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Papers by Elizabeth Sanchez
Cimel Ciencia E Investigacion Medica Estudiantil Latinoamericana, 2009
Amer Psychol, 2003
Beginning with the HMO Act of 1973, managed care, a system for controlling health care costs, rap... more Beginning with the HMO Act of 1973, managed care, a system for controlling health care costs, rapidly expanded and gained influence as the main vehicle for health care delivery in the United States. Implementation of managed care principles in the mental health arena has generated much debate, particularly with respect to issues of quality of care. The authors briefly trace the development of managed care and evaluate its impact on the practice of psychology. The extant literature is reviewed with specific attention to issues of quality of care, confidentiality of patient information, and shifting practice patterns of clinicians. Finally, the future of professional psychology within the context of managed care is examined, and the implications of newly created mental health roles for practitioners, training programs, and organized psychology are discussed.
Revista Peruana De Medicina Experimental Y Salud Publica, Jun 1, 2014
Antigenic fractions of 27-28 kDa from Fasciola hepatica were purified by size-exclusion chromatog... more Antigenic fractions of 27-28 kDa from Fasciola hepatica were purified by size-exclusion chromatography for use in the diagnosis of human fasciolosis. Excretion and secretion antigens were obtained from living adult flukes collected from sheep and cattle liver, and cultured in minimum essential medium. The reactivity of the purified antigen and efficacy were assessed by immunoblot test using four sera with human fascioliasis; four sera with other parasites, and two negative sera. We conclude that the purified antigenic fractions do not cross-react with other parasites by immunoblot. Therefore, purified proteins are considered as potential candidates to be used for the diagnosis of human fascioliasis.
Evid Based Complement Altern, 2010
This article presents the hypothesis that acupuncture enhances anticancer immune functions by sti... more This article presents the hypothesis that acupuncture enhances anticancer immune functions by stimulating natural killer (NK) cells. It provides background information on acupuncture, summarizes the current scientific understanding of the mechanisms through which NK cells act to eliminate cancer cells, and reviews evidence that acupuncture is associated with increases in NK cell quantity and function in both animals and humans. The key contribution of this article involves the use of cellular immunology and molecular biological theory to interpret and synthesize evidence from disparate animal and human studies in formulating the 'acupuncture immuno-enhancement hypothesis': clinicians may use acupuncture to promote the induction and secretion of NK-cell activating cytokines that engage specific NK cell receptors that endogenously enhance anticancer immune function.
Pharmacoeconomics, 2000
The serotonin 5-HT3 receptor antagonists or `setrons&... more The serotonin 5-HT3 receptor antagonists or `setrons' have become the standard of care for the prevention of chemotherapy-induced emesis (CIE) and are first-line therapy for acute CIE in healthcare organisations worldwide. However, their superior efficacy versus standard antiemetics comes at a significant cost. Currently, 3 agents are available in the US: ondansetron, granisetron and dolasetron. The most important treatment-related factor
Revista Peruana De Medicina Experimental Y Salud Publica, 2014
Perspectives in Vascular Surgery and Endovascular Therapy, 1998
ABSTRACT
J Pers Disord, 2003
Clinical approaches in treating and preventing suicidal behaviors in patients with borderline per... more Clinical approaches in treating and preventing suicidal behaviors in patients with borderline personality disorder (BPD) have received limited attention. To stimulate further work in this area, we present a behavioral activation treatment for depression (BATD; that has shown promising results in treating clinically depressed patients and a theoretical conceptualization for why BATD may prove particularly useful in reducing the frequency of suicide-related behaviors and other symptoms characteristic of patients with BPD. We also present theoretical consistencies between BATD and the well-established intervention of dialectical behavior therapy (DBT; Linehan, 1993), which may allow for their practical integration, and conclude with a case study that illustrates the assimilation of these strategies in the treatment of a patient with BPD.
Avances En Enfermeria, Dec 1, 2007
Perspectives in Vascular Surgery and Endovascular Therapy, 1994
Scientific Reports, 2016
Adipsin is a protease produced at high levels by adipose tissue. It is involved in complement act... more Adipsin is a protease produced at high levels by adipose tissue. It is involved in complement activation and metabolic control. The objective of this study was to determine the changes in adipsin levels during different stages of normal pregnancy, and its association with obstetric outcomes, such as preeclampsia. This nested case-control study in a longitudinal cohort included normal pregnant (n = 54) and preeclamptic (n = 18) women, both followed throughout pregnancy. Additionally, some of the normal pregnant women were followed up three months postpartum (n = 18). Healthy non-pregnant women were also studied during their menstrual cycle (n = 20). The results of this study show that in healthy non-pregnant women, adipsin levels did not change significantly during the menstrual cycle. In normal pregnant women, adipsin levels were lower (p < 0.01) when compared with non-pregnant healthy women, but these serum levels increased again during postpartum (p < 0.001). Adipsin levels were significantly elevated in preeclamptic women in late pregnancy (P < 0.01). A significant correlation was not found between leptin and adipsin during the three periods of gestation studied in healthy pregnant and preeclamptic women. Our results suggest that adipsin may be involved in pregnancyassociated metabolic changes. Moreover, the increase of adipsin levels towards late gestation in preeclamptic women could be related to the pathophysiology of this disease.
Revista Facultad De Odontologia Universidad De Antioquia, Jun 1, 2015
Revista Peruana De Medicina Experimental Y Salud Publica, Apr 1, 2009
Revista Facultad De Odontologia Universidad De Antioquia, Apr 20, 2015
Introducción: los pocos estudios hechos con radiografía cefálica lateral digital en niños menores... more Introducción: los pocos estudios hechos con radiografía cefálica lateral digital en niños menores de 6 años, hace necesario investigar en dicho grupo etario. El propósito del presente estudio fue determinar las medidas cefalométricas promedio en niños de 3 a 6 años con oclusión dental clase I, residentes en el municipio de Medellín, estimando diferencias por edad, sexo, biotipo facial, peso y talla. Métodos: se hizo un estudio descriptivo de corte transversal, en donde se tomó una radiografía cefálica lateral digital, a 99 niños de 3 a 6 años que cumplieron los criterios de inclusión para determinar promedios cefalométricos. Resultados: entre 3 y 4 años existe mayor dimorfismo sexual, presentando las niñas maxilar y mandíbula más protrusivos, estas diferencias son menores a los 5 años, llegando a ser imperceptibles a los 6. El comportamiento de las variables por edad evidencia que las medidas longitudinales tienden a aumentar con la edad. Los niños dólico presentaron valores mayores en las medidas lineales en sentido anteroposterior, mientras que los lepto mostraron valores mayores en las medidas angulares en sentido vertical. No hubo diferencias estadísticamente significativas en la relación peso y talla con las variables cefalométricas. Conclusiones: el valor de las medidas lineales aumenta a medida que aumenta la edad, lo que justifica el uso de estándares específicos para cada edad. Esta investigación sugiere que existe dimorfismo sexual entre las variables cefalométricas, siendo más evidente a los 3 y 4 años. Los diferentes biotipos faciales exhiben características cefalométricas específicas.
Revista Mexicana De Ciencias Farmaceuticas, 2010
Vascular and Endovascular Surgery
ABSTRACT
Monitoring tissue oxygenation (StO(2)) by visible light spectroscopy (VLS) can identify tissue is... more Monitoring tissue oxygenation (StO(2)) by visible light spectroscopy (VLS) can identify tissue ischemia, but its feasibility for detecting myocardial ischemia is not known. We hypothesized that VLS can reliably detect changes in myocardial StO(2) in pigs subjected to acute regional or global myocardial ischemia. In 11 pigs, regional myocardial ischemia was created by ligation of left anterior descending artery (LAD). Myocardial StO(2) was determined from the ischemic and nonischemic left ventricular (LV) regions and compared to coronary venous saturations. Myocardial function was assessed by echocardiography. In six pigs, LV-StO(2) was measured during cardiopulmonary bypass (CPB), after cardioplegic cardiac arrest, and during CPB with inadequate myocardial protection. Additionally, right ventricular (RV)- and LV-StO(2) were assessed during acute RV pressure overload from pulmonary artery (PA) banding. StO(2) baselines in pigs undergoing LAD occlusion were similar in the ischemic and nonischemic myocardium (70% +/- 8% vs 74% +/- 5%). After LAD ligation, StO(2) rapidly declined (30 s: 59% +/- 8%; 1 min:50 +/- 9; 5 min:42% +/- 4%; P &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.05) in the ischemic myocardium. Decreases in StO(2) correlated with coronary venous saturations (r = 0.88) and were associated with myocardial dysfunction. In pigs undergoing CPB, LV-StO(2) remained unchanged with initiation of CPB or after cardioplegic cardiac arrest, but LV ischemia was detected by StO(2) after aortic cross-clamp without adequate myocardial protection. Similarly, PA banding resulted in a profound decrease of RV-StO(2) from 69% +/- 6% to 52% +/- 7% (P &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.05) with recovery after PA release. VLS is a reliable method of detecting alterations in myocardial StO(2) and can be a useful monitor for rapid identification of myocardial ischemia.
Cimel Ciencia E Investigacion Medica Estudiantil Latinoamericana, 2009
Amer Psychol, 2003
Beginning with the HMO Act of 1973, managed care, a system for controlling health care costs, rap... more Beginning with the HMO Act of 1973, managed care, a system for controlling health care costs, rapidly expanded and gained influence as the main vehicle for health care delivery in the United States. Implementation of managed care principles in the mental health arena has generated much debate, particularly with respect to issues of quality of care. The authors briefly trace the development of managed care and evaluate its impact on the practice of psychology. The extant literature is reviewed with specific attention to issues of quality of care, confidentiality of patient information, and shifting practice patterns of clinicians. Finally, the future of professional psychology within the context of managed care is examined, and the implications of newly created mental health roles for practitioners, training programs, and organized psychology are discussed.
Revista Peruana De Medicina Experimental Y Salud Publica, Jun 1, 2014
Antigenic fractions of 27-28 kDa from Fasciola hepatica were purified by size-exclusion chromatog... more Antigenic fractions of 27-28 kDa from Fasciola hepatica were purified by size-exclusion chromatography for use in the diagnosis of human fasciolosis. Excretion and secretion antigens were obtained from living adult flukes collected from sheep and cattle liver, and cultured in minimum essential medium. The reactivity of the purified antigen and efficacy were assessed by immunoblot test using four sera with human fascioliasis; four sera with other parasites, and two negative sera. We conclude that the purified antigenic fractions do not cross-react with other parasites by immunoblot. Therefore, purified proteins are considered as potential candidates to be used for the diagnosis of human fascioliasis.
Evid Based Complement Altern, 2010
This article presents the hypothesis that acupuncture enhances anticancer immune functions by sti... more This article presents the hypothesis that acupuncture enhances anticancer immune functions by stimulating natural killer (NK) cells. It provides background information on acupuncture, summarizes the current scientific understanding of the mechanisms through which NK cells act to eliminate cancer cells, and reviews evidence that acupuncture is associated with increases in NK cell quantity and function in both animals and humans. The key contribution of this article involves the use of cellular immunology and molecular biological theory to interpret and synthesize evidence from disparate animal and human studies in formulating the 'acupuncture immuno-enhancement hypothesis': clinicians may use acupuncture to promote the induction and secretion of NK-cell activating cytokines that engage specific NK cell receptors that endogenously enhance anticancer immune function.
Pharmacoeconomics, 2000
The serotonin 5-HT3 receptor antagonists or `setrons&amp;amp;amp;amp;amp;amp;amp;amp;amp;... more The serotonin 5-HT3 receptor antagonists or `setrons&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;#39; have become the standard of care for the prevention of chemotherapy-induced emesis (CIE) and are first-line therapy for acute CIE in healthcare organisations worldwide. However, their superior efficacy versus standard antiemetics comes at a significant cost. Currently, 3 agents are available in the US: ondansetron, granisetron and dolasetron. The most important treatment-related factor
Revista Peruana De Medicina Experimental Y Salud Publica, 2014
Perspectives in Vascular Surgery and Endovascular Therapy, 1998
ABSTRACT
J Pers Disord, 2003
Clinical approaches in treating and preventing suicidal behaviors in patients with borderline per... more Clinical approaches in treating and preventing suicidal behaviors in patients with borderline personality disorder (BPD) have received limited attention. To stimulate further work in this area, we present a behavioral activation treatment for depression (BATD; that has shown promising results in treating clinically depressed patients and a theoretical conceptualization for why BATD may prove particularly useful in reducing the frequency of suicide-related behaviors and other symptoms characteristic of patients with BPD. We also present theoretical consistencies between BATD and the well-established intervention of dialectical behavior therapy (DBT; Linehan, 1993), which may allow for their practical integration, and conclude with a case study that illustrates the assimilation of these strategies in the treatment of a patient with BPD.
Avances En Enfermeria, Dec 1, 2007
Perspectives in Vascular Surgery and Endovascular Therapy, 1994
Scientific Reports, 2016
Adipsin is a protease produced at high levels by adipose tissue. It is involved in complement act... more Adipsin is a protease produced at high levels by adipose tissue. It is involved in complement activation and metabolic control. The objective of this study was to determine the changes in adipsin levels during different stages of normal pregnancy, and its association with obstetric outcomes, such as preeclampsia. This nested case-control study in a longitudinal cohort included normal pregnant (n = 54) and preeclamptic (n = 18) women, both followed throughout pregnancy. Additionally, some of the normal pregnant women were followed up three months postpartum (n = 18). Healthy non-pregnant women were also studied during their menstrual cycle (n = 20). The results of this study show that in healthy non-pregnant women, adipsin levels did not change significantly during the menstrual cycle. In normal pregnant women, adipsin levels were lower (p < 0.01) when compared with non-pregnant healthy women, but these serum levels increased again during postpartum (p < 0.001). Adipsin levels were significantly elevated in preeclamptic women in late pregnancy (P < 0.01). A significant correlation was not found between leptin and adipsin during the three periods of gestation studied in healthy pregnant and preeclamptic women. Our results suggest that adipsin may be involved in pregnancyassociated metabolic changes. Moreover, the increase of adipsin levels towards late gestation in preeclamptic women could be related to the pathophysiology of this disease.
Revista Facultad De Odontologia Universidad De Antioquia, Jun 1, 2015
Revista Peruana De Medicina Experimental Y Salud Publica, Apr 1, 2009
Revista Facultad De Odontologia Universidad De Antioquia, Apr 20, 2015
Introducción: los pocos estudios hechos con radiografía cefálica lateral digital en niños menores... more Introducción: los pocos estudios hechos con radiografía cefálica lateral digital en niños menores de 6 años, hace necesario investigar en dicho grupo etario. El propósito del presente estudio fue determinar las medidas cefalométricas promedio en niños de 3 a 6 años con oclusión dental clase I, residentes en el municipio de Medellín, estimando diferencias por edad, sexo, biotipo facial, peso y talla. Métodos: se hizo un estudio descriptivo de corte transversal, en donde se tomó una radiografía cefálica lateral digital, a 99 niños de 3 a 6 años que cumplieron los criterios de inclusión para determinar promedios cefalométricos. Resultados: entre 3 y 4 años existe mayor dimorfismo sexual, presentando las niñas maxilar y mandíbula más protrusivos, estas diferencias son menores a los 5 años, llegando a ser imperceptibles a los 6. El comportamiento de las variables por edad evidencia que las medidas longitudinales tienden a aumentar con la edad. Los niños dólico presentaron valores mayores en las medidas lineales en sentido anteroposterior, mientras que los lepto mostraron valores mayores en las medidas angulares en sentido vertical. No hubo diferencias estadísticamente significativas en la relación peso y talla con las variables cefalométricas. Conclusiones: el valor de las medidas lineales aumenta a medida que aumenta la edad, lo que justifica el uso de estándares específicos para cada edad. Esta investigación sugiere que existe dimorfismo sexual entre las variables cefalométricas, siendo más evidente a los 3 y 4 años. Los diferentes biotipos faciales exhiben características cefalométricas específicas.
Revista Mexicana De Ciencias Farmaceuticas, 2010
Vascular and Endovascular Surgery
ABSTRACT
Monitoring tissue oxygenation (StO(2)) by visible light spectroscopy (VLS) can identify tissue is... more Monitoring tissue oxygenation (StO(2)) by visible light spectroscopy (VLS) can identify tissue ischemia, but its feasibility for detecting myocardial ischemia is not known. We hypothesized that VLS can reliably detect changes in myocardial StO(2) in pigs subjected to acute regional or global myocardial ischemia. In 11 pigs, regional myocardial ischemia was created by ligation of left anterior descending artery (LAD). Myocardial StO(2) was determined from the ischemic and nonischemic left ventricular (LV) regions and compared to coronary venous saturations. Myocardial function was assessed by echocardiography. In six pigs, LV-StO(2) was measured during cardiopulmonary bypass (CPB), after cardioplegic cardiac arrest, and during CPB with inadequate myocardial protection. Additionally, right ventricular (RV)- and LV-StO(2) were assessed during acute RV pressure overload from pulmonary artery (PA) banding. StO(2) baselines in pigs undergoing LAD occlusion were similar in the ischemic and nonischemic myocardium (70% +/- 8% vs 74% +/- 5%). After LAD ligation, StO(2) rapidly declined (30 s: 59% +/- 8%; 1 min:50 +/- 9; 5 min:42% +/- 4%; P &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.05) in the ischemic myocardium. Decreases in StO(2) correlated with coronary venous saturations (r = 0.88) and were associated with myocardial dysfunction. In pigs undergoing CPB, LV-StO(2) remained unchanged with initiation of CPB or after cardioplegic cardiac arrest, but LV ischemia was detected by StO(2) after aortic cross-clamp without adequate myocardial protection. Similarly, PA banding resulted in a profound decrease of RV-StO(2) from 69% +/- 6% to 52% +/- 7% (P &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.05) with recovery after PA release. VLS is a reliable method of detecting alterations in myocardial StO(2) and can be a useful monitor for rapid identification of myocardial ischemia.