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Papers by Eliane Mancuzo

Research paper thumbnail of A espirometria na avalia��o pr� e p�s-transplante de medula �ssea

Research paper thumbnail of Estudo comparativo entre uma medida isolada da circunferência abdominal e o aumento da resistência ao fluxo sanguíneo na artéria umbilical, no diagnóstico do crescimento intra-uterino retardado

J Bras Ginecol, Oct 1, 1996

Resumo: Os autores realizaram um estudo prospectivo com 174 pacientes de baixo risco onde compara... more Resumo: Os autores realizaram um estudo prospectivo com 174 pacientes de baixo risco onde compararam a medida isolada da circunferência abdominal eo aumento da resistência do fluxo sanguíneo da artéria umbilical para diagnóstico de crescimento intra-...

Research paper thumbnail of Cálculo ultra-sonográfico do peso fetal utilizando parâmetros biométricos distintos em faixas de peso diferentes

J Bras Ginecol, Feb 1, 1997

... Autor: Viegas, Mário Barreto; Fernandes, Ana Lucia Valadares; Hein, Monica; Mancuzo, Eliane V... more ... Autor: Viegas, Mário Barreto; Fernandes, Ana Lucia Valadares; Hein, Monica; Mancuzo, Eliane Viana; Mota, Cristiana Sampaio ... Nestas equaçöes säo usados diferentes parâmetros biométricostais como diâmetro biparietal, circunferência cefálica, circunferência abdominal e ...

Research paper thumbnail of Estudo comparativo eentre os índices dopplervelocimétrico obtidos em diferentes locais de insonaçäo do cordäo umbilical

J Bras Ginecol, Sep 1, 1997

Resumo: Os autores fizeram um estudo prospectivo onde analisaram e compararam o índice de resistê... more Resumo: Os autores fizeram um estudo prospectivo onde analisaram e compararam o índice de resistência da artéria umbilical obtido em pontos extremos do cordÝo. A análise estatística mostrou significância importante, ou seja, o índice de resistência da artéria ...

Research paper thumbnail of Artigo Original A espirometria na avaliação pré e pós-transplante de medula óssea* Pre-operative and post-operative spirometry in bone marrow transplant patients

Objetivo: Analisar os resultados da espirometria de pacientes submetidos a transplante de medula ... more Objetivo: Analisar os resultados da espirometria de pacientes submetidos a transplante de medula óssea e verificar sua importância na detecção de complicações pulmonares e sua correlação com a evolução dos pacientes. Métodos: Foram analisados retrospectivamente os resultados da espirometria em 120 pacientes, maiores de doze anos, de ambos os sexos, e comparados com o tipo de transplante de medula óssea, doença de base, sorologia para citomegalovírus, fonte de células para o transplante, tabagismo, infecção pulmonar, doença pulmonar prévia, duração da doença hematológica, quimioterapia utilizada, regime de condicionamento, doença do enxerto contra o hospedeiro aguda e crônica e óbito. Resultados: Dezesseis pacientes apresentaram alterações da espirometria antes do transplante, sendo 5% com obstrução pura, 5,8% com restrição pura e 2,5% com obstrução com redução da capacidade vital. Após o transplante 29 pacientes apresentaram alterações desses exames. A chance de alteração da espirometria foi maior nos pacientes com doença do enxerto contra o hospedeiro aguda (p = 0,02), idade menor que 30 anos (p = 0,02), sexo feminino (p = 0,02) e naqueles que receberam células tronco (p = 0,01). As presenças de doença pulmonar prévia e doença do enxerto contra o hospedeiro crônica associaram-se com aumento da mortalidade. Alterações prévias da espirometria não estiveram relacionadas com o óbito pós-transplante. Conclusão: As alterações detectadas na espirometria não foram capazes de predizer a ocorrência de complicações pulmonares e óbito pós-transplantes. Também não foram determinantes para a não realização do procedimento. A espirometria simples realizada na avaliação desses pacientes parece ter pouca importância prática.

Research paper thumbnail of Simone

Research paper thumbnail of Chronic symptoms and pulmonary dysfunction in post-tuberculosis Brazilian patients

The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases, Jan 5, 2015

Questionnaire and spirometry were applied to post-tuberculosis indigenous and non-indigenous indi... more Questionnaire and spirometry were applied to post-tuberculosis indigenous and non-indigenous individuals from Dourados, Brazil, to investigate the prevalence of chronic respiratory symptoms and pulmonary dysfunction. This was a cross-sectional study in cured tuberculosis individuals as reported in the National System on Reportable Diseases (SINAN) from 2002 to 2012. One hundred and twenty individuals were included in the study and the prevalence of chronic respiratory symptoms was 45% (95% CI, 34-59%). Respiratory symptoms included cough (28%), sputum (23%), wheezing (22%) and dyspnea (8%). These symptoms were associated with alcoholism, AOR: 3.1 (1.2-8.4); less than 4 years of schooling, AOR: 5.0 (1.4-17.7); and previous pulmonary diseases, AOR: 5.4 (1.7-17.3). Forty-one percent (95% CI, 29-56) had pulmonary disorders, of which the most prevalent were obstructive disorders (49%), followed by obstructive disorder with reduced forced vital capacity disorders (46%) and restrictive dis...

Research paper thumbnail of Effect of pulmonary rehabilitation on exercising tolerance in patients with advanced lung disease in waiting list for lung transplant

Revista Médica de Minas Gerais, 2015

Research paper thumbnail of Pre-transplant aerobic capacity and prolonged hospitalization after liver transplantation

GE Portuguese Journal of Gastroenterology, 2015

ABSTRACT Patients with end stage liver disease (ESLD) referred for liver transplantation (LT) are... more ABSTRACT Patients with end stage liver disease (ESLD) referred for liver transplantation (LT) are forwarded to pulmonary evaluation before being operated. ESLD is associated with muscle wasting, reduced exercise tolerance and aerobic capacity.

Research paper thumbnail of Testes de função pulmonar e mortalidade após o transplante de células-tronco hematopoiéticas: pulmonary function tests and post-transplant mortality

Jornal Brasileiro de Pneumologia, 2011

Testes de função pulmonar e mortalidade após o transplante de células-tronco hematopoiéticas* Hem... more Testes de função pulmonar e mortalidade após o transplante de células-tronco hematopoiéticas* Hematopoietic stem cell transplantation: pulmonary function tests and post-transplant mortality Eliane Viana Mancuzo, Nilton Alves de Rezende Resumo Objetivo: Verificar se os resultados dos testes de função pulmonar realizados em pacientes submetidos a transplante de células-tronco hematopoiéticas (TCTH) estão associados com a mortalidade após o procedimento. Métodos: Estudo prospectivo no qual foram incluídos pacientes maiores de 15 anos submetidos a TCTH alogênico, entre janeiro de 2007 e março de 2008, no Hospital das Clínicas da Universidade Federal de Minas Gerais, em Belo Horizonte (MG), e que realizaram espirometria, medida de volumes pulmonares e medida de DLCO antes do TCTH. Os testes foram repetidos seis meses, um ano e dois anos após TCTH. Para a análise de sobrevida, foram utilizados o método de Kaplan-Meier e testes de log-rank bicaudal. O risco relativo (RR) e IC95% foram calculados por meio do ajuste do modelo de riscos proporcionais de Cox. O modelo de regressão de Cox foi utilizado na análise multivariada. Resultados: Dos 54 pacientes incluídos, 40 (74,1%) apresentaram resultados normais de função pulmonar antes do TCTH. Ocorreram 23 óbitos (42,6%) em dois anos após o TCTH, sendo que 19 aconteceram antes de 100 dias. Dos 23 óbitos, 11 (47,8%) foram por septicemia e 10 (43,4%) por insuficiência respiratória aguda associada à septicemia. As únicas variáveis que mostraram associação significativa com mortalidade após TCTH foram alteração na espirometria antes do TCTH (RR = 3,2; p = 0,016) e doador não aparentado (RR = 9,0; p < 0,001). Conclusões: A realização da espirometria antes do TCTH fornece valores basais para comparações futuras. Alterações nesses resultados indicam um maior risco de mortalidade após o TCTH, embora esses não contraindicam o procedimento. Descritores: Transplante de células-tronco hematopoéticas/mortalidade; Testes de função respiratória; Seleção do doador.

Research paper thumbnail of A espirometria na avaliação pré e pós-transplante de medula óssea

Jornal Brasileiro de Pneumologia, 2007

... Eliane Viana Mancuzo1, Walace Espada da Silva2, Nilton Alves de Rezende3 ... Observamos emnos... more ... Eliane Viana Mancuzo1, Walace Espada da Silva2, Nilton Alves de Rezende3 ... Observamos emnossa análise uma tendência de associação entre alteração da espirometria pós-transplante e pacientes ... Quintas-Cardama A, Perez-Encinas M, Gonzalez S, Bendana A, Bello JL. ...

Research paper thumbnail of Complicações pulmonares não infecciosas após transplante de células-tronco hematopoiéticas

Revista Portuguesa de Pneumologia (English Edition), 2010

R e v i s t a P o r t u g u e s a d e P n e u m o l o g i a 815 Vol XVI N.º 5 Setembro/Outubro 2010

Research paper thumbnail of Tratamento da hipertensão pulmonar esquistossomótica

Jornal Brasileiro de Pneumologia, 2011

Research paper thumbnail of Artigo Original A espirometria na avaliação pré e pós-transplante de medula óssea* Preoperative and post-operative spirometry in bone marrow transplant patients

Objective: To analyze the spirometry findings in patients undergoing bone marrow transplant, dete... more Objective: To analyze the spirometry findings in patients undergoing bone marrow transplant, determining the importance of such findings in predicting postoperative pulmonary complications and looking for correlations with postoperative outcomes. Methods: The spirometry findings in 120 male and female patients, all above the age of 12, were evaluated retrospectively and compared in terms of the following parameters: the type of bone marrow transplant; the underlying disease; cytomegalovirus serology; source of the transplanted cells; smoking; pulmonary infection; history of lung disease; duration of the hematological disease; chemotherapy employed; conditioning regimen; acute or chronic rejection of the transplant; and post-operative mortality. Results: In the pre-operative spirometry, 16 patients (13.3%) presented alterations: 6 (5%) presented pure obstruction; 7 (5.8%) presented pure restriction; and 3 (2.5%) presented obstruction accompanied by a reduction in vital capacity. In t...

Research paper thumbnail of Effects of noninvasive ventilation on dynamic hiperinflation of patients with COPD during activities of daily living with upper limbs

Revista Brasileira de Fisioterapia, 2012

Patients with chronic obstructive pulmonary disease (COPD) complain of dyspnea on activities of d... more Patients with chronic obstructive pulmonary disease (COPD) complain of dyspnea on activities of daily living (ADLs) with the upper limbs. Dynamic hyperinflation (DH) is one of the ventilatory mechanisms that may contribute towards dyspnea. To minimize the DH it is indicated the use of noninvasive ventilation (NIV). To verify whether there is DH and dyspnea during the performance of ADL with the upper limbs with and without the use of NIV. 32 patients with moderate-to-severe COPD, aged 54 to 87 years (mean 69.4, SD 7.4) were evaluated. The subjects lift up containers weighing between 0.5 and 5.0 kg over a five-minute period, starting from the waist level and putting them onto a shelf located above head height, with and without the use of NIV (BiPAP®; IPAP 10cmH₂O; EPAP 4 cmH₂O). The inspiratory capacity (IC) and dyspnea (Borg scale) were evaluated on all the patients. The IC was measured before and after simulation of the ADL. In order to analyze the data, Student&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;#39;s t test for dependent samples and the Wilcoxon test were used. There were statistically significant reductions in IC after the ADL with and without NIV (p=0.01). The dyspnea increased after the ADL with and without the NIV, however between both interventional procedures protocols no between-group difference was observed. The simulation of an ADL with the upper limbs resulted in an increase in DH and dyspnea. The NIV supplied with pre-established pressure was not enough to prevent the DH and dyspnea.

Research paper thumbnail of Efeitos da ventilação não-invasiva sobre a hiperinsuflação dinâmica de pacientes com DPOC durante atividade da vida diária com os membros superiores

Brazilian Journal of Physical Therapy, 2012

Page 1. ARTIGO ORIGINAL ISSN 1413-3555 Rev Bras Fisioter, São Carlos, v. 16, n. 1, p. 61-7, jan./... more Page 1. ARTIGO ORIGINAL ISSN 1413-3555 Rev Bras Fisioter, São Carlos, v. 16, n. 1, p. 61-7, jan./fev. 2012 ©Revista Brasileira de Fisioterapia Efeitos da ventilação não-invasiva sobre a hiperinsuflação dinâmica de pacientes com DPOC durante atividade da vida diária com ...

Research paper thumbnail of Non-infectious pulmonary complications after the hematoppoietic stem cell trasplantation

Pulmonary complications are important cause of mortality and morbidity after hematopoietic stem c... more Pulmonary complications are important cause of mortality and morbidity after hematopoietic stem cell transplantation, in 30% to 60% of the patients. Improvements in prophylaxis and treatment of infectious complications have been increasing the rate of non-infectious complications. Early diagnosis and treatment of those complications can significantly change the evolution of hematopoietic stem cell transplantation receptors. The objective of this study is to review the most frequent non-infection complications associated to hematopoietic stem cell transplantation since the first bone marrow transplantation performed in 1957. A systematic literature review was performed, using the PICO strategy to ask the questions. The descriptors hematopoietic stem cell transplantation, non-infectious pulmonary complications, systematic review, in portuguese and their english correspondents, were used to access the following databases: MEDLINE, EBM, Embase, Cocrane Library, LILACS and SciELO. In this review, 263 studies were identified, from which 31 were selected for full analyzis. The non-infection pulmonary complications most frequently found were: bronchiolitis obliterans, bronchiolitis obliterans organizing pneumonia, pulmonary edema, idiopathic pneumonia syndrome, delayed pulmonary toxicity syndrome, diffuse alveolar hemorrhage, engrafment syndrome and pulmonary cytolitic thrombi.

Research paper thumbnail of Six-minute walk test and respiratory muscle strength in patients with uncontrolled severe asthma: a pilot study

Objective: To evaluate respiratory muscle strength and six-minute walk test (6MWT) variables in p... more Objective: To evaluate respiratory muscle strength and six-minute walk test (6MWT) variables in patients with
uncontrolled severe asthma (UCSA). Methods: This was a cross-sectional study involving UCSA patients followed
at a university hospital. The patients underwent 6MWT, spirometry, and measurements of respiratory muscle
strength, as well as completing the Asthma Control Test (ACT). The Mann-Whitney test was used in order to analyze 6MWT variables, whereas the Kruskal-Wallis test was used to determine whether there was an association between the use of oral corticosteroids and respiratory muscle strength. Results: We included 25 patients. Mean FEV1 was 58.8 ± 21.8% of predicted, and mean ACT score was 14.0 ± 3.9 points. No significant difference was found between the median six-minute walk distance recorded for the UCSA patients and that predicted for healthy Brazilians (512 m and 534 m, respectively; p = 0.14). During the 6MWT, there was no significant
drop in SpO2. Mean MIP and MEP were normal (72.9 ± 15.2% and 67.6 ± 22.2%, respectively). Comparing the patients treated with at least four courses of oral corticosteroids per year and those treated with three or fewer, we found no significant differences in MIP (p = 0.15) or MEP (p = 0.45). Conclusions: Our findings suggest that UCSA patients are similar to normal subjects in terms of 6MWT variables and respiratory muscle strength. The use of oral corticosteroids has no apparent impact on respiratory muscle strength.
Keywords: Asthma; Exercise tolerance; Respiratory muscles.

Research paper thumbnail of A espirometria na avalia��o pr� e p�s-transplante de medula �ssea

Research paper thumbnail of Estudo comparativo entre uma medida isolada da circunferência abdominal e o aumento da resistência ao fluxo sanguíneo na artéria umbilical, no diagnóstico do crescimento intra-uterino retardado

J Bras Ginecol, Oct 1, 1996

Resumo: Os autores realizaram um estudo prospectivo com 174 pacientes de baixo risco onde compara... more Resumo: Os autores realizaram um estudo prospectivo com 174 pacientes de baixo risco onde compararam a medida isolada da circunferência abdominal eo aumento da resistência do fluxo sanguíneo da artéria umbilical para diagnóstico de crescimento intra-...

Research paper thumbnail of Cálculo ultra-sonográfico do peso fetal utilizando parâmetros biométricos distintos em faixas de peso diferentes

J Bras Ginecol, Feb 1, 1997

... Autor: Viegas, Mário Barreto; Fernandes, Ana Lucia Valadares; Hein, Monica; Mancuzo, Eliane V... more ... Autor: Viegas, Mário Barreto; Fernandes, Ana Lucia Valadares; Hein, Monica; Mancuzo, Eliane Viana; Mota, Cristiana Sampaio ... Nestas equaçöes säo usados diferentes parâmetros biométricostais como diâmetro biparietal, circunferência cefálica, circunferência abdominal e ...

Research paper thumbnail of Estudo comparativo eentre os índices dopplervelocimétrico obtidos em diferentes locais de insonaçäo do cordäo umbilical

J Bras Ginecol, Sep 1, 1997

Resumo: Os autores fizeram um estudo prospectivo onde analisaram e compararam o índice de resistê... more Resumo: Os autores fizeram um estudo prospectivo onde analisaram e compararam o índice de resistência da artéria umbilical obtido em pontos extremos do cordÝo. A análise estatística mostrou significância importante, ou seja, o índice de resistência da artéria ...

Research paper thumbnail of Artigo Original A espirometria na avaliação pré e pós-transplante de medula óssea* Pre-operative and post-operative spirometry in bone marrow transplant patients

Objetivo: Analisar os resultados da espirometria de pacientes submetidos a transplante de medula ... more Objetivo: Analisar os resultados da espirometria de pacientes submetidos a transplante de medula óssea e verificar sua importância na detecção de complicações pulmonares e sua correlação com a evolução dos pacientes. Métodos: Foram analisados retrospectivamente os resultados da espirometria em 120 pacientes, maiores de doze anos, de ambos os sexos, e comparados com o tipo de transplante de medula óssea, doença de base, sorologia para citomegalovírus, fonte de células para o transplante, tabagismo, infecção pulmonar, doença pulmonar prévia, duração da doença hematológica, quimioterapia utilizada, regime de condicionamento, doença do enxerto contra o hospedeiro aguda e crônica e óbito. Resultados: Dezesseis pacientes apresentaram alterações da espirometria antes do transplante, sendo 5% com obstrução pura, 5,8% com restrição pura e 2,5% com obstrução com redução da capacidade vital. Após o transplante 29 pacientes apresentaram alterações desses exames. A chance de alteração da espirometria foi maior nos pacientes com doença do enxerto contra o hospedeiro aguda (p = 0,02), idade menor que 30 anos (p = 0,02), sexo feminino (p = 0,02) e naqueles que receberam células tronco (p = 0,01). As presenças de doença pulmonar prévia e doença do enxerto contra o hospedeiro crônica associaram-se com aumento da mortalidade. Alterações prévias da espirometria não estiveram relacionadas com o óbito pós-transplante. Conclusão: As alterações detectadas na espirometria não foram capazes de predizer a ocorrência de complicações pulmonares e óbito pós-transplantes. Também não foram determinantes para a não realização do procedimento. A espirometria simples realizada na avaliação desses pacientes parece ter pouca importância prática.

Research paper thumbnail of Simone

Research paper thumbnail of Chronic symptoms and pulmonary dysfunction in post-tuberculosis Brazilian patients

The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases, Jan 5, 2015

Questionnaire and spirometry were applied to post-tuberculosis indigenous and non-indigenous indi... more Questionnaire and spirometry were applied to post-tuberculosis indigenous and non-indigenous individuals from Dourados, Brazil, to investigate the prevalence of chronic respiratory symptoms and pulmonary dysfunction. This was a cross-sectional study in cured tuberculosis individuals as reported in the National System on Reportable Diseases (SINAN) from 2002 to 2012. One hundred and twenty individuals were included in the study and the prevalence of chronic respiratory symptoms was 45% (95% CI, 34-59%). Respiratory symptoms included cough (28%), sputum (23%), wheezing (22%) and dyspnea (8%). These symptoms were associated with alcoholism, AOR: 3.1 (1.2-8.4); less than 4 years of schooling, AOR: 5.0 (1.4-17.7); and previous pulmonary diseases, AOR: 5.4 (1.7-17.3). Forty-one percent (95% CI, 29-56) had pulmonary disorders, of which the most prevalent were obstructive disorders (49%), followed by obstructive disorder with reduced forced vital capacity disorders (46%) and restrictive dis...

Research paper thumbnail of Effect of pulmonary rehabilitation on exercising tolerance in patients with advanced lung disease in waiting list for lung transplant

Revista Médica de Minas Gerais, 2015

Research paper thumbnail of Pre-transplant aerobic capacity and prolonged hospitalization after liver transplantation

GE Portuguese Journal of Gastroenterology, 2015

ABSTRACT Patients with end stage liver disease (ESLD) referred for liver transplantation (LT) are... more ABSTRACT Patients with end stage liver disease (ESLD) referred for liver transplantation (LT) are forwarded to pulmonary evaluation before being operated. ESLD is associated with muscle wasting, reduced exercise tolerance and aerobic capacity.

Research paper thumbnail of Testes de função pulmonar e mortalidade após o transplante de células-tronco hematopoiéticas: pulmonary function tests and post-transplant mortality

Jornal Brasileiro de Pneumologia, 2011

Testes de função pulmonar e mortalidade após o transplante de células-tronco hematopoiéticas* Hem... more Testes de função pulmonar e mortalidade após o transplante de células-tronco hematopoiéticas* Hematopoietic stem cell transplantation: pulmonary function tests and post-transplant mortality Eliane Viana Mancuzo, Nilton Alves de Rezende Resumo Objetivo: Verificar se os resultados dos testes de função pulmonar realizados em pacientes submetidos a transplante de células-tronco hematopoiéticas (TCTH) estão associados com a mortalidade após o procedimento. Métodos: Estudo prospectivo no qual foram incluídos pacientes maiores de 15 anos submetidos a TCTH alogênico, entre janeiro de 2007 e março de 2008, no Hospital das Clínicas da Universidade Federal de Minas Gerais, em Belo Horizonte (MG), e que realizaram espirometria, medida de volumes pulmonares e medida de DLCO antes do TCTH. Os testes foram repetidos seis meses, um ano e dois anos após TCTH. Para a análise de sobrevida, foram utilizados o método de Kaplan-Meier e testes de log-rank bicaudal. O risco relativo (RR) e IC95% foram calculados por meio do ajuste do modelo de riscos proporcionais de Cox. O modelo de regressão de Cox foi utilizado na análise multivariada. Resultados: Dos 54 pacientes incluídos, 40 (74,1%) apresentaram resultados normais de função pulmonar antes do TCTH. Ocorreram 23 óbitos (42,6%) em dois anos após o TCTH, sendo que 19 aconteceram antes de 100 dias. Dos 23 óbitos, 11 (47,8%) foram por septicemia e 10 (43,4%) por insuficiência respiratória aguda associada à septicemia. As únicas variáveis que mostraram associação significativa com mortalidade após TCTH foram alteração na espirometria antes do TCTH (RR = 3,2; p = 0,016) e doador não aparentado (RR = 9,0; p < 0,001). Conclusões: A realização da espirometria antes do TCTH fornece valores basais para comparações futuras. Alterações nesses resultados indicam um maior risco de mortalidade após o TCTH, embora esses não contraindicam o procedimento. Descritores: Transplante de células-tronco hematopoéticas/mortalidade; Testes de função respiratória; Seleção do doador.

Research paper thumbnail of A espirometria na avaliação pré e pós-transplante de medula óssea

Jornal Brasileiro de Pneumologia, 2007

... Eliane Viana Mancuzo1, Walace Espada da Silva2, Nilton Alves de Rezende3 ... Observamos emnos... more ... Eliane Viana Mancuzo1, Walace Espada da Silva2, Nilton Alves de Rezende3 ... Observamos emnossa análise uma tendência de associação entre alteração da espirometria pós-transplante e pacientes ... Quintas-Cardama A, Perez-Encinas M, Gonzalez S, Bendana A, Bello JL. ...

Research paper thumbnail of Complicações pulmonares não infecciosas após transplante de células-tronco hematopoiéticas

Revista Portuguesa de Pneumologia (English Edition), 2010

R e v i s t a P o r t u g u e s a d e P n e u m o l o g i a 815 Vol XVI N.º 5 Setembro/Outubro 2010

Research paper thumbnail of Tratamento da hipertensão pulmonar esquistossomótica

Jornal Brasileiro de Pneumologia, 2011

Research paper thumbnail of Artigo Original A espirometria na avaliação pré e pós-transplante de medula óssea* Preoperative and post-operative spirometry in bone marrow transplant patients

Objective: To analyze the spirometry findings in patients undergoing bone marrow transplant, dete... more Objective: To analyze the spirometry findings in patients undergoing bone marrow transplant, determining the importance of such findings in predicting postoperative pulmonary complications and looking for correlations with postoperative outcomes. Methods: The spirometry findings in 120 male and female patients, all above the age of 12, were evaluated retrospectively and compared in terms of the following parameters: the type of bone marrow transplant; the underlying disease; cytomegalovirus serology; source of the transplanted cells; smoking; pulmonary infection; history of lung disease; duration of the hematological disease; chemotherapy employed; conditioning regimen; acute or chronic rejection of the transplant; and post-operative mortality. Results: In the pre-operative spirometry, 16 patients (13.3%) presented alterations: 6 (5%) presented pure obstruction; 7 (5.8%) presented pure restriction; and 3 (2.5%) presented obstruction accompanied by a reduction in vital capacity. In t...

Research paper thumbnail of Effects of noninvasive ventilation on dynamic hiperinflation of patients with COPD during activities of daily living with upper limbs

Revista Brasileira de Fisioterapia, 2012

Patients with chronic obstructive pulmonary disease (COPD) complain of dyspnea on activities of d... more Patients with chronic obstructive pulmonary disease (COPD) complain of dyspnea on activities of daily living (ADLs) with the upper limbs. Dynamic hyperinflation (DH) is one of the ventilatory mechanisms that may contribute towards dyspnea. To minimize the DH it is indicated the use of noninvasive ventilation (NIV). To verify whether there is DH and dyspnea during the performance of ADL with the upper limbs with and without the use of NIV. 32 patients with moderate-to-severe COPD, aged 54 to 87 years (mean 69.4, SD 7.4) were evaluated. The subjects lift up containers weighing between 0.5 and 5.0 kg over a five-minute period, starting from the waist level and putting them onto a shelf located above head height, with and without the use of NIV (BiPAP®; IPAP 10cmH₂O; EPAP 4 cmH₂O). The inspiratory capacity (IC) and dyspnea (Borg scale) were evaluated on all the patients. The IC was measured before and after simulation of the ADL. In order to analyze the data, Student&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;#39;s t test for dependent samples and the Wilcoxon test were used. There were statistically significant reductions in IC after the ADL with and without NIV (p=0.01). The dyspnea increased after the ADL with and without the NIV, however between both interventional procedures protocols no between-group difference was observed. The simulation of an ADL with the upper limbs resulted in an increase in DH and dyspnea. The NIV supplied with pre-established pressure was not enough to prevent the DH and dyspnea.

Research paper thumbnail of Efeitos da ventilação não-invasiva sobre a hiperinsuflação dinâmica de pacientes com DPOC durante atividade da vida diária com os membros superiores

Brazilian Journal of Physical Therapy, 2012

Page 1. ARTIGO ORIGINAL ISSN 1413-3555 Rev Bras Fisioter, São Carlos, v. 16, n. 1, p. 61-7, jan./... more Page 1. ARTIGO ORIGINAL ISSN 1413-3555 Rev Bras Fisioter, São Carlos, v. 16, n. 1, p. 61-7, jan./fev. 2012 ©Revista Brasileira de Fisioterapia Efeitos da ventilação não-invasiva sobre a hiperinsuflação dinâmica de pacientes com DPOC durante atividade da vida diária com ...

Research paper thumbnail of Non-infectious pulmonary complications after the hematoppoietic stem cell trasplantation

Pulmonary complications are important cause of mortality and morbidity after hematopoietic stem c... more Pulmonary complications are important cause of mortality and morbidity after hematopoietic stem cell transplantation, in 30% to 60% of the patients. Improvements in prophylaxis and treatment of infectious complications have been increasing the rate of non-infectious complications. Early diagnosis and treatment of those complications can significantly change the evolution of hematopoietic stem cell transplantation receptors. The objective of this study is to review the most frequent non-infection complications associated to hematopoietic stem cell transplantation since the first bone marrow transplantation performed in 1957. A systematic literature review was performed, using the PICO strategy to ask the questions. The descriptors hematopoietic stem cell transplantation, non-infectious pulmonary complications, systematic review, in portuguese and their english correspondents, were used to access the following databases: MEDLINE, EBM, Embase, Cocrane Library, LILACS and SciELO. In this review, 263 studies were identified, from which 31 were selected for full analyzis. The non-infection pulmonary complications most frequently found were: bronchiolitis obliterans, bronchiolitis obliterans organizing pneumonia, pulmonary edema, idiopathic pneumonia syndrome, delayed pulmonary toxicity syndrome, diffuse alveolar hemorrhage, engrafment syndrome and pulmonary cytolitic thrombi.

Research paper thumbnail of Six-minute walk test and respiratory muscle strength in patients with uncontrolled severe asthma: a pilot study

Objective: To evaluate respiratory muscle strength and six-minute walk test (6MWT) variables in p... more Objective: To evaluate respiratory muscle strength and six-minute walk test (6MWT) variables in patients with
uncontrolled severe asthma (UCSA). Methods: This was a cross-sectional study involving UCSA patients followed
at a university hospital. The patients underwent 6MWT, spirometry, and measurements of respiratory muscle
strength, as well as completing the Asthma Control Test (ACT). The Mann-Whitney test was used in order to analyze 6MWT variables, whereas the Kruskal-Wallis test was used to determine whether there was an association between the use of oral corticosteroids and respiratory muscle strength. Results: We included 25 patients. Mean FEV1 was 58.8 ± 21.8% of predicted, and mean ACT score was 14.0 ± 3.9 points. No significant difference was found between the median six-minute walk distance recorded for the UCSA patients and that predicted for healthy Brazilians (512 m and 534 m, respectively; p = 0.14). During the 6MWT, there was no significant
drop in SpO2. Mean MIP and MEP were normal (72.9 ± 15.2% and 67.6 ± 22.2%, respectively). Comparing the patients treated with at least four courses of oral corticosteroids per year and those treated with three or fewer, we found no significant differences in MIP (p = 0.15) or MEP (p = 0.45). Conclusions: Our findings suggest that UCSA patients are similar to normal subjects in terms of 6MWT variables and respiratory muscle strength. The use of oral corticosteroids has no apparent impact on respiratory muscle strength.
Keywords: Asthma; Exercise tolerance; Respiratory muscles.