limited-volume cone beam-computed tomography (limited FOV CBCT). PBMCs were isolated from peripheral blood samples obtained from each patient. The cells were cultivated in RPMI 1640 medium and stimulated with E.coli LPS. The supernatant was collected at the 24th and 48th-hour time point. TNF-α levels were detected by ELISA. Results TNF-α concentrations decreased significantly at the 48-h time point compared to the 24-hour time p...

INTRODUCTION The advent of Cone Beam Computed Tomography (CBCT) in endodontics has enhanced the d... more INTRODUCTION The advent of Cone Beam Computed Tomography (CBCT) in endodontics has enhanced the diagnosis of periapical radiolucencies and the assessment of endodontically treated teeth. AIM The purpose of this study was to assess the prevalence of periapical radiolucencies in a Bulgarian subpopulation and the quality of previous endodontic treatment using CBCT scans. MATERIALS AND METHODS This study included 2795 roots from 160 Large FOV CBCT which were evaluated by two independent examiners using two scoring systems: CBCT-PAI and PESS. RESULTS The inter-examiner agreement spanned from strong to almost perfect (0.892 and 0.983). The prevalence of periapical lesions according to the two scoring systems was 23.1% and 12.9 %, respectively. The prevalence of endodontically treated teeth was high (34.1%). Sixty-five percent of them presented with signs of periapical radiolucencies, while only 1.4% of all non-treated roots had a periapical lesion. A significant association between periap...

MATEC Web of Conferences, 2018

Endodontically treated teeth (ETT) are more susceptible to fracture during mastication. The aim o... more Endodontically treated teeth (ETT) are more susceptible to fracture during mastication. The aim of our study was to investigate the fracture resistance of premolars, restored with different techniques. Eighteen human premolars, extracted for orthodontic or periodontal reasons, were used. Mesio-occlusal cavities were prepared on all of them. They were divided into 3 groups according to the restoration method: with a cemented fiber post (FP), with a cemented metal post (MP) and without a post, but restored with a fiber reinforced composite core (FRC). After thermocycling, their fracture resistance was evaluated in a standard testing machine. The results were analyzed with one-way ANOVA and Tukey Honestly Significant Difference (HSD) tests (p<0.05). The fracture modes were also determined. The MP group showed the lowest fracture resistance rates and the highest number of unrestorable root fractures. In conclusion, teeth restored with FRC cores or FP show better survival rates than those restored with metal posts.

Journal of IMAB - Annual Proceeding (Scientific Papers)

Bio-Medical Materials and Engineering

Folia Medica

Background: The reduced fracture resistance in endodontically treated teeth requires the use of r... more Background: The reduced fracture resistance in endodontically treated teeth requires the use of radicular posts, with their advantages and disadvantages. Aim: To evaluate the clinical performance of teeth restored with or without radicular posts at 6 and 12 months. Materials and methods: The study included 22 patients who received endodontic therapy on premolars with a loss of one or two proximal walls. The premolars were divided into groups according to the restoration method: metal post group (MP), fiber post group (FP), and no post group (NP). For the NP group, a dentinal core of fiber-reinforced composite was used. The McNemar test, marginal homogeneity test and Kruskal-Wallis test were used in the statistical analysis. At the 6 and 12 month recall, both the direct composite restorations and the integrity of the post systems were assessed. Results: At 6-month recall assessment, there was no statistically significant difference in the categories of ‘appropriate colour’, ‘secondar...

Science & Research, 2019

Introduction Asymptomatic apical periodontitis (AAP) is a chronic inflammatory process mediated b... more Introduction Asymptomatic apical periodontitis (AAP) is a chronic inflammatory process mediated by a milieu of pro-inflammatory cytokines. TNF-α is a key mediator and a potent inducer of bone resorption and connective tissue degradation. The aim of the study was to examine TNF-α production by peripheral blood mononuclear cells (PBMCs) from patients with AAP and to explore its correlation to the lesions' characteristics. Materials and methods Patients (n=20) diagnosed with AAP were included in the study. The lesions' characteristics were assessed with limited-volume cone beam-computed tomography (limited FOV CBCT). PBMCs were isolated from peripheral blood samples obtained from each patient. The cells were cultivated in RPMI 1640 medium and stimulated with E.coli LPS. The supernatant was collected at the 24th and 48th-hour time point. TNF-α levels were detected by ELISA. Results TNF-α concentrations decreased significantly at the 48-h time point compared to the 24-hour time p...

INTRODUCTION The advent of Cone Beam Computed Tomography (CBCT) in endodontics has enhanced the d... more INTRODUCTION The advent of Cone Beam Computed Tomography (CBCT) in endodontics has enhanced the diagnosis of periapical radiolucencies and the assessment of endodontically treated teeth. AIM The purpose of this study was to assess the prevalence of periapical radiolucencies in a Bulgarian subpopulation and the quality of previous endodontic treatment using CBCT scans. MATERIALS AND METHODS This study included 2795 roots from 160 Large FOV CBCT which were evaluated by two independent examiners using two scoring systems: CBCT-PAI and PESS. RESULTS The inter-examiner agreement spanned from strong to almost perfect (0.892 and 0.983). The prevalence of periapical lesions according to the two scoring systems was 23.1% and 12.9 %, respectively. The prevalence of endodontically treated teeth was high (34.1%). Sixty-five percent of them presented with signs of periapical radiolucencies, while only 1.4% of all non-treated roots had a periapical lesion. A significant association between periap...

MATEC Web of Conferences, 2018

Endodontically treated teeth (ETT) are more susceptible to fracture during mastication. The aim o... more Endodontically treated teeth (ETT) are more susceptible to fracture during mastication. The aim of our study was to investigate the fracture resistance of premolars, restored with different techniques. Eighteen human premolars, extracted for orthodontic or periodontal reasons, were used. Mesio-occlusal cavities were prepared on all of them. They were divided into 3 groups according to the restoration method: with a cemented fiber post (FP), with a cemented metal post (MP) and without a post, but restored with a fiber reinforced composite core (FRC). After thermocycling, their fracture resistance was evaluated in a standard testing machine. The results were analyzed with one-way ANOVA and Tukey Honestly Significant Difference (HSD) tests (p<0.05). The fracture modes were also determined. The MP group showed the lowest fracture resistance rates and the highest number of unrestorable root fractures. In conclusion, teeth restored with FRC cores or FP show better survival rates than those restored with metal posts.

Journal of IMAB - Annual Proceeding (Scientific Papers)

Bio-Medical Materials and Engineering

Folia Medica

Background: The reduced fracture resistance in endodontically treated teeth requires the use of r... more Background: The reduced fracture resistance in endodontically treated teeth requires the use of radicular posts, with their advantages and disadvantages. Aim: To evaluate the clinical performance of teeth restored with or without radicular posts at 6 and 12 months. Materials and methods: The study included 22 patients who received endodontic therapy on premolars with a loss of one or two proximal walls. The premolars were divided into groups according to the restoration method: metal post group (MP), fiber post group (FP), and no post group (NP). For the NP group, a dentinal core of fiber-reinforced composite was used. The McNemar test, marginal homogeneity test and Kruskal-Wallis test were used in the statistical analysis. At the 6 and 12 month recall, both the direct composite restorations and the integrity of the post systems were assessed. Results: At 6-month recall assessment, there was no statistically significant difference in the categories of ‘appropriate colour’, ‘secondar...