Elio Berutti - Academia.edu (original) (raw)

Papers by Elio Berutti

Journal of Clinical Medicine, Aug 8, 2022

Applied Sciences

Background: The labial frenulum may be associated with traction on the marginal gingiva of the in... more Background: The labial frenulum may be associated with traction on the marginal gingiva of the incisors with resulting gingival recession, a condition known as “pull syndrome”. In this case, performing a frenulectomy at least 6 months before root covering surgery is necessary. Recently, tissue adhesives have been studied as a good alternative to conventional sutures. Methods: A 34-year-old female affected by pull syndrome of the central lower incisors underwent frenulectomy, and an n-hexyl-cyanoacrylate tissue adhesive was used to ensure wound closure. Results: The patient was instructed in hygiene maneuvers and rinsed with 0.12% chlorhexidine-based mouthwash for 15 days. The glue was partially removed at 7 days, and for the remaining, natural disposal time was expected. The wound healing process was complete after 15 days with minimal postoperative discomfort. Conclusion: This n-hexyl-cyanoacrylate surgical glue could be proposed as a viable alternative to conventional sutures duri...

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology, 2008

The purpose of this study was to evaluate the amounts of debris and smear layer remaining on cana... more The purpose of this study was to evaluate the amounts of debris and smear layer remaining on canal walls after preparation with ProTaper and Hero Shaper instruments in combination with NaOCl and EDTA irrigation in curved root canals. Study design. A total of 55 root canals were randomly divided into 2 instrumentation groups of 20 canals each and 1 negative control group of 15 canals. The canals in each of the 2 instrumentation groups were prepared with ProTaper or Hero Shaper instruments. Irrigation was performed with 5% NaOCl and 17% EDTA solutions. The control group was not instrumented. The remaining debris and smear layer were evaluated from scanning electron photomicrographs at ϫ200 and ϫ1,000 magnification taken in the coronal, middle, and apical thirds of the canals at both inner and outer canal walls. A 5-category scoring system for debris and smear layer was used. Statistical analysis was carried out using the Kruskal-Wallis and Mann-Whitney rank sum tests. Results. Completely clean root canals were not found in either instrumentation group. In the coronal and middle thirds, the canal walls of both instrumentation groups were clean, with no or only small areas of debris and smear layer. In the apical region, there were higher scores in terms of debris and smear layer in both instrumentation groups. No significant difference was found at the inner wall of the 2 instrumentation groups in terms of debris mean score. However, the outer canal walls prepared with ProTaper showed lower debris score compared with those prepared with Hero Shaper (P Ͻ 0.001). Concerning the smear layer, both the inner and outer canal walls prepared with ProTaper showed lower mean scores compared with those prepared with Hero Shaper (P Ͻ 0.001). Conclusions. Within the limitations of this study, both instruments in combination with NaOCl and EDTA irrigation produced a clean and debris-free canal surface in the coronal and middle thirds, but were unable to produce a canal surface free from debris and smear layer in the apical third. However, the canals prepared with ProTaper instruments showed smaller amounts of debris and smear layer remaining in the apical region. (Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2008;106:e63-e71)

Journal of Clinical Medicine

The aim was to evaluate the antibacterial efficacy and penetration depth into dentinal tubules of... more The aim was to evaluate the antibacterial efficacy and penetration depth into dentinal tubules of a solution of chitosan nanodroplets (NDs) loaded with Benzalkonium Chloride (BAK). Seventy-two human single-root teeth with fully formed apex were used. Cylindrical root dentin blocks were longitudinally sectioned and enlarged to a size of a Gates Glidden drill #4. After sterilization, root canals were infected with Enterococcus faecalis ATCC 29212 and further incubated for three weeks. Specimens were assigned to three experimental groups (n = 20), plus positive (n = 6) and negative (n = 6) controls. In the first group, irrigation was achieved with 2 mL of NDs solution loaded with BAK (NDs-BAK), in the second with 2 mL of 5% sodium hypochlorite (NaOCl) and in the last with 2 mL of 2% chlorhexidine (CHX). Specimens were rinsed and vertically fractured. Confocal laser scanning microscopy (CLSM) and viability staining were used to analyze the proportions of dead and live bacteria quantitat...

Quintessence International, 2011

This in vitro study investigated the depth of cure of a microhybrid composite resin when cured wi... more This in vitro study investigated the depth of cure of a microhybrid composite resin when cured with reduced times of exposure to three commercially available curing lights. Different sample thicknesses (1, 2, and 3 mm) were light cured in high intensity polymerization mode (2,400 mW/cm² for 5, 10, 15, and 20 seconds; 1,100 mW/cm² for 10, 20, 30, and 40 seconds; and 1,100 mW/cm² for 10, 20, 30, and 40 seconds, respectively). The degree of conversion (%) at the bottom of each sample was measured by Attenuated Total Reflection Fourier Transform Infrared (ATR F-TIR) analysis after each polymerization step. Data were analyzed by ANOVA for repeated measures, showing the degree of conversion was not influenced by the curing light employed (P = .622) but was significantly influenced by the thickness of composite resin (P < .05). Variations in the degree of conversion vs the shorter irradiation time permitted (T1) were not significant among different lamps but were significant among diffe...

This study evaluated the variation of conversion degree (DC) in the 12 hours following initial ph... more This study evaluated the variation of conversion degree (DC) in the 12 hours following initial photoactivation of a low-shrinkage composite resin (Venus Diamond). Material and Methods: The conversion degree was monitored for 12 hours using Attenuated 7RWDO 5HÀHFWLRQ $75

Four landmarks were placed in each block. Each specimen was mounted on a stable Basic Research–Te... more Four landmarks were placed in each block. Each specimen was mounted on a stable Basic Research–Technologysupport consisting of a rectangular slot of the size of the specimen (30 10 mm) and a support for a digital camera (Nikon D70, Tokyo, Japan), positioned centrally and at 90 degrees to the specimen. Digital images of all specimens before instrumen-tation were obtained and saved as TIFF format files. Specimens were then randomly as-signed to 4 different groups (n = 25) by using a random numbers table. In group 1 (mechanical preflaring–expert clinician), a #10 stainless steel K-file (Dentsply Maillefer) scouted the canal up to working length. Mechanical preflaring with new PathFile Rotary instruments 1, 2, and 3 at working length was performed by an endodontist by using an endodontic engine (X-Smart; Dentsply Maillefer) with a 16:1 contra angle, at the suggested setting (300 rpm on display, 5 Ncm). In group 2 (manual preflaring–expert clinician), manual preflaring with new stainless...

Odontology

The shaping outcomes after instrumentation with rotary and reciprocating glide path and shaping s... more The shaping outcomes after instrumentation with rotary and reciprocating glide path and shaping systems were evaluated through micro-computed tomography (Micro-CT). Thirty extracted maxillary first molars were selected. Mesio-buccal canals were randomized into two groups (n = 15): rotary system ProGlider and ProTaper Next X1, X2 (PG-PTN) and reciprocating system WaveOne Gold Glider and WaveOne Gold Primary (WOGG-WOG). Specimens were micro-CT scanned before, after glide path and after shaping. Increase in canal volume and surface area, percentage of removed dentin from the inner curvature, centroid shift and canal geometry variation through ratio of diameter ratios (RDR) and ratio of cross-sectional areas (RA) were measured in the apical and coronal levels and at the point of maximum curvature. The number of pecking motions needed to reach the working length (WL) was recorded. One-way ANOVA and post hoc Turkey–Kramer tests were used (p

word count: 242 words Text word count: 6176 words Tables/Figures: 3 tables

Giornale Italiano di Endodonzia, 2005

NiTi instrument separation is a serious concern in endodontic therapy. The analysis of NiTi files... more NiTi instrument separation is a serious concern in endodontic therapy. The analysis of NiTi files after torsional fracture reveals that the majority of torsional separations occur in the last mm. of the files and in the files with lower taper and/ or diameter. Consequentely, the tip of the smaller files presents the higher risk of torsional fracture and should be protected using low torque motors, reducing axial pressure and avoiding the tip from engaging root dentin (“taper lock”). In contrast, flexural fractures occur after repeated subthreshold loads have led to metal fatigue. Numerous studies evaluated the causes of stress and separation of rotary NiTi files concluding that a significant reduction of rotary instrument separation could be obtained when use of rotary file was anticipated by an initial manual preflaring and glide path. A strong evidence supports the importance of manual preflaring and glide path to reduce the frequency of rotary file separation. The initial preflar...

PURPOSE To evaluate the influence of operator experience on adhesive technique and to assess the ... more PURPOSE To evaluate the influence of operator experience on adhesive technique and to assess the clinical performances of two different adhesive systems. METHODS 90 cervical lesions in 42 subjects, with a mean age of 52.4 years (range between 32-63) were selected. Lesions were divided into two groups according to operator experience (n = 42 restorations performed by a skilled operator, n = 48 restorations performed by five unexperienced operators) and further divided into two subgroups according to the adhesive system used: three-step etch-and-rinse (Optibond FL) or one step self-etch (G-Bond). Adhesives were applied according to manufacturers' instructions. Subjects underwent follow-up at 12, 24, and 36 months and restoration retention, enamel and dentin marginal integrity, marginal discoloration, caries occurrence, post-operative sensitivity, and preservation of tooth vitality were evaluated according to USPSH criteria. ANOVA test was performed to evaluate the influence of the...

Aim: Apical periodontitis (AP) is correlated with a higher risk of developing cardiovascular dise... more Aim: Apical periodontitis (AP) is correlated with a higher risk of developing cardiovascular disease (CVD). No data currently exist to suggest that endothelial dysfunction (ED) improves after endodontic treatment in patients who have AP, despite a link between chronic AP and ED. This study was designed to investigate the expression of early ED markers in young adults with chronic AP, before and after root canal treatment. Methodology: 41 subjects (20 controls and 21 patients with AP) were examined at enrolment. Patients with AP were also assessed 2 and 12 months after treatment. ENDO-PAT was used to measure endothelial flow reserve (EFR) and ELISAs were used to assess plasma levels of interleukin (IL)-1, IL-6 and TNF-alpha, vasoconstrictor ED endothelin (ET)-1, the circulating endothelial adhesion markers intercellular adhesion molecule-1 (ICAM)-1/ CD54 and soluble vascular cellular adhesion molecule- 1 (sVCAM)-1/CD106, soluble CD14, and the endothelial leukocyte adhesion molecule E...

Applied Sciences

Recently, pre-mixed bioceramics in fast set formulations have been increasingly utilized in clini... more Recently, pre-mixed bioceramics in fast set formulations have been increasingly utilized in clinical practice as an alternative to mineral trioxide aggregate (MTA) for their shorter setting time and better handling properties. However, the impact on their osteogenic potential, due to modifications in chemical composition to promote a fast setting, is still unclear. This molecular and in vitro study compared the osteogenic potential of root repairing material putty fast set (FSP) with root-repairing material putty (RRMPU), root-repairing material paste (RRMPA), Biodentine™ and MTA. The null hypothesis tested was that there are no differences among the tricalcium silicate materials in terms of osteogenic potential. Standardized discs were cultured with MG-63 human osteoblastic-like cells to assess biocompatibility, the activity of alkaline phosphatase (ALP) and osteogenic potential. Biocompatibility was evaluated at baseline and after 24 and 48 h. Osteogenic differentiation was assess...

Journal of Clinical Medicine

This meta-analysis aimed to evaluate postoperative pain (POP) following root canal filling (RCF) ... more This meta-analysis aimed to evaluate postoperative pain (POP) following root canal filling (RCF) with gutta-percha/bioceramic sealer (BCS) vs. gutta-percha/traditional sealer (TS) techniques. Electronic databases were searched for randomized trials. Subgroup analyses were performed for analgesic intake, flare-ups, postoperative time (24/48 h), pulp status, and retreatment. The search yielded 682 records, and nine studies were selected. BCS was associated with significantly lower POP vs. TS at 24 h (P = 0.04) and 48 h (P = 0.0005). In addition, non-significant trends favoring BCS for analgesic intake at 24 h (P = 0.14), flare-ups (P = 0.24) and obturation techniques at 24 h (P = 0.41) and 48 h (P = 0.33), non-significant trends for lower POP with TS vs. BCS 24 h and 48 h in vital teeth (P = 0.50, P = 0.18, respectively), and for lower POP with BCS vs. TS in non-vital teeth at 24 h and 48 h (P = 0.16, P = 0.84, respectively). POP was numerically lower with TS vs. BCS at 24 h (P = 0.65...

Applied Sciences

Postoperative pain is a frequent complication of root canal treatment. It could worse patients’ q... more Postoperative pain is a frequent complication of root canal treatment. It could worse patients’ quality of life (QoL) and it may be associated to several factors, including the shaping technique. The aim of the study was to compare the impact of WaveOne Gold (WOG) and WaveOne Classic (WOC) reciprocating instrumentation on postoperative QoL after single-visit primary root canal treatment. Healthy subjects with pulp necrosis on multirooted teeth were observed. Canal shaping was performed with WaveOne Gold Primary (n = 25) or WaveOne Classic Primary (n = 29) and canal filling was completed with a carrier-based technique. Mean and maximum scores for postoperative pain were assessed through a Visual Analogue Scale (VAS) and QoL indicators were evaluated with a self-assessment questionnaire based on a Likert scale. Postoperative pain curves were similar in both groups (mean pain p = 0.43; maximum pain p = 0.27) and quality of life indicators showed no significant differences (p > 0.05)...

Applied Sciences

The present paper evaluated the accuracy of two different methods for transferring working length... more The present paper evaluated the accuracy of two different methods for transferring working length (WL) between manual endodontic instruments and nickel–titanium (NiTi) shaping files. Thirty root canals of extracted permanent teeth were used. Root canals were divided according to canal length (CL) and canal curvature (CC). The reference cusp and the root end were flattened to provide reproducible and accurate measurements. During shaping, the WL measurements were obtained with manual k-files (KF) and transferred to WaveOne (W1) NiTi reciprocating files using the traditional method with the endodontic ruler (method I) and an alternative clinical procedure based on the comparison of the instruments side by side from tip to shank (method II). For each file and each tested method, two measures were taken by two examiners using Rhino (ver. 4.0, McNeel, Seattle, WA, USA) software for a total of 360 (30 × 3 × 2 × 2) measures. Analysis of variance was performed by taking the difference in le...

Journal of Clinical Medicine, Aug 8, 2022

Applied Sciences

Background: The labial frenulum may be associated with traction on the marginal gingiva of the in... more Background: The labial frenulum may be associated with traction on the marginal gingiva of the incisors with resulting gingival recession, a condition known as “pull syndrome”. In this case, performing a frenulectomy at least 6 months before root covering surgery is necessary. Recently, tissue adhesives have been studied as a good alternative to conventional sutures. Methods: A 34-year-old female affected by pull syndrome of the central lower incisors underwent frenulectomy, and an n-hexyl-cyanoacrylate tissue adhesive was used to ensure wound closure. Results: The patient was instructed in hygiene maneuvers and rinsed with 0.12% chlorhexidine-based mouthwash for 15 days. The glue was partially removed at 7 days, and for the remaining, natural disposal time was expected. The wound healing process was complete after 15 days with minimal postoperative discomfort. Conclusion: This n-hexyl-cyanoacrylate surgical glue could be proposed as a viable alternative to conventional sutures duri...

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology, 2008

The purpose of this study was to evaluate the amounts of debris and smear layer remaining on cana... more The purpose of this study was to evaluate the amounts of debris and smear layer remaining on canal walls after preparation with ProTaper and Hero Shaper instruments in combination with NaOCl and EDTA irrigation in curved root canals. Study design. A total of 55 root canals were randomly divided into 2 instrumentation groups of 20 canals each and 1 negative control group of 15 canals. The canals in each of the 2 instrumentation groups were prepared with ProTaper or Hero Shaper instruments. Irrigation was performed with 5% NaOCl and 17% EDTA solutions. The control group was not instrumented. The remaining debris and smear layer were evaluated from scanning electron photomicrographs at ϫ200 and ϫ1,000 magnification taken in the coronal, middle, and apical thirds of the canals at both inner and outer canal walls. A 5-category scoring system for debris and smear layer was used. Statistical analysis was carried out using the Kruskal-Wallis and Mann-Whitney rank sum tests. Results. Completely clean root canals were not found in either instrumentation group. In the coronal and middle thirds, the canal walls of both instrumentation groups were clean, with no or only small areas of debris and smear layer. In the apical region, there were higher scores in terms of debris and smear layer in both instrumentation groups. No significant difference was found at the inner wall of the 2 instrumentation groups in terms of debris mean score. However, the outer canal walls prepared with ProTaper showed lower debris score compared with those prepared with Hero Shaper (P Ͻ 0.001). Concerning the smear layer, both the inner and outer canal walls prepared with ProTaper showed lower mean scores compared with those prepared with Hero Shaper (P Ͻ 0.001). Conclusions. Within the limitations of this study, both instruments in combination with NaOCl and EDTA irrigation produced a clean and debris-free canal surface in the coronal and middle thirds, but were unable to produce a canal surface free from debris and smear layer in the apical third. However, the canals prepared with ProTaper instruments showed smaller amounts of debris and smear layer remaining in the apical region. (Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2008;106:e63-e71)

Journal of Clinical Medicine

The aim was to evaluate the antibacterial efficacy and penetration depth into dentinal tubules of... more The aim was to evaluate the antibacterial efficacy and penetration depth into dentinal tubules of a solution of chitosan nanodroplets (NDs) loaded with Benzalkonium Chloride (BAK). Seventy-two human single-root teeth with fully formed apex were used. Cylindrical root dentin blocks were longitudinally sectioned and enlarged to a size of a Gates Glidden drill #4. After sterilization, root canals were infected with Enterococcus faecalis ATCC 29212 and further incubated for three weeks. Specimens were assigned to three experimental groups (n = 20), plus positive (n = 6) and negative (n = 6) controls. In the first group, irrigation was achieved with 2 mL of NDs solution loaded with BAK (NDs-BAK), in the second with 2 mL of 5% sodium hypochlorite (NaOCl) and in the last with 2 mL of 2% chlorhexidine (CHX). Specimens were rinsed and vertically fractured. Confocal laser scanning microscopy (CLSM) and viability staining were used to analyze the proportions of dead and live bacteria quantitat...

Quintessence International, 2011

This in vitro study investigated the depth of cure of a microhybrid composite resin when cured wi... more This in vitro study investigated the depth of cure of a microhybrid composite resin when cured with reduced times of exposure to three commercially available curing lights. Different sample thicknesses (1, 2, and 3 mm) were light cured in high intensity polymerization mode (2,400 mW/cm² for 5, 10, 15, and 20 seconds; 1,100 mW/cm² for 10, 20, 30, and 40 seconds; and 1,100 mW/cm² for 10, 20, 30, and 40 seconds, respectively). The degree of conversion (%) at the bottom of each sample was measured by Attenuated Total Reflection Fourier Transform Infrared (ATR F-TIR) analysis after each polymerization step. Data were analyzed by ANOVA for repeated measures, showing the degree of conversion was not influenced by the curing light employed (P = .622) but was significantly influenced by the thickness of composite resin (P < .05). Variations in the degree of conversion vs the shorter irradiation time permitted (T1) were not significant among different lamps but were significant among diffe...

This study evaluated the variation of conversion degree (DC) in the 12 hours following initial ph... more This study evaluated the variation of conversion degree (DC) in the 12 hours following initial photoactivation of a low-shrinkage composite resin (Venus Diamond). Material and Methods: The conversion degree was monitored for 12 hours using Attenuated 7RWDO 5HÀHFWLRQ $75

Four landmarks were placed in each block. Each specimen was mounted on a stable Basic Research–Te... more Four landmarks were placed in each block. Each specimen was mounted on a stable Basic Research–Technologysupport consisting of a rectangular slot of the size of the specimen (30 10 mm) and a support for a digital camera (Nikon D70, Tokyo, Japan), positioned centrally and at 90 degrees to the specimen. Digital images of all specimens before instrumen-tation were obtained and saved as TIFF format files. Specimens were then randomly as-signed to 4 different groups (n = 25) by using a random numbers table. In group 1 (mechanical preflaring–expert clinician), a #10 stainless steel K-file (Dentsply Maillefer) scouted the canal up to working length. Mechanical preflaring with new PathFile Rotary instruments 1, 2, and 3 at working length was performed by an endodontist by using an endodontic engine (X-Smart; Dentsply Maillefer) with a 16:1 contra angle, at the suggested setting (300 rpm on display, 5 Ncm). In group 2 (manual preflaring–expert clinician), manual preflaring with new stainless...

Odontology

The shaping outcomes after instrumentation with rotary and reciprocating glide path and shaping s... more The shaping outcomes after instrumentation with rotary and reciprocating glide path and shaping systems were evaluated through micro-computed tomography (Micro-CT). Thirty extracted maxillary first molars were selected. Mesio-buccal canals were randomized into two groups (n = 15): rotary system ProGlider and ProTaper Next X1, X2 (PG-PTN) and reciprocating system WaveOne Gold Glider and WaveOne Gold Primary (WOGG-WOG). Specimens were micro-CT scanned before, after glide path and after shaping. Increase in canal volume and surface area, percentage of removed dentin from the inner curvature, centroid shift and canal geometry variation through ratio of diameter ratios (RDR) and ratio of cross-sectional areas (RA) were measured in the apical and coronal levels and at the point of maximum curvature. The number of pecking motions needed to reach the working length (WL) was recorded. One-way ANOVA and post hoc Turkey–Kramer tests were used (p

word count: 242 words Text word count: 6176 words Tables/Figures: 3 tables

Giornale Italiano di Endodonzia, 2005

NiTi instrument separation is a serious concern in endodontic therapy. The analysis of NiTi files... more NiTi instrument separation is a serious concern in endodontic therapy. The analysis of NiTi files after torsional fracture reveals that the majority of torsional separations occur in the last mm. of the files and in the files with lower taper and/ or diameter. Consequentely, the tip of the smaller files presents the higher risk of torsional fracture and should be protected using low torque motors, reducing axial pressure and avoiding the tip from engaging root dentin (“taper lock”). In contrast, flexural fractures occur after repeated subthreshold loads have led to metal fatigue. Numerous studies evaluated the causes of stress and separation of rotary NiTi files concluding that a significant reduction of rotary instrument separation could be obtained when use of rotary file was anticipated by an initial manual preflaring and glide path. A strong evidence supports the importance of manual preflaring and glide path to reduce the frequency of rotary file separation. The initial preflar...

PURPOSE To evaluate the influence of operator experience on adhesive technique and to assess the ... more PURPOSE To evaluate the influence of operator experience on adhesive technique and to assess the clinical performances of two different adhesive systems. METHODS 90 cervical lesions in 42 subjects, with a mean age of 52.4 years (range between 32-63) were selected. Lesions were divided into two groups according to operator experience (n = 42 restorations performed by a skilled operator, n = 48 restorations performed by five unexperienced operators) and further divided into two subgroups according to the adhesive system used: three-step etch-and-rinse (Optibond FL) or one step self-etch (G-Bond). Adhesives were applied according to manufacturers' instructions. Subjects underwent follow-up at 12, 24, and 36 months and restoration retention, enamel and dentin marginal integrity, marginal discoloration, caries occurrence, post-operative sensitivity, and preservation of tooth vitality were evaluated according to USPSH criteria. ANOVA test was performed to evaluate the influence of the...

Aim: Apical periodontitis (AP) is correlated with a higher risk of developing cardiovascular dise... more Aim: Apical periodontitis (AP) is correlated with a higher risk of developing cardiovascular disease (CVD). No data currently exist to suggest that endothelial dysfunction (ED) improves after endodontic treatment in patients who have AP, despite a link between chronic AP and ED. This study was designed to investigate the expression of early ED markers in young adults with chronic AP, before and after root canal treatment. Methodology: 41 subjects (20 controls and 21 patients with AP) were examined at enrolment. Patients with AP were also assessed 2 and 12 months after treatment. ENDO-PAT was used to measure endothelial flow reserve (EFR) and ELISAs were used to assess plasma levels of interleukin (IL)-1, IL-6 and TNF-alpha, vasoconstrictor ED endothelin (ET)-1, the circulating endothelial adhesion markers intercellular adhesion molecule-1 (ICAM)-1/ CD54 and soluble vascular cellular adhesion molecule- 1 (sVCAM)-1/CD106, soluble CD14, and the endothelial leukocyte adhesion molecule E...

Applied Sciences

Recently, pre-mixed bioceramics in fast set formulations have been increasingly utilized in clini... more Recently, pre-mixed bioceramics in fast set formulations have been increasingly utilized in clinical practice as an alternative to mineral trioxide aggregate (MTA) for their shorter setting time and better handling properties. However, the impact on their osteogenic potential, due to modifications in chemical composition to promote a fast setting, is still unclear. This molecular and in vitro study compared the osteogenic potential of root repairing material putty fast set (FSP) with root-repairing material putty (RRMPU), root-repairing material paste (RRMPA), Biodentine™ and MTA. The null hypothesis tested was that there are no differences among the tricalcium silicate materials in terms of osteogenic potential. Standardized discs were cultured with MG-63 human osteoblastic-like cells to assess biocompatibility, the activity of alkaline phosphatase (ALP) and osteogenic potential. Biocompatibility was evaluated at baseline and after 24 and 48 h. Osteogenic differentiation was assess...

Journal of Clinical Medicine

This meta-analysis aimed to evaluate postoperative pain (POP) following root canal filling (RCF) ... more This meta-analysis aimed to evaluate postoperative pain (POP) following root canal filling (RCF) with gutta-percha/bioceramic sealer (BCS) vs. gutta-percha/traditional sealer (TS) techniques. Electronic databases were searched for randomized trials. Subgroup analyses were performed for analgesic intake, flare-ups, postoperative time (24/48 h), pulp status, and retreatment. The search yielded 682 records, and nine studies were selected. BCS was associated with significantly lower POP vs. TS at 24 h (P = 0.04) and 48 h (P = 0.0005). In addition, non-significant trends favoring BCS for analgesic intake at 24 h (P = 0.14), flare-ups (P = 0.24) and obturation techniques at 24 h (P = 0.41) and 48 h (P = 0.33), non-significant trends for lower POP with TS vs. BCS 24 h and 48 h in vital teeth (P = 0.50, P = 0.18, respectively), and for lower POP with BCS vs. TS in non-vital teeth at 24 h and 48 h (P = 0.16, P = 0.84, respectively). POP was numerically lower with TS vs. BCS at 24 h (P = 0.65...

Applied Sciences

Postoperative pain is a frequent complication of root canal treatment. It could worse patients’ q... more Postoperative pain is a frequent complication of root canal treatment. It could worse patients’ quality of life (QoL) and it may be associated to several factors, including the shaping technique. The aim of the study was to compare the impact of WaveOne Gold (WOG) and WaveOne Classic (WOC) reciprocating instrumentation on postoperative QoL after single-visit primary root canal treatment. Healthy subjects with pulp necrosis on multirooted teeth were observed. Canal shaping was performed with WaveOne Gold Primary (n = 25) or WaveOne Classic Primary (n = 29) and canal filling was completed with a carrier-based technique. Mean and maximum scores for postoperative pain were assessed through a Visual Analogue Scale (VAS) and QoL indicators were evaluated with a self-assessment questionnaire based on a Likert scale. Postoperative pain curves were similar in both groups (mean pain p = 0.43; maximum pain p = 0.27) and quality of life indicators showed no significant differences (p > 0.05)...

Applied Sciences

The present paper evaluated the accuracy of two different methods for transferring working length... more The present paper evaluated the accuracy of two different methods for transferring working length (WL) between manual endodontic instruments and nickel–titanium (NiTi) shaping files. Thirty root canals of extracted permanent teeth were used. Root canals were divided according to canal length (CL) and canal curvature (CC). The reference cusp and the root end were flattened to provide reproducible and accurate measurements. During shaping, the WL measurements were obtained with manual k-files (KF) and transferred to WaveOne (W1) NiTi reciprocating files using the traditional method with the endodontic ruler (method I) and an alternative clinical procedure based on the comparison of the instruments side by side from tip to shank (method II). For each file and each tested method, two measures were taken by two examiners using Rhino (ver. 4.0, McNeel, Seattle, WA, USA) software for a total of 360 (30 × 3 × 2 × 2) measures. Analysis of variance was performed by taking the difference in le...