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Papers by Engku Engku-Husna

Research paper thumbnail of A 10-Year Review of Obstetrics Anal Sphincter Injury at a Tertiary Teaching Hospital in the East Coast of Peninsular Malaysia

Journal of Clinical and Health Sciences

Introduction: Obstetric anal sphincter injury (OASIS) is an uncommon complication that may occur ... more Introduction: Obstetric anal sphincter injury (OASIS) is an uncommon complication that may occur during vaginal delivery and increases the risk of pelvic floor dysfunction following delivery. This 10-year review is aimed to determine the occurrence of OASIS at a tertiary teaching hospital. Methods: A retrospective review of records of women who had their newborns delivered at Hospital Universiti Sains Malaysia between 2007-2016 was conducted. OASIS was classified according to the classification proposed by Sultan AH in 1999. Women who delivered on the same day with the index delivery but without OASIS acted as the control group (n = 154). Results: There were 61,049 vaginal deliveries over the ten years. A total of 154 women were recorded to have vaginal delivery complicated with OASIS, with a cumulative prevalence of 0.25% per year. Of these, 86% (n = 133) sustained a third-degree, and the remaining 14% (n = 21) had a fourth-degree perineal tear. Three independent risk factors for O...

Research paper thumbnail of A 10-Year Review of Methotrexate Treatment for Ectopic Pregnancy in a Malaysian Tertiary Referral Hospital

Cureus, Oct 17, 2022

Background Ectopic pregnancy was recorded as the fourth principal cause of maternal death in Mala... more Background Ectopic pregnancy was recorded as the fourth principal cause of maternal death in Malaysia in 2019. Early diagnosis and use of methotrexate treatment proved to be safe and effective alternatives to surgical treatment. This study investigates the success rate of methotrexate treatment for ectopic pregnancy in a tertiary hospital in Malaysia. Methods This was a retrospective review of 73 patients with ectopic pregnancies treated with methotrexate according to a single-dose protocol from January 2009 until November 2019. The diagnosis of ectopic pregnancy was made using a combination of transvaginal scan and serial serum β-hCG levels. Their clinical and demographic data were reviewed. Serum β-hCG levels were measured at pre-and post-treatment to determine the rate of successful resolution. Results The overall success rate was 87.7% (64/73 patients) with methotrexate treatment. Fifty-six patients (76.7%) were successfully treated with a single dose of methotrexate, and eight patients (11.0%) required a second dose of methotrexate. There was no relation between socio-demographic, pre-treatment β-hCG levels, ectopic mass size, and treatment efficacy. Smaller size of ectopic pregnancy (adjusted OR=29.23; 95% CI: 2.69, 317.90; P=0.006) and absence of free fluid at the pouch of Douglas (POD) (adjusted OR=27.31; 95% CI: 2.84, 262.32; P=0.004) was found to increase the likelihood of overall treatment success. Absence of fetal cardiac activities was found to increase the likelihood of first-dose methotrexate treatment success (OR=10.20; 95% CI: 1.93, 53.79; P=0.006). Conclusions Early diagnosis of ectopic pregnancy may reduce morbidity and mortality. In carefully selected cases, methotrexate treatment has been proven to be cost-effective and avoided risks associated with surgery and anaesthesia.

Research paper thumbnail of A Review on Magnetic Induction Spectroscopy Potential for Fetal Acidosis Examination

Sensors, 2022

Fetal acidosis is one of the main concerns during labor. Currently, fetal blood sampling (FBS) ha... more Fetal acidosis is one of the main concerns during labor. Currently, fetal blood sampling (FBS) has become the most accurate measurement of acidosis detection. However, it is invasive and does not provide a real time measurement due to laboratory procedures. Delays in diagnosis of acidosis have caused serious injury to the fetus, especially for the brain and the heart. This paper reviews the new technique in diagnosis of acidosis non-invasively. Magnetic Induction Spectroscopy (MIS) has been proposed to be a new device for acidosis detection in recent years. This paper explains the basic principle of MIS and outlines the design specifications and design considerations for a MIS pH probe. It is expected that readers will gain a basic understanding of the development of a MIS pH probe from this review.

Research paper thumbnail of Placenta increta presenting with threatened miscarriage during the first trimester in rhesus-negative mother: a case report

Journal of Medical Case Reports, 2021

Placenta accreta is known to be associated with significant maternal morbidity and mortality—prim... more Placenta accreta is known to be associated with significant maternal morbidity and mortality—primarily due to intractable bleeding during abortion or delivery at any level of gestation. The complications could be reduced if placenta accreta is suspected in a patient with a history of previous cesarean delivery and the gestational sac/placenta is located at the lower part of the uterus. Then, a proper management plan can be instituted, and complications can be reduced. The diagnosis of placenta accreta in the first trimester of pregnancy is considered uncommon. A 34-year-old Malay, gravida 4, para 3, rhesus-negative woman was referred from a private hospital at 13 weeks owing to accreta suspicion for further management. She has a history of three previous lower-segment cesarean sections. She also had per vaginal bleeding in the early first trimester, which is considered to indicate threatened miscarriage. Transabdominal ultrasound revealed features consistent with placenta accreta sp...

Research paper thumbnail of Müllerian duct anomalies with term pregnancy: a case report

Journal of Medical Case Reports

Background Müllerian duct anomaly is a rare condition. Many cases remain unidentified, especially... more Background Müllerian duct anomaly is a rare condition. Many cases remain unidentified, especially if asymptomatic. Thus, it is difficult to determine the actual incidence. Müllerian duct anomaly is associated with a wide range of gynecological and obstetric complications, namely infertility, endometriosis, urinary tract anomalies, and preterm delivery. Furthermore, congenital anomalies in pregnant mothers have a high risk of being genetically transmitted to their offspring. Case presentation We report a case of a patient with unsuspected müllerian duct anomaly in a term pregnancy. A 33-year-old Malay woman with previously uninvestigated involuntary primary infertility for 4 years presented with acute right pyelonephritis in labor at 38 weeks of gestation. She has had multiple congenital anomalies since birth and had undergone numerous surgeries during childhood. Her range of congenital defects included hydrocephalus, for which she was put on a ventriculoperitoneal shunt; imperforate...

Research paper thumbnail of A 10-Year Review of Obstetrics Anal Sphincter Injury at a Tertiary Teaching Hospital in the East Coast of Peninsular Malaysia

Journal of Clinical and Health Sciences

Introduction: Obstetric anal sphincter injury (OASIS) is an uncommon complication that may occur ... more Introduction: Obstetric anal sphincter injury (OASIS) is an uncommon complication that may occur during vaginal delivery and increases the risk of pelvic floor dysfunction following delivery. This 10-year review is aimed to determine the occurrence of OASIS at a tertiary teaching hospital. Methods: A retrospective review of records of women who had their newborns delivered at Hospital Universiti Sains Malaysia between 2007-2016 was conducted. OASIS was classified according to the classification proposed by Sultan AH in 1999. Women who delivered on the same day with the index delivery but without OASIS acted as the control group (n = 154). Results: There were 61,049 vaginal deliveries over the ten years. A total of 154 women were recorded to have vaginal delivery complicated with OASIS, with a cumulative prevalence of 0.25% per year. Of these, 86% (n = 133) sustained a third-degree, and the remaining 14% (n = 21) had a fourth-degree perineal tear. Three independent risk factors for O...

Research paper thumbnail of A 10-Year Review of Methotrexate Treatment for Ectopic Pregnancy in a Malaysian Tertiary Referral Hospital

Cureus, Oct 17, 2022

Background Ectopic pregnancy was recorded as the fourth principal cause of maternal death in Mala... more Background Ectopic pregnancy was recorded as the fourth principal cause of maternal death in Malaysia in 2019. Early diagnosis and use of methotrexate treatment proved to be safe and effective alternatives to surgical treatment. This study investigates the success rate of methotrexate treatment for ectopic pregnancy in a tertiary hospital in Malaysia. Methods This was a retrospective review of 73 patients with ectopic pregnancies treated with methotrexate according to a single-dose protocol from January 2009 until November 2019. The diagnosis of ectopic pregnancy was made using a combination of transvaginal scan and serial serum β-hCG levels. Their clinical and demographic data were reviewed. Serum β-hCG levels were measured at pre-and post-treatment to determine the rate of successful resolution. Results The overall success rate was 87.7% (64/73 patients) with methotrexate treatment. Fifty-six patients (76.7%) were successfully treated with a single dose of methotrexate, and eight patients (11.0%) required a second dose of methotrexate. There was no relation between socio-demographic, pre-treatment β-hCG levels, ectopic mass size, and treatment efficacy. Smaller size of ectopic pregnancy (adjusted OR=29.23; 95% CI: 2.69, 317.90; P=0.006) and absence of free fluid at the pouch of Douglas (POD) (adjusted OR=27.31; 95% CI: 2.84, 262.32; P=0.004) was found to increase the likelihood of overall treatment success. Absence of fetal cardiac activities was found to increase the likelihood of first-dose methotrexate treatment success (OR=10.20; 95% CI: 1.93, 53.79; P=0.006). Conclusions Early diagnosis of ectopic pregnancy may reduce morbidity and mortality. In carefully selected cases, methotrexate treatment has been proven to be cost-effective and avoided risks associated with surgery and anaesthesia.

Research paper thumbnail of A Review on Magnetic Induction Spectroscopy Potential for Fetal Acidosis Examination

Sensors, 2022

Fetal acidosis is one of the main concerns during labor. Currently, fetal blood sampling (FBS) ha... more Fetal acidosis is one of the main concerns during labor. Currently, fetal blood sampling (FBS) has become the most accurate measurement of acidosis detection. However, it is invasive and does not provide a real time measurement due to laboratory procedures. Delays in diagnosis of acidosis have caused serious injury to the fetus, especially for the brain and the heart. This paper reviews the new technique in diagnosis of acidosis non-invasively. Magnetic Induction Spectroscopy (MIS) has been proposed to be a new device for acidosis detection in recent years. This paper explains the basic principle of MIS and outlines the design specifications and design considerations for a MIS pH probe. It is expected that readers will gain a basic understanding of the development of a MIS pH probe from this review.

Research paper thumbnail of Placenta increta presenting with threatened miscarriage during the first trimester in rhesus-negative mother: a case report

Journal of Medical Case Reports, 2021

Placenta accreta is known to be associated with significant maternal morbidity and mortality—prim... more Placenta accreta is known to be associated with significant maternal morbidity and mortality—primarily due to intractable bleeding during abortion or delivery at any level of gestation. The complications could be reduced if placenta accreta is suspected in a patient with a history of previous cesarean delivery and the gestational sac/placenta is located at the lower part of the uterus. Then, a proper management plan can be instituted, and complications can be reduced. The diagnosis of placenta accreta in the first trimester of pregnancy is considered uncommon. A 34-year-old Malay, gravida 4, para 3, rhesus-negative woman was referred from a private hospital at 13 weeks owing to accreta suspicion for further management. She has a history of three previous lower-segment cesarean sections. She also had per vaginal bleeding in the early first trimester, which is considered to indicate threatened miscarriage. Transabdominal ultrasound revealed features consistent with placenta accreta sp...

Research paper thumbnail of Müllerian duct anomalies with term pregnancy: a case report

Journal of Medical Case Reports

Background Müllerian duct anomaly is a rare condition. Many cases remain unidentified, especially... more Background Müllerian duct anomaly is a rare condition. Many cases remain unidentified, especially if asymptomatic. Thus, it is difficult to determine the actual incidence. Müllerian duct anomaly is associated with a wide range of gynecological and obstetric complications, namely infertility, endometriosis, urinary tract anomalies, and preterm delivery. Furthermore, congenital anomalies in pregnant mothers have a high risk of being genetically transmitted to their offspring. Case presentation We report a case of a patient with unsuspected müllerian duct anomaly in a term pregnancy. A 33-year-old Malay woman with previously uninvestigated involuntary primary infertility for 4 years presented with acute right pyelonephritis in labor at 38 weeks of gestation. She has had multiple congenital anomalies since birth and had undergone numerous surgeries during childhood. Her range of congenital defects included hydrocephalus, for which she was put on a ventriculoperitoneal shunt; imperforate...