Elishai Ezra - Academia.edu (original) (raw)
Related Authors
Graduate Center of the City University of New York
Uploads
Papers by Elishai Ezra
2021 IEEE Biomedical Circuits and Systems Conference (BioCAS)
2021 IEEE Biomedical Circuits and Systems Conference (BioCAS)
2021 IEEE Biomedical Circuits and Systems Conference (BioCAS)
Neuromorphic Engineering, 2021
Neuromorphic Engineering, 2021
Neuromorphic Engineering, 2021
Neuromorphic Engineering, 2021
Neuromorphic Engineering, 2021
Neuromorphic Engineering, 2021
Neuromorphic Engineering, 2021
bioRxiv, 2021
Retinal direction-selectivity originates in starburst amacrine cells (SACs), which display a cent... more Retinal direction-selectivity originates in starburst amacrine cells (SACs), which display a centrifugal preference, responding with greater depolarization to a stimulus expanding from soma to dendrites than to a collapsing stimulus. Various mechanisms were hypothesized to underlie SAC centrifugal preference, but dissociating them is experimentally challenging and the mechanisms remain debatable. To address this issue, we developed the Retinal Stimulation Modeling Environment (RSME), a multifaceted data-driven retinal model that encompasses detailed neuronal morphology and biophysical properties, retina-tailored connectivity scheme and visual input. Using a genetic algorithm, we demonstrated that spatiotemporally diverse excitatory inputs – sustained in the proximal and transient in the distal processes – are sufficient to generate experimentally validated centrifugal preference in a single SAC. Reversing these input kinetics did not produce any centrifugal-preferring SAC. We then e...
Recent findings suggest that electroencephalography (EEG) oscillations in the theta and alpha fre... more Recent findings suggest that electroencephalography (EEG) oscillations in the theta and alpha frequency-bands reflect synchronized interregional neuronal activity and are considered to reflect cognitive-control, and executive working memory mechanisms in humans. Above the age of 50 years, hypothesized pronounced alterations in alpha and theta-band power at resting or across different WM-functioning brain states may well be due to pre-dementia cognitive impairments, or increasing severity of age-related neurological disorders. Executive working memory (EWM) functioning was assessed in older-adult participants (54 to 83 years old) by obtaining their WM-related EEG oscillations and WM performance scores. WM performance and WM brain-state EEG were recorded during online-WM periods as well as during specific online WM events within EWM periods, and during resting offline-WM periods that preceded online-WM periods. Left-prefrontal alpha-power was enhanced during offline-WM periods versus ...
2021 IEEE Biomedical Circuits and Systems Conference (BioCAS)
2021 IEEE Biomedical Circuits and Systems Conference (BioCAS)
2021 IEEE Biomedical Circuits and Systems Conference (BioCAS)
Neuromorphic Engineering, 2021
Neuromorphic Engineering, 2021
Neuromorphic Engineering, 2021
Neuromorphic Engineering, 2021
Neuromorphic Engineering, 2021
Neuromorphic Engineering, 2021
Neuromorphic Engineering, 2021
bioRxiv, 2021
Retinal direction-selectivity originates in starburst amacrine cells (SACs), which display a cent... more Retinal direction-selectivity originates in starburst amacrine cells (SACs), which display a centrifugal preference, responding with greater depolarization to a stimulus expanding from soma to dendrites than to a collapsing stimulus. Various mechanisms were hypothesized to underlie SAC centrifugal preference, but dissociating them is experimentally challenging and the mechanisms remain debatable. To address this issue, we developed the Retinal Stimulation Modeling Environment (RSME), a multifaceted data-driven retinal model that encompasses detailed neuronal morphology and biophysical properties, retina-tailored connectivity scheme and visual input. Using a genetic algorithm, we demonstrated that spatiotemporally diverse excitatory inputs – sustained in the proximal and transient in the distal processes – are sufficient to generate experimentally validated centrifugal preference in a single SAC. Reversing these input kinetics did not produce any centrifugal-preferring SAC. We then e...
Recent findings suggest that electroencephalography (EEG) oscillations in the theta and alpha fre... more Recent findings suggest that electroencephalography (EEG) oscillations in the theta and alpha frequency-bands reflect synchronized interregional neuronal activity and are considered to reflect cognitive-control, and executive working memory mechanisms in humans. Above the age of 50 years, hypothesized pronounced alterations in alpha and theta-band power at resting or across different WM-functioning brain states may well be due to pre-dementia cognitive impairments, or increasing severity of age-related neurological disorders. Executive working memory (EWM) functioning was assessed in older-adult participants (54 to 83 years old) by obtaining their WM-related EEG oscillations and WM performance scores. WM performance and WM brain-state EEG were recorded during online-WM periods as well as during specific online WM events within EWM periods, and during resting offline-WM periods that preceded online-WM periods. Left-prefrontal alpha-power was enhanced during offline-WM periods versus ...